• Korean Journal of Environmental Biology
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• v.30 no.2
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• pp.77-89
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• 2012

With the advent of the genomics era powered by DNA sequencing technologies, life science is being transformed significantly and biological research and development have been accelerated. Environmental biology concerns the relationships among living organisms and their natural environment, which constitute the global biogeochemical cycle. As sustainability of the ecosystems depends on biodiversity, examining the structure and dynamics of the biotic constituents and fully grasping their genetic and metabolic capabilities are pivotal. The high-speed high-throughput next-generation sequencing can be applied to barcoding organisms either thriving or endangered and to decoding the whole genome information. Furthermore, diversity and the full gene complement of a microbial community can be elucidated and monitored through metagenomic approaches. With regard to human welfare, microbiomes of various human habitats such as gut, skin, mouth, stomach, and vagina, have been and are being scrutinized. To keep pace with the rapid increase of the sequencing capacity, various bioinformatic algorithms and software tools that even utilize supercomputers and cloud computing are being developed for processing and storage of massive data sets. Environmental genomics will be the major force in understanding the structure and function of ecosystems in nature as well as preserving, remediating, and bioprospecting them.

• Journal of Dental Rehabilitation and Applied Science
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• v.38 no.1
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• pp.60-68
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• 2022

A patient with severe periodontitis has causative factors that cause pathological tooth movement, the occlusion is disintegrated, and the vicious cycle of worsening periodontitis is repeated. In particular, when pathological tooth movement occurs in the maxillary anterior region, the patient has an aesthetic sense of atrophy, and the quality of life was reduced. Therefore, when orthodontic treatment was added to patients with severe periodontitis, it promotes the formation of new bone, reduces periodontal cysts, and obtains clinical attachment, which leads to favorable results in prosthetic restoration, thereby enabling ideal occlusion, function and aesthetics. Periodontal treatment, orthodontic treatment, natural tooth restoration, and implant prosthesis were planned for patients with pathological tooth movement in the anterior region due to loss of occlusal support in the posterior region. As a result, an ideal restoration space was secured, a stable restoration of occlusal contact was formed, and the maxillary anterior teeth were aesthetically improved.

• Journal of Korean Society for Quality Management
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• v.30 no.3
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• pp.203-236
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• 2002

Environmental Performance Evaluation(EPE) is a key process of Corporate Environmental Management. This paper presents the results of an empirical survey on the status of current practices in EPE of Korean firms. Based on a corporate environmental management(CEM) model, which is initially developed by Hibbitt and Kamp-Roelands(2001) and modified in terms of EPE, the survey is peformed on the population of Korean firms, which are composed of firms certified as "environmentally friendly" by Korean government and/or certified under Is014001, and compares its results with those of Europe's. Although the relatively low response rate and some methodological limitations makes us be cautious about the interpretation, the results shows many interesting aspects of the current states of Korean firms' EPE practices. That is, the levels of EPE implementation in the environmentally-leading companies of Korea are almost the same as that of European companies, I. e., in the-final-part-of-developing-stage (3rd stage) level of the CEM model. It is also shown that as In Europe's case, Korean firms are also moving slower in external relationships than in internal control and management, are more developed in the parameters like environmental policy, Internal control, Information system, which are requirements of certification under Is014001, than in parameters like life cycle analysis and full cost accounting, which requires more research efforts, etc.orts, etc.

• Journal of Industrial Technology
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• v.24 no.A
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• pp.215-226
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• 2004

A dynamic reliability model which can take into account the time history of loading sequences may be applied to the analyses of the hydraulic stability of armor units on rubble-mound breakwaters. All the parameters related to the stability of structures have been considered to be constants in the deterministic model until now. Thus, it is impossible to study the effects of some uncertainties of the related random variables on the stability of structures. In this paper, the dynamic reliability model can be developed by POT(Peak Over Threshold) method in order to take into account the time history of loading sequences and to investigate the temporal behaviors of stability of structure with its loading history. Finally, it is confirmed that the results of dynamic reliability model agree with straight- forwardly those of AFDA(Approximate Full Distribution Approach) of the static reliability model for the same input conditions. In addition, the temporal behaviors of probability of failure can be studied by the dynamic reliability model developed to analyze the hydraulic stability of armor units on rubble-mound breakwaters. Therefore, the present results may be useful for the management of repair and maintenance over the whole life cycle of structure.

• Parasites, Hosts and Diseases
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• v.55 no.3
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• pp.255-267
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• 2017

Malaria is an infectious disease affecting humans, which is transmitted by the bite of Anopheles mosquitoes harboring sporozoites of parasitic protozoans belonging to the genus Plasmodium. Despite past achievements to control the protozoan disease, malaria still remains a significant health threat up to now. In this study, we cloned and characterized the full-unit Plasmodium yoelii genes encoding merozoite surface protein 1 (MSP1), circumsporozoite protein (CSP), and Duffy-binding protein (DBP), each of which can be applied for investigations to obtain potent protective vaccines in the rodent malaria model, due to their specific expression patterns during the parasite life cycle. Recombinant fragments corresponding to the middle and C-terminal regions of PyMSP1 and PyCSP, respectively, displayed strong reactivity against P. yoelii-infected mice sera. Specific native antigens invoking strong humoral immune response during the primary and secondary infections of P. yoelii were also abundantly detected in experimental ICR mice. The low or negligible parasitemia observed in the secondary infected mice was likely to result from the neutralizing action of the protective antibodies. Identification of these antigenic proteins might provide the necessary information and means to characterize additional vaccine candidate antigens, selected solely on their ability to produce the protective antibodies.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.8
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• pp.996-1008
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• 1997

