• 제목/요약/키워드: Functional Status

검색결과 1,119건 처리시간 0.032초

흰쥐에서 민들레 추출물이 사염화탄소에 의한 산화적 스트레스의 경감기전 (Taraxacum Mongolicum H. Suppress Hepatoprotective Activity by Increasing Liver Antioxidant Enzyme in Carbon Tetrachloride($CCl_4$)-induced Hepatotoxicity in Rats)

  • 김성훈;최종원
    • 동의생리병리학회지
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    • 제24권3호
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    • pp.439-445
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    • 2010
  • Pretreatment with Taraxacum Mongolicum H(TMH) prior to the administration of on $CCl_4$ significantly prevented the increased serum enzymatic activity of aminotransferase(ALT, AST), gamma-glutamyl transpeptidase(GGT) and bilirubin concentration in dose-dependent manner. In addition, pretreatment with TMH also significantly restored the elevation of hepatic malondialdehyde formation and the depletion of reduced glutathione content in the liver $CCl_4$-intoxicated rats. The restoration of microsomal aniline hydroxylase and aminopyrine N-demethylase activities indicated the improvement in functional status of endoplasmic reticulum. $CCl_4$-induced hepatotoxicity was also essentially prevented, as indicated by a liver histopathologic study. TMH showed antioxidant effects in $FeCl_2$-ascorbate-induced lipid peroxidation in rat liver homogenate and in superoxide radical scavenging activity. Our results suggest that the protective effect of TMH against $CCl_4$-induced hepatotoxicity possibly involve mechanisms related to its ability to block p450-mediated $CCl_4$ bioactivation and free radical scavenging effects.

승모판막 수술에 따른 심전도 변화 (The Study on Electrocardiographic Changes after Mitral Valvular Replacement)

  • 여승동;임승평
    • Journal of Chest Surgery
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    • 제24권4호
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    • pp.421-427
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    • 1991
  • Atrial fibrillation[Af] is closely related to thrombus in left atrium, systemic embolism, and loss of the contribution of atrial contraction to cardiac output. Therefore maintenance of sinus rhythm[SR] is undoubtedly hemodynamically superior to Af in the clinical course of mitral valvular disease especially in the unstable period immediately after surgery. In this article, the conversion rate and the factors influencing the conversion of Af to SR after surgery were studied. Ninety-three patients with mitral valvular replacement at Chungnam National University Hospital were analysed with electrocardiography before and after surgery during the period from June 1985 to June 1990. Eighty patients presented Af before surgery. Twenty-four[30Yo] of the patients were converted to SR[A group] and fifty six presented continuous Af after surgery[B group]. The duration of preoperative Af, preoperative left atrial dimension[LAD], preoperative functional status[NYHA classification] and cardiothoracic[CT] ratio were factors influencing the conversion of Af to SR after surgery. The mean preoperative duration of Af was 3.5$\pm$2.6yr in group A and 7.6$\pm$4.9yr in group B. The mean preoperative LAD was 53. 7$\pm$9.4mm in group A and 62.5$\pm$11.2mm in group B. Before surgery, eleven patients[46%] were belong to NYHA class I, II in group A and eight[14%] in group B. The preoperative CT ratio was 62$\pm$6% in group A and 69$\pm$8% in group B.

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호흡운동이 호흡근 활성도 및 흉곽용적에 미치는 영향 (Effect of Breathing Exercises Improves Respiratory Muscle Activity and Chest Expansion)

  • 하미숙;남건우
    • 대한물리치료과학회지
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    • 제21권1호
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    • pp.79-84
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    • 2014
  • Background : This study is for respiratory muscle activity and chest expansion through practice abdominal breathing exercises. Methods : The subjects were consisted normal 30 persons(15 males and 15 females). The control group to 15 people to compare group and 15 people for the abdominal breathing exercise group through lip retraction movement of the therapist with the resistance of mediated abdominal breathing exercises. For 8 weeks EMG was used to know the changes in respiratory muscle. We also found out the changes in chest expansion. And the t-test was conducted to analyze among the compared group, the abdominal breathing group the differences between before and after the experiment. Results : On the changes in respiratory muscle muscular activity in the transverse abdominis have shown significant results(p<.05), and the change in chest expansion was no significant(p>.05). Conclusion : Various breathing exercises in future research on intervention programs can be studied to promote the public if the functional status is considered to be of much help.

