• Clinical and Experimental Pediatrics
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• v.62 no.2
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• pp.55-61
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• 2019

Purpose: Myotonic dystrophy, also known as dystrophia myotonica (DM), is an autosomal dominant disorder with 2 genetically distinct forms. DM type 1 (DM1) is the more common form and is caused by abnormal expansion of cytosine/thymine/guanine (CTG) repeats in the DM protein kinase (DMPK ) gene. Our study aimed to determine whether the age of onset is correlated with CTG repeat length in a population of pediatric patients with DM1. Methods: We retrospectively identified 30 pediatric patients with DM1 that underwent DMPK testing, of which the clinical data of 17 was sufficient. The cohort was divided into 2 subgroups based on the clinical phenotype (congenital-onset vs. late-onset) and number of CTG repeats (<1,000 vs. ${\geq}1,000$). Results: We found no significant difference between the age of onset and CTG repeat length in our pediatric patient population. Based on clinical subgrouping, we found that the congenital-onset subgroup was statistically different with respect to several variables, including prematurity, rate of admission to neonatal intensive care unit, need for respiratory support at birth, hypotonia, dysphagia, ventilator dependence, and functional status on last visit, compared to the late-onset subgroup. Based on genetic subgrouping, we found a single variable (poor feeding in neonate) that was significantly different in the large CTG subgroup than that in the small CTG subgroup. Conclusion: Clinical variables exhibiting statistically significant differences between the subgroups should be focused on prognosis and designing tailored management approaches for the patients; our findings will contribute to achieve this important goal for treating patients with DM1.

• Journal of Korean Neurosurgical Society
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• v.62 no.6
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• pp.700-711
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• 2019

Objective : The treatment of multiple thoracolumbar spine fractures according to fracture continuity has rarely been reported. Herein we evaluate the clinical features and outcomes of multiple thoracolumbar fractures depending on continuous or noncontinuous status. Methods : From January 2010 to January 2016, 48 patients with acute thoracic and lumbar multiple fractures who underwent posterior fusion surgery were evaluated. Patients were divided into two groups (group A : continuous; group B : noncontinuous). We investigated the causes of the injuries, the locations of the injuries, the range of fusion levels, and the functional outcomes based on the patients' general characteristics. Results : A total of 48 patients were enrolled (group A : 25 patients; group B : 23 patients). Both groups had similar pre-surgical clinical and radiologic features. The fusion level included three segments (group A : 4; group B : 5) or four segments (group A : 19; group B : 5). Group B required more instrumented segments than did group A. Group A scored 23.5 and group B scored 33.4 on the Korean Oswestry Disability Index (KODI) at the time of last follow-up. In both groups, longer fusion was associated with worse KODI score. Conclusion : In this study, due to the assumption of similar initial clinical and radiologic features in both group, the mechanism of multiple fractures is presumed to be the same between continuous and noncontinuous fractures. The noncontinuous fracture group had worse KODI scores in long-term follow-up, thought to be due to long fusion level. Therefore, we recommend minimizing the number of segments that are fused in multiple thoracolumbar and lumbar fractures when decompression is not necessary.

• Journal of the Korean Applied Science and Technology
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• v.36 no.1
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• pp.189-199
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• 2019

The aim of this study was to investigate the effect of combine exercise on the fall injury related index and myokine in elderly women. Sarcopenia leads to a loss of strength, alter on to a decreased functional status, impaired mobility, a higher risk of falls, and eventually an increased risk of mortality. Aerobic exercise characterized by rhythmic and repetitive movements of large muscles, for sustained periods that depends primarily on the use of oxygen to meet energy demands through aerobic metabolism, and that is structured and intended to generate improvements in cardiopulmonary fitness, body composition, and cardiorespiratory health. Resistance training has performance in the elderly. As combined exercise therapy can be used to enhance muscle functions and cardiopulmonary functions, it is being highlighted as an effective health management methods for the aged. The myokine has been regarded an important factor of exercise how muscle communicate adipose tissue, bone and muscle to exert beneficial effects at the whole body level.

• Journal of Fashion Business
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• v.23 no.2
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• pp.110-123
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• 2019

This study aims to investigate the color characteristics of female fitnesswear by analyzing the status of color usage and color arrangement method of each item of female fitnesswear of sports brands. This study targeted eight global total sportswear brands. A total of 2956 colors of female sportswear were collected and analyzed from the homepage of each brand. As a result of analyzing the color of fitnesswear, first, the overall color of the fitnesswear showed high distribution centered on PB, Bk and R of low color tone, such as p and dkg. Moreover, bright tone colors were added for vitality and functional image of sports. Second, as a result of analyzing the color of each item, commonly, the PB, Bk and R had large proportions. Third, as a result of analyzing 2-color arrangements of fitnesswear, color arrangements including achromatic color had overwhelmingly higher frequency than color arrangements that had only chromatic colors. This shows that the color arrangement using achromatic color is important and has a higher preference. Fourth, as a result of extracting the representative color arrangement as color chip and comparing, the 2-color arrangement of female fitnesswear had the characteristics of the color arrangement of large area main color and small amounts of emphasized color centered on achromatic colors of Bk and W. This study is meaningful that it can be utilized as basic data for color planning of fitnesswear brands by subdividing female fitnesswear into 4 items and analyzing the color-tone and arrangement.

