• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.2
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• pp.28-32
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• 2014

Purpose Patient motion during myocardial perfusion SPECT can produce images that show visual artifacts and perfusion defects. This artifacts and defects remain a significant source of unsatisfactory myocardial perfusion SPECT. Motion correction has been developed as a way to correct and detect the patient motion for reducing artifacts and defects, and each motion correction uses different algorithm. We corrected simulated motion patterns with several motion correction methods and compared those images. Materials and Methods Phantom study was performed. The anthropomorphic torso phantom was made with equal counts from patient's body and simulated defect was added in myocardium phantom for to observe the change in defect. Vertical motion was intentionally generated by moving phantom downward in a returning pattern and in a non-returning pattern throughout the acquisition. In addition, Lateral motion was generated by moving phantom upward in a returning pattern and in a non-returning pattern. The simulated motion patterns were detected and corrected similarly to no-motion pattern image and QPS score, after Motion Detection and Correction Method (MDC), stasis, Hopkins method were applied. Results In phantom study, Changes of perfusion defect were shown in the anterior wall by the simulated phantom motions, and inferior wall's defect was found in some situations. The changes derived from motion were corrected by motion correction methods, but Hopkins and Stasis method showed visual artifact, and this visual artifact did not affect to perfusion score. Conclusion It was confirmed that motion correction method is possible to reduce the motion artifact and artifactual perfusion defect, through the apply on the phantom tests. Motion Detection and Correction Method (MDC) performed better than other method with polar map image and perfusion score result.

• The Journal of the Acoustical Society of Korea
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• v.24 no.1
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• pp.43-51
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• 2005

In this paper, we propose an algorithm that improves a tone quality of a noisy audio signal in order to enhance a Performance of perceptual filter using noise energy control. Most of the algorithms which were proposed by the other researchers usually applied a filter using the noise energy acquired from a silent range. In this case. the improvement rate of tone quality decreases if the noise energy is changed by the magnitude or environment variation in a signal frame. But the Proposed method Provides the means to find a food estimated noise through energy control of the estimated noise which is obtained from a silent range. Also we can get the enhancement of tone qualify in low frequency band unlike other methods. To show the performance of the Proposed algorithm, various input signals which had a different signal-to-noise ratio (SNR) such as 5dB, l0dB, 15dB and 20dB were used to test the proposed algorithm. With the proposed algorithm, we could confirm the enhancement of tone quality in terms of segmental SNR (SSNR). noise-to-mask ration (NMR) and mean opinion score (MOS) test.

• Journal of Korean Academy of Nursing
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• v.46 no.1
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• pp.149-158
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• 2016

Purpose: This study was done to develop of the Korean intensive care delirium screening tool (KICDST). Methods: The KICDST was developed in 5 steps: Configuration of conceptual frame, development of preliminary tool, pilot study, reliability and validity test, development of final KICDST. Reliability tests were done using degree of agreement between evaluators and internal consistency. For validity tests, CVI (Content Validity Index), ROC (Receiver Operating Characteristics) analysis, known group technique and factor analysis were used. Results: In the reliability test, the degree of agreement between evaluators showed .80~1.00 and the internal consistency was KR-20=.84. The CVI was .83~1.00. In ROC analysis, the AUC (Area Under the ROC Curve) was .98. Assessment score was 4 points. The values for sensitivity, specificity, correct classification rate, positive predictive value, and negative predictive value were found to be 95.0%, 93.7%, 94.4%, 95.0% and 93.7%, respectively. In the known group technique, the average delirium screening tool score of the non-delirium group was $1.25{\pm}0.99$ while that of delirium group was $5.07{\pm}1.89$ (t= - 16.33, p <.001). The factors were classified into 3 factors (cognitive change, symptom fluctuation, psychomotor retardation), which explained 67.4% of total variance. Conclusion: Findings show that the KICDST has high sensitivity and specificity. Therefore, this screening tool is recommended for early identification of delirium in intensive care patients.

• Journal of radiological science and technology
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• v.42 no.1
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• pp.53-59
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• 2019

