• Journal of Microbiology and Biotechnology
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• v.26 no.8
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• pp.1358-1366
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• 2016

The purpose of the present study was to investigate the immune-enhancing activity of selenizing Codonopsis pilosula polysaccharide (sCPPS₅) in nonspecific immune response. In in vitro experiment, the results showed that sCPPS₅ could promote the phagocytic uptake, NO production, and TNF-α and IL-6 secretion of RAW264.7 cells. sCPPS₅ could also strongly increase the IκB-α degradation in the cytosol and the translocation of NF-κB p65 subunit into the nucleus of RAW264.7 cells. In the vivo experiment, sCPPS₅ at medium doses could significantly improve the phagocytic index of peritoneal macrophages and induce the secretion of TNF-α and IL-6. Moreover, the effect of sCPPS₅ was significantly better than Codonopsis pilosula polysaccharide (CPPS). These results indicated that selenylation modification could significantly enhance the immune-enhancing activity of CPPS in the nonspecific immune response.

• Proceedings of the KSEEG Conference
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• 2001.04a
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• pp.231-233
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• 2001

• Journal of Preventive Medicine and Public Health
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• v.47 no.5
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• pp.281-287
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• 2014

Objectives: In Fujian Province, China, gastric cancer is one of the leading causes of mortality among all malignant tumors. Nanjing county and Minqing county are located in inland Fujian and have similar general demographics. However, the adjusted mortality rate of gastric cancer in Minqing was found to be much higher than that in Nanjing. We sought to explore factors associated with this increased risk of gastric cancer between the two counties. Methods: We recruited 231 and 224 residents from Nanjing and Minqing, respectively, and analyzed differences between their dietary habits, Helicobacter pylori infection rates, and concentrations of serum pepsinogen I, pepsinogen II, gastrin-17, and ratio of pepsinogen I:II. Results: Subjects in Minqing had more first-degree relatives who had been diagnosed with upper gastrointestinal tumor, more unhealthy dietary habits, a higher Helicobacter pylori positive rate, and greater proportion of abnormal serum gastrin-17 than those in Nanjing did. Conclusions: The factors that differed between these two counties might indicate that residents in Minqing have a higher risk for developing gastric cancer than those in Nanjing do.

• The Journal of Asian Finance, Economics and Business
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• v.10 no.2
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• pp.213-222
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• 2023

This paper mainly studies the relationship between financial development, inbound tourism development, and economic growth rate in Fujian Province, China. This study uses the data of real GDP, foreign exchange income from international tourism, and financial interrelations ratio from 1994 to 2019. In the analysis process, the Johansen cointegration test is first used to analyze whether the three have a long-term equilibrium relationship. Then the vector error correction model is established to test the restrictive relationship among the three. Next, the Granger causality test assesses whether the three have a causal relationship. Finally, the contribution rate of the three is analyzed by variance decomposition. The above methods show the following conclusions: first, the three have a long-term equilibrium relationship. Secondly, in the short term, local economic growth is constrained by inbound tourism and financial development. Thirdly, there is a causal relationship between economic growth and inbound tourism in Fujian, while there is a unidirectional causal relationship between financial development and economic growth, financial development, and inbound tourism. Fourthly, the contribution rate of inbound tourism to economic growth fluctuations in Fujian is higher than that of financial development.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.3
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• pp.355-364
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• 2022

The effect of technological innovation on the high-quality development of the producer services industry depends on whether or not technical innovation efficiency plays a key role. This study looks at the impact of technological innovation and financial technology (fintech) on the development of high-quality producer services in Fujian Province from 2010 to 2019. The efficiency of technological innovation is measured using Data Envelopment Analysis (DEA) and the Malmquist productivity index. The mean overall innovation efficiency score is 0.639, meaning that Fujian accounts for 36.1% of resource utilization inefficiencies and that there are significant differences in technological innovation efficiency between cities. The findings show that high-quality producer services industries benefited from innovation efficiency, but that the influence of technological innovation efficiency is insignificant. This demonstrates that financial innovation has not been able to completely enhance the development level of the producer services industry. This may be due to the unreasonable output structure of technological innovation and the low industrial transformation rate of technological achievements. This study advocates that the R&D fund allocation structure be optimized. That technological innovation can improve the high-quality development of the producer services industry is a consensus within the academic community.

