• Title/Summary/Keyword: G/I ratio

Search Result 998, Processing Time 0.029 seconds

Determination of Serum Thyroxine Levels in Normal Korean Subjects and Various Thyroid Diseases (정상인 및 각종 갑상선 질환 환자의 혈청 Thyroxine)

  • Kim, Dong-Jip;Min, Byong-Sok;Bahk, Yong-Whee;Kim, Boo-Sung
    • The Korean Journal of Nuclear Medicine
    • /
    • v.3 no.2
    • /
    • pp.33-38
    • /
    • 1969
  • The serum thyroxine levels were measured by method of Tetrasorb Kit in 69 subjects including 13 subjects in euthyroid state, 31 with hyperthyroidism, 5 with hypothyroidism, 13 with nontoxic diffuse goiter, and 7 with nontoxic nodular goiter. Three parameters of the thyroid function test including thyroxine ($T_4$) levels, $^{131}I$ uptake (24 hrs) values and $PB^{131}I$ conversion ratio were correlated with clinical manifestations and courses of the disease. 1. The serum $T_4$ levels in the normal subjects were in range of $6.0{\mu}g/dl\;to\;14.4{\mu}g/dl$. (The mean $9.4{\mu}g/dl$). 2. The diagnostic compatibility of the serum $T_4$ was 93.5% in hyperthyroidism, 100% both in hypothyroidism and in nontoxic diffuse goiter, 86% in nontoxic nodular goiter, or 95.8% in the entire series. (Table 1). 3. The diagnostic compatibility of $^{131}I$ uptake (24 hrs) values and $PB^{131}I$ conversion ratio were less than the serum $T_4$ levels as summarized in Tables 2 & 3. The serum $T_4$ determination by Tetrasorb Kit is a simple, accurate and very useful test of the thyroid function.

  • PDF

Effects of Epidermal Growth Factor and Insulin-like Growth Factor-I on Placental Amino Acids Transport Activities in Rats

  • Ono, Kenichiro
    • Proceedings of the Korean Society of Embryo Transfer Conference
    • /
    • 2002.11a
    • /
    • pp.34-36
    • /
    • 2002
  • Epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) have been shown to stimulate proliferation and differentiation of various somatic cells, including placental trophoblasts and also to enhance fetal growth and development when maternally administered. Since an increase of the expression of placental EGF and IGF-I receptors in rat, mouse, and human with the gestation advanced, both EGF and IGF-I were considered to play pivotal roles on fetal growth by regulating some function of placental cells. Amino acids are crucial importance for both maternal and fetal requirements of energy source and essential constituent of fetal mass during pregnancy. Impaired fetal and placental uptake of amino acids has been observed in several models of growth retardation in the rat. Amino acid is concentrated in the fetal side through active transport by amino acid transporters and is one of the important metabolic fuels for the fatal growth. Therefore, at first plasma amino acid concentrations in mothers and fetuses were measured as an index of uphill transport across the placenta associated with EGF and IGF-1. The EGF administration at the concentration of 0, 0.1, or 0.2 $\mu\textrm{g}$/g to pregnant rats from day 18 to 21 of gestation apparently increased fetal/maternal ratio of serum proline concentration and also fatal growth in EGF dose-dependent manner. When IGF-I in doses of 0, 1, 2, and 4 $\mu\textrm{g}$/g were administrated, the ratio of leucine, isoleucine, tryptophan, phenylalanine, tyrosine and also fetal growth significantly increased with a dose-dependent manner. These results suggested that EGF and IGF-I enhanced fatal growth by, as one of its possible mechanisms, promoting placental activity to transfer some amino acid supplies from the mother to the fetus in late pregnancy.

  • PDF

Context-sensitive lingual gestures in the Korean tap /r/

  • Kim, Dae-Won
    • Speech Sciences
    • /
    • v.7 no.3
    • /
    • pp.11-19
    • /
    • 2000
  • The present electropalatographic study reports the production of the allophones. i.e., [l] and [r], of Korean tap /r/ and their coarticulatory characteristics in /$C{\'{a}}r#g$/ and /$C{\'{a}}r#i$/ sequences. The finding that tap /r/ involves a complete oral closure with less lingual contact, i.e., apico-frontalveolar coupling. than lateralized /r/ which involves apico-bladealveolar coupling and tongue dorsum lowering for adequate airflow through either side and/or both of the tongue body suggests that the two allophones of the tap /r/ have different lingual gestures. Moreover. in comparison with the tap. the lateral exerts longer lingual contacts. The mean ratio between them is 3.7. In the sequences /Car#g/. the two adjacent antagonistic segments (i.e., /r/ and /g/) show mutual coarticulation effects taking on features of adjacent segment. but either of them is precisely constrained without blocking the formation of involved major lingual gestures for the other segment. In sequences /Car#i/ occurs anticipatory V-to-C coarticulation but not vocalic carryover effects. In both sequences. the allophones reveal insignificant wordinitial consonantal carryover coarticulatory effects and insignificant speaker-specific lingual contacts.

