• Journal of Yeungnam Medical Science
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• 제38권2호
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• pp.127-135
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• 2021

Background: Dialysis patients are prone to having disabilities. We aimed to evaluate the association between disability and various clinical outcomes in Korean dialysis patients. Methods: This study consisted of 1,615 dialysis patients from 27 centers. We evaluated disability by using four questions on the activities of daily living (ADLs) concerning whether help was needed for feeding, dressing/undressing, getting in/out of bed, or taking a bath/shower. We divided the patients into three groups: no disability (Non-D, none of the four ADL domains required help; n=1,312), mild disability (Mild-D, one ADL domain required some/full help; n=163), or moderate to severe disability (MS-D, two or more ADL domains required some/full help; n=140). We evaluated falls, frailty, health-related quality of life (HRQoL), mortality, and hospitalization. Results: The numbers of participants with a fall during the last 1 year were 199 (15.2%), 42 (25.8%), and 44 (31.4%) in the Non-D, Mild-D, and MS-D groups, respectively (p<0.001). The numbers of participants with frailty in the Non-D, Mild-D, and MS-D groups were 381 (29.0%), 84 (51.5%), and 93 (66.4%), respectively (p<0.001). In both univariate and multivariate analyses, the physical component scale and mental component scale scores decreased as the grade of disability increased (p<0.001 for both scores). Hospitalization-free survival rate at 500 days was 64.2%, 56.7%, and 51.1% in the Non-D, Mild-D, and MS-D, respectively (p=0.001 for trend). Patient survival rate at 500 days was 95.3%, 89.5%, and 92.3% in the Non-D, Mild-D, and MS-D, respectively (p=0.005 for trend). Conclusion: Disability was associated with falls, frailty, HRQoL scales, and survival trends in Korean dialysis patients.

• Structural Engineering and Mechanics
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• 제82권2호
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• pp.173-189
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• 2022

This study presents an experimental and numerically study about the effects of fiber reinforcement ratio on the behavior of concrete-filled steel tubes (CFST) under dynamic impact loading. In literature have examined the behavior of GFRP and FRP wrapped strengthened CFST elements impact loads. However, since the direction of potential impact force isn't too exact, there is always the probability of not being matched the impact force of the area where the reinforced. Therefore, instead of the fiber textile wrapping method which strengthens only a particular area of CFST element, we used fiber-added concrete-filled elements which allow strengthening the whole element. Thus, the effect of fiber-addition in concrete on the behavior of CFST elements under impact loads was examined. To do so, six simply supported CFST beams were constructed with none fiber, 2% fiber and 10% fiber reinforcement ratio on the concrete part of the CFST beam. CFST beams were examined under two different impact loads (75 kg and 225 kg). The impactors hit the beam from a 2000 mm free fall during the experimental study. Numerical models of the specimens were created using ABAQUS finite element software and validated with experimental data. The obtained results such as; mid-span displacement, acceleration, failure modes and energies from experimental and numerical studies were compared and discussed. Furthermore, the Von Misses stress distribution of the CFST beams with different ratio of fiber reinforcements were investigated numerically. To sum up, there is an optimum amount limit of the fiber reinforcement on CFST beams. Up to this limit, the fiber reinforcement increases the structural performances of the beam, beyond that limit the fiber reinforcement decreases the performances of the CFST beam under transverse impact loadings.

• 천문학회보
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• 제45권1호
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• pp.52.4-53
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• 2020

It is less well known that the properties, especially the mass accretion rate, of accretion flow are affected by the angular momentum of accreting gas. Park (2009) found that the mass accretion rate \dot{m}, mass accretion rate in units of Bondi accretion rate, is inversely proportional to the angular momentum of gas λ, at the Bondi radius where gas sound speed is equal to the free-fall velocity and proportional to the viscosity parameter α, and also Narayan & Fabian (2011) found a similar relation, but the dependence of the mass accretion rate of the gas angular momentum is much weaker. In this work, we investigate the global solutions for the rotating Bondi flow, i.e., polytropic flow accreting via viscosity, for various accretion parameters and the dependence of the mass accretion rate on the physical characteristics of gas. We set the outer boundary at various radius r_{out}=10^3~10^5 r_{Sch}, where r_{Sch} is the Schwarzschild radius of the black hole. For a small Bondi radius, the mass accretion rate changes steeply, as the angular momentum changes, and for a large Bondi radius, the mass accretion rate changes gradually. When the accreting gas has a near or super Keplerian rotation, we confirm that the relation between the mass accretion rate and angular momentum is roughly independent of Bondi radius as shown in Park (2009). We find that \dot{m} is determined by the gas angular momentum at the Bondi radius in units of r_{Sch}c. We also investigate the solution for the rotating Bondi flow with the outflow. The outflow affects the determination of the mass accretion rate at the outer boundary. We find that the relation between the mass accretion and the gas angular momentum becomes shallower as the outflow strengthens.

