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Association of the A-G Polymorphism in Porcine Adiponectin Gene with Fat Deposition and Carcass Traits

  • Dai, L.H.;Xiong, Y.Z.;Deng, C.Y.;Jiang, S.W.;Zuo, B.;Zheng, R.;Li, F.E.;Lei, M.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.6
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    • pp.779-783
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    • 2006
  • The adiponectin gene is known to be involved in the regulation of energy homeostasis involving food intake, carbohydrate and lipid metabolism. Human adiponectin gene polymorphisms have been recently reported to be associated with obesity, insulin sensitivity and the risk of type 2 diabetes. The present study was carried out to investigate the porcine adiponectin gene as a candidate gene for fat deposition and carcass traits. A mutation of A178G of the porcine adiponectin gene that resulted in substitution of the amino acid Isoleucine to Valine was identified. AcyI PCR-RFLP was used to detect the polymorphism of the genotypes in five different pig populations (Large White, Landrace, Duroc, Chinese breeds Meishan and Qingping). The A allele frequency was significantly higher among subjects from Chinsese lard type breeds, while the G allele was the only one present in those from Western lean type breeds. To determine if there was an association of the polymorphism with phenotypic variation, the mutation was tested in 267 pigs of the "Large $White{\times}Meishan$" F2 resource population. The results of association analyses showed significant associations of the genotypes with fat deposition and carcass traits. Allele G was significantly associated with increase in loin eye height, loin eye area and lean meat percentage and bone percentage, and decrease in fat mean percentage, ratio of lean to fat, shoulder fat thickness, 6-7 rib fat thickness, thorax-waist fat thickness and buttock fat thickness. The substitution of A178G (Ile60Val) happened to be located at amino acid 60 in the collagenous domain of porcine adiponectin which might affect the association into higher-order structures, and accordingly affect the posttranslational modifications and optimal biological activity of the multimeric forms. The identified functional polymorphism provides new evidence of adiponectin as an important candidate gene affecting fat deposition and carcass traits in pigs.

A Comparative Analysis on Keywords of International and Korean Journals in Library and Information Science (국내외 문헌정보학 저널의 키워드 비교 분석)

  • Kim, Eungi
    • Journal of Korean Library and Information Science Society
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    • v.48 no.1
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    • pp.207-225
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    • 2017
  • The aim of this study was to discover various Library and Information Science (LIS) research areas by examining similarities and differences between LIS journals in terms of keyword characteristics. To conduct this study, for the years from 2004 to 2016, the keywords of 6 international journals were downloaded from Scopus database (http://www.scopus.com), and the keywords of 4 Korean journals were downloaded from the RISS database (http://www.riss.co.kr). The characteristics of keywords were investigated by examining frequently used keywords and frequently used distinctive keywords pertaining to international and Korean journals. The distinctive keywords are referred to as the keywords that appear in one domain but not in another. The result of this study indicated the following: a) a frequency analysis of the keywords showed major research themes and unique traits concerning Korea. b) In general, the keywords used in Korean journals frequently reflected the library as a major subject area of research, while keywords used in international journals reflected bibliometrics and information retrieval as major subject areas of research. c) The overarching themes of each created dataset were clearly noticeable in frequently used distinctive keywords. d) Some keywords were bound by a nation or by a region due to their scope of usage. The important implication of this study is that both most frequently used keywords and most frequently used distinctive keywords seemed to adequately represent the LIS subject areas.

Investigation of PCR-RFLPs within Major Histocompatibility Complex B-G Genes Using Two Restriction Enzymes in Eight Breeds of Chinese Indigenous Chickens

  • Xu, R.F.;Li, K.;Chen, G.H.;Qiang, B.Y.Z.;Mo, D.L.;Fan, B.;Li, C.C.;Yu, M.;Zhu, M.J.;Xiong, T.A.;Liu, Bang
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.7
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    • pp.942-948
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    • 2005
  • New polymorphism of major histocompatibility complex B-G genes was investigated by amplification and digestion of a 401bp fragment including intron 1 and exon 2 using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique with two restriction enzymes of Msp I and Tas I in eight breeds of Chinese indigenous chickens and one exotic breed. In the fragment region of the gene, three novel single nucleotide polymorphisms (SNPs) were detected at the two restriction sites. We found the transition of two nucleotides of A294G and T295C occurred at Tas I restriction site, and consequently led to a non-synonymous substitution of asparagine into serine at position 54 within the deduced amino acid sequence of immunoglobulin variable-region-like domain encoded by the exon 2 of B-G gene. It was observed at rare frequency that a single mutation of A294G occurring at the site, also caused an identical substitution of amino acid, asparagine 54-to-serine, to that we described previously. And the transversion of G319C at Msp I site led to a non-synonymous substitution, glutamine 62-to-histidine. The new alleles and allele frequencies identified by the PCR-RFLP method with the two enzymes were characterized, of which the allele A and B frequencies at Msp I and Tas I loci were given disequilibrium distribution either in the eight Chinese local breeds or in the exotic breed. By comparison, allele A at Msp I locus tended to be dominant, while, the allele B at Tas I locus tended to be dominant in all of the breeds analyzed. In Tibetan chickens, the preliminary association analysis revealed that no significant difference was observed between the different genotypes identified at the Msp I and Tas I loci and the laying performance traits, respectively.

