• Title/Summary/Keyword: G-Rh2

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Thermal Comfort of the Sports/Leisure Clothing with the Heat Storage/Reflection Function - Wearing Evaluation under the Condition of 0x00B1;1℃ and 50±5% RH - (축열/체열반사기능을 가진 스포츠 레저복의 온열쾌적성 - 0±1℃, 50±5% RH 환경에서의 착의평가 -)

  • Kim, Tae-Gyou;Song, Min Kyu;Lee, Chang Min;Kwon, Oh Kyung
    • Fashion & Textile Research Journal
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    • v.20 no.4
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    • pp.474-481
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    • 2018
  • For this study, we developed clothing in which textile materials that were excellent weather control function for the cold environment and we performed the human subject test with developed clothing to determine the thermal comfort. We used 2 clothing samples developed (A and B, hollow yarn+moisture absorption/quick drying yarn, 3 layers, high stretchable, heat reflection film and lamination treated) and a control sample (Ctrl.) for the human subject test and 8 adult males were used as a human subjects and environmental conditions of chamber were $0{\pm}1^{\circ}C$. $50{\pm}5%RH$, 0.3m/sec. The results were as follows: The average skin temperature and hand, thigh temperature of B were higher than B and Ctrl. (p<.05). The micro-climates of B were near to thermal comfort range which is $32{\pm}1^{\circ}C$ and $50{\pm}10%\;RH$. The chest temperature of B was significantly higher than others (p<.05). The relative humidity of B was lower than others and kept stable rather than others. The thermal sensation of B was near the "neutral" and was significantly different from Ctrl. (p<.01) and the weight loss of B was lower than Ctrl. (p<.05). The counting task and hand temperature was positively related and the counting task value of B and A is bigger than Ctrl. and that of A was bigger than Ctrl. (p<.05).

Pulsatile GnRH Therapy in Male Patients with Hypogonadotropic Hyprogonadism (GnRH의 맥동성 투여에 의한 남성 성선기능저하증의 치료)

  • Park, Ki-Hyun;Jee, Yong-Seok;Lee, Byung-Seok;Lee, Bo-Yun;Cho, Dong-Jae;Song, Chan-Ho;Lee, Moo-Sang;Choi, Hyung-Ki;Lee, Hyun-Chul;Heo, Kab-Beom
    • Clinical and Experimental Reproductive Medicine
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    • v.19 no.1
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    • pp.81-85
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    • 1992
  • The effects of pulsatile GnRH therapy have been studied for the treatment of different forms of hypogonadotropic hypogonadism, including idiopathic hypogonadotropic hypogonadism and hypogonadism developed as a result of treatment with combination of surgery and irradiation for pituitary or hypothalamic tumor. GnRH was administered subcutaneously in a dose of $10{\mu}g$ every 2 hours with the pulsatile infusion pump. With GnRH therapy, all patients improved secretion of LH, FSH and testosterone. Testicular volumes increased. Spermatogenesis was induced in 8 patients. Pulsatile GnRH therapy is an effective treatment for idiopathic hypogonadotropic hypogonadism and can have a role in hypogonadism previously treated with combination of surgery and irradiation for pituitary or hypothalamic tumor.

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GABAA Receptor- and Non-NMDA Glutamate Receptor-Mediated Actions of Korean Red Ginseng Extract on the Gonadotropin Releasing Hormone Neurons

