• 대한산업공학회지
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• 제29권3호
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• pp.230-238
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• 2003

The configuration design of a mechanical product can be efficiently performed when it is based on the functional modeling. There are methodologies, which decompose function from the abstract level to the concrete level and match the functions to physical parts. But it is difficult to carry out an innovative design when the function is matched only to a pre-detined part. This paper describes the configuration design process of a mechanical product with a design expert system, which uses function taxonomy and TRIZ theory. The expert system can propose a functional modeling of a new part. which is not in the existing parts list. The abstraction levels of design knowledge are introduced, which describe the operation of mechanical product in the levels of abstraction. This is the theoretical background of using knowledge of function and TRIZ for configuration design. The expert system is adequate to control this design knowledge. which expresses knowledge of functional modeling, mapping rules between functions and parts, selection of parts, and TRIZ theory. The hierarchy of functions and machine parts are properly expressed by classes and objects in the expert system. A design expert system has been implemented for the configuration design of a train bogie, and a new brake system of the bogie is introduced with the aid of TRIZ's 30 function groups.

• Genomics & Informatics
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• 제16권4호
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• pp.23.1-23.5
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• 2018

Virus taxonomy was initially determined by clinical experiments based on phenotype. However, with the development of sequence analysis methods, genotype-based classification was also applied. With the development of genome sequence analysis technology, there is an increasing demand for virus taxonomy to be extended from in vivo and in vitro to in silico. In this study, we verified the consistency of the current International Committee on Taxonomy of Viruses taxonomy using an in silico approach, aiming to identify the specific sequence for each virus. We applied this approach to norovirus in Caliciviridae, which causes 90% of gastroenteritis cases worldwide. First, based on the dogma "protein structure determines its function," we hypothesized that the specific sequence can be identified by the specific structure. Firstly, we extracted the coding region (CDS). Secondly, the CDS protein sequences of each genus were annotated by the conserved domain database (CDD) search. Finally, the conserved domains of each genus in Caliciviridae are classified by RPS-BLAST with CDD. The analysis result is that Caliciviridae has sequences including RNA helicase in common. In case of Norovirus, Calicivirus coat protein C terminal and viral polyprotein N-terminal appears as a specific domain in Caliciviridae. It does not include in the other genera in Caliciviridae. If this method is utilized to detect specific conserved domains, it can be used as classification keywords based on protein functional structure. After determining the specific protein domains, the specific protein domain sequences would be converted to gene sequences. This sequences would be re-used one of viral bio-marks.

• 한국문헌정보학회지
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• 제48권4호
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• pp.297-322
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• 2014

본 연구의 목적은 KCI의 인문학, 사회과학, 예술체육 분야 저자키워드를 대상으로 의미적, 형태적 분석을 통해 기존에 연구된 개념범주 텍사노미의 적합성을 확인하고 실용적인 개선 방안을 제시하는 것이다. 연구를 통해 '실체, 추상, 일반/공통, 개체'의 네 개 최상위수준의 개념범주를 보다 구체적이고 핵심 개념이 반영된 일곱 개의 범주 '개체, 활동/기능, 특성, 이론/방법, 형식/틀, 일반/공통, 인스턴스'로 변경하였다. 중위범주와 하위범주의 경우 신설, 세분화, 통합, 삭제, 이동 등의 방법으로 개념범주의 계층 구조를 단순화시키고 범주 간 용어분포의 불균형을 개선하였다. 구조적학술용어사전(STNet)을 테스트베드로 삼아 수정된 개념범주 텍사노미를 적용한 결과 용어의 분포가 균형적으로 이루어지고, 용어의 속성 표현이 상세화되는 효과를 보이는 것으로 나타났다.