• Journal of Digital Convergence
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• v.17 no.5
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• pp.327-332
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• 2019

The purpose of this study is to derive the differentiation and improvement measures of Kakao T through a usability evaluation centered on the service. In-depth interviews were conducted by first identifying the status of the mobility O2O service and reconfiguring the usability principles of the Honeycomb model, focusing on the functions and interfaces. First, there are problems driven from the imbalance in supply and demand as a mobility service, but it is likely to be improved through the addition of future features, carpooling. Second, problems were elicited for not recognizing the need for incorporated functions of Kakao T in the presence of existing functional-specific applications. Improvements derived based on this study are expected to help increase the convenience of users of mobility O2O services.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.49-58
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• 2021

Purpose : This study investigates the effects of the application of traditional occupational therapy and the korean computerized cognition training system on the cognitive function and performance of daily activities of stroke patients with cognitive impairment. Methods : From inpatients referred for rehabilitation treatment at L Rehabilitation Hospital located in Busan, 20 patients diagnosed with stroke from April 05. 2021 to May 02. 2021 (study period) were selected, They were divided into two, an experimental group consisting of 10 subjects who underwent a computerized cognitive rehabilitation program and traditional occupational therapy in combination and a control group of 10 subjects who underwent traditional occupational therapy alone. In order to measure the cognitive function of the subjects before the intervention, two assessment tests were conducted: a Neurobehavioral Cognitive Status Examination (NCSE), which evaluates stroke-related cognitive ability, and a Functional Independence Measure (FIM) test, which evaluates life activities. Then, both groups received a total of 20 training sessions at 30 minutes per session, five times a week for four weeks. Results : A statistically significant difference was found in cognitive function between before and after the cognitive training for both the experimental group and the control group. For the FIM scores, statistically significant differences were observed after intervention in the categories of handling personal matters and social cognition, and in the total score. The average scores of the remaining items also improved. Conclusion : The results of this study showed that both the computerized cognition rehabilitation program and the traditional occupational therapy had a positive effect on the improvement of cognitive function in stroke patients.

• Applied Chemistry for Engineering
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• v.32 no.2
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• pp.132-138
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• 2021

This review investigated the types of physiologically active substances isolated and extracted from Pinus densiflora and koraiensis native to Republic of Korea, and the current status of research on their effectiveness and industrial use. They contain various bioactive substances including essential oils, polyphenols, resins, and stilbene derivatives. In recent, physiological activities such as antioxidant, anti-inflammatory, antibacterial, cataract prevention, and neuroprotection from extracts of Pinus densiflora and koraiensis have been identified by domestic researchers. The extracts have been used in different industrial fields like food, health functional foods, cosmetics, and household goods, but the high proportion of them is industrially made from exotic species. Therefore, various studies on industrial applicability are needed due to the lack of cases in which the activity is applied to actual products, with respect to the effects that have been scientifically recognized.

• Journal of Digital Convergence
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• v.19 no.1
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• pp.187-198
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• 2021

This study aims to understand the current status of the use of IoT-based products and services from the perspective of consumers and analyze the role and consumption value of each service-generated from the products and services. Their features and generated consumption value have been identified The decision-making process was divided into based on three stages (pre-purchase, purchase, and post-purchase) stages, and IoT services were classified in stages. In the pre-purchase stage, the IoT service provides information and alternatives, and is used for interaction and automatic payment systems in the purchasing stage. In the post-purchase stage, repetitive purchases are encouraged and after-sale services are provided. Throughout the decision-making process, smart retai application and servicel provides epistemic and functional value. In addition, it provides conditional and social value in the pre-purchase stage, and conditional value in the post-purchase stage. This study aims to provideprovides marketers and retailers an insight advice for the enhanced satisfaction of consumersimproving the satisfaction of consumers and the development of smart retail by examining the consumer-centered consumption value.

• Journal of the Korea Convergence Society
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• v.12 no.1
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• pp.163-170
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• 2021

Smart-textronics technology which enables functional textiles has recently been applied in various fields such as smart clothes, smart home and smart health care, and a variety of smart-textronics products have been developed. In this context, the smart-textronics product development process is proposed based on the systematic participatory design method in this paper. The proposed method consists of two phases: in-depth interviews and analyzing. In the phase of in-depth interviews, participants are asked to create journey maps that include activities, pain points and emotional status and to generate solution ideas with sketches and simple prototypes. In the analyzing phase, design researchers investigate the participants' journey maps, and create personas by identifying critical characteristics with the behavior pattern analysis. Then, each persona's needs are linked with value elements of the E3 value framework. Finally, pre-survey was conducted to identify smart-textronics market and a smart sofa design is proceeded as the case study to show the applicability of the proposed method.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.6
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• pp.93-103
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• 2018

In the past, the rooftop was a place where a water tank was to be installed, and a space of secretion and concealment such as a warehouse exposed in the air. It was because it was judged to hinder the beauty of a city as a whole without having any functional value per se. However, the roof portion is increasingly being utilized for a space such as a cafe, a pub, and a lounge as the rooftop is highly recognized as a place for leisure activities other than an idle space in modern times. Nonetheless, there are no detailed ordinances and criteria corresponding to such circumstances. For example, in case of the rooftop space, the building code applied to the rooftop space is a legal system when the rooftop was an idle space in the past though people have now accessed more increasingly to the rooftop than in the past. This study investigated the definition on the rooftop space evolved in accordance with the change of the rooftop space and the related legal system in Korea, and conducted a survey for the purpose of performing the field investigation for the analysis of physical status in 117 spaces that form the rooftop space in the rooftop of small-scale commercial facilities with 2 stories through 4 stories in Korea and analyze the recognition of users and analyzing the recognition of users. We analyzed the problems in the rooftop space through analysis of derived data, and suggested improvement plans.