• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.8
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• pp.3657-3682
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• 2018

This paper presents a Bluetooth and pedestrian dead reckoning (PDR)-based indoor fusion localization approach (BtPDR) using smartphones. A Bluetooth and PDR-based indoor fusion localization approach can localize the initial position of a smartphone with the received signal strength (RSS) of Bluetooth. While a smartphone is moving, BtPDR can track its position by fusing the localization results of PDR and Bluetooth RSS. In addition, BtPDR can adaptively modify the parameters of PDR. The contributions of BtPDR include: a Bluetooth RSS-based Probabilistic Voting (BRPV) localization mechanism, a probabilistic voting-based Bluetooth RSS and PDR fusion method, and a heuristic search approach for reducing the complexity of BRPV. The experiment results in a real scene show that the average positioning error is < 2m, which is considered adequate for indoor location-based service applications. Moreover, compared to the traditional PDR method, BtPDR improves the location accuracy by 42.6%, on average. Compared to state-of-the-art Wireless Local Area Network (WLAN) fingerprint + PDR-based fusion indoor localization approaches, BtPDR has better positioning accuracy and does not need the same offline workload as a fingerprint algorithm.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.5
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• pp.1516-1539
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• 2022

This article shows a set of physical information fusion IoT systems that we designed for smart buildings. Its essence is a computer system that combines physical quantities in buildings with quantitative analysis and control. In the part of the Internet of Things, its mechanism is controlled by a monitoring system based on sensor networks and computer-based algorithms. Based on the design idea of the agent, we have realized human-machine interaction (HMI) and machine-machine interaction (MMI). Among them, HMI is realized through human-machine interaction, while MMI is realized through embedded computing, sensors, controllers, and execution. Device and wireless communication network. This article mainly focuses on the function of wireless sensor networks and MMI in environmental monitoring. This function plays a fundamental role in building security, environmental control, HVAC, and other smart building control systems. The article not only discusses various network applications and their implementation based on agent design but also demonstrates our collaborative information fusion strategy. This strategy can provide a stable incentive method for the system through collaborative information fusion when the sensor system is unstable in the physical measurements, thereby preventing system jitter and unstable response caused by uncertain disturbances and environmental factors. This article also gives the results of the system test. The results show that through the CPS interaction of HMI and MMI, the intelligent building IoT system can achieve comprehensive monitoring, thereby providing support and expansion for advanced automation management.

• The Korean Journal of Zoology
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• v.36 no.3
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• pp.433-438
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• 1993

In the previous paper (Choi et al., 1992), we found that a large but transient elevation in intracellular cGMP levels occur concomitant with the myoblast fusion. To establish the physiological significance of the elevation of cGMP levels, the change in guanylate cyclase activity dudng myoblast fusion and the correlation hetween various chemicals that may affect guanylate cyclase adivity and myoblast fusion were examined. Sodium nitroprusside, a nitric oxide-forming compound, induced a precocious fusion and increased guanylate cyclase activity compared to the control. Furthermore, L-NG-monomethyl arginine, specific inhibitor of L-arginine: nitric oxide synthase, inhibited the cell fusion in a dose-dependent manner, without affecting biochemical differentiation. On the basis of our present findings, we propose that the onset of myoblast fusion is somehow correlated with the rise in cellular cGMP levels that is regulated by the activation or inhibItIon of soluble guanylate cyclase, via as yet undefined mechanism but possibly through L-arginine: nitric oxide pathway.

• Journal of Korean Neurosurgical Society
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• v.46 no.1
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• pp.65-67
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• 2009

The authors report two cases of spontaneous regression of disc herniation at the level adjacent to the anterior lumbar interbody fusion (ALIF) level. This phenomenon may be due to the increased tension on the posterior longitudinal ligament (PLL) by appropriate restoration of the disc height and lumbar lordosis, which is a mechanism similar to ligamentotaxis applied to the thoracolumbar burst fracture.