• 한국안전학회지
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• 제18권2호
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• pp.104-118
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• 2003

It has been criticized that conventional human reliability analysis (HRA) methodologies for probabilistic safety assessment (PSA) have been focused on the quantification of human error probability (HEP) without detailed analysis of human cognitive processes such as situation assessment or decision-making which are crticial to successful response to emergency situations. This paper introduces a new human reliability analysis (HRA) methodology, AGAPE-ET (A guidance And Procedure for Human Error Analysis for Emergency Tasks), focused on the qualitative error analysis of emergency tasks from the viewpoint of the performance of human cognitive function. The AGAPE-ET method is based on the simplified cognitive model and a taxonomy of influencing factors. By each cognitive function, error causes or error-likely situations have been identified considering the characteristics of the performance of each cognitive function and influencing mechanism of PIFs on the cognitive function. Then, overall human error analysis process is designed considering the cognitive demand of the required task. The application to an emergency task shows that the proposed method is useful to identify task vulnerabilities associated with the performance of emergency tasks.

• Genomics & Informatics
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• 제11권1호
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• pp.52-54
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• 2013

Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD). A total of 12,908 DNAJs and 4,886 DNAKs were identified from 339 eukaryotic genomes in the EDD. Kingdom-wide comparison of DNAJ/K families provides new insights on the evolutionary relationship within these families. Empowered by 'class', 'cluster', and 'taxonomy' browsers and the 'favorite' function, the EDD provides a versatile platform for comparative genomic analyses of DNAJ/K families.

• 약학회지
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• 제39권6호
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• pp.585-592
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• 1995

Soil microorganisms producing immunomoduators that can restore ultraviolet B (UVB) radiation-induced suppression of the immune response were screened in vitro. Exposure of freshly isolated murine epidermal cells (EC) to $180{\;}J/m^{2}$ of UVB radiation resulted in approximately 90% impairtnent of accessory cell function, as measured by their ability to support anti-CD3 monoclonal antibody-induced T-cell mitogenesis. When the culture supenmtants of 150 actinomycete strains were exanuned for their capacity to prevent or repair the UVB-induced impairment of accessory cell function, 4 of them were identified to contain immunomodulators that can restore the decreased accessory cell finiction. The soil isolate that showed the most effective restorative activity, G40025. was selected and fturther characters Addition of 10.mu.l of the culture supernatant of G40025 grown in G-media to cultures of UVB-irradiated EC right after UVB-irradiation restored the decreased accessory cell function by 58%. The immunomodtdator produced by G40025 appeared to be stable at 100.deg. C for 10 min. Taxonomical studies by cultural, morphological, and physiological characterization showed that the soil isolate, G40025, belongs to the genus Streptomyces.

• 한국환경복원기술학회지
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• 제4권3호
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• pp.38-48
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• 2001

A wetland is an ecosystem which is the most useful and highly-energetic transition area. This study has been carried out to develop the wetland function assessment methods and apply on the natural wetlands (Mul-young-ari wetland in Jeju-island and Bangdong wetland in Taejon Metropolitan city) using RAM (Rapid Assessment Method). The RAM is useful method for assessing the wetland functions in terms of general functions acquired by once or twice onsite surveying. Eight functions of 2-12 variables each are analyzed for assessing the wetland functions. The results are as follows : 1) The conservation values of two wetlands are "High". 2) In Mul-young-ari wetland, such functions as groundwater discharge, floral diversity and wildlife habitat, shoreline/stream bank protection are relatively high, but some functions such as flood/storm water storage, aesthetics and recreation are "Moderate" - "High". 3) In Bangdong wetland, such functions as floral diversity and wildlife habitat, groundwater discharge, flood/storm water storage, aesthetics and recreation are high, and another functions are "Moderate" - "High". The taxonomy of this study stems from assessing functions of inland wetlands using indices of RAM. So It is needed that consequent studies are to be performed with verifying the variables and indices.