An Implementation of Automatic Genre Classification System for Korean Traditional Music (한국 전통음악 (국악)에 대한 자동 장르 분류 시스템 구현)

  • Lee Kang-Kyu;Yoon Won-Jung;Park Kyu-Sik
    • The Journal of the Acoustical Society of Korea
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    • v.24 no.1
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    • pp.29-37
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    • 2005
  • This paper proposes an automatic genre classification system for Korean traditional music. The Proposed system accepts and classifies queried input music as one of the six musical genres such as Royal Shrine Music, Classcal Chamber Music, Folk Song, Folk Music, Buddhist Music, Shamanist Music based on music contents. In general, content-based music genre classification consists of two stages - music feature vector extraction and Pattern classification. For feature extraction. the system extracts 58 dimensional feature vectors including spectral centroid, spectral rolloff and spectral flux based on STFT and also the coefficient domain features such as LPC, MFCC, and then these features are further optimized using SFS method. For Pattern or genre classification, k-NN, Gaussian, GMM and SVM algorithms are considered. In addition, the proposed system adopts MFC method to settle down the uncertainty problem of the system performance due to the different query Patterns (or portions). From the experimental results. we verify the successful genre classification performance over $97{\%}$ for both the k-NN and SVM classifier, however SVM classifier provides almost three times faster classification performance than the k-NN.

Design and Fabrication of Miniaturized Dual-bandpass filter Using Rectangular ring resonator and Interdigital capacitive feeding-structure (Rectangular Ring 공진기와 Interdigital Capacitive 급전구조를 이용한 소형화된 이중대역통과필터의 설계 및 제작)

  • Yoon, Hyun-Soo;Kang, Sang-Rok;Choi, Byoung-Ha
    • Journal of Navigation and Port Research
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    • v.31 no.5 s.121
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    • pp.415-420
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    • 2007
  • In this paper, we have designed and fabricated a new type of bandpass-filter that used rectangular ring and interdigital capacitive feeding-structure. The filter is applied the modified rectangular ring and interdigital capacitive feeding-structure in patch, which reduce rho size of filter and IEEE 802. 11 correspond to wireless LAN domain(2.45GHz and 5.2GHz) for operating. As a result, the design and fabrication process of the filter become simple and the size of it is reduced more than 60% compared with RF filter are available conventional PEMBF(Parallel Edge-coupled Microstrip Bandpass Filter) of accounted circuit by minimum stage, measurement result of fabricated filter, center frequence is down 2.408GHz and 5.075GHz. input return loss is -39.169dB at 2.408GHz, -40.922dB at 5.075GHz. insertion loss is -0.437dB at 2.408GHz, -1.669dB at 5.075GHz.

CoP operational characteristics and CoP performance in Government Research Institutes (국가연구개발조직에서의 CoP 운영특성과 CoP 성과와의 관계 연구)

  • Choi, Jong-In;Hong, Kil-Pyo;Jang, Seung-Kwon
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.6 no.3
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    • pp.177-191
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    • 2011
  • A community of practice (CoP) is a group of people who share an interest, a craft, and/or a profession. The group can evolve naturally because of the members' common interest in a particular domain or area, or it can be created specifically with the goal of gaining knowledge related to their field. It is through the process of sharing information and experiences with the group that the members learn from each other, and have an opportunity to develop themselves personally and professionally. This study focus on the 151 researchers of four government research institutes(GRIs) and research empirically an operational characteristics and performanceof CoP. Results show that characteristics like a new member increase, external linkage oriented- challenging climate, diversity oriented- autonomous climate affect a CoP performance. But external factors such as the number of participants, meeting frequency are not related with the CoP performance.

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Preparation and Electrochemical Characteristics of Polymer Electrolyte Based on MCM-41/Poly(ethylene oxide) Composites (MCM-41/Po1y(ethylene oxide) 복합체로 구성된 고분자 전해질의 제조와 전기화학적 특성)

  • Kim Seok;Kang Jin-Young;Lee Sung-Goo;Lee Jae-Rook;Park Soo-Jin
    • Polymer(Korea)
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    • v.29 no.4
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    • pp.403-407
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    • 2005
  • In this work, the solid polymer electrolyte (SPE) composites, which are composed of poly(ethylene oxide) (PEO), mesoporous mobil crystalline material-41 (MCM-41), and lithium salt, are prepared in order to investigate the influence of MCM-41 contents on the ionic conductivity of the composites. The crystallinity of the SPE composites was evaluated using differential scanning calorimeter (DSC) and X-ray diffraction (XRD). The ionic conductivity of the SPE composites was measured by the frequency response analyzer (FRA). As a result, the addition of MCM-41 into the polymeric mixture prohibited the growth of PEO crystalline domain due to the mesoporous structures of the MCM-41. The $P(EO)_{16}LiClO_4$/MCM-41 electrolytes show an increased ion conductivity as a function of MCM-41 content up to 8 $wt\%$ and a slightly decreased conductivity over 8 $wt\%$. These ion conductivity characteristics are dependent on a change of polymer crystallinity in the presence of MCM-41 system.