• Nutrition Research and Practice
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• v.9 no.2
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• pp.129-136
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• 2015

BACKGROUND/OBJECTIVES: A variety of immunomodulators can improve the efficacy of low-dose chemotherapeutics. Active hexose correlated compound (AHCC), a mushroom mycelia extract, has been shown to be a strong immunomodulator. Whether AHCC could enhance the antitumor effect of low-dose 5-fluorouracil (5-FU) via regulation of host immunity is unknown. MATERIALS/METHODS: In the current study Hepatoma 22 (H22) tumor-bearing mice were treated with PBS, 5-FU ($10mg{\cdot}kg^{-1}{\cdot}d^{-1}$, i.p), or AHCC ($360mg{\cdot}kg^{-1}{\cdot}d^{-1}$, i.g) plus 5-FU, respectively, for 5 d. $CD^{3+}$, $CD^{4+}$, $CD^{8+}$, and NK in peripheral blood were detected by flow cytometry. ALT, AST, BUN, and Cr levels were measured by biochemical assay. IL-2 and $TNF{\alpha}$ in serum were measured using the RIA kit and apoptosis of tumor was detected by TUNEL staining. Bax, Bcl-2, and TS protein levels were measured by immunohistochemical staining and mRNA level was evaluated by RT-PCR. RESULTS: Diet consumption and body weight showed that AHCC had no apparent toxicity. AHCC could reverse liver injury and myelosuppression induced by 5-FU (P < 0.05). Compared to mice treated with 5-FU, mice treated with AHCC plus 5-FU had higher thymus index, percentages of $CD^{3+}$, $CD^{4+}$, and NK cells (P < 0.01), and ratio of $CD^{4+}$/$CD^{8+}$ (P < 0.01) in peripheral blood. Radioimmunoassay showed that mice treated with AHCC plus 5-FU had the highest serum levels of IL-2 and $TNF{\alpha}$ compared with the vehicle group and 5-FU group. More importantly, the combination of AHCC and 5-FU produced a more potent antitumor effect (P < 0.05) and caused more severe apoptosis in tumor tissue (P < 0.05) compared with the 5-FU group. In addition, the combination of AHCC and 5-FU further up-regulated the expression of Bcl-2 associated X protein (Bax) (P < 0.01), while it down-regulated the expression of B cell lymphoma 2 (Bcl-2) (P < 0.01). CONCLUSIONS: These results support the claim that AHCC might be beneficial for cancer patients receiving chemotherapy.

• Journal of architectural history
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• v.30 no.1
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• pp.33-42
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• 2021

This paper analysed the architectural images on Pleasant Gathering of Leeum, Samsung museum of art, which has been assumed as a work of the Koryo dynasty. Through the comparison between the unique wooden structure at roof edge on the building images and real architectures, it found the buildings on the painting were from China Fujian(福建), not from Korea. It also analysed the color painting on buildings, trees, themes from previous famous paintings and dresses to confirm these images were came from the early period of the Ming dynasty. It is a very unique painting containing various information on the Fujian ancient architecture, but its architecture drawing is not as skillful as typical ancient Chinese paintings.

• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.1154-1162
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• 2019

China is undertaking an energy reform from fossil fuels to clean energy to accomplish $CO_2$ intensity (CI) reduction commitments. After hydropower, nuclear energy is potential based on breadthwise comparison with the world and analysis of government energy consumption (EC) plan. This paper establishes a CI energy policy response forecasting model based on national and provincial EC plans. This model is then applied in Fujian Province to predict its CI from 2016 to 2020. The result shows that CI declines at a range of 43%-53% compared to that in 2005 considering five conditions of economic growth in 2020. Furthermore, Fujian will achieve the national goals in advance because EC is controlled and nuclear energy ratio increased to 16.4% (the proportion of non-fossil in primary energy is 26.7%). Finally, the development of nuclear energy in China and the world are analyzed, and several policies for energy optimization and CI reduction are proposed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7741-7746
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• 2014

Although a number of studies have been conducted on the association between GSTM1 polymorphisms and lung cancer in China, this association remains elusive and controversial. To clarify the effects of GSTM1 polymorphisms on the risk of lung cancer, a meta-analysis was performed in the Chinese population. Related studies were identified from PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) up to 5th April 2014. A total of 45 articles (47 studies) including 6,623 cases and 7,865 controls were involved in this meta-analysis. Overall, a significant association (OR = 1.45, 95%CI: 1.32-1.60) was found between the null GSTM1 and lung cancer risk when all studies in Chinese population pooled into the meta-analysis. In subgroup analyses stratified by quality score, geographic area and source of controls, the same results were observed under all the models. This meta-analysis showed that the null GSTM1 may be a potential biomarker for lung cancer risk in Chinese, but further studies with gene-gene and gene-environment interactions are required for definite conclusions.

• Journal of the Korean Institute of Rural Architecture
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• v.15 no.1
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• pp.55-62
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• 2013

This study is to solve this problem, as the center of China in the east started the investigation. In eastern China : rapid economic growth, Population is concentrated, Migration of rural population to large cities. So I chose this as the survey area. Including central and eastern China : Shandong Province, Jiangsu Province, Zhejiang Province, Fujian Province, Anhui Province, Jiangxi Province and Shanghai. Research studies as a whole is divided into three main parts: The first is the basic situation of rural housing survey. Including : housing age, wall materials, roof form, house equipment, housing composition, etc. Then home for further investigation of these houses exist in the main room on the device and the joint space problems. Finally, to address these issues, the survey specifically classified as a pure compound the family home and two cases. Through interviews, to understand the survey requirements for housing improvement. Finally, comparison summary, conclusion.