• Journal of Microbiology and Biotechnology
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• 제15권6호
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• pp.1280-1285
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• 2005

Using the nodY::lacZ fusion system in Bradyrhizobium japonicum USDA 110, 22 flavonoids, which have structurally different features, were tested to define the role of the substituted functional groups as an inducer or inhibitor for the nod gene expression. A functional ,group of 4'-OH on the B-ring and the double bond between 2-C and 3-C on the C ring were required to induce the nod gene expression in B. japonicum USDA 110. In the case of isoflavones, the 4'-methoxyl group, which blocks the open 4'-OH functional group, did not significantly lower inducing activity, as compared with isoflavones with 4'-OH. However, all flavonols tested, which have a 3-OH functional group on the C-ring, did not induce, but inhibited the nod gene expression. Flavone, 7-hydroxyflavone, and kaempferol (5,7,4'-trihydroxyflavonol) at $1\;{\mu}M$ concentration significantly inhibited the nod gene expression induced by 7,4'-dihydroxyflavone. However, 7-hydroxy-4'-methoxyflavone at $1\;{\mu}M$ concentration showed a synergistic effect with genistein and 7,4'-dihydroxyflavone on the induction activity.

• 한국자기공명학회논문지
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• 제24권4호
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• pp.104-116
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• 2020

Fipronil, the phenylpyrazole insecticide, is effective and used in various fields. Especially, fipronil was reliable because it was known to be specific on invertebrate animals than vertebrate animals including mammals. However, fipronil had potential risks that affect vertebrate animals as it blocks the gamma-aminobutyric acid (GABA) receptors that also exists in vertebrates as well as invertebrates. Therefore, it was necessary that harmful effects of fipronil on vertebrates are clarified. For this purpose, the zebrafish (Danio rerio) were used on behalf of vertebrate animals in present study. The zebrafish were exposed to 5 ㎍/L, 25 ㎍/L, and 50 ㎍/L of fipronil during 12, 24 and 72 hours. To closely observe toxic process, 12 hours and 24 hours of additional time point were set in the exposure test. Nuclear magnetic resonance (NMR)-based metabolomics is an approach to detect metabolic changes in organism resulted from external stimuli. In this study, NMR-based metabolomics showed the metabolic changes in zebrafish caused by fipronil exposure. Metabolic analysis revealed that fipronil interfered with energy metabolism and decreased the antioxidant ability in zebrafish. Antioxidant ability decline was remarkable at high exposure concentration. In addition, metabolic analysis results over time suggested that reactions for alleviating the excessive nerve excitation occurred in zebrafish after fipronil exposure. Through this study, it was elucidated that the adverse effects of fipronil on vertebrate animals are evident. The risk of fipronil on vertebrates can be no longer ignored. Moreover, this study has a meaning of practically necessary research for organism by examining the effects of fipronil at low concentrations existed in real environment.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 추계종합학술대회 논문집
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• pp.759-762
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• 1998

In this paper, a SL-DCVSL (static latched differential cascode voltage switch logic) circuit for the asynchronous pipeline is proposed. The proposed SL-DCVSL circuit is a slightly modified version of the DCVSL circuit, and used to improve the storage capability of the precharged functional blocks. The proposed SL-DCVSL has more robust storage characteristics compared to the conventional LDCVSL (latched DCVSL〔2〕). The operation of the proposed circuit is verified by simulating the asynchronous FIFO (First-In First-Out) structure.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2000년도 춘계학술발표대회
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• pp.579-582
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• 2000

Enantiomerically pure hydroxycarboxylic acids have great potential as chiral building blocks in fine chemicals due to their easily modificable two functional groups. Microbial polyhydroxyalkanoates (PHAs) can have more than one hundred of hydroxycarboxylic acids as monomeric constituents by growing cells under various conditions. All of the monomeric constituents are enantiomerically pure in (R)-conformation if there is a chiral center. Therefore, efficient production of enantiomerically pure hydroxycarboxylic acids by degrading PHAs is possible. In this presentation, we report on the development of a novel method for the preparation of (R)-hydroxybutyric acid by in vivo depolymerization of Polyhydroxybutyrae.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.231.2-232
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• 2002

The synthesis of chiral 1,2-amino alcohols has been an area of intense study in the synthetic and industrial fields, because of their important roles in organic synthesis as fundamental building blocks and their occurrence in a number of natural products. drugs. and chiral auxiliaries or ligands. General methods for the synthesis of these compounds can be divided into two large categories: functional group transformations and the C-C or the C-N bond formations. (omitted)

• 전기학회논문지P
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• 제51권3호
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• pp.142-148
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• 2002

Considerable progress has been made in organic photorefractive materials, since the first observation of photorefractive phenomena from organic materials. Within recent years, a large number of organic photorefractive materials, especially amorphous materials, have been developed based on polymeric composites, fully functional polymers and the multi-functional chromophore approach. Among these organic photorefractive materials, some of them containing carbazole components as a charge transporting function have been demonstrated to exhibit high performance photorefractive effects. The carbazole building blocks with charge transporting function or multifunctions play a very important role in photorefraction. In this paper, it confirmed that acceptor-substituted carbazoles show the multifunctionality both of photoconductivity and electro-optic(EO) activity and photorefractive materials newly can be developed with acceptor-substituted carbazoles.

