• Title/Summary/Keyword: Function Analysis Phase

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Impacts of Urban Green Spaces on Air Quality (도심지역 녹지의 국지적 대기환경영향에 관한 연구)

  • Joo, Hyun Soo;Kim, Seogcheol
    • Korean Chemical Engineering Research
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    • v.47 no.3
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    • pp.386-393
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    • 2009
  • This study was to find out the quantitative relation between urban treed area(neighborhood parks) and the atmosphere environment in real condition, focusing the gas-phase non-reacting air pollutants(SOx and NOx) decreasing function of trees in urban area. It also developed a quantitative analysis method for evaluation of the atmosphere influence in the type of treed areas. We set up the Pagoda Park in Seoul and its neighbourhood as a modelling area to analyse air quality impacts by urban neighbourhood park trees. From the modelling result of the Pagoda Park case study, it is concluded that urban neighbourhood park has an important meaning to suppress construction of emission sources which drive the urban polluted air quality worse, even though park's trees have relatively small air purifying function. Especially in the urban area severely contaminated by air pollutants, the first considered air quality management policy is conservation of green spaces in neighborhood park.

Standards for Evaluation of a Center for Scientifically Gifted Education (과학영재교육센터 평가 기준 개발)

  • Choi, Don-Hyung;Kang, Wan;Son, Yeon-Ah;Jeon, Young-Seok
    • Journal of Gifted/Talented Education
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    • v.11 no.2
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    • pp.59-85
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    • 2001
  • Offered in this paper are standards for evaluation of a center for scientifically gifted education attached to a university. Various methods of study are used, such as review of literature, professional meetings, seminars, and discussion groups. To implement this study we first analyzed the current status and problem of the center through examination of already published research in regard to scientifically gifted education. Based on this analysis, we then identified the direction and framework of evaluation of a center for scientifically gifted education attached to a university that could function as a local education center for the gifted. After this, we designed detailed standards for evaluation for such a center in regard to direction, organization, procedures and methods for selection of a center, curriculum development, and strategies of instruction and evaluation according to the characteristics, phase, and function of the center as identified. Lastly, we presented a framework for evaluation concluding standards and methods for evaluation classified by the domains and times of evaluation we had explored. Plans for evaluation of the center as described here, will provide meaningful suggestions enabling centers for scientifically gifted education to improve the quality of their institutions'educational environment.

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An Approximate Cost Estimating Model for Eco-River Facility Construction Project at Planning Stage (자연형 하천공사 개략공사비 산정모델의 개발)

  • Choi, In-Wook;Lee, Si-Wook;Woo, Sung-kwon
    • Korean Journal of Construction Engineering and Management
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    • v.10 no.5
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    • pp.104-112
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    • 2009
  • After the middle of 90's, the eco rivers maintenance enterprise was propelled about city rivers. The environmental function is more emphasized because of revising the rivers law enforced at 2008.4. Also, the field of application is being magnified. It is difficult to apply that the conceptual public work expense estimating model of the rivers which adjusts a focus at open channel rivers excepts the small-scale rivers maintenance public work. The research presents a eco rivers public work conceptual public work expense estimating model frame work. It suits the change of the rivers environmental renewal construction paradigm. It develops the conceptual public work expense estimating plan of the rivers at the planning phase using the collection and analysis of the data. As a result, riffle, spur dyke, stepping stones, fish way and etc are added. Consequently, it brings the hydrophilic function is considered seriously conceptual public work expense estimating model of the eco rivers.

