• Annals of Clinical Neurophysiology
• /
• 제23권2호
• /
• pp.69-81
• /
• 2021

Cortico-cortical evoked potential (CCEP) mapping is a rapidly developing method for visualizing the brain network and estimating cortical excitability. The CCEP comprises the early N1 component the occurs at 10-30 ms poststimulation, indicating anatomic connectivity, and the late N2 component that appears at < 200 ms poststimulation, suggesting long-lasting effective connectivity. A later component at 200-1,000 ms poststimulation can also appear as a delayed response in some studied areas. Such delayed responses occur in areas with changed excitability, such as an epileptogenic zone. CCEP mapping has been used to examine the brain connections causally in functional systems such as the language, auditory, and visual systems as well as in anatomic regions including the frontoparietal neocortices and hippocampal limbic areas. Task-based CCEPs can be used to measure behavior. In addition to evaluations of the brain connectome, single-pulse electrical stimulation (SPES) can reflect cortical excitability, and so it could be used to predict a seizure onset zone. CCEP brain mapping and SPES investigations could be applied both extraoperatively and intraoperatively. These underused electrophysiologic tools in basic and clinical neuroscience might be powerful methods for providing insight into measures of brain connectivity and dynamics. Analyses of CCEPs might enable us to identify causal relationships between brain areas during cortical processing, and to develop a new paradigm of effective therapeutic neuromodulation in the future.

• Investigative Magnetic Resonance Imaging
• /
• 제4권1호
• /
• pp.14-19
• /
• 2000

목적 : 뇌열환자에서 기능적 자기공명영상과 경두부 자기자극을 이용하여 뇌기능을 지도화하고자하였다. 대상 및 방법: 자기공명영상에서 우측 대뇌반구에 뇌열 소견이 있으며 좌측 편측부전마비를 보인 28세 남자환자를 대상으로 기능적 자기공명영상과 경두부 자기자극을 시행하였다. 임상적으로 좌측 손의 운동기능은 감소되어 있었고, 우측 손의 운동기능은 정상범주에 속하였다. 뇌기능적 자기공명영상은 EPI 기법을 이용하였고 운동자극은 1-2 Hz의 주기로 손가락을 아래위로 구부리게 하는 운동을 시행하였고 15초의 휴식기와 15초의 운동기를 반복하여 절편당 60 개의 영상을 획득하였다. 두부자기자극은 지름 90mm의 원형 자성자극기를 이용하여 maximal out-put의 80%로 자극하여 양측 단무지 외 전근에서 유발된 운동유발전위의 잠시와 진폭을 구하였다. 결과: 기능적 자기공명영상을 시행한 결과 정상적인 우측손의 운동자극시에 좌측 운동피질이 활성화되었고 좌측손의 운동자극시에는 좌측운동피질, 좌측 부가운동영역, 그리고 자측 전운동영역에 활성화소견이 나타났다. 두부자기자극에서는 우측 대뇌반구에서는 한군데에서도 운동유발 전위가 발생되지 않았다. 좌측 대뇌반구에서는 5군데에서 운동유발전위가 유발되었으며 모두 양측 단무지 외 전근에서 운동유발전위가 유발되었다. 양손에서 운동유발전위의 잠시 , 진폭 모양이 유사하였다. 결론: 뇌열환자의 손운동기능의 피지도화는 기능적 자기공명영상과 두부자기자극을 이용하여 성공적으로 시행할 수 있었다. 뇌열환자의 동측 운동경로는 동일한 운동피질로부터 기원한 동측피질척수로에 의한 것으로 추정된다.

• 한국의학물리학회:학술대회논문집
• /
• 한국의학물리학회 2002년도 Proceedings
• /
• pp.352-355
• /
• 2002

The purpose of this study was to investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the mortor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the somatomotor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients.

• 한국IT서비스학회지
• /
• 제21권2호
• /
• pp.61-84
• /
• 2022

With the recent application of deep learning to Natural Language Processing (NLP), the performance of NLP has improved significantly and NLP is emerging as a core competency of organizations. However, when encountering NLP use cases that are sporadically reported through various online and offline channels, it is often difficult to come up with a big picture of how to understand and interpret them or how to connect them to business. This study presents a framework for systematically analyzing NLP use cases, considering the characteristics of NLP techniques applicable to almost all industries and business functions, environmental changes in the era of the Fourth Industrial Revolution, and the effectiveness of adopting NLP reflecting all business functional areas. Through solving research questions based on the framework, the usefulness of it is validated. First, by accumulating NLP use cases and pivoting them around the business function dimension, we derive how NLP techniques are used in each business functional area. Next, by synthesizing related surveys and reports to the accumulated use cases, we draw implications for each business function and major NLP techniques. This work promotes the creation of innovative business scenarios and provides multilateral implications for the adoption of NLP by systematically viewing NLP techniques, industries, and business functional areas. The use case analysis framework proposed in this study presents a new perspective for research on new technology use cases. It also helps explore strategies that can dramatically improve organizational performance through a holistic approach that encompasses all business functional areas.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
• /
• 제21권2호
• /
• pp.7-15
• /
• 2015

Purpose: The purpose of this study is analyze linkage and spatial and structural characteristics of outpatient department and diagnosis/treatment area of geriatric hospitals based on quantitative analysis, according to function and corridor types. Methods: To examine structural characteristics and correlation of outpatient department and diagnosis/treatment area of six geriatric hospitals according to the corridor type, were systemized according to the function and corridor type and made into a j-graph, and an index was created by using space syntax to understand spatial characteristics. Results: 1) Different functional spaces are connected by a corridor, which, therefore, can be an axis of the connectivity and linkage of functional spaces and an important element in a clear hierarchy. 2) Treatment areas were disconnected from different functional spaces and, therefore, the accessibility was low. Many hospitals had an arrangement plan for treatment and diagnosis areas, and recent hospitals have segmented treatment areas within the rehabilitation space, which resulted in deeper space. 3) In terms of the level of integration, more integrated reception area meant shallower spatial depth, and deeper space for treatment and diagnosis areas. Implications: Spatial relation of outpatient department of geriatric hospitals was analyzed based on characteristics of the elderly.

