• 동의생리병리학회지
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• 제24권6호
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• pp.1094-1098
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• 2010

With the high prevalence of functional dyspepsia in the world, it was difficult to get objective diagnosis, treatment and assessment for the reason that there were many different symptoms and signs. The purpose of this study is to develop a standard instrument of pattern identification for functional dyspepsia which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 11 oriental division of gastroenterology professors of oriental medical colleges nationwide. The experts discussed developing the instrument, and we also took professional advices by e-mail. We divided the symptoms and signs of functional dyspepsia into 6 pattern identification, such as disharmony of liver and stomach, retention of undigested food, damp-heat in the spleen and stomach, simultaneous occurrence of cold and heat syndromes, deficiency and cold of the spleen and the stomach, and insufficiency of stomach eum. We got the mean weights to each symptom of six pattern identification which had been scored on a 5-point scale ranging from 1 to 5 by the 11 experts. We made out the Korean instrument of the pattern identification composed of 45 questions for functional dyspepsia. Although there are some limitations in our study, the instrument is meaningful and certain worth of its own. We hope to improve the instrument through the further clinical studies and discussions.

• 대한간호학회지
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• 제44권1호
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• pp.75-85
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• 2014

Purpose: The aim of this study was to explore how individual factors, physiologic factors, symptoms, environmental factors, functional status and health perception predict the quality of life (QOL) for older adults with osteoarthritis and to provide guidelines for interventions and strategies to improve QOL in these patients. The conceptual model was based on the Wilson and Cleary's Model. Methods: Data were analyzed using SPSS WIN 20.0 and AMOS 19.0 program. Results: The proposed model was a good fit for the data based on the model fit indices. Based on the constructed model, individual factors, social support, functional status and health perception were founded to have direct effects on QOL. Symptom had a indirect effect on QOL. Social support had a significant effect on QOL, and this model explained 63.6% of the variance in QOL. Conclusion: The results of this study suggest that nursing strategies to increase QOL in this population should contain social support to promote QOL and manage functional limitations and health perception.

• The Journal of Korean Physical Therapy
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• 제29권4호
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• pp.164-168
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• 2017

Purpose: Functional electrical stimulation (FES) is a device that activates the sensorimotor cortex through electrodes attached to the surface of the skin. However, it is difficult to expect positive changes if the recipient is not attentive to the motion. To complement the perceived cognitive limitations of FES, we attempted to investigate the changes of sensorimotor cortex activity by simultaneously providing action observation with FES. Methods: Electroencephalogram was measured in 28 healthy volunteers. Relative band power over the sensorimotor cortex was analyzed and compared in three conditions: during rest, during FES alone, during action observation with FES. Results: The results showed significant differences in each relative band power. Relative alpha power and relative beta power were the lowest by application of FES combined with action observation, while the relative gamma power was the highest. Conclusion: These results suggest that combining FES with observation could be more effective than FES alone in neurorehabilitation.

• 생물정신의학
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• 제22권3호
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• pp.109-112
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• 2015

Since the early 2000s, there has been a continued interest in lie detection using functional magnetic resonance imaging (fMRI) in neuroscience and forensic sciences, as well as in newly emerging fields including neuroethics and neurolaw. Related fMRI studies have revealed converging evidence that brain regions including the prefrontal cortex, anterior cingulate cortex, parietal cortex, and anterior insula are associated with deceptive behavior. However, fMRI-based lie detection has thus far not been generally accepted as evidence in court, as methodological shortcomings, generalizability issues, and ethical and legal concerns are yet to be resolved. In the present review, we aim to illustrate these achievements and limitations of fMRI-based lie detection.

• 한국기계가공학회지
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• 제2권2호
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• pp.14-21
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• 2003

Rapid prototyping(RP) has been used for design verification and proto sample or mold manufacturing. Many RP systems have been introduced into the market during the past 15 years. However, until now, the systems have used mainly for external physical models (mono function), and have the basic but critical limitation of one material on one stage (mono material). To overcome the limitations of mono-material and mono-function of conventional. RP systems, the concept of Functional Phototype Development (FPD) is newly proposed in this paper FPD provides the necessary prototype functions such as mechanical, optical, chemical and electrical properties in order to meet the broad requirements of the industry. The paper illustrates the representative achievements of electronic components such as the multi-layer printed circuit board(MLB). Experimental results demonstrate that FPD has great potential applied to broad industrial uses and that It Will be a powerful tool in the neat future.