  • PDF

The Prediction Method of the Small Strain Shear Modulus for Busan Clay Using CPT and DMT (CPT와 DMT를 이용한 부산점토의 최대전단탄성계수 추정방법에 관한 연구)

  • Hong, Sung-Jin;Yoon, Hyung-Ko;Lee, Jong-Sub;Lee, Woo-Jin
    • Journal of the Korean Geotechnical Society
    • /
    • v.25 no.6
    • /
    • pp.5-16
    • /
    • 2009
  • The is study is to evaluate the small strain shear modulus ($G_{max}$) of Busan clay using in-situ penetration tests. A series of dilatometer tests (DMT) and piezocone penetration tests (CPTu) are performed at Busan newport and Noksan sites, and hybrid oedometer tests are also carried out on the specimens obtained from both sites. The $G_{max}$ is evaluated from the shear wave velocity ($V_s$) measured by the bender elements installed at the boundary of oedometer cell. By analyzing these data, the relationship of $G_{max}$ and state variables, such as confined stress and void ratio, is developed. The analysis of lab and in-situ test results reveals that the ratio of $G_{max}$ to $q_t$ is inversely proportional to the plasticity index while the ratio of $G_{max}$ to $E_D$ has a linear relationship with ($I/I_D$)$(p_a/{\sigma}'_v)^{0.5}$. Two correlations suggested in this study, based on CPT and DMT results, appear to provide reasonable predictions of the small strain shear modulus.

A Study on the Effective Free Surface of Fluid Cargo (유동화물의 유효자유표면에 관한 연구)

  • Hur, I.;Wang, J.S.
    • Journal of the Korean Institute of Navigation
    • /
    • v.11 no.2
    • /
    • pp.73-88
    • /
    • 1987
  • It is well known that the height of tank metacenter above the centroid of fluid in a tank is given by i/v where I is the inertia moment of free surface and v is the fluid volume. It is supposed in this formula that the inclination of ship is small and that the free surface of fluid do not touch the top and the bottom of tank. It the inclination of ship is large, the height of tank metacenter may be possibly greater than that given by i/v. The height of tank metacenter is smaller than i/v when the free surface of fluid touch the top or the bottom of tank. The reasonable method to calculate the height of tank metacenter is presented in this paper and prepared in FORTRAN program by FUNCTION EFFRES. The approximate formula was also developed and given by $g_m=(1+\frac{2}{1}tan^2\theta)[1-EXP\{-12(\frac{\alpha(1-\alpha)k}{tan\theta})^{1.25}\}]\frac{i}{v}$ where $g_m$ is the distance from the centroid of fluid to the tank metacenter, $\theta$ is inclined angle of ship, $\alpha$ is the ratio of filled volume to tank capacity and k is the ratio of the depth to the width of tank. The values calculated by the approximate formula given in this paper were compared with the exact values from the computer program and proved out to be sufficiently precise for practical use.

  • PDF

A Study of the Flow Phenomenon of Water in a Channel with Flat Plate Obstruction Geometry at the Entry

  • Khan, M.M.K.;Kabir, M.A.;Bhuiyan, M.A.
    • Journal of Mechanical Science and Technology
    • /
    • v.17 no.6
    • /
    • pp.879-887
    • /
    • 2003
  • The flow in a parallel walled test channel, when obstructed with a geometry at the entrance, can be forward, reverse and stagnant depending on the position of the obstruction. This interesting flow phenomenon has potential benefit in the control of energy and various flows in the process industry In this experiment, the flat plate obstruction geometry was used as an obstruction at the entry of the test channel. The parameters that influence the flow inside and around the test channel were the gap (g) between the test channel and the obstruction geometry, the length (L) of the test channel and the Reynolds number (Re). The effect of the gap to channel width ratio (g/w) on the magnitude of the velocity ratio (V$\_$i/ / V$\_$o/ : velocity inside/ velocity outside the test channel) was investigated for a range of Reynolds numbers. The maximum reverse flow observed was nearly 20% to 60% of the outside velocity for Reynolds number ranging from 1000 to 9000 at g/w ratio of 1.5. The maximum forward velocity inside the test channel was found 80% of the outside velocity at higher g/w ratio of 8. The effect of the test channel length on the velocity ratio was investigated for different g/w ratios and a fixed Reynolds number of 4000. The influence of the Reynolds number on the velocity ratio is also discussed and presented for different gap to width ratio (g/w). The flow visualisation photographs showing fluid motion inside and around the test channel are also presented and discussed.

