• Title/Summary/Keyword: Form of Establishment

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Effects of Transcription Factor AP2γ on Gene Expression of Desmosome Components in Mouse Embryos

  • Chung, Hak-Jae;Jeong, Jiyeon;Jeong, Yelin;Choi, Inchul
    • Reproductive and Developmental Biology
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    • v.40 no.2
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    • pp.23-26
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    • 2016
  • Transcription factor called activating enhancer binding protein 2C (AP2-gamma) is found in a variety of species and expressed from oocyte stage onwards, particularly restricted to the trophectoderm. Recent studies demonstrated that ablation of Tfap2c led to failure of tight junction biogenesis, particularly the knock-down embryos of Tfap2c did not form cavity from morula to blastocyst in mouse and pig. We speculated that the Tfa2pc may also be involved in desmosome biogenesis because blastocoel formation is coincident with the establishment of desmosome. To determine this, we depleted Tfap2c injecting siRNA into one-cell zygote and analysed the expression levels of genes that are required for desmosome complex such as PkP2, Pkp3, Dsc2, and Dsg2. We found only Pkp3 was up-regulated in the knockdowned morula embryos. Interestingly, upstream region of Pkp3 had putative Tfap2c binding sites. In conclusion, our results suggest that Tfap2c is not a crucial factor but somehow it might be involved in desmosome biogenesis directly or indirectly via Pkp3.

A Study on the Changing Process of Ddeulzip in Jinsung Lee's Family at Andong Cultural Area (안동문화권 진성(眞城) 이씨(李氏) 뜰집의 변천과정(變遷過程))

  • Kim, Hwa-Bong
    • Journal of architectural history
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    • v.22 no.1
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    • pp.15-27
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    • 2013
  • The purpose of this study is to analyze the changing process in the Ddeulzip of Jinsung Lee clan family. The subject of this study is clan family of Jinsung Lee in Andong Cultural Area. The period of Chosun Dynasty is divided into largely three parts. The establishment process for Jinsung Lee's family is analyzed during early (15~16C) and mid(17~18C) periods, and changing process is analyzed during mid(19~20C) and late periods. The characteristics of early Chosun Ddeulzip is that it made a foundation to construct a Ddeulzip form. Those of mid Chosun period is in their strong will to preserve their ancestral house which is well manifested through the restoration of Taegye's ancestral house. During the late Chosun period, many of the different styles of Ddeulzip were constructed due to the stable environment of both political and economical status. The residential house of Jinsung Lee family that were centered in Yean area include diverse forms for both high and middle class social status. Jinsung Lee family's Ddeulzip is thus considered to bring about the firm foundation as a clan family representing the Andong cultural area through the development of Ddeulzip.

Biochemistry of Salicylic Acid and its Role in Disease Resistance

  • Lee, Hyung-Il;Raskin, Ilya
    • Korean Journal of Plant Tissue Culture
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    • v.24 no.4
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    • pp.233-238
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    • 1997
  • Salicylic acid (SA) is involved in the establishment of systemic acquired resistance (SAR) in many plant including tobacco. Considering the important role of SA in disease resistance, biosynthetic and metabolic pathways of SA in tobacco have been studied extensively: The initial step for biosynthetic pathway of SA is conversion of phenylalanine to trans-cinnamic acid, followed by decarboxylation of trans-cinnamic acid to benzoic acid and ie subsequent ring hydroxylation at the C-2 position to form SA. In TMV inoculated tobacco, most of the newly synthesized SA is glucosylated or methylated. Methyl salicylate has been identified as a biologically active, volatile signal. In contrast, the two glucosylated forms accumulate in the vicinity of lesions and consist of SA glucoside, a major metabolite, and SA glucose ester, a relatively minor from. Two enzymes involved in SA biosynthesis and metabolism have been purified and characterized : benzoic acid 2-hydroxylase which catalyzes conversion of benzoic acid to SA; UDP-Glucose: SA 1-O-D glucosyltransferase which converts SA to SA glucose ester. Further studies of the biosynthetic and metabolic pathways of SA will help to elucidate the SAR signal transduction pathway and provide potential tools for the manipulation of disease resistance.