In the field of nuclear medicine, the various static phantoms of international standards are used to assess the performance of the nuclear medicine equipment. However, we only reproduced a fixed situation in spite of the movement of the cardiac, and the demands for dynamic situations have been continuously raised. More research is necessary to address these challenges. This study used flexible materials to design the dynamic cardiac phantom, taking into account the various clinical situations. It also intended to reproduce the images through dynamic cardiac flow to confirm the usefulness of the proposed technique. The frame of dynamic cardiac phantom was produced based on the international standard phantom. A nuclear medicine dynamic cardiac phantom was produced rubber material and silicone implemented by 3D printing technique to reproduce endocardium and epicardium movement. Therefore we compared and evaluated the image of a cardiac phantom made of rubber material and a cardiac phantom made of silicone material by 3D printing technique. According to the results of this study, the analysis of the Summed Rest Score(SRS) showed abnormalities in the image of a cardiac phantom made of rubber material at 10, 20, and 30 stroke rates, but the image of a cardiac phantom made of silicone material by 3D printing technique showed normal levels. And the analysis of the Total Perfusion Deficit(TPD) showed that TPD in the image of a cardiac phantom made of rubber material was higher than that of the image of a cardiac phantom made of silicone material by 3D printing technique at 10, 20, and 30 stroke rates. The potential for clinical application of the proposed method was confirmed in the dynamic cardiac phantom implemented with 3D printing technique. It is believed that the objective information secures the reliability of inspection equipment and it contributes to improve the diagnostic value of nuclear medicine.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.122-127
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• 2010

Purpose: The Xpress3.$cardiac^{TM}$ which is a kind of wide beam reconstruction (WBR) method developed by UltraSPECT (Haifa, Israel) enables the acquisition of at quarter time while maintaining image quality. The purpose of this study is to investigate the usefulness of WBR method for decreasing scan times and to compare to it with filtered back projection (FBP), which is the method routinely used. Materials and Methods: Phantom and clinical studies were performed. The anthropomorphic torso phantom was made on an equality with counts from patient's body. The Tl-201 concentrations in the compartments were 74 kBq (2 ${\mu}Ci$)/cc in myocardium, 11.1 kBq (0.3 ${\mu}Ci$)/cc in soft tissue, and 2.59 kBq (0.07 ${\mu}Ci$)/cc in lung. The non-gated Tl-201 myocardial perfusion SPECT data were acquired with the phantom. The former study was scanned for 50 seconds per frame with FBP method, and the latter study was acquired for 13 seconds per frame with WBR method. Using the Xeleris ver. 2.0551, full width at half maximum (FWHM) and average image contrast were compared. In clinical studies, we analyzed the 30 patients who were examined by Tl-201 gated myocardial perfusion SPECT in department of nuclear medicine at Asan Medical Center from January to April 2010. The patients were imaged at full time (50 second per frame) with FBP algorithm and again quarter-time (13 second per frame) with the WBR algorithm. Using the 4D MSPECT (4DM), Quantitative Perfusion SPECT (QPS), and Quantitative Gated SPECT (QGS) software, the summed stress score (SSS), summed rest score (SRS), summed difference score, end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were analyzed for their correlations and statistical comparison by paired t-test. Results: As a result of the phantom study, the WBR method improved FWHM more than about 30% compared with FBP method (WBR data 5.47 mm, FBP data 7.07 mm). And the WBR method's average image contrast was also higher than FBP method's. However, in result of quantitative indices, SSS, SDS, SRS, EDV, ESV, EF, there were statistically significant differences from WBR and FBP(p<0.01). In the correlation of SSS, SDS, SRS, there were significant differences for WBR and FBP (0.18, 0.34, 0.08). But EDV, ESV, EF showed good correlation with WBR and FBP (0.88, 0.89, 0.71). Conclusion: From phantom study results, we confirmed that the WBR method reduces an acquisition time while improving an image quality compared with FBP method. However, we should consider significant differences in quantitative indices. And it needs to take an evaluation test to apply clinical study to find a cause of differences out between phantom and clinical results.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.11C
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• pp.655-661
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• 2011

The transmission issues for the scalable video coding extension of H.264/AVC (H.264 SVC) video has been widely studied. In this paper, we propose an objective video-quality assessment metric based on no-reference for H.264 SVC using scalability information. The proposed metric estimate the perceptual video-quality reflecting error conditions with the consideration of the motion vectors, error propagation patterns with the hierarchical prediction structure, quantization parameters, and number of frame which damaged by packet loss. The proposed metric reflects the human perceptual quality of video and we evaluate the performance of proposed metric by using correlation relationship between differential mean opinion score (DMOS) as a subjective quality and proposed one.

• IEIE Transactions on Smart Processing and Computing
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• v.2 no.5
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• pp.255-265
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• 2013

3DTV is expected to be a promising next-generation broadcasting service. On the other hand, the visual discomfort/fatigue problems caused by viewing 3D videos have become an important issue. This paper proposes a perceptual quality assessment metric for a stereoscopic video (SV-PQAM). To model the SV-PQAM, this paper presents the following features: temporal variance, disparity variation in intra-frames, disparity variation in inter-frames and disparity distribution of frame boundary areas, which affect the human perception of depth and visual discomfort for stereoscopic views. The four features were combined into the SV-PQAM, which then becomes a no-reference stereoscopic video quality perception model, as an objective quality assessment metric. The proposed SV-PQAM does not require a depth map but instead uses the disparity information by a simple estimation. The model parameters were estimated based on linear regression from the mean score opinion values obtained from the subjective perception quality assessments. The experimental results showed that the proposed SV-PQAM exhibits high consistency with subjective perception quality assessment results in terms of the Pearson correlation coefficient value of 0.808, and the prediction performance exhibited good consistency with a zero outlier ratio value.