• Microbiology and Biotechnology Letters
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• v.23 no.6
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• pp.784-788
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• 1995

The lambda Integrase (Int) carries out site-specific recombination between the two partner DNA sequences, attachment P (attP) and attachment B (attB). In order to study the recombination mechanism, a large quantity of pure integrase is required. Then, we constructed an int gene inserted recombinant plasmid (pNYL3) by using the pQE31 HIS-Tag vector, and produced the fusion protein, 6xHIS-Int from the E. coli TG1 strain carrying the pNYL3 plasmid. The recombinant protein produced was purified by phosphocellulose and Ni$^{++}$-NTA affinity column chromatographies. The result of the in vitro recombination assay using the standard reaction mixture containing 6xHIS-Int and partially purified integration host factor (IHF) showed that the 6xHIS-Int tagged recombination Integrase had the full recombination activity.

• Applied Biological Chemistry
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• v.28 no.1
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• pp.36-47
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• 1985

$HIS_5$ gene of Saccaromyces cerevisiae was cloned into pBR 322 and also into pSH 610 shuttle vector. $HIS_5$ gene was expressed as promoter of lactose operon(lacZ). And $HIS_5-lacZ$ fusion was intergrated into chromosome III of yeast. $HIS_5$ gene in yeast growth was controlled general amino acid control mechanism.

• BMB Reports
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• v.41 no.1
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• pp.11-22
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• 2008

Apoptosis (programmed cell death) is a cellular self-destruction mechanism that is essential for a variety of biological events, such as developmental sculpturing, tissue homeostasis, and the removal of unwanted cells. Mitochondria play a crucial role in regulating cell death. $Ca^{2+}$ has long been recognized as a participant in apoptotic pathways. Mitochondria are known to modulate and synchronize $Ca^{2+}$ signaling. Massive accumulation of $Ca^{2+}$ in the mitochondria leads to apoptosis. The $Ca^{2+}$ dynamics of ER and mitochondria appear to be modulated by the Bcl-2 family proteins, key factors involved in apoptosis. The number and morphology of mitochondria are precisely controlled through mitochondrial fusion and fission process by numerous mitochondria-shaping proteins. Mitochondrial fission accompanies apoptotic cell death and appears to be important for progression of the apoptotic pathway. Here, we highlight and discuss the role of mitochondrial calcium handling and mitochondrial fusion and fission machinery in apoptosis.

• Nuclear Engineering and Technology
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• v.3 no.1
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• pp.33-36
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• 1971

With the use of the significant structure theory of liquid, the fusion criteria has been successfully explained. To test the theory of fusion, the excess volume upon melting has been calculated for some liquids such as simple liquids and fused salts. The results obtained show good agreements between theory and experiment. The theoretical study on the fused salt may be useful to understand the properties and structure of high temperature liquids in the atomic reactor.

• Macromolecular Research
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• v.16 no.6
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• pp.481-488
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• 2008

Apoptosis is a natural cell suicide mechanism to maintain homeostasis. However, many of the diseases encountered today are caused by aberrant apoptosis where excessive apoptosis leads to neurodegenerative disorders, ischemic heart disease, autoimmune disorders, infectious diseases, etc. A variety of antiapoptotic agents have been reported to interfere with the apoptosis pathway. These agents can be potential drug candidates for the treatment or prevention of diseases caused by dysregulated apoptosis. Obviously, world-wide pharmaceutical and biotechnology companies are gearing up to develop antiapoptotic drugs with some products being commercially available. Polymeric drug delivery systems are essential to their success. Recent R&D efforts have focused on the chemical or bioconjugation of antiapoptotic proteins with the protein transduction domain (PTD) for higher cellular uptake with antibodies for specific targeting as well as with polymers to enhance the protein stability and prolonged effect with success observed both in vivo and in vitro. All these different fusion antiapoptotic proteins provide promising results for the treatment of dysregulated apoptosis diseases.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.4
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• pp.1234-1257
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• 2023

In this paper, we propose a framework for multi-focus image fusion called PATN. In our approach, by aggregating deep features extracted based on the U-type Transformer mechanism and shallow features extracted using the PSA module, we make PATN feed both long-range image texture information and focus on local detail information of the image. Meanwhile, the edge-preserving information value of the fused image is enhanced using a dense residual block containing the Sobel gradient operator, and three loss functions are introduced to retain more source image texture information. PATN is compared with 17 more advanced MFIF methods on three datasets to verify the effectiveness and robustness of PATN.