  • Cho, Dong-Hyu;Bhattarai, Janardhan Prasad;Han, Seong-Kyu
    • Journal of Ginseng Research
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    • v.36 no.1
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    • pp.47-54
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    • 2012
  • Korean red ginseng (KRG) has been used worldwide as a traditional medicine for the treatment of various reproductive diseases. Gonadotropin releasing hormone (GnRH) neurons are the fundamental regulators of pulsatile release of gonadotropin required for fertility. In this study, an extract of KRG (KRGE) was applied to GnRH neurons to identify the receptors activated by KRGE. The brain slice patch clamp technique in whole cell and perforated patch was used to clarify the effect of KRGE on the membrane currents and membrane potentials of GnRH neurons. Application of KRGE (3 ${\mu}g$/${\mu}L$) under whole cell patch induced remarkable inward currents (56.17${\pm}$7.45 pA, n=25) and depolarization (12.91${\pm}$3.80 mV, n=4) in GnRH neurons under high $Cl^-$ pipette solution condition. These inward currents were not only reproducible, but also concentration dependent. In addition, inward currents and depolarization induced by KRGE persisted in the presence of the voltage gated $Na^+$ channel blocker tetrodotoxin (TTX), suggesting that the responses by KRGE were postsynaptic events. Application of KRGE under the gramicidin perforated patch induced depolarization in the presence of TTX suggesting its physiological significance on GnRH response. Further, the KRGE-induced inward currents were partially blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; non-NMDA glutamate receptor antagonist, 10 ${\mu}M$) or picrotoxin (PIC; $GABA_A$ receptor antagonist, 50 ${\mu}M$), and almost blocked by PIC and CNQX mixture. Taken together, these results suggest that KRGE contains ingredients with possible GABA and non-NMDA glutamate receptor mimetic activity, and may play an important role in the endocrine function of reproductive physiology, via activation of $GABA_A$ and non-NMDA glutamate receptors in GnRH neurons.

Control of Spinach Downy Mildew by Forced Ventilation in Greenhouse Cultivation (강제환기처리에 의한 비닐하우스재배 시금치의 노균병 발생 억제)

  • Park, Seok-Hee;Lee, Joong-Hwan;Woo, Jin-Ha;Choi, Seong-Yong;Park, So-Deuk;Moon, Yong-Sun
    • Korean Journal of Organic Agriculture
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    • v.22 no.1
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    • pp.147-154
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    • 2014
  • Spinach downy mildew caused by Peronospora spinaciae is the main reason of yield reduction in Korea as well as in worldwide. After forced ventilation or horizontal air circulation fans were installed to control growth conditions in green house, the changes of temperature, relative humidity (RH), growth and yield, and occurrence of downy mildew were examined. Althought here was no significant difference of temperature between the treatments, RH as 9.2% lower at nighttime by forced ventilation. In addition, final fresh weight was increased to 17.8g compared to control (10.1g), which as 7.7g enhancement. Downy mildew s tarted to show 20 days after sowing (DAS) and increased to 34.7% at 60 DAS on harvest time in control. In contrast downy mildew was occurred 40 DAS with 0.7% incidence rate and 4% at harvest by forced ventilation. The results indicated that reduction of only 9.2% of RH at nighttime by forced ventilation in greenhouse spinach growth was dramatically thrived over 76.2%. Additionally spinach downy mildew occurred 20 days later with extremely lower incident rate, which meant 88.5% reduction of downy mildew.

Quality Characteristics of Ginseng Coffee Treated by Coating of White Ginseng Extract

  • Kim, Kyung-Tack;Lee, Young-Chul;Cho, Chang-Won;Rhee, Young-Kyoung;Bae, Hye-Min
    • Journal of Ginseng Research
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    • v.34 no.1
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    • pp.1-7
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    • 2010
  • The quality attributes of coffee treated with different concentrations of white ginseng extract were examined. Increased concentration of white ginseng extract was associated with higher color values (Hunter L. a, b scale). The crude saponin contents of untreated roasted coffee beans (control) and those coated with $5^{\circ}$ Brix (WGC-1) and $20^{\circ}$ Brix white ginseng extract (WGC-2) were 8.29%, 8.74%, and 8.93%, respectively. The total ginsenoside contents of WGC-1 and WGC-2 were 0.3 mg/g and 0.6 mg/g, respectively. In the case of major ginsenosides, the contents of ginsenosides $Rg_1,\;Rg_2,\;Rb_1,\;Rb_2,\;Rg_2,\;Rh_1$, and $Rg_3$ increased directly with the concentration of white ginseng extract. Total sugar and acidic polysaccharide contents also increased directly with the concentration of white ginseng extract. The coffee beans coated with ginseng extract scored significantly higher ginseng taste scores than the control (p<0.005) in sensory evaluation. In terms of coffee taste, WGC-2 had significantly lower scores than the commercial coffee bean. In the consumer sensory evaluation, overall preference did not differ significantly among the treatments.