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통제어휘 표준의 변화 및 시사점에 대한 연구 (A Study on the Changes in Standards Related to Controlled Vocabulary and Their Implications)

  • 김성원;김정우
    • 한국문헌정보학회지
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    • 제45권1호
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    • pp.211-232
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    • 2011
  • 대표적인 통제어휘인 시소러스는 지난 50년간 정보의 색인과 검색을 위한 도구로 널리 활용되어 왔다. 이러한 흐름에 발 맞추어 다양한 주제분야에서의 시소러스 개발을 위한 지침을 제공하기 위해 국제표준 및 국가표준이 개발되었으며, 최근 들어 시소러스 관련 표준의 개정작업이 활발히 이루어지고 있다. 이러한 시소러스 관련 표준으로 ISO 25964와 BS 8723이 대표적인 사례이다. 본고에서는 이러한 표준의 개정 현황을 살펴보고 변화된 내용과 그 시사점을 도출하여 보았다. 이러한 고찰 결과를 기반으로 오늘날의 새로운 정보환경 아래에서 시소러스가 제공할 수 있는 새로운 기능과 그 기능을 수행하기 위해 필요한 요소들을 제시하였다.

청소년들의 치과 공포감이 구강건강 삶의 질에 미치는 영향 (Impact of dental fear on oral health related quality of life in teenagers)

  • 이혜경
    • 한국치위생학회지
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    • 제16권5호
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    • pp.759-766
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    • 2016
  • Objectives: The purpose of the study was to investigate the impact of dental fear on the oral health related quality of life in teenagers. Methods: A self-reported questionnaire by Likert 5 point scale was completed by 900 high school students in J area from March 10 to April 20, 2014. The questionnaire consisted of general characteristics of the subjects, dental fear survey, and oral health related quality of life. Data were analyzed by t-test and One-way ANOVA using SPSS 12.0 program. Results: Oral symptoms had no significant differences in mother's education and family economic status. Emotional well-being factors had no significant difference in age, religion, school performance, and family economic strength. Dental fear was closely related to emotional well-being, Oral symptoms, social stabilities, functional limit and mental stabilities. Explanation power of the model was 29.1%. Conclusions: It is very important to explain the dental fear procedure to teenagrers before dental surgery and this will enhance the oral health related quality of life in teenagers.

한국판 Western Ontario MacMaster(WOMAC)의 Rasch분석 (Rasch Analysis of the Korean Western Ontario McMaster (KWOMAC): In the Out-Patients Over 65 Years With Osteoarthritis of the Knee)

  • 고은경;이충휘
    • 한국전문물리치료학회지
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    • 제14권1호
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    • pp.82-89
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    • 2007
  • The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a valid and widely used instrument for the assessment of osteoarthritis patients. In this study, data was obtained from the out-patients with painful osteoarthritis of the knee. One hundred-three out-patients were interviewed by physical therapists. In an exploratory way, a Korean version of the KWOMAC was analyzed for unidimensionality, item separation, and item difficulty using the Winsteps programs. Ninety-five patients with osteoarthritis of the knee over 65 years were analyzed for Rash analysis. In the analysis several functional items poorly fit to the model. These items included "heavy domestic duties" and "standing". In the pain domain, one item ("at night while in bed") did not fit the model. In the stiffness domain one item ("after sitting, lying, or resting later in the day") did not fit the model. Although 4 items from the 3 domains (pain, stiffness, function domain) do not fit well, the KWOMAC domains were confirmed by Rasch analysis. Thus the KWOMAC needs to be further examined before it can be used to properly determine the health status of the elderly with OA.