• 전자공학회논문지B
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• 제30B권4호
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• pp.85-91
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• 1993

In this paper, we propose the test pattern generation algorithm of the embedded faulty MUX for the prevention of misdiagnosis of digital systems. When the system is partitioned with a large number of functional blocks, if the faults are exsisted in a embedded MUX then it can not diagnose the wanted observation of functional block. The proposed test pattern generstion algorithm can apply the MUXs that designd 2-level and multi-level both. Fault coverage becomes 100% and so it is no necessary of the additional fault simulation and the proposed algorithm that have the regulary and easily generated 2d test patterns. And we confirmed that the reduction of test cost becomes 85%, compared with the conventional segmentation testing scheme.

• 대한가정학회지
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• 제34권2호
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• pp.43-55
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• 1996

The purpose of this study was to investigate the slacks pattern making on the movement-fitness of the knee region. The experimental items were divided into the lower limb movement (M1~M5) and slacks pattern designs (4 : basic pattern, in-pleats, side-pleats, seam-line increase). This study was done by clothing pressure test, sensory evaluation test and the difference shape-transformation of wearing-slacks. The summarized finding resulted from experiments and investigation are suggested as follows ; First, the clothing pressure test showed that the order of clothing pressure in the movement was the rabbit leap movement (M3), the sit on knees (M4), the nobleman sitting (M5), the sit on chair (M2) from the highest to the lowest. In the comparison of clothing pressure tested by blocks of lower-limb, center front knee region shows the highest of 300g/cm2. In it by constructional methods, the clothing pressure of in-pleats, side-pleats methods shows lower than basic pattern, hem-line increase methods. Also in comparison of the two methods, in-pleats method shows lower than side-pleats method. Second, by the sensory evaluation test based on the lower-limb movements and constructional methods of slacks, it was found that the functional factor score of the rabbit leap movement was also the waist, hip, knee region was the lowest in all blocks. And in the comparison of constructional methods, in-pleats method was the highest in all methods. Third, in consideration of the difference in the shape-transformation of wearing-slacks on the movement-fitness, pleats pattern design methods showed that the ratio of shape-transformation was lower than basic on seam-line increase methods. But the difference of the side-pleats and in-pleats methods was litle. According to these investigation, the slacks pattern making caused by movement-fitness on the knee region, in-pleats design method was the functional slacks pattern.

• 한국문헌정보학회지
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• 제30권1호
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• pp.3-18
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• 1996

본고는 전거용 MARC 포맷의 3요소로 일컬어지는 구조와, 내용표지법, 레코드의 내용에 대해 UNIMARC와 USMARC, KORMARC를 중심으로 비교 분석하였다. 레코드의 구조와 내용표지 법은 ISO 2709를 채택하고 있으므로 대부분 서지용포맷과 동일하다. 다만 데이터필드의 구조와 블록구분은 USMARC와 KORMARC가 전통적인 목록의 전거카드형식을 따르고 있고 UNLMARC는 GARE의 일반적 구조를 따르고 있어, 차이를 보이고 있다. 고정길이필드의 레코드의 내용에는 USMARC와 KORMARC의 경우에 표목의 선정과 상태 및 범위,총서에 관련된 사항이 많이 포함되어 있고 UNIMARC에는 국제적 상호교환에 관련된 요소들이 추가되어 있다. 가변길이필드의 비교분석을 통하여 KORMARC의 한자데이터 처리와 관련하여 별도의 서브필드$(\blacktriangledown\;j)$를 설정할 것과, 총서에 대한 청구기호와는 별도의 분류기호필드를 설정할 것을 제안하였다.

• 한국문헌정보학회지
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• 제33권3호
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• pp.63-86
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• 1999

본고는 소장데이터용 MARC 포맷의 일반적 특성과 개발현황에 대해 살펴보고, 아울러 MARC 포맷의 3요소로 일컬어지는 구조와, 내용표지법, 레코드의 내용을 이미 개발된 USMARC과 KORMARC 포맷을 중심으로 분석하였다. 레코드의 구조와 내용표지법은 서지용 및 전거용포맷과 대부분 동일하다. 데이터필드는 기본적으로 기능별블록으로 구분되어 있으나, 현재는 0XX, 5XX, 8XX 필드만이 사용되고 있다. 008 필드의 레코드 내용에는 수서와 보유정책 등 자료의 소장에 관련된 요소들이 추가되어 있다. 가변길이필드의 내용은 번호와 코드, 주기, 소재와 접근, 소장데이터 필드 등으로 구성되며, 특히 소장데이터필드는 다시 캡션과 패턴, 권호와 연대, 문장형식소장정보 자료정보 등의 필드로 구성된다. 본고에서는 각 필드별로 그 내용을 구체적으로 분석하고 있다.