Treatment of Hyperestrogenism Caused by follicular Cysts in a Dog (개에서 난포낭종에 의해 발생한 고에스트로겐증의 치료)

  • Lee Jong Hwan;Kang Hyun-Gu;Kim Ill-Hwa;Eum Kyung Hwan;Lee Kee-Chang;Lee Chung-San;Lee Dong-Yub
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.428-430
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    • 2005
  • A female French Bulldog was referred to Veterinary Medical Teaching Hospital, Chungbuk National University. In case, alopecia and erythema nodosum were the main complaints in a 16 months old female dog. Ventral alopecia and dorsal erythema nodosum have been presented on skin lesions for 8 months. There were no specific change with CBC and blood chemistry but plasma estrogen concentration was 68 pg/ml and cornified superficial epithelial cells were detected above $90\%$ by cytology examination of vaginal smear preparation. Ovarian cyst was detected by ultrasonography in the left ovary. Cystic diameter was $14.2\times12.0mm$. Therefore, we diagnosed as unilateral multiple follicular cysts. The dog was treated with GnRH $50{\mu}g$ injection by intramuscularly Cyst size was decreased $7.3\times7.2mm$ after 7 days GnRH treatment and disappeared after 14 days GnRH treatment. Also dermatitis by unilateral multiple follicular cysts were recovered after 21 days GnRH treatment.

Effects of Storage Conditions on Weight Loss and Free Sugar Composition of Fresh Ginseng (보관조건에 따른 수삼의 중량과 유리당 조성 변화)

  • Chang, Jin-Kyu;Kim, Cheon-Sug;Nho, Kil-Bong;Cho, Byung-Goo
    • Journal of Ginseng Research
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    • v.29 no.2
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    • pp.113-118
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    • 2005
  • This study was to examine the effect of the opening ratio (area of spile hole/total surface area) of plastic container and storage temperature on physicochemical changes of fresh ginseng. At room temperature ($19\~23^{\circ}C$, RH $40\~61\%$), fungi and spoilage were observed 4 and 10 days, respectively after storing the fresh ginseng in a closed container. In storage container with $1\%$ opening ratio, fungi appeared 8 days after storage. In the container with $5\%$ and $10\%$ opening ratio, fresh ginseng showed excessive loss of moisture on the surface only after 4 days. The weight loss was most remarkable in the container with 5 and $10\%$ opening ratio. Content of maltose and sucrose decreased gradually in accordance with storage time but the extent of decreasing ratio was less significant in the container with lower opening ratio. At low temperature $(4\~9^{\circ}C,\;RH\;72\~92\%)$, no fungi but $10\%$ loss of weight was observed in the container with $5\%$ and $10\%$ opening ratio after 12 days storage. But in the tightly closed container and $1\%$ opening ratio for spiting, fresh ginseng showed good appearance even after 30 days of storage. Free sugars, especially maltose revealed gradual decrease but sucrose gradually increase following decrease at the beginning. This result suggests that storage condition of low temperature and opening ratio of plastic box less than $1\%$ can extend storage span of fresh ginseng significantly.

Color Removal of Rhodamine B by Photoelectrocatalytic Process Using Immobilized TiO2 (고정화 광촉매를 이용한 광전기촉매 공정에서 Rhodamine B의 색도 제거)

  • Kim, Dong-Seog;Park, Young-Seek
    • Journal of Environmental Health Sciences
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    • v.34 no.3
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    • pp.226-232
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    • 2008
  • A feasibility study for the application of the photoelectrocatalytic decolorization of Rhodamine B (RhB) was performed in a photoelectrochemical reactor with immobilized $TiO_2$ particle. The effects of operating conditions, such as current, electrolyte and pH were evaluated. The experimental results showed that optimum $TiO_2$ dosage and current in the photoelectrocatalytic process were 83.3 g/l and 0.5 A, respectively. It was found that the RhB could be degraded more efficiently by this photoelectrocatalytic process than the sum of the two individual oxidation processes (photocatalytic and electrolytic process). The addition of NaCl increased the initial decolorization rate and reduced reaction time. The optimum dosage of NaCl was 0.15 g/l. The decolorization rate of the photoelectrocatalytic process increased sharply with a decrease in pH value. However when the NaCl was added, the pH effect was not high.

