• Korean Institute of Interior Design Journal
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• v.20 no.5
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• pp.245-253
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• 2011

As interests towards health rapidly increase recently, interests and demand for hospital interior space are increasing as well. Therefore, most of today's hospitals that have been functionally designed are transforming into healing environments that consider psychological aspects, in order to assist patients forget about fear, desperation and have peace of mind. With such creation method of healing environment, natural elements can be applied to spaces in order to allow patients feel vitality, hope and adapt positive thinking, and these can eventually lead to affluent fusion of humans, nature and space. Through case analyses of how natural elements are applied to hospital's interior space, this study understands its characteristics. According to the findings, nature is largely classified into light, water, plant, stone/soil, and its application methods can be classified into center, transition, continuity, division, opening and closure. As evident from case analyses, application of natural elements to hospital's interior space promotes exchanges among patients through community formation, and achieves the effect of spatial concentration and public place. Also, ambiguity of exterior and interior boundary creates a sense of expansion and continuous effect, and can also provide a healing environment that can fully absorb natural environment open to patients. This study aims to be of service when designing hospital's interior space, with its natural element application method for healing environment research, and wishes for continuous studies on healing environments with more diverse methods.

• Journal of KIISE:Computer Systems and Theory
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• v.36 no.4
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• pp.274-282
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• 2009

Various location tracking sensors; such as GPS, INS, radar, and optical equipment; are used for tracking moving targets. In order to effectively track moving targets, it is necessary to develop an effective fusion method for these heterogeneous devices. There have been studies in which the estimated values of each sensors were regarded as different models and fused together, considering the different error characteristics of the sensors for the improvement of tracking performance using heterogeneous multi-sensor. However, the rate of errors for the estimated values of other sensors has increased, in that there has been a sharp increase in sensor errors and the attempts to change the estimated sensor values for the Sensor Probability could not be applied in real time. In this study, the Sensor Probability is obtained by comparing the RMSE (Root Mean Square Error) for the difference between the updated and measured values of the Kalman filter for each sensor. The process of substituting the new combined values for the Kalman filter input values for each sensor is excluded. There are improvements in both the real-time application of estimated sensor values, and the tracking performance for the areas in which the sensor performance has rapidly decreased. The proposed algorithm adds the error characteristic of each sensor as a conditional probability value, and ensures greater accuracy by performing the track fusion with the sensors with the most reliable performance. The trajectory of a UAV is generated in an experiment and a performance analysis is conducted with other fusion algorithms.

• Polymer(Korea)
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• v.38 no.2
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• pp.156-163
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• 2014

Hydroxyapatite has osteoconductivity, biocompatibility and noninflammatory, and it has been used clinically as artificial bone. In this study, we prepared hydroxyapatite/poly(lactic-co-glycolic acid) (PLGA) scaffolds using 0, 10, 20, 40 and 60 wt% of hydroxyapatite. We analyzed compressive strength, SEM analysis and FTIR for mechanical property of 3D hydroxyapatite/PLGA scaffolds. For biocompatibility tests, cell proliferation and viability were measured via MTT assay and SEM. We analyzed RT-PCR, FACS, histology (H&E, ED-1) for anti-inflammatory effect. This study showed that hydroxyapatite hybrid scaffolds have low inflammatory reaction compared with the PLGA. This result has a potential for the application of artificial bone graft material.

• New Physics: Sae Mulli
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• v.68 no.12
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• pp.1315-1323
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• 2018

We studied the carbonization due to the annealing condition of waste coffee powder for application as an active anode material for lithium-ion batteries (LIBs). The coffee powder used as an active anode material for LIBs was obtained from coffee beans, not from a coffee shells. The waste coffee powder was dried in air and heat-treated in an $Ar/H_2$ atmosphere to obtain a pore-forming activated carbon powder. The specific capacity of the sample annealed at $700^{\circ}C$ was still 303 mAh/g after 1000 cycles at a current density of 1000 mA/g and with a coulombic efficiency of over 99.5%. The number of pores and the pore size of the waste coffee powder were increased due to chemical treatment with KOH, which had the some effect as an increased specific surface area. The waste coffee powder is considered to be a very promising active anode material because of both its excellent electrochemical properties due to enhanced carrier conduction and its being a cost effective resource for use in LIBs.

• Journal of Microbiology and Biotechnology
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• v.27 no.4
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• pp.718-724
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• 2017

The combination of rabies immunoglobulin (RIG) with a vaccine is currently effective against rabies infections, but improvements are needed. Genetic engineering antibody technology is an attractive approach for developing novel antibodies to replace RIG. In our previous study, a single-chain variable fragment, scFv57R, against rabies virus glycoprotein was constructed. However, its inherent weak stability and short half-life compared with the parent RIG may limit its diagnostic and therapeutic application. Therefore, an acidic tail of synuclein (ATS) derived from the C-terminal acidic tail of human alpha-synuclein protein was fused to the C-terminus of scFv57R in order to help it resist adverse stress and improve the stability and half-life. The tail showed no apparent effect on the preparation procedure and affinity of the protein, nor did it change the neutralizing potency in vitro. In the ELISA test of molecular stability, the ATS fusion form of the protein, scFv57R-ATS, showed an increase in thermal stability and longer half-life in serum than scFv57R. The protection against fatal rabies virus challenge improved after fusing the tail to the scFv, which may be attributed to the improved stability. Thus, the ATS fusion approach presented here is easily implemented and can be used as a new strategy to improve the stability and half-life of engineered antibody proteins for practical applications.