• 한국유기농업학회지
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• 제25권1호
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• pp.85-99
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• 2017

9년생 '신고'배(Pyrus pyrifolia Nakai)나무 과원에서 화학비료 대체 기술을 확립하고자 녹비작물의 예초시기와 예초높이에 따른 무기성분의 환원량을 2009년에 비교하였다. 호밀과 헤어리베치를 2008년 가을에 혼파하여 예초시기를 기준으로 총 4가지 처리를 포함하였다. 4월 18일에 1차 예초와 5월 28일에 2차 예초 한 것을 4월 18일+5월 28일 예초 처리구로 설정하였고, 4월 28일+6월 8일 예초, 5월 8일+6월 18일 예초, 4월 18일+5월 18일+6월 18일 예초처리를 시험에 이용하였다. 예초높이 처리는 $3{\pm}1cm$, $7{\pm}1cm$, $13{\pm}1cm$ 높이에서 4월 18일과 6월 8일에 각각 예초한 것을 포함하였다. 예초 시기별 처리에서, 5월 8일+6월 18일 예초처리가 녹비작물과 자연초종의 건물중 생산량이 ha당 14,480 kg으로 가장 높았고, 이에 따라 토양에 환원되는 전질소와 칼륨도 ha당 각각 292 kg과 396 kg으로 가장 높았다. 예초 높이 처리에서는 $7{\pm}1cm$ 처리에서 녹비작물과 자연초종의 건물중 생산량이 ha당 11,970 kg으로 가장 낮아서 전질소와 인산, 그리고 칼륨이 ha당 각각 265 kg, 111 kg, 333 kg으로 가장 낮았다. 녹비작물 처리는 예초방법에 상관없이 토양의 유기물 함량을 다소 증가시켰던 것으로 관찰되었다.

• 한국산학기술학회논문지
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• 제20권3호
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• pp.417-422
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• 2019

혈역학적으로 불안정한 골반골 골절 환자의 사망율은 40-60%에 이를 정도로 매우 높다. 하지만 이러한 환자들을 어떻게 치료해야 하는지에 대해서는 아직 논란의 여지가 많다. 저자들은 혈역학적으로 불안정한 골반골 골절 환자에서 빠른 응급 혈관조영술을 통해 효과적으로 지혈을 시행한 증례를 보고하고자 한다. 78세 여자가 넘어져서 발생한 골반 통증을 주소로 응급실을 통해 내원하였다. 내원 후 시행한 단순골반촬영에서 골반골 골절이 관찰되었으며, 혈압은 60/40 mmHg였다. 혈역학적으로 불안정하여 전산화단층촬영을 시행하지 않고 곧바로 혈관조영술을 시행하였으며, 빠른 지혈을 위해 세부적인 출혈 혈관을 선택하지 않고 양측 내장골동맥에 대해 색전술을 시행하였다. 색전술 시행 후 혈압이 안정화되고 나서 전산화단층촬영을 시행하였으며, 이 검사에서 장천공을 의심할 수 있는 다수의 복강내 공기 음영이 관찰되었다. 응급 개복술을 시행하였으며, 수술 소견상 소장에 약 1 cm 크기의 천공이 관찰되어 봉합을 시행하였고, 골반 주변 후복막강에 혈종이 있었으나 더 이상 팽창하지 않고 출혈 소견이 보이지 않아 그대로 두고 수술을 종료하였다. 환자는 중환자실로 입원하여 집중치료 시행하였고, 수술 3일째 일반병실로 전실하였다. 저자들은 이 증례에서 출혈을 동반한 골반골 골절과 소장천공 대해 전산화 단층촬영을 생략하고 빠른 혈관 조영술을 시행하여 효과적으로 치료할 수 있었다.

• 대한화장품학회지
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• 제47권1호
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• pp.31-40
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• 2021

프레스드 파우더의 주요 안정성 요인으로 경도와 낙하 안정도가 있다. 일반적으로 탈크가 포함된 프레스드 파우더의 경우 경도와 낙하 안정도를 고르게 충족시키며 사용감도 우수하지만 최근 탈크의 석면 이슈로 인해 대체를 원하는 고객들이 늘고 있다. 따라서 안정성을 유지하면서 사용감도 떨어지지 않는 탈크 프리 프레스드 파우더 제형의 개발이 시급하다. 본 연구에서는 탈크 프리 프레스드 파우더를 만들기 위한 최적의 원료 배합 비율을 찾기 위한 실험을 진행하였다. 파우더에 주로 사용되는 원료들의 특성을 확인하고 비율을 변화시켜 실험하여 명도와 경도를 측정하고 낙하 시험을 실시하였다. 천연 마이카 함량이 합성 마이카보다 많거나, 코팅된 실리카 대신 논 코팅 실리카를 사용할 경우 탈크가 포함된 내용물보다 경도와 낙하 안정도는 낮지만 명도는 유사하였다. 반대로 합성 마이카 함량이 천연 마이카 함량과 동일하거나 높을 경우, 코팅된 실리카 함량이 논코팅 실리카 함량과 동일하거나 높은 경우에 탈크가 포함된 내용물의 경도, 낙하 안정도와는 유사하였으나 명도는 낮게 측정되었다. 탈크가 포함된 내용물보다 경도는 높지만 낙하 안정성은 떨어지는 현상도 발견하여 경도와 낙하 안정성의 상관관계에 대해서는 추가적인 연구가 필요할 것으로 생각된다.