A Power Control-Based MF-TDMA Resource Allocation Scheme for Next Generation Military Satellite Communication Systems (차기 군 위성통신망 체계에서 이기종 단말 운용을 고려한 전력제어 기반 MF-TDMA 자원할당 기법)

  • Woo, Soon;Park, Hyung-Won;Lee, Ho-Sub;Yoo, Youn-Sang;Jung, Byung-Gi
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37C no.11
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    • pp.1138-1147
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    • 2012
  • In this paper, an efficient power control based MF-TDMA resource allocation scheme is proposed for next generation military satellite communication systems. The proposed scheme has the flexibility is used to support heterogeneous terminals with differ in transmission capabilities. The method can be divided into two parts : burst size calculation and burst structure determination. At first, we estimate the link budget taken into account a dynamic satellite link state variation. Then, applicable ACM level and burst size is chosen. In burst structure determination phase, we reorganize the burst structure in time-frequency domain by controlling limited power, bandwidth, time resources. In particular, we compensate the power spectral density among different terminals to integrate them in same transponder, Furthermore, we increase the packing efficiency by controlling the ACM level of the burst in applicable power spectral density range. Simulation results show that the method increase the spectral efficiency and burst packing efficiency. In addition, slot allocation rejection ratio is successfully reduced.

Turbo FLASH NRI Using Optimized Flip Angle Pattern: Application to Inversion-Recovery T1-Weighted Imaging (최적화된 Flip Angle Pattern을 사용한 Turbo FLASH MRI: Inversion-Recovery T1-Weighted Imaging에의 응용)

  • Oh, C.H.;Choi, H.J.;Yang, Y.J.;Lee, D.R.;Ryu, Y.C.;Hyun, J.H.;Kim, S.R.;Yi, Y.;Jung, K.J.;Ahn, C.B.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.55-56
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    • 1998
  • The 3-D Fast Gradient Echo (Turbo FLASH, Turbo Fast Low Angle Shot) sequence is optimized to achieve a good T1 contrast using variable excitation flip angles. In Turbo FLASH sequence, depending on the contrast preparation scheme, various types of image contrast can be established. While proton density contrast is obtained when using a short repetition time with a short echo time and small flip angles, T1 or T2 weighting can be obtained with proper contrast preparation sequences applied before the above proton density Turbo FLASH sequence. To maximize the contrast to noise ratio while retaining a sharp impulse response (smooth frequency domain response), the excitation flip-angle pattern is optimized through simulation and experiments. The TI (the delay after the preparation sequence which is a 180 degree inversion RF pulse in the IR T1 weighted imaging case), TD (the delay time between the Turbo FLASH sequence and the next preparation), and TR are also optimized fur the best image quality. The proposed 3-D Turbo FLASH provides $1mm\times1mm\times1.5mm$ high resolution images within a reasonable 5-8 minutes of imaging time. The proposed imaging sequence has been implemented in a Medison's Magnum 1.0T system and verified through simulations as well as human volunteer imaging. The experimental results show the utility of the proposed method.

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Modeling of Elastodynamic Problems in Finite Solid Media (유한 고체내 탄성동역학 문제의 모델링)

  • Cho, Youn-Ho
    • Journal of the Korean Society for Nondestructive Testing
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    • v.20 no.2
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    • pp.138-149
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    • 2000
  • Various modeling techniques for ultrasonic wave propagation and scattering problems in finite solid media are presented. Elastodynamic boundary value problems in inhomogeneous multi-layered plate-like structures are set up for modal analysis of guided wave propagation and numerically solved to obtain dispersion curves which show propagation characteristics of guided waves. As a powerful modeling tool to overcome such numerical difficulties in wave scattering problems as the geometrical complexity and mode conversion, the Boundary Element Method(BEM) is introduced and is combined with the normal mode expansion technique to develop the hybrid BEM, an efficient technique for modeling multi mode conversion of guided wave scattering problems. Time dependent wave forms are obtained through the inverse Fourier transformation of the numerical solutions in the frequency domain. 3D BEM program development is underway to model more practical ultrasonic wave signals. Some encouraging numerical results have recently been obtained in comparison with the analytical solutions for wave propagation in a bar subjected to time harmonic longitudinal excitation. It is expected that the presented modeling techniques for elastic wave propagation and scattering can be applied to establish quantitative nondestructive evaluation techniques in various ways.

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