Effects of Supplementing Different Combinations of Nitrogen Supplements on Digestibility and Performance in Sheep Fed Wheat Straw Diets

  • Li, Yong;Li, Defa;Xing, Jianjun;Li, Shengli;Han, Yang;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.15 no.10
    • /
    • pp.1428-1432
    • /
    • 2002
  • Thirty-six (20 wethers and 16 rams) adult Gansu highland finewool sheep with an average liveweight of $19.42{\pm}1.83kg$ were used. The sheep were allocated to 4 treatments and confined in individual feeding stalls. The 80 day feeding trial was divided into 2 periods of 38 and 42 days. The sheep had access to clean water and were fed chopped wheat straw ad libitum. Daily supplemented diets of 150 g for the first period and 200 g for the later period were provided. The 4 types of supplements were: Wheat bran type (I), which is the traditional feeding practice in the area and the control group; Linseed cake type (II); Linseed cake+poultry litter type (III); Poultry litter+distiller grains type (IV). The digestibility trial was conducted using a total collection method at the end of the first period in the feeding trial. The results showed that the digestibilities of DM, OM, CP, CF, NDF and ADF in group II and III were increased to more than 50%. CP and NDF digestibility in group II were significantly increased by 23.6% and 25.5% respectively over group I (p<0.01) and by 10.1% and 13.1% respectively over group III (p<0.05). The digestibility of DM, OM, CP, CF, NDF and ADF in group IV was lower than group I by 4.4 to 8.4% (p>0.05). Compared to group I, group II and III increased straw intake by 17.6% (p<0.01) and 10.8% (p<0.05). The ADG increased from 16.2 g in group I to 45.3 g and 32.8 g (p<0.01) in group II and III respectively. The ratio of supplement intake to gain decreased from 10.7 in group I to 3.9 and 5.4 (p<0.01) in group II and III respectively. The ratio of supplement cost to gain also decreased by 60.0% and 64.3%, respectively. The wool growth rate and wool strength in these 2 groups were noticeably improved. This significantly enhanced the wool's textile value. The above parameters in group IV were lower than in group I, except the ratio of supplement cost to gain. This research indicates that local low quality nitrogen resources could be used effectively and economically to improve the utilization of wheat straw fed to sheep on smallholder farms under harsh loess plateau conditions in the winter.

The Endocrine Changes and Alteration of the Ovarian Response to Clomiphen Citrate after Laparoscopic Laser Vaporization in Patients with Polycystic Ovary Syndrome (다낭성 난포 증후군 환자에서 복강경적 Laser Vaporization 후 내분비적 변화 및 클로미펜에 대한 난소 반응성의 변화)