Relationship between Weather Factors and Chemical Components of Flue-cured Tobacco (기상요인과 황색종 잎담배의 화학성분과의 관계)

  • Kim Sang-Beom;Cho Soo-Heon;Chung Youl-Young;Jeong Kee-Taeg
    • Journal of the Korean Society of Tobacco Science
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    • v.26 no.2 s.52
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    • pp.93-101
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    • 2004
  • This study was conducted to investigate the relationship between weather factors during the growing season and chemical components of flue-cured tobacco. Chemical components used in this study was from 'Farm Leaf Tobacco Test' conducted at KT&G Central Research Institute from 1986 through 2003. Data of weather factors during growing season(April to July) were collected in 10 districts measured at Korea Meteorological Adminstration(KMA). Nicotine and total sugar contents, and total sugar to nicotine(TS/Nic.) ratio were increased, whereas total nitrogen to nicotine(TN/Nic.) ratio and chloride content were decreased from 1986 through 2003. Year to year variation of rainfall was the largest, followed by that of sunshine hour. Month to month variation of rainfall also was the largest, followed by that of mean daily air temperature(MDAT). Rainfall was correlated positively with relative humidity(RH), but negatively with sunshine hour. Nicotine content was correlated positively with MDAT(in July, June$\~$July, May$\~$July and average), but negatively with rainfall(in May$\~$July) and with RH(in June, July, May $\~$June, June $\~$July, April$\~$June, May $\~$July and average). Total sugar content was correlated positively with MDAT(in May), but negatively with sunshine hour(average) and RH(in June, July, June$\~$July, April$\~$June, May$\~$July and average). The positive correlation was found between total nitrogen content and sunshine hour(in April, May, April$\~$May, May$\~$July, April$\~$June and average). The negative correlation was found between TS/Nic. ratio and sunshine hour(in May$\~$July and average). TN/Nic. ratio was correlated positively with sunshine hour(in May and April$\~$May) and with RH(in July and June$\~$July), but negatively with MDAT(in July, June$\~$July, May$\~$July and average). Ether extraction content was correlated positively with MDAT(in July, June$\~$July, May$\~$July and average) and with sunshine hour(in July and June$\~$July), but negatively with rainfall(in April, July, May­July and average). Chloride content was correlated positively with sunshine hour(in April, July, April$\~$May, June$\~$July, April$\~$June, May$\~$July and average), but negatively with rainfall(in April, April$\~$June and average).

Ginsenoside derivatives and quality characteristics of fermented ginseng using lactic acid bacteria (유산균을 이용한 발효인삼의 ginsenoside 유도체 및 품질특성)

  • Kang, Bok-Hee;Lee, Kun-Jae;Hur, Sang-Sun;Lee, Dong-Sun;Lee, Sang-Han;Shin, Ki-Sun;Lee, Jin-Man
    • Food Science and Preservation
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    • v.20 no.4
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    • pp.573-582
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    • 2013
  • This study was done in order to investigate the bioconversion of ginsenoside, as well as the quality characteristics of fermented ginseng, by using lactic acid bacteria. Quality characteristics such as the thin layer chromatography(TLC) pattern, ginsenosides, total phenolic content, electron donating ability, and total sugar of fermenting ginseng and red ginseng were analyzed. The ginsenoside Rg2r, Rh2s and Rh2r of the fermented ginseng and red ginseng for 65 hours at a temperature of $37^{\circ}C$ were not detected. The ginsenoside Rg1 and Re contents have decreased, while the Rh1, Rg2s, Rd, Rg3r, and Rg3s have increased due to fermentation. The ginsenoside Rg3 of the fermented red ginseng has increased and the contents were $114.83{\sim}131.68{\mu}g/mL$ (control $104.56{\mu}g/mL$). The total phenolic content and electron donating ability of the red ginseng have totally decreased after 7 days of fermentation. The total phenolic contents of the fermented ginseng and red ginseng with different lactic acid bacteria did not show any tendency as different strains. The electron donating ability of the fermented ginseng has increased; however, the electron donating ability of the red ginseng has decreased. The total sugars of the fermented ginseng and red ginseng with different lactic acid bacteria have also decreased.