• KIEAE Journal
• /
• v.13 no.6
• /
• pp.23-28
• /
• 2013

Green Standard for Energy and Environmental Design(G-SEED) has been used for environmental friendly building certification since 2002. The certification criteria initialed with multi-residential building and now it expands to 10 criteria for new and existing building types. The purpose of this study is to understand current recognition of G-SEED from the survey of multi-complex residences in newtown. From the general question, 75.2% of responders answered the period of living term between 1~3 years, 58.6% lived in $102.48{\sim}132.23m^2$ residential area and 65.2% owned their residences. The 43.2% of respondents recognized that their residences gained G-SEED certification by G-SEED emblem(31.6%). This is the significant meaning to understand public recognition of G-SEED and how to approach the strategy for raising the G-SEED recognition. The responders expected positive influence for economical value from G-SEED and also 75.3% of responders agreed with that G-SEED would be a decision make to buy and rent their residences. Second, residents responded that the consideration issue for green building is energy & prevention of environmental pollution(27.7%) which carries equal concern in G-SEED criteria category. The result of this survey verifies that the current level recognition of G-SEED of the responder's perspectives still is not well-known but it confirmed they have a positive expectation. Therefore, from this result, G-SEED needs to draw road map with detail plans for developing G-SEED with public participation.

• Mycobiology
• /
• v.31 no.2
• /
• pp.81-85
• /
• 2003

Antifungal properties of methyl 2-benzimidazole carbamate(BMC) were investigated using 16 fungi. Cytotoxicity test of BMC revealed that the morphology of HeLa cells was considerably deformed even at the concentrations as low as 0.1 ppm. Minimum inhibitory concentration(MIC) values of BMC for 7 fungi among the 16 tested ones were lower than $1.95{\times}10^{-4}{\mu}g/ml$, while Aspergillus flavus showed an MIC value higher than 1.0 ${\mu}g/ml$. Tolerance induction against BMC was successful only for Paecilomyces farinosus LAR10, contrary to the expectation that tolerance would be induced for the fungi having high MIC values such as Aspergillus niger ATCC 9642 and A. flavus ATCC 9643. Spore germination of A. niger ATCC 9642 was suppressed by BMC. However the mycelial growth of the fungus once germinated was not retarded at all by BMC up to 8 MIC. Addition of lanosterol provided a remedy for the reduced germination rate of A. niger ATCC 9642 spores.

• Journal of Global Scholars of Marketing Science
• /
• v.4
• /
• pp.197-211
• /
• 1999

The purpose of the research is (1) to identify the usage of Quick Response technologies (QRT) by apparel retailers and the improvement of store attributes by QRT, and (2) to test a conceptual model which examines Consumer Satisfaction(CS) with apparel retail stores. A convenience sample of 32 retailers and 200 apparel consumers participated in the survey research. The most used technology is sales captured at the item level and the store attribute most improved by QRT is fast turnaround of goods. Disconfirmation(DC) (i.e., QRT based, non-QRT based attributes) had significant effects on CS with apparel retail stores. DC of QRT based attributes (e.g. reduced stockout) have more influence on CS than DC of non-QRT based attributes (e.g., location of store).

• Journal of the Chungcheong Mathematical Society
• /
• v.27 no.3
• /
• pp.475-477
• /
• 2014

Lee and Lim (2009) state three characterizations of Loamax, exponential and power function distributions, the proofs of which, are based on the solutions of certain second order non-linear differential equations. For these characterizations, they make the following statement : "Therefore there exists a unique solution of the differential equation that satisfies the given initial conditions". Although the general solution of their first differential equation is easily obtainable, they do not obtain the general solutions of the other two differential equations to ensure their claim via initial conditions. In this very short report, we present the general solutions of these equations and show that the particular solutions satisfying the initial conditions are uniquely determined to be Lomax, exponential and power function distributions respectively.