• 한국지구과학회지
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• 제26권7호
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• pp.640-651
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• 2005

본 연구는 Klopfer의 교육목표 분류를 이용하여 한국의 제7차 교육과정의 중학교 7학년 과학과의 교육목표와 제7차 교육과정에 따른 중학교 교과서에 나타난 학습 목표를 분석하여 교과서에 반영된 교육목표가 교육과정상의 요구 목표와 어느 정도 부합하는지를 알아보고 문제점을 분석하여 제시함으로써 교육과정에서 요구하는 목표와 교과서가 연계성을 가지도록 하는데 있다. 연구결과 제7차 교육과정의 과학과 교육목표는 Klopfer의 교육목표 분류5의 조작적 기능(G.0)을 제외한 전 범주에 걸쳐 그 목표를 설정하고 있으며, 정의적인 영역(범주 $H.0\~I.0$)을 더욱 강조하고 있다. 그러나 제7차 교육과정의 중학교 교과서는 NSTA의 권장 목표 비율과 비교해 볼 때 인지적 영역에 더욱 비중을 두고 출판되었으며, 교과서에 지향(범주 I.0)에 관한 목표가 전혀 언급되지 않고 있었다.

• Journal of Forest and Environmental Science
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• 제39권3호
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• pp.180-194
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• 2023

This study characterize, classify and evaluates the function of topography on spatial variability of some selected soil properties to assist in designing land management that support uniform agricultural production. The study site, an agricultural land, was part of the derived savanna zone in southwest Nigeria. Four soil profile pits each were established along two delineated toposequence and described following the FAO/UNESCO guidelines. Samples were collected from the identified genetic horizons. Properties of four soil series developed on different positions of the two delineated Toposequence viz upper, middle, lower slopes and valley bottom positions respectively were studied. The soil samples were analysed for selected physical and chemical properties and data generated were subjected to descriptive and inferential statistics. The results showed that soil colour, depth and texture varied in response to changes in slope position and drainage condition. The sand content ranged from 61 to 90% while the bulk density ranged between 1.06 g cm^-3 to 1.68 g cm^-3. The soils were neutral to very strongly acid with low total exchangeable bases. Available phosphorus value were low while the extractable micronutrient concentration varied from low to medium. Soils of Asejire and Iwo series mapped in the study area were classified as Typic isohyperthermic paleustult, Apomu series as Plinthic isohyperthermic paleustult and Jago series as Aquic psamment (USDA Soil Taxonomy). These soils were correlated as Lixisol, Plinthic Lixisol and Fluvisol (World Reference Based), respectively. Major agronomic constraints of the soils associations mapped in the study area were nutrient availability, nutrient retention, slope, drainage, texture, high bulk density and shallow depth. The study concluded that the soils were not homogenous, shows moderate spatial variation across the slope, had varying potentials for sustainable agricultural practices, and thus, the agronomic constraints should be carefully addressed and managed for precision agriculture.

• 한국병원경영학회지
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• 제28권2호
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• pp.9-20
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• 2023

Purpose: This study classified the actual functions of geriatric hospitals and examined the differences in their characteristics, in order to provide a basis for discussions on defining the functions of geriatric hospitals and how to pay for care. Methodology: This study used various administrative data such as health insurance data and long-term care insurance data. Cluster analysis was used to categorize geriatric hospitals. To examine the validity of the cluster analysis results, we conducted a discriminant analysis to calculate the accuracy of the classification. To examine cluster characteristics, we examined structure, process, and outcome indicators for each cluster. Findings: The cluster analysis identified five clusters. They were geriatric hospitals with relatively short stays for cancer patients(cluster 1; cancer patient-centered), geriatric hospitals with relatively large numbers of patients using rehabilitation services(cluster 2; rehabilitation patient-centered), geriatric hospitals with a high proportion of relatively severe elderly patients(cluster 3; severe elderly patient-centered), geriatric hospitals with a high proportion of mildly ill elderly patients with various conditions(cluster 4; mildly ill elderly patient-centered), and geriatric hospitals with a significantly higher proportion of dementia patients(cluster 5; dementia patient-centered). The largest number of geriatric hospitals were categorized in clusters 4 and 5, and the structure and process indicators for these clusters were generally lower than for the other clusters. Practical Implications: We have confirmed the existence of geriatric hospitals where the medical function, which is the original purpose of a geriatric hospital, has been weakened. It has been observed that the quality level of these geriatric hospitals is likely to be lower compared to hospitals that prioritize enhanced medical functions. Therefore, it is suggested to consider the conversion of these geriatric hospitals into long-term care facilities, and careful consideration should be given to the review of care-giver payment coverage.