• 제목/요약/키워드: Forensic service

검색결과 237건 처리시간 0.023초

SPE 및 GC/MS에 의한 혈액중 스트리크닌의 분석법 개발 및 검출사례 (Method Development and Validation of Strychnine in Blood by Gas Chromatography/Mass Spectrometry Using Solid Phase Extraction and its Application in Real Specimens)

  • 이종숙;염혜선;문성민;이상기
    • 약학회지
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    • 제57권2호
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    • pp.87-94
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    • 2013
  • An analytical methodology based on solid-space extraction (SPE) with with Bond Elut Certify cartridge (Varian, 130 mg) has been developed for the qualification and quantitation of strychnine in blood. After the elution layer was evaporated, the residue was reconstituted with methanol for GC/MS. Internal standard was used 10 mg/l dextromethorphan. Strychnine is a potent central nervous stimulant and convulsant, and an alkaloid found in seeds of Strychnos nux-vomica. It was used therapeutically to improve circulation and muscle tone in oral or intramuscular doses of 0.05~8 mg. The fatal dose of strychnine for humans is 50~100 mg. A man was found dead lying curled up the corner of the large room in a roof house after the fire fighter opened a locked door inside to put out the fire. The postmortem blood and gastric contents were analyzed for toxicological testing. Strychnine and brucine were detected using GC/MS first in gastric contents extracts. The contents of strychnine was 0.083 mg/l in heart blood, 0.088 mg/l in peripheral blood and 4.0 mg/kg in gastric contents, respectively. Method validation was carried out in terms of linearity, accuracy, precision (intraday, interday) in blood. The assay is linear over 0.05~10 mg/l ($r^2$=0.999). Limit of detection (LOD) and limit of quantitation (LOQ) in blood were determined 0.02 mg/l (S/N=3) and 0.07 mg/l (S/N=10), respectively. Accuracy (bias%) of strychnine with 0.1, 1 and 10 mg/l was 12.0% (n=6), 9.3% (n=6) and 6.9% (n=6), respectively. Intraday precision (CV%) of strychnine with, 0.1, 1 and 10 mg/l were 6.4%, 10.4%, 1.2% (n=6), respectively. Interday precision (CV%) of strychnine with 0.1, 1 and 10 mg/l over three days were 24.0%, 18.5%, 13.8% (n=18), respectively. Relative recovery with 0.1, 1 and 10 mg/l (in blood) were 114.9%, 99.3% and 87.4% (n=6), respectively. The described method can be applied in forensic toxicology to determine strychnine in blood samples.

엘러스-단로스 제4형 증후군 환자에서 발생한 대동맥 파열 ([Secondary publication] Sudden Aortic Rupture in Ehlers-Danlos Syndrome Type IV)

  • 백태화;김민정;기창석;박성환;이헌;김경열;최병하
    • The Korean Journal of Legal Medicine
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    • 제40권2호
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    • pp.61-64
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    • 2016
  • Ehlers-Danlos syndrome type IV (EDS IV) is a hereditary disorder of the connective tissue, characterized by easy bruising, thin skin with visible veins, and spontaneous rupture of the large arteries, uterus, or bowel. EDS IV is caused by mutations of the gene for type III procollagen (COL3A1), resulting in insufficient collagen production or a defect in the structure of collagen. EDS IV can have fatal complications such as the rupture of great vessels or organs, which can cause hemorrhaging and sudden unexpected death. Here, we report a case of a 43-year-old female who collapsed after a struggle with a neighbor. In this patient, the bifurcation of the bilateral common iliac artery ruptured, with no evidence of trauma, inflammation, or atherosclerosis. Genetic analysis of COL3A1 showed the presence of a c.2771G>A (p.Gly924Arg) mutation, which may be associated with EDS IV. The forensic pathologist should consider the possibility that the spontaneous visceral or arterial rupture was caused by EDS IV. Genetic analysis is not currently a routine procedure during autopsy. However, in this case, we suggest that the patient possibly had an underlying EDS IV condition, and we recommended family members of the deceased to seek genetic analysis and counseling.

선행 차량의 후진에 의한 저속 충돌 시 탑승자 경추 상해에 대한 연구 (Occupant Neck Injury Assessment Caused by Backward Movement of a Preceding Vehicle at a Low Impact Velocity)

  • 김성진;전우정;박우식;서영일;손권
    • 한국자동차공학회논문집
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    • 제21권3호
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    • pp.66-73
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    • 2013
  • This study assesses neck injury of occupants in a real traffic accident case that a preceding vehicle moved backward and impacted a parked vehicle at a low velocity. This case is different from a case of whiplash injury caused by rear impact on vehicle. The impact velocity was estimated from damages of the two vehicle bumpers and the displacement of the parked vehicle was also estimated from CCTV images. MADYMO simulation was performed based on the vehicle specifications and investigation report. The comparison of neck flexion moments with the corresponding injury criteria revealed that occupants of the parked vehicle might have hardly neck injury.

부가적으로 설치된 장치 결함으로 인한 차량화재 사고사례 분석 (Analysis of Vehicle Fire Accident Caused by Defect of Optionally Established Equipment)

  • 박남규;김진표;남정우;송재용
    • 한국안전학회지
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    • 제29권5호
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    • pp.40-46
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    • 2014
  • This paper deal with due to the additional equipment established on the vehicle fire accident cases. Recently, vehicle was recognized as other living spaces and it was increasing installation of additional devices such as a black box, multivision, additional battery and so on. However, these additional devices were established on the vehicle by non-specialists such as the general public user or manufacturing and distributors of additional devices since the vehicle factory. Resulting from the additional equipments due to installation errors in these additional equipments connected to the electrical wiring insulation damage or electrical breakdown occurs, and finally leading to a fire caused by the additional equipments. Therefore, additional equipment established on the vehicle due to a fire in order to prevent accidents during the manufacturing process of these devices are installed. If not installed unless the manufacturing process, the installation of additional equipments established by professional who knows the vehicle structure that will be able to prevent the fire.

