• BMB Reports
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• v.28 no.5
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• pp.464-470
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• 1995

Quinolone antibiotics are DNA gyrase inhibitors, but their bactericidal action seems to involve more than the inhibition of DNA gyrase activity. Hence, the potentially crucial factors among possible mechanisms of quinolone action; cleavable complex formation, inhibition of DNA synthesis, and induction of SOS response were investigated. These parameters were measured in an Escherichia coli strain exposed to quinolones in the logarithmic growth phase, and correlated with the bactericidal activity of quinolones. Cleavable complex formation proved to be the factor most related to bactericidal action. Inhibition of DNA synthesis was substantially correlated with bactericidal activity, but induction of SOS response was least correlated with bactericidal activity. Therefore, it was concluded that quinolones exert bactericidal action primarily through cleavable complex formation, and subsequent unknown cellular processes together with inhibition of DNA synthesis contribute to the bactericidal activity of quinolones.

• Journal of Korea Foundry Society
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• v.18 no.3
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• pp.275-282
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• 1998

The squeeze casting of a Mg-5wt%Al-0.6wt%Zr alloy was carried out to investigate the conditions for the formation and the prevention of macrodefects, such as macrosegregation and shrinkage defects. The effects of the process parameters, the applied pressure, the die temperature, and the pouring temperature on the formation of macrodefcts were investigated in correlation with the evolution of macrostructure. Three types of macrodefects were found; macrosegregation only, shrinkage defects only, both macrosegregation and shrinkage defects. It was found that the pouring temperature, the die temperature, and the applied pressure are closely related to the formation of macrodefects. Sound castings without macrosegregation and shrinkage defects can be obtained under the conditions of 80 MPa$730^{\circ}C$$760^{\circ}C$, and $180^{\circ}C$<$T_D$<$250^{\circ}C$.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.245-248
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• 2002

Vortex lock-on or resonance in the flow behind a circular cylinder is visualized by a time-resolved PIV when a single frequency oscillation is superimposed on the mean incident velocity. Measurements are made of the $K{\'{a}}rm{\'{a}}n$ vortices in the wake-transition regime at the Reynolds number 360. Basically, natural shedding state is observed to compare with lock-on state. Wake motion by the change of the shedding frequency of lock-on state is investigated. When lock-on occurs, the vortex shedding frequency is found to be half the oscillation frequency as expected from previous experiments. The physical flow phenomena of natural shedding and lock-on states are analyzed with physical parameters of recirculation and vortex formation region. Consequently, it is found that the change of wake bubble plays an important role in the flow at the lock-on state. Vortex formation region is also actively changed like recirculation region as the lock-on occurs. Therefore, it is deduced that the recirculation region is closely related with the vortex formation region.

• Journal of Welding and Joining
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• v.21 no.3
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• pp.58-67
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• 2003

In this study, the formation mechanism of discontinuities in the laser fusion zone of diamond saw blade was investigated. $CO_2$ laser weldings were conducted along the butt between Fe base sintered tip and carbon steel shank with sets of variable welding parameters. The effect of heat input on irregular humps, outer cavity, inner cavity and bond strengh was evaluated. The optimum heat input to have a proper humps was in the range of 10.4~$17.6kJm_{-1}$. With increasing heat input, both outer and inner cavities were reduced. The outer cavity was caused by insufficient refill of keyhole, while inner cavity was caused by trapping of bubble in molten metal. The bubble came from sintered tip and intensive vaporization at bottom tip of the keyhole. A gas formation and low melting point element vaporization were not occurred during welding. We could not find any relationship between bond strength and amount of discontinuities. Because the fracture were occurred in not only sintered tip but also carbon steel shank due to hardness distributions.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.2
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• pp.199-205
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• 2001

Burr makes troubles on manufacturing process due to deburring cost, quality of products and productivity. This paper described the results of experimental study on the influence of the cutting parameters on the formation of exit burrs in face milling. Using the results of experimental study, burr types are classified and data bases are developed to predict burr formation result. From the CAD file for work geometry and the NC data for tool path, the exit angles are calculated at every edges. This program predicts the burr geometry at exit edges using the prediction algorithm and data bases which are developed experimentally. Simulation results on deformation strain and temperature are also available in specific 2-dimensional cutting conditions. Also algorithm which can determine the exit angle is proposed.