This paper describes a methodology and results for the analysis of a small steam injected gas turbine cogeneration system. A performance analysis program for the gas turbine engine is utilized with modifications required for the model of steam injection and the heat recovery steam generator (HRSG). The object of simulation is a simple cycle gas turbine engine under development which adopts a centrifugal compressor. The analysis is based on the off-design operation of the gas turbine and the compressor performance map is utilized. Analyses are carried out with the injection ratio as the main parameter. The effect of steam injection on the power and efficiency of gas turbine and cogeneration capacity is investigated. Also presented is the variation in the main operating parameters inside the HRSG. Remarkable reduction in NOx generation by steam injection is confirmed. In addition, it is observed that for the 100% power operation the temperature of the cooled first nozzle blade decreases by 100.deg. C at full steam injection, which seems to have a favorable effect on the engine life time.

• Proceedings of the Safety Management and Science Conference
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• 2002.11a
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• pp.227-232
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• 2002

Enormous flocks by the reduced life cycle of products caused by the technological innovation if later 20 century, development of new materials and diversified demands of customers appeared as the pressing element causing the trouble in management of companies, and when considering the logistic costs that are imposed to companies in terms of function, the costs related to the stock topped the list of costs, followed by the transportation ones, and for pallet pool system, inventory of stocks is very difficult by the number of companies. Reducing the logistic cost may be accomplished by numbers of logistic management methods, but the most fundamental and essential one is the accomplishment of the consistent pallet system that is the core of unit load system, and the purpose of consistent pallet system is the treatment of logistic functions such as transportation, storage and unloading with consistent pallet system, and increasing the turnover ratio is required for the improvement of the system. As the turnover ratios is increased, more pallets will be used so, numbers of empty pallets will be increased accordingly by returning the pallet. Therefore, in this study, we will establish the effective stock management system by comparing with the other existing stock management system after looking at the concept and examples of pallet full system in order to resolved this kind of problem.

• Journal of the Korea Safety Management & Science
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• v.5 no.1
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• pp.33-43
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• 2003

Enormous stocks by the reduced life cycle of products caused by the technological innovation in later 20 century, development of new materials and diversified demands of customers appeared as the pressing element causing the trouble in management of companies, and when considering the logistic costs that are imposed to companies in terms of function, the costs related to the stock topped the list of costs, followed by the transportation ones, and for pallet pool system, inventory of stocks is very difficult by the number of companies. Reducing the logistic cost may be accomplished by numbers of logistic management methods, but the most fundamental and essential one is the accomplishment of the consistent pallet system that is the core of unit load system, and the purpose of consistent pallet system is the treatment of logistic functions such as transportation, storage and unloading with consistent pallet system, and increasing the turnover ratio is required for the improvement of the system. As the turnover ratios is increased, more pallets will be used so, numbers of empty pallets will be increased accordingly by returning the pallet. Therefore, in this study, we will establish the effective stock management system by comparing with the other existing stock management system after looking at the concept and examples of pallet full system in order to resolved this kind of problem.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.1
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• pp.85-92
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• 2011

Main characteristic in railroad is the guided movement of the wheel by the track through a metal-to-metal contact, conferring to the rail vehicle a single degree of freedom. There are defects such as head check, shelling, corrugation, squats etc in surface of the rail by interface between the wheel and rail. These defects bring about reducing the life-cycle of rails and track components and increasing noises. In case of bad conditions, it is possible to happen to full-scale accident such as derailment. Recently, the track capacity has been increased for increasing speed and operation efficiency. So, maintenance and indirect cost have been increased. Currently, a coating method of rail construction is proposed by using the ceramics in Korea. Rails are used as the earth in electrical railroad systems. Currently traction return current is flowed through wheels of trains. In case of rails coated, problems are caused in the contact power between wheel and coating material of spray. In this paper, electric model is presented in the AT feeding method. In case of rails coated, electric model is presented. Also, standard resistance of the ceramic is demonstrated by contact power between wheel and coating material of spray.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2008.05a
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• pp.205-208
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• 2008

Generally, there are several types in rear suspension. The rear suspension of subframe type consisting of side member and front/rear cross member is widely used in a medium car and full car. In the small car case, the beam of tubular type without independent suspension system is used to reduce manufacturing cost. The optimized rear suspension of subframe type using hydroforming method has been developed in this study. In designing suspension, the driving stability and durability performance should be considered as an important factor. The stability is related to dynamic frequency and durability is connected with stress analysis of structure. We focus on increasing the stiffness of suspension and decreasing the maximum stress relating to durability cycle life. For making use of the merits of hydroforming which is possible to make the bead, tube expansion, and feeding in desiring position, several optimization design techniques such as shape, size, and topology optimization are proposed. This optimization scheme based on the sensitivity can provide distinguished performance improvement in using hydroforming. Through commercial software based on the finite element, the superiority of this design method is demonstrated.