• Communications for Statistical Applications and Methods
• /
• v.26 no.5
• /
• pp.473-495
• /
• 2019

In this paper, a new extension of Lindley distribution has been introduced. Certain characterizations based on truncated moments, hazard and reverse hazard function, conditional expectation of the proposed distribution are presented. Besides, these characterizations, other statistical/mathematical properties of the proposed model are also discussed. The estimation of the parameters is performed through different classical methods of estimation. Bayes estimation is computed under gamma informative prior under the squared error loss function. The performances of all estimation methods are studied via Monte Carlo simulations in mean square error sense. The potential of the proposed model is analyzed through two data sets. A modified goodness-of-fit test using the Nikulin-Rao-Robson statistic test is investigated via two examples and is observed that the new extension might be used as an alternative lifetime model.

• Proceedings of the Korean Society for the Gifted Conference
• /
• 2003.05a
• /
• pp.137-138
• /
• 2003

Understanding how and why people differ is a fundamental, if distant, goal of research efforts to bridge psychological and biological levels of analysis. General fluid intelligence (gF) is a major dimension of individual differences and refers to reasoning and novel problemsolving ability. A conceptual integration of evidence from cognitive (behavioral) and anatomical studies suggeststhat gF should covary with both task performance and neural activity in specific brain systems when specific cognitive demands are present, with the neural activity mediating the relation between gF and performance. Direct investigation of this possibility will be a critical step toward a mechanistic model of human intelligence. In turn, a mechanistic model might suggest ways to enhance gF through targeted behavioral or neurobiological intervent ions, We formed two different groups as subjects based on their scholarly attainments. Each group consists of 20 volunteers(aged 16-17 years, right-handed males) from the National Gifted School and a local high school respectively. To test whether individual differences in general intelligence are mediated at a neural level, we first assessed intellectual characteristics in 40 subjects using standard intelligence tests (Raven's Advanced Progressive Matrices, Wechsler Adult Intelligence Scale, Torrance Tests of Creative Thinking) administered outside of the MR scanner. We then used functional magnetic resonance imaging (fMRl) to measure task-related brain activity as participants performed three different kinds of computerized reasoning tasks that were intended to activate the relevant neural systems. To examine the difference of neural activity according to discrepancy in general intelligence, we compared the brain activity of both extreme groups (each, n=10) of the participants based on the standard intelligence test scores. In contrast to the common expectation, there was no significant difference of brain region involved in high-g tasks between both groups. Random effect analysis exhibited that lateral prefrontal, anterior cingulate and parietal cortex are associated with gF. Despite very different task contents in the three high-g-low-g contrasts, recruitment of multiple regions is markedly similar in each case, However, on the task with high 9F correlations, the Prodigy group, (intelligence rank: >99%) showed higher task-related neural activity in several brain regions. These results suggest that the relationship between gF and brain activity should be stronger under high-g conditions than low-g conditions.

• Journal of Pharmaceutical Investigation
• /
• v.39 no.6
• /
• pp.411-416
• /
• 2009

The aim of this study was to investigate the frequency of the SNPs on PEPT1 exon 5 and 16 and to analyze haplotype frequency on PEPT1 exon 5 and 16 in Korean population. A total of 519 healthy subjects was genotyped for PEPT1, using pyrosequencing analysis and polymerase chain reaction-based diagnostic tests. Haplotype was statistically inferred using an algorithm based on the expectation-maximization (EM). PEPT1 exon 5 G381A genotyping revealed that the frequency for homozygous wild-type (G/G), heterozygous (G/A) and homozygous mutant-type (A/A) was 30.4, 53.4 and 16.2%, respectively. PEPT1 exon 16 G1287C genotyping revealed that the frequency for homozygous G/G, heterozygous G/C and homozygous C/C type was 88.8, 10.0 and 1.2%, respectively. Based on these genotype data, haplotype analysis between PEPT1 exon 5 G381A and exon 16 G1287C using HapAnalyzer and PL-EM has proceeded. The result has revealed that linkage disequilibrium between alleles is not obvious (|D'|=0.3667).