• KSBB Journal
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• v.30 no.6
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• pp.291-295
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• 2015

The limited productivity of natural shell matrix proteins has hampered the investigation of their biochemical properties and practical applications, although biominerals in nature obtained by organic-inorganic assemblies have attractive mechanical and biological properties. Here, we prepared a vector for the expression of a fusion protein of a shell matrix protein from Pinctada fucata (named as GRP_BA) with the GRGDSP residue. The fusion protein of BA-RGD was simply produced in E. coli and purified through sequential steps including the treatment with $CaCl_2$ and EDTA solution for cell membrane washing, mechanical cell disruption and the application of non-ionic surfactant of Triton X-100 for BA-RGD inclusion body washing. The production yield was approximately 60 mg/L, any other protein band was not observed in SDS-PAGE and it was estimated that above 97% endotoxin was removed compared to the endotoxin level of whole cell. This study showed this simple and easy purification approach could be applied to the purification of BA-RGD fusion protein. It is expected that the protein could be utilized for the preparation of biominerals in practical aspects.

• Journal of Biosystems Engineering
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• v.36 no.6
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• pp.491-499
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• 2011

The objective of this study was to develop the export strategic core technologies for IT fusion next generation agricultural machines by the analysis of comprehensive and cooperative systems of industries, universities, and institutes. In order to achieve the objective of this study, an expert panel was formed and operated. The first survey was conducted by the Delphi method. For this the export strategic core technologies were surveyed and analyzed using the questionnaire. Based on the results of the first survey, the second survey was conducted. The questionnaire used for the second survey was designed by results of the first survey. The results of the second survey was analyzed by AHP method. The third survey was conducted based on the second one, and the final results were analyzed and the export strategic core technologies were developed through the expert meeting. The study results showed six export strategic core technologies as the followings : 1) environment-friendly engine technology for high performance 2) high performance/high efficiency power transmission system technology 3) development of measurement system technology for safety of agricultural products 4) field application of sensor networks 5) large size combine development technology for high performance 6) quality evaluation technology for agricultural products.

• Tribology and Lubricants
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• v.36 no.1
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• pp.47-54
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• 2020

In this study, the effects of ultrasonic nanocrystal surface modification (UNSM) treatment at room and high temperatures (RT and HT of 400℃) on friction and wear behavior of Ti-6Al-4V alloy prepared by selective laser melting (SLM) were investigated. The objective of this study is to improve the mechanical properties and frictional behavior of Ti-6Al-4V alloy by UNSM treatment. Dry friction and wear tests were conducted using a ball-on-disk method at RT with a bearing steel as the counter ball. Due to the high HT and UNSM treatment, the surface hardness tended to increase and surface roughness tended to reduce. X-ray diffraction (XRD) analysis showed that nanocrystallization structure and compressive residual stress were formed at the surface layer after UNSM treatment at both RT and HT. After UNSM treatment, it was observed that the wear rate was reduced by about 6% for the specimen treated at RT and a 28% reduction for the specimen treated at HT in comparison with the untreated one. Based on scanning electron microscope (SEM) images showed that the damage caused by fatigue wear occurred in the wear track of the heat-treated specimen, and it is believed to be the cause of the highest wear rate. Mechanical properties and wear resistance of Ti-6Al-4V alloy were improved and prospect of industrial application was confirmed. Further research is still required to improve the characteristics of SLM Ti-6Al-4V alloy to the level of wrought Ti-6Al-4V alloy.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.40 no.4
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• pp.266-274
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• 2003

Distance Fourier descriptors of local target boundary and feature information fusion using multiple MLPs (Multilayer perceptrons) are proposed. They are used to identify nonoccluded and partially occluded targets in natural FLIR (forward-looking infrared) images. After segmenting a target, radial Fourier descriptors as global shape features are defined from the target boundary. A target boundary is partitioned into four local boundaries to extract local shape features. In a local boundary, a distance function is defined from boundary points and a line between two extreme points. Distance Fourier descriptors as local shape features are defined by using distance function. One global feature vector and four local feature vectors are used as input data for multiple MLPs to determine final identification result of the target. In the experiments, we show that the proposed method is superior to the traditional feature sets with respect to the identification performance.

• Corrosion Science and Technology
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• v.2 no.4
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• pp.202-206
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• 2003

Fusion Bonded Epoxy(FBE) systems have been widely used to protect pipelines for over 30 years. Numerous attempts have so far been made to improve the properties of FBE coatings such as chemical resistance, adhesion, water resistance, cathodic disbondment resistance, impact resistance, and flexibility to protect pipelines at a wet and a high temperature condition. But these attempts have not been successful in reducing some weakness, for instance, in pipeline operating at high temperature due to poor hot water resistance and cathodic protection. The purpose here is to build a basis for getting better corrosion resistance of FBE systems. Cresol-novolac epoxy coating systems were studied compared to bisphenol A type epoxy systems. After the immersion of the film in water at a high temperature for a long period, good adhesion to metal substrate and excellent cathodic disbond resistance were observed in the cresol-novolac epoxy resin systems. It is well known that the adhesion of organic coatings to metal substrate might be decreased due to the disruption of a chemical bond across the film and metal interface induced by water molecules. A high crosslinking density might decrease water permeability and improve cathodic disbonding protection in the coatings. Other factors are studied to understand anti-corrosion mechanism of Cresol-novolac epoxy coatings. In addition, the water absorption rate and the effect of cure temperature on the adhesion and cathodic disbonding resistance ofthe films were studied in different epoxy coatings and the effect of substrate was evaluated. The results of field application are proved that the Cresol-novolac epoxy coating system developed recently is one of the most suitable coatings for protection of pipelines.