• Journal of Korean Academy of Nursing
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• v.39 no.1
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• pp.107-115
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• 2009

Purpose: The purpose of this study was to identify the effects of an exercise program on frontal lobe cognitive function in seniors. Methods: The participants were 42 seniors using a health center in Seoul (experimental group) and 28 seniors using a facility for elders in Seoul (control group). The exercise program was carried out for 16 weeks from April to August 2007. The frontal lobe cognitive function, which includes short term memory, attention, immediate memory, delayed memory, verbal fluency and motor function, was measured by the Digit Span Forward test, Trail Making test, Immediate recall words test, Delayed recall words, Controlled oral word association test and Finger tapping test. The collected data were analyzed by Fisher's exact test, Chi-square, t-test, and ANCOVA using the SAS program. Results: The major findings of this study were as follows: Attention (p=.009), immediate memory (p=.005), delayed memory (p=.009), and verbal fluency (p=.004) improved after the exercise program. Conclusion: In this study, the exercise program was effective in improving frontal lobe cognitive function in elders. So it provides basic information for further nursing education on exercise programs which will be effective for prevention of early cognitive function decline in normally aging elders.

• Korean Journal of Biological Psychiatry
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• v.9 no.2
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• pp.95-102
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• 2002

Objectives:Abnormalities in the frontal lobe have been consistently suggested in the pathophysiology of depression. The purpose of this review is to discuss the relationship between the frontal lobe and depression. Methods:Recent researches on the frontal lobe in depression were reviewed and abnormalities in this region were considered within the context of modern functional neuroanatomy. Results:This paper reviewed evidence strongly implicating the frontal lobe as a key brain structure in depression. Conclusion:Taken together, these abnormalities in the function of the frontal lobe implicate interconnected neural circuits in depression and offer suggestions for the themes of future research and treatment. Further research is needed to investigate the association between emotion and the brain in the paradigm of "affective neuroscience".

• Anxiety and mood
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• v.8 no.1
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• pp.31-40
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• 2012

Objective : The purpose of this study was to analyze the correlation between symptom severity and neurocognitive factors in traumatic head injury patients. In addition, the effect of frontal lobe damage on these parameters was examined. Methods : We selected 18 patients who had brain damage for the moderate to severe traumatic brain injury (MSTBI) group, and 17 patients who met the diagnostic criteria for post-traumatic stress disorder (PTSD) without the finding of brain damage for the comparison group. For the evaluation of neurocognitive function, K-WAIS, Rey-Kim Memory Test, K-FENT, WCST, and MMPI-2 were used. Results : The results of the comparison (using the malingering scale) revealed that the values of PDS and PK, which express the severity of symptoms, and the values of the validity scale F, F (B), and F (P) were significantly higher in the overly-expressed group. F (B) in overly-expressed group and PK, Pt, and Sc in the properly-expressed group had significant correlation with the severity of symptoms. F (B), S, and Stroop error inhibition in PTSD, and PK, Pt, Sc, and MQ in MSTBI had significant correlation with the severity of symptoms. The results of the comparison based on the finding of frontal lobe damage revealed that PDS, EIQ, and MQ ware significantly higher in the group without brain damage. Conclusions : It was revealed that each neurocognitive factor was correlated with the severity of symptoms. There was a decrease in complaints or symptoms reported by the frontal lobe injury group, and this is believed to be due to degenerative change in the personality and emotional functioning of these patients following frontal lobe damage.

• The Journal of Korean Physical Therapy
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• v.15 no.3
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• pp.295-345
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• 2003

This study investigated activation of cerebral cortex in patients with hemiplegia that was caused by neural damage. Key-point control movement therapy of Bobath was performed for 9 weeks in 3 subjects with hemiplegia and fMRI was used to compare and analyze activated degree of cerebral cortex in these subjects. fMRI was conducted using the blood oxygen level-dependent(BOLD) technique at 3.0T MR scanner with a standard head coil. The motor activation task consisted of finger flexion-extension exercise in six cycles(one half-cycles = 8 scans = $3\;sec{\times}\;8\;=\;24\;sec$). Subjects performed this task according to visual stimulus that sign of right hand or left hand twinkled(500ms on, 500ms off). After mapping activation of cerebral motor cortex on hand motor function, below results were obtained. 1. Activation decreased in primary motor area, whereas it increased in supplementary motor area and visual association area(p<.001). 2. Activation was observed in bilateral medial frontal gyrus, middle frontal gyrus of left cerebrum, inferior frontal gyrus, inter-hemispheric, fusiform gyrus of right cerebrum, superior parietal lobule of parietal lobe and precuneus in subjedt 1, parahippocampal gyrus of limbic lobe and cingulate gyrus in subject 2, and inferior frontal gyrus of right frontal lobe, middle frontal gyrus, and inferior parietal lobule of left cerebrum in subject 3 (p<.001). 3. Activation cluster extended in declive of right cellebellum posterior lobe in subject 1, culmen of anterior lobe and declive of posterior lobe in subject 2, and dentate gyrus of anterior lobe, culmen and tuber of posterior lobe in subject 3 (p<.001). In conclusion, these data showed that Key-point control movement therapy of Bobath after stroke affect cerebral cortex activation by increasing efficiency of cortical networks. Therefore mapping of brain neural network activation is useful for plasticity and reorganization of cerebral cortex and cortico-spinal tract of motor recovery mechanisms after stroke.