• Journal of Korean Neurosurgical Society
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• v.56 no.3
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• pp.206-210
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• 2014

Objective : Lumbar spinal stenosis is a common degenerative spine disease that requires surgical intervention. Currently, there is interest in minimally invasive surgery and various technical modifications of decompressive lumbar laminectomy without fusion. The purpose of this study was to present the author's surgical technique and results for decompression of spinal stenosis. Methods : The author performed surgery in 57 patients with lumbar spinal stenosis between 2006 and 2010. Data were gathered retrospectively via outpatient interviews and telephone questionnaires. The operation used in this study was named central decompressive laminoplasty (CDL), which allows thorough decompression of the lumbar spinal canal and proximal two foraminal nerve roots by undercutting the lamina and facet joint. Kyphotic prone positioning on elevated curvature of the frame or occasional use of an interlaminar spreader enables sufficient interlaminar working space. Pain was measured with a visual analogue scale (VAS). Surgical outcome was analyzed with the Oswestry Disability Index (ODI). Data were analyzed preoperatively and six months postoperatively. Results : The interlaminar window provided by this technique allowed for unhindered access to the central canal, lateral recess, and upper/lower foraminal zone, with near-total sparing of the facet joint. The VAS scores and ODI were significantly improved at six-month follow-up compared to preoperative levels (p<0.001, respectively). Excellent pain relief (>75% of initial VAS score) of back/buttock and leg was observed in 75.0% and 76.2% of patients, respectively. Conclusion : CDL is easily applied, allows good field visualization and decompression, maintains stability by sparing ligament and bony structures, and shows excellent early surgical results.

• Microbiology and Biotechnology Letters
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• v.47 no.2
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• pp.278-288
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• 2019

In the present investigation, we attempted to design a protocol to develop a hybrid protein with better bioremediation capacity. Using in silico approaches, a Hybrid Open Reading Frame (Hybrid ORF) is developed targeting the genes of microorganisms known for degradation of organophosphates. Out of 21 genes identified through BLAST search, 8 structurally similar genes (opdA, opd, opaA, pte RO, pdeA, parC, mpd and phnE) involved in biodegradation were screened. Gene conservational analysis categorizes these organophosphates degrading 8 genes into 4 super families i.e., Metallo-dependent hydrolases, Lactamase B, MPP and TM_PBP2 superfamily. Hybrid protein structure was modeled using multi-template homology modeling (3S07_A; 99%, 1P9E_A; 98%, 2ZO9_B; 33%, 2DXL_A; 33%) by $Schr{\ddot{o}}dinger$ software suit version 10.4.018. Structural verification of protein models was done using Ramachandran plot, it was showing 96.0% residue in the favored region, which was verified using RAMPAGE. The phosphotriesterase protein was showing the highest structural similarity with hybrid protein having raw score 984. The 5 binding sites of hybrid protein were identified through binding site prediction. The docking study shows that hybrid protein potentially interacts with 10 different organophosphates. The study results indicate that the hybrid protein designed has the capability of degrading a wide range of organophosphate compounds.

• The Journal of the Korea Contents Association
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• v.11 no.8
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• pp.211-220
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• 2011

The study conducted a survey on the perception level for radiological technologists with 321 nurses and auxiliary nurses working at university hospitals in Busan in order to supply preliminary data to enhance the status as well as professional images of radiological technologists. The result shows the perception level of $3.02{\pm}0.42$ with the highest score for the professional image and the lowest score for the business image. By question, 'they are professional' gets the highest score while 'they understand problems of patients well' gets the lowest. Among respondents, those who are well aware of education courses as well as leading organization of examination and who answer as a health care provider or a medical technician under the medical law show a high level of perception while those who answer as technician show a low perception level. Those who agree with radiologists as a career and consider their status as high in medical institutions have a high level of perception. In order to improve the perception level, individuals as well as associations' promotion and strategies are required to fix the title and enhance the negative images through active interests and kind attitudes toward patients. Also, efforts to escape from previous images limited to technical colleges, to vitalize academic conference and remedial education, and to frame the law of professional radiological technologists system are asked to heighten the qualification and status of radiological technologists. More than that, advertising and monitoring via mass media are needed to develop the image as professional career men as well.