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A Study on the Changing Process of Ddeulzip in Jaeryoung Lee's Family at Andong Cultural Area (안동문화권(安東文化圈) 재령이씨(載寧李氏) 뜰집의 변천과정(變遷過程))

  • Kim, Hwabong
    • Journal of architectural history
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    • v.24 no.2
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    • pp.45-54
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    • 2015
  • The purpose of this study is to analyze the changing process in the Ddeulzip of Jaeryoung Lee's clan family. The subject of this study is clan family of Jaeryoung Lee in Andong Area. The period of Ddeulzip's changing process is divided into largely three parts. The establishment process and changing process for Jaeryoung Lee's family is analyzed during early (15~16C), mid(17~18C) and late(19~20C) periods. The characteristics of early periods is that it made a main ancestral building of Ddeulzip form. Those of mid Chosun period is in their strong will to preserve their ancestral house. During the late period, many of the different styles of Ddeulzip were constructed due to the stable environment of both political and economical status. The residential house of Jaeryoung Lee family that were centered in Youngduk and Youngyang area include diverse forms for both high and middle class social status. Jaeryoung Lee family's Ddeulzip is thus considered to bring about the firm foundation as a clan family representing the Andong cultural area through the development of Ddeulzip.

A Study on The Modulor System Shown in Structure and Envelope of Le Corbusier's Works (Le Corbusier 건축의 구조와 외피에 나타나는 모듈러 시스템에 관한 연구)

  • Cho, Sung-Hyun
    • Journal of The Korean Digital Architecture Interior Association
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    • v.10 no.1
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    • pp.15-22
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    • 2010
  • As for structural system, which constitutes his construction, there are column inside dimension and span which constitutes plane, and as for constructions for section, there are C.H and slab, and as for constructive factors for envelope, there are window and closing panel of outer wall, and as for opening, there are punching window and wave window. With these constructive parts and opening of envelope, his construction composes volume and mass. The relation of structure and modulor which are shown in his later construction can be divided in two cases that modulor is directly and indirectly adapted for rate and measure calculation of the constructive body. As for indirectly adapted case, we can find it form most of his later construction, it is living place in which human beings life is, and it is adapted mainly for small space. In his construction, he tried to tell human scale and sense of musical rhythm through modulor. In other words, he played sense of space and musical scale by adapting regular and repetitive modulor of opening, and in small space for daily life, he made the size of space into the space which human can perceive. And, if we interpret mudulor in modern meaning, it is an establishment of radius of human act. And, we can make organic and harmonic design of space if we use modulor as origin of human centered measurement calculation, and if we adapt space after dividing by use.

The Effect of Halal Awareness on Purchase Intention of Halal Food: A Case Study in Indonesia

  • VIZANO, Nico Alexander;KHAMALUDIN, Khamaludin;FAHLEVI, Mochammad
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.4
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    • pp.441-453
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    • 2021
  • This study seeks to examine the effect of attitude, subjective norm, and perceived behavioral control on the purchase behavior of students enrolled in a private higher education establishment in Tangerang, Indonesia. This is a quantitative study and it employs samples by simple random sampling of 410 university students. The returned and valid questionnaire results totaled 261 samples. Data processing used the SEM method with SmartPLS 3.0 software. The findings of this study reveal that attitude, subjective norm, and perceived behavioral control have a significant effect on purchase intention. Meanwhile, purchase intention has a significant effect on working students' purchase behavior, and halal awareness had a moderating effect of purchase intention on purchase behavior. Purchasing interest has a positive effect on purchasing behavior, and this study proves that halal awareness is able to moderate the effect of purchase intention on purchasing behavior toward halal food products. The higher the awareness of halal products, the greater the relationship between buying interest and buying behavior of halal food. The results of this study also show the importance of paying attention to halal awareness factor in the form of increasing the relationship between buying interest and buying behavior of halal food products.

A Study on the Legal Issues on Chinese Security Law (중국의 독립보증에 관한 법률문제연구)

  • SONG, Soo-Ryun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.71
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    • pp.85-105
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    • 2016
  • Independent guarantee is new financial product developed in international commercial transaction. The nature of independent guarantee is an independent undertaking, which takes the form of documentary transaction. As long as the documents presented by the beneficiary are on their face complying with the terms and conditions of the guarantee, the guarantor is obliged to pay upon the complying presentation. Where parties choose to apply for issue of independent guarantee in international commercial transactions in China, Chinese court shall respect the autonomy of parties. If either the guarantor or the beneficiary is located outside of China, or the facts which cause the establishment, change or cancellation of independent guarantee relationship occurred outside of China, it shall be deemed as foreign related independent guarantee. If the interested parties requests for confirmation of the independence of foreign related independent guarantee, it shall be supported by Chinese court. However, parties dealing with Chinese domestic commercial transaction have not fully realized the severity of independent guarantee liability. The market credit is being cultivated and the financial innovation is being explored at present in China. In order to guard against the systematic and the regional financial risk, before relevant rules are promulgated, Chinese court shall not recognize the independence guarantees issued for the domestic commercial transaction, but treat it as joint liability surety.