• Archives of Pharmacal Research
• /
• v.27 no.12
• /
• pp.1245-1252
• /
• 2004

Although ascorbate (vitamin C) has been shown to have anti-cancer actions, its effect on human hepatoma cells has not yet been investigated, and thus, the exact mechanism of this action is not fully understood. In this study, the mechanism by which ascorbate induces apoptosis using HepG2 human hepatoblastoma cells is investigated. Ascorbate induced apoptotic cell death in a dose-dependent manner in the cells, was assessed through flow cytometric analysis. Contrary to expectation, ascorbate did not alter the cellular redox status, and treatment with antioxidants (N-acetyl cysteine and N,N-diphenyl-p-phenylenediamine) had no influence on the ascorbate-induced apoptosis. However, ascorbate induced a rapid and sustained increase in intracellular $Ca^{2+}$ concentration. EGTA, an extracellular $Ca^{2+}$ chelator did not significantly alter the ascorbate-induced intracellular $Ca^{2+}$ increase and apoptosis, whereas dantrolene, an intracellular $Ca^{2+}$ release blocker, completely blocked these actions of ascorbate. In addition, phospholipase C (PLC) inhibitors (U-73122 and manoalide) significantly suppressed the intracellular $Ca^{2+}$ release and apoptosis induced by ascorbate. Collectively, these results suggest that ascorbate induced apoptosis without changes in the cellular redox status in HepG2 cells, and that the PLC-coupled intracellular $Ca^{2+}$ release mechanism may mediate ascorbate-induced apoptosis.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.15 no.5
• /
• pp.1630-1648
• /
• 2021

Owing to the unprecedented COVID-19 pandemic, the pharmaceutical industry has attracted considerable attention, spurred by the widespread expectation of vaccine development. In this study, we collect relevant topics from news articles related to COVID-19 and explore their links with two South Korean pharmaceutical indices, the Drug and Medicine index of the Korea Composite Stock Price Index (KOSPI) and the Korean Securities Dealers Automated Quotations (KOSDAQ) Pharmaceutical index. We use generalized Dirichlet-multinomial regression (g-DMR) to reveal the dynamic topic distributions over metadata of index values. The results of our analysis, obtained using g-DMR, reveal that a greater focus on specific news topics has a significant relationship with fluctuations in the indices. We also provide practical and theoretical implications based on this analysis.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.4
• /
• pp.1153-1157
• /
• 2011

A kinetic study is reported for aminolysis of S-4-nitrophenyl X-substituted thiobenzoates 3a-g in 80 mol % $H_2O$/20 mol % DMSO at $25.0{\pm}0.1^{\circ}C$. Thiol esters 3a-g are 7.8-47.6 fold more reactive than the corresponding oxygen esters (i.e., 4-nitrophenyl X-substituted benzoates 1a-g). Such reactivity order appears to be in accordance with the expectation that 4-nitrothiophenoxide in 3a-g is a better nucleofuge than 4-nitrophenoxide in 1a-g since the former is 2.64 pKa units less basic than the latter. Hammett plot for the reactions of 3a-g exhibit poor correlation coefficients ($R^2$ = 0.977-0.986) with negative deviation by substrates possessing an electrondonating group (EDG), while the Yukawa-Tsuno plots result in excellent linear correlation ($R^2$ = 0.995-0.997) with ${\rho}$ = 0.93-1.23 and r = 0.57-0.67, indicating that the negative deviation shown by substrates possessing an EDG is caused by ground-state stabilization through resonance interactions but not due to a change in ratedetermining step upon changing the nonleaving-group substituent X. The ${\rho}$ value increases as the incoming amine becomes more basic and more reactive, indicating that the RSP is not operative in the current reactions.