• Journal of International Academy of Physical Therapy Research
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• v.10 no.1
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• pp.1700-1705
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• 2019

Background: Mild cognitive impairment (MCI) is also called as aging related memory damage. Decreased cognitive function due to aging is known to be associated with the frontal lobe. Alpha wave is generated in the dominance in the frontal lobe or a wide range of regions in the brain, it should be doubted that the brain function might be degraded. Objective: To determine the effect of sensory stimulation type on learning and brain activity pattern of elderly persons with MCI. Design: Randomized Controlled Trial (single blind) Methods: Twenty elderly persons aged more than 65 with MCI were randonmized to simultaneous visual/auditory stimulation group (SVASG) and or auditory stimulation group (ASG). Ten peoples were assigned to each group and lectroencephalogram test was performed to individuals. In the electroencephalogram test, electroencephalography of prior to sensory stimulation, and during sensory stimulation were measured to compare brain activity pattern according to the study groups and measurement period. Results: The relative alpha power due to a sensory stimulation type showed that the SVASG significantly decreased in the left frontal lobe and the left parietal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). The relative beta power due to a sensory stimulation type showed that the SVASG significantly increased in the left and right frontal lobes, the left and right parietal lobes, and the left temporal lobe statistically compared to those of the ASG while sensory stimulation was given (p<.05). Conclusions: Electroencephalographic analysis showed that the type of sensory stimulation can affect the brain activity pattern. However, the effects were not studied that which brain activity pattern help to improved cognitive function of elderly persons with mild cognitive impairment.

• Therapeutic Science for Rehabilitation
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• v.6 no.2
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• pp.71-83
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• 2017

Objective: This study was to develop and verify the effects of the exercise-cognitive combined dual-task training program on cognitive function and depression of the elderly with mild cognitive impairment(MCI). Methods: The subjects were randomly assigned to the exercise-cognitive combined dual-task training group(n=32) or single-task training group(n=31). To identify the effects on cognitive function, general cognitive function, frontal lobe function, and attention/working memory were measured. Depression was evaluated using Korean version of Geriatric Depression Scale. The outcome measurements were performed before and after the 8 weeks of intervention(2 days per week). Results: After 8 weeks, general cognitive function, frontal cognitive function, attention/working memory function, depression of the dual-task training group were significantly increased than those of the single-task training group(p<0.05). Conclusion: The results indicated that an exercise-cognitive combined dual-task training for MCI was effective in improving general cognitive function, frontal /executive function, attention/working memory function and reducing depression.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.219-227
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• 2019

The purpose of this study is to investigate the relationship between self - integration and frontal cognitive function in the welfare center users. The data were collected on January 18-30, 2018. 120 people in the M city, has participated in more than 65 years older. data were analyzed using frequency, mean and standard deviation, t-test, ANOVAs, and Pearson's correlation coefficient and multiple regression analysis. The results of this study showed that current satisfaction of welfare center users is statistically different from 'attitude toward life', 'acceptance of lifetime', 'satisfaction of present life' of ego integrity. Self - integration sense showed 28.3% explanatory power in current life. Effect of prefrontal cognitive function in accordance with the partner showed a 16.1% explanatory power This study suggests the necessity of policy and program development for the elderly community life to improve self - integration and frontal cognitive function in old age.

• International Journal of Advanced Culture Technology
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• v.9 no.2
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• pp.18-31
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• 2021

The purpose of the present study was to present evidence for driving interventions for the elderly by conducting programs that can improve visual perception and cognitive function in a driving simulator for elderly drivers and analyse their effects. Three elderly subjects who were 65 years or older, did not have physical and cognitive impairments, and were able to drive themselves participated in the present study. A total of 12 intervention sessions, of which subjects participated in 10 sessions of nine different visual perception and cognitive function programs available in a driving simulator, were conducted and pre- and post-program assessments were conducted (two assessments in total). The assessments included the evaluation of visual perception, frontal lobe function, concentration, safe driving behaviour, and self-efficacy. The results showed positive effects of the driving simulator program on the visual perception, frontal lobe function, concentration, safe driving behaviour, and self-efficacy of all subjects. Changes in the simulator results showed remarkable improvement in the response evaluation, judgment evaluation, and predictive power evaluation, but showed difficulties in interference tasks and depth perception in common. The results showed positive effects of driving simulator training on the driving ability of the elderly, and consistent provision of such training is expected to improve the quality of life of the elderly by securing the safety of driving and actively supporting social participation.

• Sleep Medicine and Psychophysiology
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• v.4 no.1
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• pp.39-48
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• 1997

Memory disorder is the most consistent neuropsychological finding in schizophrenia and seems to be a stable trait in it. It is suggested that memory dysfunction found in patients with schizophrenia is primary to biological abnormalities, not secondary to attention deficits they have. Although temporal lobe structures including hippocampus and thalamus have traditionally been thought to be implicated regions for memory disorder in schizophrenia, recent studies indicate the possibility of abnormalities in the frontal lobe and the neural circuits between brain regions. Advanced research methods such as functional imaging technique are expected to produce more detailed informations about memory function in schizophrenia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.9
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• pp.5495-5501
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• 2014

Individuals with a left frontal brain injury show significant impairments in their speech ability. The aims of the present study were (1) to assess and compare the ability of speech acts comprehension and executive function between individuals with a left frontal brain injury and normal individuals, and (2) to investigate the correlation of speech act comprehension ability factors. The study's subjects were 18 individuals with a left frontal brain injury and 18 normal control adults of the same age, gender, and educational age. The following results were obtained. First, the group of individuals with a left frontal brain injury had lower speech act comprehension, executive function than the normal control group. Second, the speech act comprehension ability of the individuals with a left frontal brain injury showed a high correlation with the executive function.