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Exposure to Environmental Endotoxin and Health Effects (환경 중의 엔도톡신 노출 및 건강에 미치는 영향)

  • Park, Ju-Hyeong
    • Journal of Environmental Health Sciences
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    • v.40 no.4
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    • pp.265-278
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    • 2014
  • Microbes such as bacteria, fungi, archaea, protists, and viruses are ubiquitous and people are exposed to them continuously. Endotoxin is a component of the outer membrane of Gram-negative bacteria and a potent proinflammaotry substance. When a person is exposed to environmental endotoxin, an innate immune response is initiated upon the initial recognition and this response produces various inflammatory mediators and recruits inflammatory cells to the exposed tissues. A purified chemical form of endotoxin is called lipopolysaccharide (LPS), and the lipid A portion of the molecule is a biologically active moiety. Exposure to endotoxin may result in various complex health effects depending on time, route, and dose of exposure, as well as host susceptibility. Gene-environment interactions play important roles in health effects of endotoxin exposure, e.g. development or aggravation of asthma. To accurately assess exposure to endotoxin in environmental or epidemiologic studies, methods of sampling, extraction, and analysis must be carefully selected since the selected methods may substantially affect analytical results and there is no internationally-agreed standard method to date. The lack of a standardized method hampers the establishment of exposure-response relationships. While an internationally-agreed health-based exposure limit does not exist, the Dutch Expert Committee on Occupational Safety recently recommended $90EU/m^3$ as a health-based occupational exposure limit. The current article reviews various scientific issues on how we measure environmental endotoxin and the health effects of endotoxin exposure.

Analysis on the Results of the World Wide Rockwell Hardness Round Robin Test with Conical Indenters (로크웰 경도 국제비교교정 결과 분석)

  • Bahng, G.W.;Tak, N.H.;Polzin, T.
    • Journal of the Korean Society for Heat Treatment
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    • v.14 no.6
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    • pp.336-344
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    • 2001
  • For the establishment of the world wide unified scales of the Rockwell hardness test with conical indenters, round robin test was carried from 1998 to 2000. The pilot laboratory was MPA-NRW and 12 laboratories from 11 countries participated In this RRT. Rockwell hardness of 74 specially prepared blocks was measured for the scales of C, A, D, 45N, 30N, and 15N and the results were compared. It was found that the geometric form of indenter affects on the results very significantly and standardization in the measurement and evaluation of indenter should be established in short time for the reliable hardness measurement. KRISS showed good results in general for all of the ranges except 15N scale which showed relatively large difference compare to the mean value. It was concluded that poor control in loading velocity of the dash pot was the major reason.

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DETERMINATION OF THE 129I IN PRIMARY COOLANT OF PWR

  • Choi, Ke Chon;Park, Yong Joon;Song, Kyuseok
    • Nuclear Engineering and Technology
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    • v.45 no.1
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    • pp.61-66
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    • 2013
  • Among the radioactive wastes generated from the nuclear power plant, a radioactive nuclide such as $^{129}I$ is classified as a difficult-to-measure (DTM) nuclide, owing to its low specific activity. Therefore, the establishment of an analytical procedure, including a chemical separation for $^{129}I$ as a representative DTM, becomes essential. In this report, the adsorption and recovery rate were measured by adding $^{125}I$ as a radio-isotopic tracer ($t_{1/2}$ = 60.14 d) to the simulation sample, in order to measure the activity concentration of $^{129}I$ in a pressurized-water reactor primary coolant. The optimum condition for the maximum recovery yield of iodine on the anion exchange resins (AG1 x2, 50-100 mesh, $Cl^-$ form) was found to be at pH 7. In this report, the effect of the boron content in a pressurized-water reactor primary coolant on the separation process of $^{129}I$ was examined, as was the effect of $^3H$ on the measurement of the activity of iodine. As a result, no influence of the boron content and of the simultaneous $^3H$ presence was found with activity concentrations of $^3H$ lower than 50 Bq/mL, and with a boron concentration of less than 2,000 ${\mu}g/mL$.