Microbial Rhodopsins: Genome-mining, Diversity, and Structure/Function

  • Jung, Kwang-Hwan;Vishwa Trivedi;Yang, Chii-Shen;Oleg A. Sineschekov;Elena N. Spudich;John L. Spudich
    • Journal of Photoscience
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    • v.9 no.3
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    • pp.45-48
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    • 2002
  • Microbial rhodopsins, photoactive 7-transmembrane helix proteins that use retinal as their chromophore, were observed initially in the Archaea and appeared to be restricted to extreme halophilic environments. Our understanding of the abundance and diversity of this family has been radically transformed by findings over the past three years. Genome sequencing of cultivated microbes as well as environmental genomics have unexpectedly revealed archaeal rhodopsin homologs in the other two domains of life as well, namely Bacteria and Eucarya. Organisms containing these homologs inhabit such diverse environments as salt flats, soil, freshwater, and surface and deep ocean waters, and they comprise a broad phylogenetic range of microbial life, including haloarchaea, proteobacteria, cyanobacteria, fungi, and algae. Analysis of the new microbial rhodopsins and their expression and structural and functional characterization reveal that they fulfill both ion transport and sensory functions in various organisms, and use a variety of signaling mechanisms. We have obtained the first crystallographic structure for a photosensory member of this family, the phototaxis receptor sensory rhodopsin II (SRII, also known as phoborhodopsin) that mediates blue-light avoidance by the haloarchaeon Natronobacterium pharaonis. The structure obtained from x-ray diffraction of 3D crystals prepared in a cubic lipid phase reveals key features responsible for its spectral tuning and its sensory function. The mechanism of SRII signaling fits a unified model for transport and signaling in this widespread family of phototransducers.

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Study on Earthquake Hazard Response Process by 'Pohang Earthquake' Case Analysis (포항지진사례 분석을 통한 지진재난 대응 프로세스에 관한 연구)

  • Kang, Hyeong Gu;Park, Ki-Jong;Kim, HyeWon
    • The Journal of the Korea Contents Association
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    • v.21 no.1
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    • pp.561-571
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    • 2021
  • The 2017 Pohang earthquake left us with issues related to long-term repair and restoration from massive earthquake damage. The existing Earthquake response manual was insufficient to consider the flow of earthquake disaster work and the characteristics of long-lasting earthquake disaster. Accordingly, It is important to analyze and record how to earthquake response work was carried out during the Pohang earthquake. The functions that require the most work and manpower in the event of an earthquake disaster were emergency life stabilization support, facility emergency recovery, and energy functional restoration. As a result of analyzing the difficulties and problems of disaster response by function, it was found that the prevention and preparation for damage in advance was insufficient for each function. In conclusion, we subdivided the response step applied with the concept of time and presented the overall work flow process for thirteen collaboration functions. It is expected that this result will help disaster managers to work effectively in the event of a large scale earthquake.

Intrathecal administration of naringenin improves motor dysfunction and neuropathic pain following compression spinal cord injury in rats: relevance to its antioxidant and anti-inflammatory activities

  • Fakhri, Sajad;Sabouri, Shahryar;Kiani, Amir;Farzaei, Mohammad Hosein;Rashidi, Khodabakhsh;Mohammadi-Farani, Ahmad;Mohammadi-Noori, Ehsan;Abbaszadeh, Fatemeh
    • The Korean Journal of Pain
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    • v.35 no.3
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    • pp.291-302
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    • 2022
  • Background: Spinal cord injury (SCI) is one of the most debilitating disorders throughout the world, causing persistent sensory-motor dysfunction, with no effective treatment. Oxidative stress and inflammatory responses play key roles in the secondary phase of SCI. Naringenin (NAR) is a natural flavonoid with known anti-inflammatory and antioxidative properties. This study aims at evaluating the effects of intrathecal NAR administration on sensory-motor disability after SCI. Methods: Animals underwent a severe compression injury using an aneurysm clip. About 30 minutes after surgery, NAR was injected intrathecally at the doses of 5, 10, and 15 mM in 20 µL volumes. For the assessment of neuropathic pain and locomotor function, acetone drop, hot plate, inclined plane, and Basso, Beattie, Bresnahan tests were carried out weekly till day 28 post-SCI. Effects of NAR on matrix metalloproteinase (MMP)-2 and MMP-9 activity was appraised by gelatin zymography. Also, histopathological analyses and serum levels of glutathione (GSH), catalase and nitrite were measured in different groups. Results: NAR reduced neuropathic pain, improved locomotor function, and also attenuated SCI-induced weight loss weekly till day 28 post-SCI. Zymography analysis showed that NAR suppressed MMP-9 activity, whereas it increased that of MMP-2, indicating its anti-neuroinflammatory effects. Also, intrathecal NAR modified oxidative stress related markers GSH, catalase, and nitrite levels. Besides, the neuroprotective effect of NAR was corroborated through increased survival of sensory and motor neurons after SCI. Conclusions: These results suggest intrathecal NAR as a promising candidate for medical therapeutics for SCI-induced sensory and motor dysfunction.

