• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.1-2
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• 2006

Polymer architecture plays a great role in determining the properties of functional polymers. This lecture will explore the design and the synthesis of polymers with controlled architecture and functionality. Especially featured will be star and dendritic architectures where the functional group placement and the molecular shape can be controlled. This will be followed by examples of applications illustrated with a few model systems of functional polymers designed for use in areas such as organic electronics, catalysis, surface patterning, separation and molecular recognition, and polymer therapeutics.

• Journal of Korean Neurosurgical Society
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• 제45권4호
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• pp.219-223
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• 2009

Objective : Functional magnetic resonance imaging (fMRI) is frequently used to localize language areas in a non-invasive manner. Various paradigms for presurgical localization of language areas have been developed, but a systematic quantitative evaluation of the efficiency of those paradigms has not been performed. In the present study, the authors analyzed different language paradigms to see which paradigm is most efficient in localizing frontal language areas. Methods : Five men and five women with no neurological deficits participated (mean age, 24 years) in this study. All volunteers were right-handed. Each subject performed 4 tasks, including fixation (Fix), sentence reading (SRI. pseudoword reading (PR), and word generation (WG). Fixation and pseudoword reading were used as contrasts. The functional area was defined as the area(s) with a t-value of more than 3.92 in fMRI with different tasks. To apply an anatomical constraint, we used a brain atlas mapping system, which is available in AFNI, to define the anatomical frontal language area. The numbers of voxels in overlapped area between anatomical and functional area were individually counted in the frontal expressive language area. Results : Of the various combinations, the word generation task was most effective in delineating the frontal expressive language area when fixation was used as a contrast (p<0.05). The sensitivity of this test for localizing Broca's area was 81 % and specificity was 70%. Conclusion : Word generation versus fixation could effectively and reliably delineate the frontal language area. A customized effective paradigm should be analyzed in order to evaluate various language functions.

• 한국체육학회지인문사회과학편
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• 제55권4호
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• pp.285-292
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• 2016

스포츠 이벤트에 대한 인식 변화와 함께 스포츠 이벤트 비용을 최적화시키면서 효과를 극대화시키기 위한 노력이 나타나고 있다. 이를 위한 출발점은 적합한 조직 구조를 설계하는 것이며 기반이 될 수 있는 기능 영역을 매니지먼트 관점에서 명확히 제시할 필요가 있다. 이에 본 연구의 목적은 매니지먼트 측면에서 올림픽에 대한 기능 영역을 분류하는 것이다. 연구 결과를 도출하기 위하여 총 4단계의 델파이 조사를 현장 조직 2명, 학계 2명, 서비스 제공 조직 2명, 연구소 1명과 같이 7명의 전문가와 함께 진행하였다. 1단계에서는 조직위 중 기능영역을 69개로 가장 세분화한 2016 리오올림픽 사례를 대상으로 항목화 및 범주화 실시하였다. 2단계에서는 1단계에서 도출된 결과에 대한 의견을 수렴하였다. 3단계에서는 2단계까지 나타난 핵심적인 논의사항에 대한 의견을 수렴하였다. 4단계에서는 최종 결과를 도출하기 위한 통합논의를 실시하였다. 이러한 과정을 거쳐 총 22개의 주요한 기능 영역이 도출되었다.

• 한국자기공명학회논문지
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• 제6권2호
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• pp.89-93
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• 2002

We report a preliminary fMRI evidence of modulation of somatomotor areas by acupuncture in GB34 acupoint. GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MR scanner, functional MR imaging was performed in five normal volunteers in two stimulation paradigms; acupuncture manipulation on GB34 and sham points. Group analysis form five individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. Our results suggest that acupuncture fMRI study can be safely conducted in 3T environment and stimulation in GB34 modulate the cortical activities of the somatomotor area in human.

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2002년도 International Symposium on Magnetic Resonance
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• pp.21-25
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• 2002

We report a preliminary fMRI evidence of modulation of somatomotor areas by acupuncture in GB34 acupoint. GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MR scanner, functional MR imaging was performed in five normal volunteers in two stimulation paradigms; acupuncture manipulation on GB34 and sham points. Group analysis from five individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6％ whereas very few areas were activated when sham stimulation is given. Our results suggest that acupuncture fMRI study can be safely conducted in 3T environment, and stimulation in GB34 modulate the cortical activities of the somatomotor area in human.