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부산항 재개발 대상지의 개발우선순위 평가 및 개발방안에 관한 연구 (A Study on Evaluation of Development Priority Order & Scheme for Redevelopment Target Area in Pusan Port)

  • 여기태;박창호;김진구
    • 한국항만경제학회지
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    • 제18권1호
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    • pp.61-83
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    • 2002
  • Korea has designated 28 trade ports and 22 coastal ports under the Ports Act. If fishery ports and small inlets are counted, the number amounts to hundreds of ports. However, untimely and inefficient maintenance and repair works face Korean ports with functional loss, decreasing efficiency, and even catastrophe. Thus, further examinations on the maintenance or redevelopment of forts in Korea are urgent. Since the Korean War and the higher economic growth period in the 1970s, Busan Port has developed in a variety of ways, according to the necessity of social conditions at any given time, without any development Philosophy or systematic long-term master plan. As a result, ports and coastal industrial facilities have rushed to gather around the present North Busan Port, which has taken on mixed functions between ports and cities, adversely affecting several of their interactions. To resolve these circumstances, several redevelopment schemes were suggested for centering the old zone in the Busan Port interim. However, comprehensive evaluation and redevelopment schemes combining functions of both ports and cities, and effectively utilizing coastal zones have never been presented. In this respect, this study sets the priority order of the extracted unit project. This study analyzes the existing functions and facilities of Busan Port, extracting facility zones through redevelopment which is certain to fail or to decrease in efficiency. furthermore, this study presents status and development directions of specified redevelopment unit projects of higher priority order, and pursues the integrated plan of efficiency for Busan Port.

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ICT융복합 기술을 이용한 차세대 배전계통 운영 시스템 설계 및 검증 (Design and Verification of Advanced Distribution Management System using Information and Communication Convergence Technology)

  • 김동욱;박영배;추철민;조성호;서인용
    • 디지털산업정보학회논문지
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    • 제15권4호
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    • pp.19-29
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    • 2019
  • Recently, with the rise of environmental issues and the change of government policy (Renewable Energy 3020 Implementation Plan), a large amount of renewable energy such as solar and wind power is connected to the power system, and most of the renewable energy is concentrated in the power distribution network. This causes many problems with the voltage management and the protection coordination of the grid due to the its intermittent power generation. In order to effectively operate the distribution network, it is necessary to deploy more intelligent terminal devices in the field to measure the status of the distribution network and develop various operation functions such as visualization and big data analysis to support the power distribution system operators. In addition, the failover technology must be supported for the non-stop operation of the power distribution system. This paper proposes the system architecture of new power distribution management system to cope with high penetration of renewable energy. To verify the proposed system architecture, the functional unit test and performance measurement were performed.

섬망의 역학 (The Epidemiology of Delirium)

  • 김정란
    • 정신신체의학
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    • 제16권2호
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    • pp.81-86
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    • 2008
  • 섬망은 자연적으로 발생하는 상태는 아니며 더욱이 내인성 질환은 아니다. 그러나, 섬망은 일부 특정인구 집단에서 발생하는 데, 노인 또는 내과적 상태가 악화된 환자들에서 흔히 발생된다. 이것은 체계적인 섬망역학 연구의 제한점으로 작용한다. 일반 인구 집단에서는 그 발생이 상대적으로 적기 때문에 섬망에 대한 많은 역학 연구들은 노인에 집중되었다. 그리고, 연구에 사용된 섬망 평가도구들의 민감도와 특이도도 매우 다양하다. 노령, 남자, 불량한 인지 및 기능 상태, 그리고 알코올 남용이 잘 알려진 섬망의 위험 인자들이다. 저자는 노인, 치매 환자, 고관적 골절 환자, 중환자실 입원 환자, 말기 암 환자, 그리고 뇌졸중 환자에서의 섬마의 역학에 대하여 다루게 될 것이다.

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Clinical Experiences of Transforaminal Balloon Decompression for Patients with Spinal Stenosis

  • Kim, Sung-Hoon;Koh, Won-Uk;Park, Soo-Jin;Choi, Woo-Jong;Suh, Jeong-Hun;Leem, Jeong-Gil;Park, Pyung-Hwan;Shin, Jin-Woo
    • The Korean Journal of Pain
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    • 제25권1호
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    • pp.55-59
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    • 2012
  • Lumbar spinal stenosis is a commonly treated with epidural injections of local anesthetics and corticosteroids, however, these therapies may relieve leg pain for weeks to months but do not influence functional status. Furthermore, the majority of patients report no substantial symptom change over the repeated treatment. Utilizing balloon catheters, we successfully treated with three patients who complained persistent symptoms despite repeated conventional steroid injections. Our results suggest that transforaminal decompression using a balloon catheter may have potential in the nonsurgical treatment of spinal stenosis by modifying the underlying pathophysiology.