• Title/Summary/Keyword: Functional Elements

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Regulation and Function of the Peg3 Imprinted Domain

  • He, Hongzhi;Kim, Joomyeong
    • Genomics & Informatics
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    • v.12 no.3
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    • pp.105-113
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    • 2014
  • A subset of mammalian genes differ functionally between two alleles due to genomic imprinting, and seven such genes (Peg3, Usp29, APeg3, Zfp264, Zim1, Zim2, Zim3) are localized within the 500-kb genomic interval of the human and mouse genomes, constituting the Peg3 imprinted domain. This Peg3 domain shares several features with the other imprinted domains, including an evolutionarily conserved domain structure, along with transcriptional co-regulation through shared cis regulatory elements, as well as functional roles in controlling fetal growth rates and maternal-caring behaviors. The Peg3 domain also displays some unique features, including YY1-mediated regulation of transcription and imprinting; conversion and adaptation of several protein-coding members as ncRNA genes during evolution; and its close connection to human cancers through the potential tumor suppressor functions of Peg3 and Usp29. In this review, we summarize and discuss these features of the Peg3 domain.

In vivo action of RNA G-quadruplex in phloem development

  • Cho, Hyunwoo;Cho, Hyun Seob;Hwang, Ildoo
    • BMB Reports
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    • v.51 no.11
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    • pp.547-548
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    • 2018
  • Phloem network integrates cellular energy status into post-embryonic growth, and development by tight regulation of carbon allocation. Phloem development involves complicated coordination of cell fate determination, cell division, and terminal differentiation into sieve elements (SEs), functional conduit. All of these processes must be tightly coordinated, for optimization of systemic connection between source supplies and sink demands throughout plant life cycle, that has substantial impact on crop productivity. Despite its pivotal role, surprisingly, regulatory mechanisms underlying phloem development have just begun to be explored, and we recently identified a novel translational regulatory network involving RNA G-quadruplex and a zinc-finger protein, JULGI, for phloem development. From this perspective, we further discuss the role of RNA G-quadruplex on post-transcriptional control of phloem regulators, as a potential interface integrating spatial information for asymmetric cell division, and phloem development.

Implementation of Wireless Network simulator considering a User's Call Characteristics (사용자 통화 특성을 고려한 무선 네트워크 시뮬레이터 구현)

  • Yoon, Young Hyun
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.5 no.3
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    • pp.107-115
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    • 2009
  • Traditionally, simulation method is used to test and evaluate the performance of communication protocol or functional elements for mobile communication service. In this paper, wireless network simulator is implemented using the C++ object-oriented programming language. This simulator can simulate wireless data services, like as ad-hoc networks, by considering the user's mobility. In this paper, the simulator includes network traffic model to reflect wireless data service and traffic source model to represent a user's mobility similar to real service environment and traffic characteristics can be reflected on the simulation, and also more accurate simulation results can be got through that. In addition, by using object-oriented techniques, new service feature or environment can be easily added or changed so that the developed mobile communication simulator can reflect the real service environment all the time. This simulator can be used in adjusting the characteristics of wireless data hosts following the mobility of the user, and also can be used in building new wireless ad-hoc network routing protocols.

A Study on the Influence of Airport Environment on Airport Users' Emotions -Focused on Incheon International Airport- (공항 환경이 공항이용객의 감정에 미치는 영향에 관한 연구 -인천국제공항을 중심으로-)

  • Park, Hak-Soon;Kim, Ha-Young;Lee, Jin-Young;Lee, Su-Mi
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.25 no.4
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    • pp.61-75
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    • 2017
  • Recently Following changes in the airport industry, this study aims to investigate the relationship between physical servicescape elements, a travelers' enjoyment and/or anxiety, and traveler satisfaction in the airport environment context. Six airport service scape factorsd design, scent, functional organization, air/lighting conditions, seating, and cleanlinessd should be considered when evaluating traveler response. airport design features and pleasant scent have a positive influence on traveler enjoyment, generating satisfaction. This study also provides valuable implications for airport design, organization and development. By combining previous research on servicescapes and airport design, this study confirms the significance of servicescape attributes in transit service settings in Inchon international airport. The results of this study may help airport industry practitioners understand the airport environment from a passenger's perspective.

A Probabilistic Approach to the Assessment of Phylogenetic Conservation in Mammalian Hox Gene Clusters

  • Stojanovic, Nikola;Dewar, Ken
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.118-123
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    • 2005
  • With the increasing availability of mammalian genome sequences it became possible to use large scale phylogenetic analysis in order to locate potentially functional regions. In this paper we describe a new probabilistic method for the characterization of phylogenetic conservation in mammalian DNA sequences. We have used this method for the analysis of Hox gene clusters, based on the alignment of 6 species, and we constructed a map of for indicating short and long conserved fragments and their positions with respect to the known locations of Hox genes and other elements, sometimes showing surprising layouts.