• 대한영양사협회학술지
• /
• 제23권4호
• /
• pp.350-362
• /
• 2017

The study examined evaluated the sanitation management state of the high school foodservice operations, as measured by temperature, humidity and airborne bacteria concentration in functional areas and further identified their relationships. Data were collected from 26 high school foodservices in Gyeonggi Province. Statistical analyses were conducted with the SPSS program using descriptive analysis and spearman's correlation. The sanitation management performances in high school foodservice scored 86.85 out of 100 points and showed higher scores in the dimensions of preparation and storing management (17.85/20 points), operation management (17.78/20 points), and cooking utensil management (17.62/20 points), while the dimensions of cross contamination management as well as personal hygiene management needed action plans for prompt improvement. The airborne bacteria concentration was highest in the dining area (179.2 CFU/plate), and requiring action plans for improvement. The relative humidity in functional areas ranged from 66.5% in the receiving area to 74.4% (dish-washing area) and the temperature of the preparation area showed an average of $25.1^{\circ}C$ with the highest of $35.4^{\circ}C$ in the dish-washing area. In terms of the relationships among airborne bacteria, temperature, and humidity, the concentration of airborne bacteria was negatively correlated with and temperature in the dish-washing area (r= -0.693, P<0.05), and no other significances were shown in the other areas.

• 한국데이타베이스학회:학술대회논문집
• /
• 한국데이타베이스학회 1997년도 International Conference MULTIMEDIA DATABASES on INTERNET
• /
• pp.215-269
• /
• 1997

Outline $\textbullet$ Introduction $\textbullet$ Multimedia - Types of Data - Motivation - Key issue - Hardware Products - Application Areas $\textbullet$ Agents - Rationale for Agents - Sedentary vs. Mobile - Functional Categories - Application Areas $\textbullet$ Data Mining - 2-D Framework for Data Mining Tools - Classification of Tool - Application Areas - Learning Methodologies ＊ Case Based Reasoning ＊ Neural Networks ＊ Statistical Learning： Orthogonal Arrays ＊ Multi-strategy Learning $\textbullet$ Case Study - Finbot $\textbullet$ Conclusion

• 한국농공학회:학술대회논문집
• /
• 한국농공학회 2003년도 학술발표논문집
• /
• pp.115-118
• /
• 2003

This study was carried out to analyse the central functions of district-load areas (Eup or Myon in Korea) in the neighbourhood zone of Saemankeum Reclamation Area. From the calculation results of their functional indices, only 4 areas were selected as the second-order centers, while remaining 12 areas as the third-order centers. (key villages)

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제28권4호
• /
• pp.197-212
• /
• 2017

Objectives: This study aims to supplement the limitations of the preliminary study and expand the use of the Child-Adolescent Functional Assessment Scale by providing standardized T-scores for measuring function in different areas, as well as guidelines for their interpretation. Methods: The Child-Adolescent Functional Assessment Scale and Korean-Child Behavior Checklist were administered to a total of 623 individuals, including 467 parents of emotionally and behaviorally disturbed elementary school students, 45 parents of emotionally and behaviorally disturbed middle school adolescents and 111 parents of elementary school students with developmental disorders, as well as to a control group consisting of 186 parents of mainstream elementary school children in the Seoul metropolitan area. Results: In contrast to the preliminary study, the emotional domain was disassociated into two factors, negative affect and emotion regulation, and the coefficient of determination for misconduct was increased significantly. Also, the overall reliability and validity of the Child-Adolescent Functional Assessment Scale were similar to those in the preliminary study, and the item structure was consistent. This study provides standardized T-scores of function in different areas based on the revised scale, and provides guidelines for their interpretation. Conclusion: The Child-Adolescent Functional Assessment Scale can assist the Child Global Assessment in Functioning in providing the information necessary for case management and treatment planning by comparing the impairment severity in each area of functioning, and also determining changes in behavior and function after treatment interventions. On the other hand, this scale has yet to clearly distinguish between rebellious behavior and misconduct. Further research is necessary to provide standards for more diverse age groups and for its utilization.

• 한국의류학회지
• /
• 제39권2호
• /
• pp.271-286
• /
• 2015

This study presented functional designs for development of functional compression wear for men in their forties based on body muscles as well as designed 2D patterns using 3D standard body form data of men in their forties. Patterns with an optimal stretch rate were proposed through a comfort evaluation. Different material was used for different areas such as the sports ability strengthening areas including body parts that often move for sports (such as the shoulders, abdomen and lower arm), areas that require ventilation for perspiration (such as the chest and back center, and armpits), and stable form areas (such as the chest, waist and elbows). The front and back surface areas of the developed pattern was an average 102.4% size compared to the body surface area. The results indicated that the 90% reduction pattern showed changes in pressure value according to area of movement, had the best breathability when worn, and had the best, most comfortable fit compared to the other subjects. The clothing pressure values of the pattern were around 22.1-23.4mmHg for the arm area (which has a big movement range and has many muscles) and 10.4-11.8mmHg for chest and abdomen areas related to major organs and breathing, indicating appropriate clothing pressure. A compression wear top pattern with pressure appropriate to the target age range and excellent appropriateness for the body form will be developed for men in their forties. A study method will be proposed to develop design technology for ergonomic compression wear tops with excellent fit and comfort.