  • Lee, Sang-Joon;Kim, Jin-Young;Park, Ki-Hyun;Choi, Kyu-Hong
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.26 no.3
    • /
    • pp.483-490
    • /
    • 1999
  • Objectives: Polycystic ovary syndrome (PCOS) has the feature of excessive LH, hyperandrogenism and disturbance of folliculogenesis. Also, insulin, IGF-I and IGFBP-l are involved in the pathogenesis of PCOS. Various surgical and medical therapies have been used and the action mechanisms are related to the endocrine effect. Laparoscopic ovarian electrocautery or laser vaporization is effective in the restoration of ovulation and normal menstrual cycle with minimal invasive procedure especially in the patients resistant to medical therapy. Clomiphen citrate (CC) is used for the ovulation induction in pcas and the resistance is known to be related to insulin, IGF-I, IGFBP-l levels. This study was performed to evaluate the effect of the laparoscopic laser vaporization on the levels of LH, FSH, testosterone, IGF-I and IGFBP-l and on the ovarian response to clomiphen citrate in patients with CC-resistant PCOS. Materials and Methods: The fasting basal serum LH, FSH, testosterone, IGF-I and IGFBP-l level were measured in 10 PCOS patients with CC-resistance and 7 normal controls with regular menstrual cycle. In PCOS, after laparoscopic $CO_2$ laser vaporization, endocrine levels were measured in 1 week interval for 4 weeks and then compared with preoperative levels. Results: In PCOS group, mean serum LH/FSH ratio, testosterone, IGF-I levels were higher and IGFBP-l level was lower than control. LH/FSH ratio decreased from $2.51{\pm}0.67$ to $1.7{\pm}0.6$ (p<0.05) in 2 weeks, to $0.56{\pm}0.2$ (p<0.01) in 3 weeks and to $1.41{\pm}0.3$ (p<0.01) in 4 weeks after operation. Testosterone level decreased from $1.51{\pm}0.82ng/ml$ to $0.65{\pm}0.34ng/ml$ (p<0.05) in 2 weeks, to $0.56{\pm}0.67ng/ml $(p<0.01) in 3 weeks after operation. IGF-I level also decreased from $436{\pm}47.5{\mu}g/l$ to $187{\pm}38{\mu}g/l$ (p<0.0l) in 1 week, to $167{\pm}42{\mu}g/l$ (p<0.01) in 2 weeks, $179{\pm}55{\mu}g/l$ (p<0.01) in 3 weeks and to $120{\pm}43{\mu}g/l$ (p<0.01) in 4 weeks after operation. IGFBP-l level showed no significant change. In 8 of 10 PCOS patients, ovulation was induced with low dose clomiphen citrate. Conclusion: Laparoscopic $CO_2$ laser vaporization restores normal menstrual cycle and ovulation through endocrine effect of decreasing LH/FSH ratio, testosterone and IGF-I level and increases the response to CC. Therefore it is useful for restoration of normal menstruation and induction of ovulation in CC resistant PCOS patients.

  • PDF

The Effect of External Medium on Serum Protein of Fresh Water Fish(I) (담수산어류의 혈청단백질에 미치는 환경수의 영향(I))

  • 이용억;김익태
    • The Korean Journal of Zoology
    • /
    • v.8 no.2
    • /
    • pp.28-32
    • /
    • 1965
  • It is well known that many kinds of chemical or metalic agent which were ionized or undissociated at toxified external medium and remarkable effect occurred to the fresh water fish. The effects of hydrogen ion concentration on serum protein of fresh water fish, (phycephalus argus CANTOR) had not been reported yet. In this point, authors attempted to study the changes of A/G ratio, total protein, hemoglobin, hematocrit, RBC , liver and kidney weight of snake head in the above environment. 95 snake heads were subjected to external medium with PH-4.5 and A/G ratio, hematocrit, hemoglobin, total protein, RBC, and liver & kidney weight were measured at 32.80, 15202000 and 272 hours respectively. In whole experimental period, L 1 and L2 globulin increased, on the other, albumin decreased as compare with control . Hence, the A/G ratio decreased remarkably . Though, total protein increased prominently through the whole experimental period, hematocrit, hemoglobin, RBC, increased only at 80 hours, and then decreased as compared to the control. Liver weight revealed distinctive increase at 80 hours, but no remarkable change could be seen there after. Hence, kidney weight revealed continuous rise. By these results, it may be said that as snake head were subjected to external medium with PH-4.5, this environmental factor influenced protein metabolism , blood component and organs.

  • PDF

Effects of Thermal Treatment on Structural Properties of DLC Films Deposited by FCVA Method (FCVA 방법으로 증착된 DLC 박막의 열처리에 따른 구조적 물성 분석)

  • 김영도;장석모;박창균;엄현석;박진석
    • The Transactions of the Korean Institute of Electrical Engineers C
    • /
    • v.52 no.8
    • /
    • pp.325-329
    • /
    • 2003
  • Effects of thermal treatment on the structural properties of diamond-like carbon (DU) films were examined. The DLC films were deposited by using a modified filtered cathodic vacuum arc (FCVA) deposition system and by varying the negative substrate bias voltage, deposition time, and nitrogen flow rate. Thermal treatment on DLC films was performed using a rapid thermal annealing (RTA) process at $600^{\circ}C$ for 2min. Raman spectroscopy, x-ray photoemission spectroscopy (XPS), atomic force microscope (AFM), and surface profiler were used to characterize the I$_{D}$I$_{G}$ intensity ratio, sp$^3$ hybrid carbon fraction, internal stress, and surface roughness. It was found for all the deposited DLC films that the RTA-treatment results in the release of internal compressive stress, while at the same time it leds to the decrease of sp$^3$ fraction and the increase of I$_{D}$I$_{G}$ intensity ratio. It was also suggested that the thermal treatment effect on the structural property of DLC films strongly depends on the diamond-like nature (i.e., sp$^3$ fraction) of as-deposited film.ed film.