The Study of Trnascriptional Regulated Gene, $hrp^{2+}$, in Yeast

  • Choi, In-Soon
    • Journal of Life Science
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    • v.11 no.2
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    • pp.111-115
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    • 2001
  • This study was designed to clone the SNF2/SW12 helicase-related genes from the fission yeast Schizosaccha-romyces pombe and thereafter to elucidate the common functions of the proteins in this family. The $hrp^{2+}$gene was cloned by polymerase chain reaction amplification using degenerative primers from conserved SNF2 motifs within the ERCC6 gene, which encodes a protein involved in DNA excision repair. Like other SNF2/SW12 family proteins, the deduced amino acid sequence of Hrp2 contains DNA-dependent ATPase/7 helicase domains as well as the chromodomain and the DNA binding domain. This configuration is similar to that of mCHD1 (mouse chromo-ATPase/helicase-DNA-dinding protein 1), suggesting that Hrp2 is a S. pombe homolog of mCHD1, which is thought to function in altering the chromatin structure to control the gene expression. To characterize the function of Hrp2, 4 Uracil-Hrp2 fusion protein, it was purified near homogeneity by affinity chromatography on $Ni^{2+}$-NTA agarose, DEAE-Sepharose ion exchange arid Sephacryl S-200 gel filtration chromatographies. The purified fusion protein exhibited DNA-dependent ATPase activity, which was stimulated by both double-stranded and single-stranded DNA. To determine the steady-state level of $hrp^{2+}$ transcripts during growth, cells were cultured in medium and collected at every 2hr to prepare total RNAs. The northern blot analysis showed that the level of $hrp^{2+}$ transcripts reached its maximum before the cells entered the exponential growth phase and then decreased gradually, This result implies that Hrp2 may be required at early stages of cell growth.h.

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Comparison and Evaluation of Dynamic Modulus of Hot Mix Asphalt with Different Shift Factors (전이함수 결정법에 따른 아스팔트 혼합물의 동탄성계수 비교평가)

  • Kim, Hyun-Oh;Lee, Kwan-Ho
    • International Journal of Highway Engineering
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    • v.7 no.1 s.23
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    • pp.49-61
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    • 2005
  • The dynamic modulus of hot mix asphalt can be determined according to the different combinations of testing temperature and loading frequency. The superposition rule is adapted to get the master curve of dynamic modulus for each hot mix asphalt. There are couple of different methods to get the shift factor which is a key for making the master curve. In this paper, Arrehnius, 2002 AASHTO, and experimental method was employed to get the master curve. Evaluation of dynamic modulus for 25mm base course of hot mix asphalt with granite aggregate and two asphalt binders(AP-3 and AP-5) was carried out. Superpave Level 1 Mix Design with gyratory compactor was adopted to determine the optimum asphalt binder content(OAC) and the measured ranges of OAC were between 4.1% and 4.4%. UTM was used for laboratory test. The dynamic modulus and phase angle were determined by testing on UTM, with 5 different testing temperature(-10, 5, 20, 40, & $55^{\circ}C$) and 5 different loading frequencies(0.05, 0.1, 1, 10, 25 Hz). Using the measured dynamic modulus and phase angle, the input parameters of Sigmoidal function equation to represent the master curve were determined and these will be adopted in FEM analysis for asphalt pavements. The shift factor and activation energy for determination of master curve were calculated.