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Modal teat/analysis result correlation of folding fin (접는 날개에 대한 모드시험/해석결과 보정)

  • 양해석
    • Journal of KSNVE
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    • v.6 no.3
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    • pp.305-315
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    • 1996
  • Present paper aims at the correlation of modal characteristics of folding fin between test and analysis using an optimization theory. Folding fin is composed of a movable fin, a base fin, and many functional components related to the folding mechanism. Joint parts of folding fin in FEM are initially modeled as rigid elements resulting some difference between test and analysis in modal characteristics. Therefore, some equivalent springs representing joint parts are introduced to improve the FEM model. The springs were set as design variables, while the frequency difference between test and analysis was set as the object function. Bayesian procedure was ujsed for the minimization.

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Preparation and Characterization of Ultramicroporous Carbons for Hydrogen Storage (초미세기공을 지니는 탄소분자체의 수소저장거동)

  • Lee, Seul-Yi;Park, Soo-Jin
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.05a
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    • pp.158.1-158.1
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    • 2011
  • In this work, we prepared ultramicroporous carbons (UC) prepared by pyrolyzing poly(vinylidene fluoride) with different carbonization temperatures, and investigated the hydrogen storage behaviors. The surface functional groups and specific elements of UC were confirmed by Fourier-transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS), respectively. Textural properties were analyzed using $N_2$ adsorption isotherms at 77 K. The hydrogen storage capacity of the UC samples were investigated by BEL-HP at 298 K/10 MPa. From the results, it was found that the hydrogen storage capacity was enhanced with increasing of specific surface area, resulting from the formation of ultramicropore on the UC.

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A Study on the Interior Design Proposal for Motor Showroom as a Sales Policy (판매전략으로서의 승용차 전시매장 실내디자인에 관한 연구 -현황 분석을 통한 유형별 분류에 따른 제안-)

  • 천진희;김혜원
    • Korean Institute of Interior Design Journal
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    • no.3
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    • pp.64-70
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    • 1994
  • The objective of this study is to provide recommendations for the interir design of motor showroom as a sales policy. ten cases of motor showrooms were selected from already observed 50 showrooms in Seoul area. findings revealed that the car industries of Korea should meet the strong needs of differentiated sales policy, and the showroom design was an important factor which influenced client's pruchasing power. From these findings and analyses, this study suggests that each brand has to represent the typical total image to appeal to the consumer strongly . Additionally each showroom should be flexible in modification to meet the diverse conditions such as the location, required function and the trend of consumers. In conclusion , researchers provided 6 types of recommendations in terms of floor plan and interior elements such as circulation path, moduled furniture and objects color and lighting variation . Hopely, this research provides more functional and comfortable environment of automobile showrooms for consumers and companies.

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Integrated Framework of HoQ and AHP for Improvement of ASP Services (ASP서비스 개선을 위한 HoQ와 AHP의 적용)

  • Kim, Do-Hun
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.10a
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    • pp.253-256
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    • 2005
  • 정보기술의 관점에서, 기업 가치사슬상의 내/외부적 협력을 협력을 구현하는 방법으로ASP(Application Service Provider)를 통한 IT 아웃소싱(outsourcing)이 차세대 가상기업의 핵심 요소가 될 것으로 전망된다. 이러한 맥락에서 본 연구는 ASP 의 서비스 제공에 관한 성능을 향상시킬 수 있는 방법으로, HoQ와 AHP를 통합한 방법론을 제공한다. 그리고 이러한 통합모형을 적용하여 고객만족의 관점에서 ASP 서비스 개선을 위한 핵심 기능요소(functional elements)를 찾아 내었다. ASP 서비스의 지속적인 개선은 점차 심화되어 가는 경쟁에서 생존하기 위해 최우선적으로 중요한데, 본 연구의 HoQ/AHP 통합모형은 서비스 개선을 전략적으로 구현하는 좋은 도구가 될 것이다.

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An Application of the Localized Finite Element Method to 3-dimensional Free Surface Wave Problems (3차원 자유표면파 문제에서의 국소유한요소법의 응용)

  • K.J.,Bai;Se-Eun,Kim
    • Bulletin of the Society of Naval Architects of Korea
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    • v.24 no.3
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    • pp.1-8
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    • 1987
  • In this paper, the localized finite element method(LFEM) is applied to 3-dimensional ship motion problems in water of infinite depth. The LFEM used here is based on the functional constructed by Bai & Yeung(1974). To test the present numerical scheme, a few vertical axisymmetric bodies are treated by general 3-dimensional formulation. The computed results of hydrodynamic coefficients for a few vertical spheroids and vertical circular cylinders show good agreement with results obtained by others. The advantages of the present numerical method compared with the method of integral equation are as follows; (i) The cumbersome existence of irregular frequencies in the method of conventional integral equation is removed. (ii) The final matrix is banded and symmetric and the computation of the matrix elements is comparatively easier, whereas the size of the matrix in the present scheme is much larger. (iii) In the future research, it is possible to accommodate with the nonlinear exact free surface boundary condition in the localized finite element subdomain, whereas the linear solution is assumed in the truncated(far field) subdomain.

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