• 한국수자원학회논문집
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• 제56권spc1호
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• pp.1049-1058
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• 2023

보와 저낙차 댐과 같은 하천횡단구조물을 통과하는 흐름은 도수 현상을 동반하는 급변류가 지배적이다. 구조물 하류에서 도수로 인한 유속과 수면의 강한 비정상성은 수공구조물의 안정에 영향을 줄 수 있다. 특히, 높은 Froude 수 조건에서 발생하는 정상도수는 공기연행이 현저하게 발생하여 흐름 특성은 더욱 복잡해진다. 이 연구에서는 Froude 7.3 조건에서 발생하는 정상도수를 모의하기 위해서 큰와모의 기법과 하이브리드 VoF 기법을 이용한 수치모의를 수행하였다. 수치모의 결과는 구조물 하류 바닥면에서 계측된 순간최대압력과 시간평균압력 분포를 유사하게 재현하는 것으로 나타났다. 단, 구조물 직하류에서의 순간최소압력 분포는 대상으로 하는 실험 계측값과 반대의 양상을 보이지만, 유사한 다른 시험과는 같은 양상을 보임으로써 본 연구에서 수행한 수치모의는 합리적으로 압력변동을 예측하는 것으로 판단된다. 도수 중앙부에서의 연직방향 유속분포와 공기농도분포는 유사한 조건의 실험 결과들과 자기상사성을 보이면서 양호하게 일치하는 것으로 나타났다. 이러한 결과는 본 연구에서 적용한 큰와모의 기법과 하이브리드 VoF 기법이 높은 Froude 수 조건에서 강한 공기연행을 동반하는 도수현상을 양호하게 재현할 수 있음을 보여준다.

• Journal of Nutrition and Health
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• 제1권2호
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• pp.107-115
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• 1968

Number of aspects, not only nutritional but social as well as political involved in human starvation pose nowadays global problems. In order to help establish the minimum nutritional requirements in the daily life of a man and to free people as well from either undernourishment, malnutrition or even starvation many workers have devoted themselves so far on the research programs to know what and how number of metabolic events take place in animals in vivo. It is the purpose of the present paper to examine in effect to what extent both of the protein and nucleic acids (DNA & RNA) together with an enzyme, guanine deaminase, which converts guanine into xanthine and in turn ends up to uric acid as an end product, undergo changes, quantitatively during acute starvation, using the mouse as an experimental animal. The mouse was strictly inhibited from taking foods except drinking water ad libitum and was sacriflced 24, 48, and 72 hours following starvation thus acutely induced. The animals consisted of two experimental groups, one control and another starvation groups, each being consisted of 6-24 mice of whose body weights ranged in the vicinity of 10 g. The animals were sacriflced by a blow on the head, followed by immediate excision of their livers into ice-cold distilled water, washing adherent blood and other contaminant tissues. The liver was minced foramin, by an all-glass homogenizer immersing it in an ice-bath, followed by subsequent fractionatin of the homogenate (10% W/V in 0.25M sucrose solution made up with 0.05M phosphate buffer of pH 7.4). For the liver protein and guanine deaminase assay, the 10% homogenate was centrifuged at 600 x g for 10 minutes to eliminate the nuclear fraction; and for the estimation of DNA and RNA, the homogenate was prepared by the addition of 10% trichloroacetic acid in order to free the homogenate from the acid-soluble fraction, the remaining residue being delipidate by the addition of alcohol and dried in vacuo for later KOH (IN) hydrolysis. The changes in body and liver wegihts during acute starvation were checked gravimetrically. Protein contents in the liver were monitored by the method of Lowry et al; and guanine deaminase activities were followed by the assay of liberated ammonia from the substrate utilizing the Caraway's colorimetry. The extraction of both DNA and RNA was performed by the Schmidt-Thannhauser's method, which was followed by Marmur's method of purification for DNA and by Chargaff's method of purification for RNA. The determinations of both DNA and RNA were carried out by the diphenylamine reaction for the former and by the orcinol reaction for the latter. The following resume was the results of the present work. 1. It was observed that the body as well as liver weights fall abruptly during starvation, and that the loss of body weight showed no statistical correlation with the decreases in the content of liver protein. 2. The content of liver protein and activity of liver guanine deaminase activity as well decline dramatically, and the specific activities of the enzyme (activity/protein), however, decreased gradually as starvation proceeded. 3. Both of the nucleic acids, DNA and RNA, showed decrements in the liver of mouse during acute starvation; the latter, however, being more striking in the decline as compared to the former. 4. The decreases in the liver protein content as resulted from the acute starvation had no statistically significant correlation with the decrements of DNA in the same tissue, but had regressed with a significant statistical correlation with the fall of RNA in the tissue. 5. The decrease in the activity of guanine deaminase in the liver of mouse during acute starvation was functionally more proportional to the decrease in RNA than DNA, and moreover correlated with the changes in the content of the liver protein. 6. The possible mechanisms involved during in this acute starvation as bring the decreases in the contents of DNA, protein, and guanine deaminase were discussed briefly.