• 한국환경복원기술학회지
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• 제17권1호
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• pp.173-184
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• 2014

Riparian areas are significant functional grounds for inhabiting ecological system on the river such as the self-regulation of the water quality and the foundation of important corridors. For such functional device to operate, consecutive land purchase scheme that prioritizes targeted areas with high pollutant load rate imposes sustainable development of the ecological riparian belt. The purpose of this study is focused on measuring the methodology for selecting land purchse order before establishing riparian belt in accordance with pollution loading estimation and the basin approach. The Yeongsan and Seomjin river which includes targeted areas of the land purchase have been classified into the large-medium-small(standard basin) influence areas based on their catchment rage, which than sub-divided the research area of Juam lake by 38 small basins and 223 units. Small basins with the high pollution load rates have been assessed as the first prioritized targets. For the second priority, the condition of the point pollutant sources, original area of the targets, original restored area were concerned. The final decision of the land purchase order targeted only those within 50 meter range from the basin. To validate the accumulated data, the on-site investigation went along the targeted zones, which the result shows that all prioritized areas included both point and non-point pollutant sources, and had not a small originally restored areas.

• 한국경제지리학회지
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• 제23권1호
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• pp.1-17
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• 2020

본 연구는 기업 간 거래망을 활용하여 지역 간 경제적 연계를 확인하고 경제적 상호의존성에 기초한 기능적 경제권을 설정하는데 그 목적이 있다. 기존의 경제권은 이미 알려진 행정도 경계나 문화적 동질성을 기준으로만 설정되거나 실증자료를 활용하더라도 통근, 인구이동, 화물흐름 등 경제활동을 충분히 설명하지 못하는 자료에만 의존하였다. 본 연구는 이러한 한계를 극복하기 위해 한국기업데이터의 CRETOP+ 데이터베이스를 활용하여 실제 기업 간 거래망을 구축하고, 커뮤니티 발견법을 적용해 우리나라의 기능적 경제권을 파악하였다. 분석결과 거래망에 따라 6~7개의 경제권이 도출되었다. 특히 수도권, 충청권, 강원권을 통합한 하나의 거대한 경제권역이 형성되어 있었으며, 전북, 전남은 서로 간의 기업 간 거래빈도가 매우 낮아 호남권으로 묶이기보다 별도의 경제권을 형성하고 있는 것으로 나타났다. 대구, 경북의 경제권과 부산, 경남의 경제권이 각각 존재하는 것으로 나타났지만 울산, 경주, 포항은 도 경계를 넘어서 별도의 권역을 형성하고 있는 것으로 나타났다. 이를 통해 본 연구는 향후 국가균형발전정책에서 실증 자료에 기반한 정책공간의 설정이 필요함을 주장한다.

• 대한의용생체공학회:의공학회지
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• 제32권1호
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• pp.74-78
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• 2011

Although recent studies have shown the usibility of [F-18]FDG small animal Positron Emission Tommography (PET) as a functional neuroimaging technique in behavioural small animal study, researches showing the detection power of functional changes in the brain are still limited. Thus, in the study, we performed [F-18]FDG small animal PET neuroimaging in the well-established fear behavioural experiment. Twelve rats were exposed on cat for 30 minutes after the [F-18]FDG injection. As a result, the brain activity in bilateral amygdala areas significantly increased in the fear condition. In addition, the fear condition evoked the functional activities of hypothalamus, which seemed to be related to the response to stress. These clear localization of fear related brain regions may reflect that a functional neuroimaging technique using [F-18]FDG small animal PET has functional detectibility enough to be applied in small animal behavioral research.

• 한국약용작물학회지
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• 제21권4호
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• pp.282-288
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• 2013

Gastrodia elata Blume is a achlorophyllous orchid plant that has been used in traditional medicine to treat many human illnesses, such as vertigo, hemiplegia, and epilepsy. It contains three major pharmacological substances; gastrodin, ergothioneine, and vanillyl alcohol. Here we investigated the quantitative changes in those functional components by cultivation conditions and harvest times. The content of ergothioneine was different with cultivation areas, while gastrodin accumulated the higher levels than vanillyl alcohol regardless of cultivation areas. The smaller tubers contained the higher concentrations of gastrodin and the lower concentrations of ergothioneine than did the larger tubers. The cultivation under sun shade screen increased the concentrations of both gastrodin and vanillyl alcohol but decreased the levels of ergothioneine. We also determined the contents of functional substances depending on the harvest times. The concentration of gastrodin was higher in October than in April, while the level of ergothioneine was higher in April than in October. Interestingly, the use of sexually propagated seed tubers produced 1.9 times higher levels of gastrodin compared to vegetatively propagated seed tubers. In this study, we found that three major functional substances in G. elata tubers altered depending on various cultivation practices, which might be important to increase the economic values of G. elata tubers.

• 대한구순구개열학회지
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• 제15권1호
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• pp.29-38
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• 2012

A 20 year-old cleft lip and palate patient came for occlusal rehabilitation, but the constricted maxilla and early loss of posterior teeth called for an unusual treatment modalities. Distraction osteogenesis in the edentulous areas followed by artificial bone graft, dental implant along with orthodontic tooth movement were planed. Multidisciplinary treatment enabled both esthetic and functional oral rehabilitation of this patient.