• Journal of The Korean Astronomical Society
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• v.37 no.3
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• pp.91-117
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• 2004

We analyze the dependence of the mass-to-light ratio of spiral galaxies on the present star formation rate (SFR), and find that galaxies with high present star formation rates have low mass-to-light ratios, presumably as a result of the enhanced luminosity. On this basis we argue that variations in the stellar content of galaxies result in a major source of intrinsic scatter in the Tully-Fisher relation (TF relation). Ideally one should use a 'population-corrected' luminosity. We have also analyzed the relation between the (maximum) luminous mass and rotational velocity, and find it to have a small scatter. We therefore propose that the physical basis of the Tully-Fisher relation lies in a relationship between the luminous mass and rotational velocity, in combination with a 'well-behaved' relation between luminous and dark matter. This implies that the Tully-Fisher relation is a combination of two independent relations: (i) a relation between luminosity and (luminous) mass, based mainly on the star formation history in galaxies, and (ii) a relation between mass and rotation velocity, which is the outcome of the process of galaxy formation. In addition to a 'population-corrected' Tully-Fisher relation, one may also use the relation between mass and luminosity, and the relation between luminous mass and rotation velocity as distance estimators.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1994.05a
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• pp.152-153
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• 1994

A recessed $n^{+}$-p junction diode with the serf-aligned structure is proposed and fabricated by using the polysilicon as an $n^{+}$ diffusion source. The diode structure can be applicable to the emitter-base formation of high performance bipolar device and the $n^{+}$ polysilicon emitter has an important effect on the device characteristics. The considered parameters for the polysilicon formation are the deposition condition $As^{+}$ dose for the doping of the polysilicon, and the annealing using RTP system. The vertical depth profiles of the fabricated diode are obtained by SIMS. The eleotrical characteristics are analyzed in trims of the ideality factor of diode (n), contact resistance arid reverse leakage current. The $As_{+}$ dose for the formation of good junction is current. The $As^{+}$ dose for the formation of goodjunctions is about 1∼2${\times}$$10^{16}$$cm^{-2}$ at given RTA condition ($1100^{\circ}C$, 10 sec). The $n^{+}$-p structure is successfully applied to the self-aligned bipolar device adopting a single polysilicon technology.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2007.04a
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• pp.147-148
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• 2007

In this study, the technology to grow oriented nanotube thin film from dip-coated $TiO_2$ using hydrothermal method has been successfully developed. The effects of preparation parameters, such as reaction temperature, duration and post treatment conditions on the film morphologies and the adherence to the substrate, have been examined. A general formation mechanism of oriented titanate nanotube thin film is proposed in terms of the detailed observation of the products via two dimensional surface FESEM studies and HRTEM images. The overall formation of $TiO_2-based$ nanotube thin film can be summarized with three successive steps: (1) $TiO_2$ dissolving and amorphous $Na_2TiO_3$ deposition process; (2) layered $Na_2Ti_3O_7$ formation via spontaneous crystallization and rapid growth process; (3) formation of nanotube thin film via $Na_2Ti_3O_7$ splitting and multilayer scrolling process of (100) planes around the c axis of $Na_2Ti_3O_7$.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.20 no.4
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• pp.455-468
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• 2022

Colloid Formation and Migration (CFM) project is being carried out within the Grimsel Test Site (GTS) Phase Ⅵ. Since 2008, the Korea Atomic Energy Research Institute (KAERI) has joined CFM to investigate the behavior of colloid-facilitated radionuclide transport in a generic Underground Research Laboratory (URL). The CFM project includes a long-term in-situ test (LIT) and an in-rock bentonite erosion test (i-BET) to assess the in-situ colloid-facilitated radionuclide transport through the bentonite erosion in the natural flow field. In the LIT experiment, radionuclide-containing compacted bentonite was equipped with a triple-packer system and then positioned at the borehole in the shear zone. It was observed that colloid transport was limited owing to the low swelling pressure and low hydraulic conductivity. Therefore, a postmortem analysis is being conducted to estimate the partial migration and diffusion of radionuclides. The i-BET experiment, that focuses more on bentonite erosion, was newly designed to assess colloid formation in another flow field. The i-BET experiment started with the placement of compacted bentonite rings in the double-packer system, and the hydraulic parameters and bentonite erosion have been monitored since December 2018.

• Economic and Environmental Geology
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• v.56 no.4
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• pp.397-408
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• 2023

A total of 64 specimens of trace fossils were collected from the Jinju Formation of the construction site of Jinju Aviation Industrial Complex, and from the Haman Formation of Namhae Gain-ri fossil site. The fossils are continuously and regularly meandering sine-curve in shape. The fossil varies in morphology: width between 0.2 and 5.6 mm, wavelength between 1.5 and 28 mm, and amplitude between 0.9 and 7.9 mm; the Jinju specimens are commonly wider than the Haman ones. The ratio of wavelength to amplitude is more or less regular regardless of width of the specimen, and the linear correlation of the ratios shows that the Jinju specimens fit better than the Haman specimens. Taking all morphometric parameters, specimens in all size ranges are temporarily identified as ichnospecies Cochlichnus anguineus. In order to obtain more distinct and clearer images of Cochlichnus, we selected two specimens and applied a new imaging technology RTI. For photography of the trace fossils, 50 to 80 images were taken per set with photometric lighting close to the surface and horizontally. RTI technology clearly showed that the images of tiny fossils were improved: the surface contrast become sharper and messy and unnecessary information disappeared. Currently, RTI technology is used in many fields including preservation of cultural properties and archaeology. As a consequence, we hope to apply this technique to the field of paleontology, especially to the study of trace fossils of very small size.