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RHEOLOGICAL CHARACTERIZATION OF COMPOSITES USING A VERTICAL OSCILLATION RHEOMETER (수직 진동형 Rheometer를 이용한 복합레진의 유변학적 성질의 측정)

  • Lee, In-Bog;Cho, Byung-Hoon;Son, Ho-Hyun;Lee, Sang-Tag;Um, Chung-Moon
    • Restorative Dentistry and Endodontics
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    • v.29 no.6
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    • pp.489-497
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    • 2004
  • Objective: The purpose of this study was to investigate the viscoelastic properties related to handling characteristics of composite resins, Methods: A custom designed vertical oscillation rheometer (VOR) was used for rheological measurements of composites. The VOR consists of three parts: (1) a measuring unit, (2) a deformation induction unit and (3) a force detecting unit, Two medium viscous composites, Z100 and Z250 and two packable composites, P60 and SureFil were tested. The viscoelastic material function, including complex modulus $E^{*}$ and phase angle ${\delta}$, were measured. A dynamic oscillatory test was used to evaluate the storage modulus (E'), loss modulus (E") and loss tangent ($tan{\delta}$) of the composites as a function of frequency ($\omega$) from 0.1 to 20 Hz at $23^{\circ}C$. Results: The E' and E" increased with increasing frequency and showed differences in magnitude between brands. The $E^{*}s$ of composites at ${\omega}{\;}={\;}2{\;}Hz$, normalized to that of Z100, were 2.16 (Z250), 4,80 (P60) and 25.21 (SureFil). The magnitudes and patterns of the change of $tan{\delta}$ of composites with increasing frequency were significantly different between brands. The relationships between the complex modulus $E^{*}$, the phase angle ${\delta}$ and the frequency \omega were represented by frequency domain phasor form, $E^{*}{\;}(\omega){\;}={\;}E^{*}e^{i{\delta}}{\;}={\;}E^{*}{\angle}{\delta}$. Conclusions: The viscoelasticity of composites that influences handling characteristics is significant different between brands, The VOR is a relatively simple device for dynamic, mechanical analysis of high viscous dental composites. The locus of frequency domain phasor plots in a complex plane is a valuable method of representing the viscoelastic properties of composites.

The Dielertric and Piezoelectric Properties of PZT-PCNS Piezoelectric Ceramics with Zr/Ti Mole Ratio (Zr/Ti 몰비에 따른 PZT-PCNS 압전 세라믹의 압전 및 유전 특성)

  • Lee, S.Y.;Lee, Y.H.;Lee, M.J.;Lee, J.S.;Lim, K.J.
    • Proceedings of the KIEE Conference
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    • 2001.11a
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    • pp.100-102
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    • 2001
  • In this paper, the piezoelectric and dielectric properties of $Pb(Zr_xTi_{1-x)O_3$ - $Pb(Co_{1/3}Nb_{1/3})O_3)$ piezoelectric ceramics have been investigated as a function of Zr/Ti mole ratio. From the results, when Zr/Ti mole ratio is 49/51, electromechanical coupling coefficient($k_p$), piezoelectric strain constant($d_{33}$) mechanical quality factor($Q_m$), and Permittivity(${{\varepsilon}_{33}}^T/{\varepsilon}_0$) is 64[%], 469[PC/N], 360 and 2000, respectively. Morphotropic Phase Boundary is Zr/Ti mole ratio(49/51) from XRD analysis. Also. From SEM observation, when sintering temperature is 1150[$^{\circ}C$], grain size is about $1{\sim}2[{\mu}m]$ and maximum sintering density is 7.85[$g/cm^3$].

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