• 한국가축번식학회지
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• 제17권4호
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• pp.311-323
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• 1994

This study was conducted to observe seasonal and individual changes in semen characteristics and sperm freezability, and sperm penetration into zona-free hamster eggs in Korean native goats. Buck response and change in semen characteristics to electrical stimulations was evaluated for four seasons throughout 2 years and percentage of motile sperm and normal apical ridge acrosome was investigated after equilibration and thawing for 4 seasons with 5 bucks. Sperm penetration rate was evaluated for 4 bucks. 1. Probe insertion at depth of 7cm and repeated stimulation for 3 sec was more effective(P<0.05) in buck response and semen collection than those of other conditions. 2. Semen characteristics from electrojaculation was signficantly(P<0.005) higher in spring and fall for semen volume, in spring and summer for sperm concentration and in fall for sperm motility than those in other seasons, respectively. However, there were no differences in total sperm among seasons. 3. Buck response to electrical stimulation showed significant difference(P<0.05) among individuals in all 3 seasons except winter. Significant individual difference in semen volume was only in spring and summer, but there was no indivudual difference in sperm concentration and total sperm in all season. 4. Washing of semen before freezing treatment was greatly(P<0.05) beneficial to sperm motility after thawing, no matter whether ejaculates exhibit egg yolk coagulation or not. 5. Sperm motility after glycerol equilibration was significantly(P<0.05) low in summer semen and motility after thawing was greatly(P<0.05) higher in winter semen than in other seasons. Freezability of unwashed sperm was significantly difference among bucks, but a yearly freezability of washed sperm after chilling and thawing were no differences among bucks and percentage of normal apical ridge acrosome were not different among seasons and bucks. 6. There was no significant difference in sperm motility after thawing between egg yolk levels in summer, although 20% level gave more higher motility than 5% level. 7. In summer, 3.2% glycerol and 3-h equilibration gave greatest percentage(P<0.05) of sperm motility and normal apical ridge acrosome after thawing. 8. Sperm penetration rate into zona-free hamster eggs was not different between bucks and seasons. Overall, it is concluded that to obtain maximum sperm output and successive semen freezing by electrojaculation method, buck selection with good response in all season could be basically considered and that seasonal effect on sperm freezability was more greater than that of individual bucks.

• 생명과학회지
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• 제26권5호
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• pp.519-530
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• 2016

자연상태에서 녹색인 채로 눈에 덮여 있는 냉동사료 엽채식물은 초식동물의 생물활성물질과 영양분의 근원이 된다. 우리는 Avena sativa, Elytrigia repens, Equisetum variegatum과 Equisetum scirpoides의 잎에서 가을에 전체 지방산 함량이 상당히 증가함을 관찰하였다. 그러나, 여름에 채취한 잎에 비하여 눈에 덮혀 얼어있는 식물에서 지방산 불포화도의 증가는 없었다(북반부 온도최저점 지역에 서식하는 키가 작은 쇠뜨기인 E. scirpoides는 예외임). 야쿠티아 말의 내부 지방조직(젊은 말의 고기)에서, 18개의 지방산이 분석되었고, 그 중 10개가 포화 지방산이었다. 그 중 70%에 해당하는 양으로 단일불포화 올레산(С18:1(n-9))과 고도불포화 α-리놀렌산이 비슷하게 분포하였다. 내부 지방조직에 이렇게 많은 고도불포화 지방산이 많이 분포하는 것은 가을과 겨울에 먹인 녹색 먹이의 영향으로 본다. 우리는 야쿠티아 말의 조직에 상당한 양으로 분포하는 식물 특이적 지방산 함량은 이 말들이 오래 동안 저온 스트레스 상황에서 저항성을 가질 수 있은 조절기작에 중요한 역할을 한다고 제안한다.