• 종양간호연구
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• 제12권1호
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• pp.61-68
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• 2012

Purpose: This study aimed to investigate the influence of resilience and symptom experience on quality of life. Methods: Seventy five patients in an active treatment stage were recruited from 2 hospitals between October and December 2010. A survey including perceived health status, physical functional status, the symptom experience index, resilience, and the functional assessment of cancer therapy-colorectal (FACT-C) was completed. Results: The level of FACT-C was 86.61 (${\pm}18.91$), which was higher than for patients with colostomy, but lower than for patients in a rehabilitation stage. Participants without physical functional limitations showed higher level of both resilience and quality of life. Participants with bad health status showed a lower level of both resilience and quality of life and higher level of symptom experience. The quality of life was related to the level of resilience (${\beta}$=.373), symptom experience (${\beta}$=-.292), and perceived health status (${\beta}$=-3.961). Conclusion: Proactive nursing approaches to manage symptoms and to improve perceived health status would enhance the quality of life of colorectal cancer patients. Furthermore, various strategies to strengthen the level of resilience should be developed.

• 한국의류학회지
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• 제45권5호
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• pp.758-769
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• 2021

Today, functional gloves must allow the wearer to perform many kinds of delicate work while protecting the hands from hazardous materials. In this study, multiple analyses of 3D hand measurements were performed to provide information on the hand size and shape required for the design of functional gloves for adult men. Size and shape characteristics were identified from 19 different hand measurements, and three factors were collected through factor analysis. The aggregated factor score was used to classify men's hand shapes into three types. These types showed different distribution patterns according to age, indicating a significant distribution difference between hand type and age group. Discriminant analysis extracted nine items that highly contributed to determining hand type. However, since the data provided by Size Korea have some limitations in fully representing hand shape, sampling additional types of hand measurements and using consistent conditions and methods are required for more accurate analysis.

• 식품과학과 산업
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• 제53권1호
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• pp.56-68
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• 2020

Recently, chitosan has increased attention in commercial applications in the food industry in terms of its biocompatibility and nontoxicity. In particular, chitosan has been used as a good hosting material for producing nanoparticles due to its unique property of ionic gelation. Chitosan has disadvantages such as low solubility at physiological pH, causing the metabolism of core material in the intestine and gastric juice. To overcome these limitations, various chitosan derivatives such as carboxylated, thiolated, and acylated chitosan have been studied. This review focuses on the changes in the physicochemical properties of chitosan nanoparticles with the introduction of hydrophobic groups, the application of functional nanocapsules as coatings, and their applicability in the food sector. The physicochemical modification of chitosan is expected to be an attractive research field for the development of chitosan applications for food as well as for improving bioavailability in functional food.

• 한국게임학회 논문지
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• 제8권4호
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• pp.75-85
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• 2008

UCC(User Created Contents) 사이트가 활성화되면서 제작 가능한 콘텐츠 종류가 다양해졌다. 제작 가능한 콘텐츠 중에서 UCG(User Created Game)는 사용자가 직접 제작하고 공유하는 게임이다. UCG의 제작 방법은 사용자의 숙련도에 따라서 두 가지로 분류해 볼 수 있다. 첫 번째, 저작도구를 사용하는 방법은 게임 제작에 익숙하지 않은 초보 사용자에게 적합하지만 사용방법이 쉬워지면서 기능이 제약적이다. 두 번째, 프로그램 언어를 이용한 개발은 게임 제작에 익숙한 고급 사용자에게 적합하지만 개발기간이 길어진다. 이 논문에서는 스크립트를 사용해서 초보 사용자에게 적합한 저작도구의 기능을 확장하는 방법을 제안한다. 그리고 제안한 저작도구는 프로그램 소스를 생성하기 때문에 고급 사용자는 제공하지 않는 기능만 추가 구현해서 개발 기간을 단축한다. 제안한 방법의 UCG 제작 과정을 검증하기 위해서 게임 제작에 필요한 GUI, 스크립트 생성 기능과 프로그램 소스 생성 기능을 포함하는 프레임워크를 설계한다. 그리고 설계한 게임 저작도구를 구현해서 개발된 게임 제작 사례를 보임으로써 본 연구에서 제안하는 방법을 소개한다.

• Genomics & Informatics
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• 제11권3호
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• pp.149-154
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• 2013

Liver enzyme elevations, as an indicator of liver function, are widely associated with metabolic diseases. Genome-wide population-based association studies have identified a genetic susceptibility to liver enzyme elevations and their related traits; however, the genetic architecture in childhood remains largely unknown. We performed a genome-wide association study to identify new genetic loci for liver enzyme levels in a Korean childhood cohort (n = 484). We observed three novel loci (rs4949718, rs80311637, and rs596406) that were multiply associated with elevated levels of alanine transaminase and aspartate transaminase. Although there are some limitations, including genetic power, additional replication and functional characterization will support the clarity on the genetic contribution that the ST6GALNAC3, ADAMTS9, and CELF2 genes have in childhood liver function.