발전소용 4.16 kV급 차단기에서 감전사고 사례 분석 (Analysis of Electric Shock Accident on 4.16 kV Class Circuit breaker for Power Plant)

  • 박남규;송재용;김진표;고재모
    • 한국안전학회지
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    • 제29권4호
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    • pp.54-60
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    • 2014
  • This paper describes electric shock accidents on a 4.16 kV class circuit breaker for power plant. Electric shock accidents mostly involve damage of human life, in comparison with electrical fire, rate of human death tend to be higher in electric shock accidents. Specially, in a high voltage facilities rate of human death comprised about 43.7% by electric shock accidents. If electric shock accidents happen in a 4.16 kV class circuit breaker for power plant, then the power plant discontinue power production. Electric shock accidents in a power plant have a great ripple effect such as an electric power shortage. In this paper, we analyzed electric shock accidents on a 4.16 kV class circuit breaker for power plant. From the analysis results, we confirmed a cause of electric shock accidents on a 4.16 kV class circuit breaker, it happened by defect of interlock equipment or occurrence of breakdown between first feeder contactor and shielding plate. In order to reduce electric shock accidents on a 4.16 kV class circuit breaker, the power plant should consider improvement of interlock equipment and insulation of feeder contactor in circuit breaker.

복원된 영상에 표기된 시간 정보에 의한 프레임 재정렬 기법 (Frame Rearrangement Method by Time Information Remarked on Recovered Image)

  • 김용진;이정환;변준석;박남인
    • 한국멀티미디어학회논문지
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    • 제24권12호
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    • pp.1641-1652
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    • 2021
  • To analyze the crime scene, the role of digital evidence such as CCTV and black box is very important. Such digital evidence is often damaged due to device defects or intentional deletion. In this case, the deleted video can be restored by well-known techniques like the frame-based recovery method. Especially, the data such as the video can be generally fragmented and saved in the case of the memory used almost fully. If the fragmented video were recovered in units of images, the sequence of the recovered images may not be continuous. In this paper, we proposed a new video restoration method to match the sequence of recovered images. First, the images are recovered through a frame-based recovery technique. Then, after analyzing the time information marked on the images, the time information was extracted and recognized via optical character recognition (OCR). Finally, the recovered images are rearranged based on the time information obtained by OCR. For performance evaluation, we evaluate the recovery rate of our proposed video restoration method. As a result, it was shown that the recovery rate for the fragmented video was recovered from a minimum of about 47% to a maximum of 98%.

스트리밍 음악 서비스의 저작권 보호를 위한 오디오 포렌식마킹 시스템 (Audio Forensic Marking System for Copyright Protection of Streaming Music Service)

  • 서용석;박지현;유원영
    • 디지털콘텐츠학회 논문지
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    • 제15권3호
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    • pp.357-363
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    • 2014
  • 본 논문에서는 인터넷 기반 스트리밍 음악 서비스의 저작권 보호를 위한 새로운 오디오 포렌식마킹 시스템을 제안한다. 제안한 방법에서는 스트리밍 서비스의 QoS 보장을 위해 고속으로 포렌식마크가 삽입된 MP3 파일을 생성한다. 이를 위하여 사전 포렌식마킹 과정을 두고, 사전 처리된 MP3 파일을 프레임 단위 조합 방식으로 사용자 정보가 삽입된 새로운 MP3 파일을 생성한다. 실험 결과, 제안한 방법은 강인성과 비인지성 및 실시간성 등에서 만족스러운 결과를 보였다. 또한 서버/클라이언트로 구현된 스트리밍 기반 오디오 포렌식마킹 시스템에서 실시간 삽입과 모바일 단말에서의 재생과 함께 삽입된 포렌식마크 검출이 가능함을 확인하였다.

전기장판 열선 결함에 의한 전기화재 원인분석 (Fire Cause Analysis on Electric Pad Due to Defect of Hot Wires)

  • 송재용;사승훈;남정우;김진표;조영진;오부열
    • 한국안전학회지
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    • 제27권2호
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    • pp.7-12
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    • 2012
  • This paper describes electrical fire on electric pad caused by defect of hot wires. We analyzed two type electric pad using by carbon type hot wire and magnetic shielded type hot wire. First, a carbon type hot wires electric pad is virtually impossible to connect hot wire as a method of electrical welding or soldering. In order to connect between hot wires, that has to splice carbon type material connector. If junction of hot wires was occurrence of poor connection on electric pad, it increase contact resistance on this junction point. With increasing contact resistance, junction of hot wires on electric pad generates local heating and finally leads to electrical fire. An electric pad using by a magnetic shielded type hot wire happened local heating on signal wire for sensing temperature-rise caused by applying current for magnetic shielded. With increasing local heating of signal wire, insulated coating of hot wire was melted. Finally the magnetic shielded type hot wire electric pad lead to electrical fire with breakdown between signal wire and hot wire. In this paper, we analyzed shape of damage in hot wire caused by electrical local heating and investigated fire cause on electric pad due to defect of hot wires.

바이메탈식 온도센서를 적용한 건조설비에서의 화재 위험성 연구 (Study of the Fire Risk Caused by the Use of a Bimetal type Thermometer in the Drying Equipment)

  • 박남규;김진표;남정우;박종택;송재용
    • 한국화재소방학회논문지
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    • 제31권3호
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    • pp.73-78
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    • 2017
  • 본 논문에서는 바이메탈식 온도센서를 적용한 건조설비에서의 화재 위험성에 대하여 연구하였다. 건조설비는 산업현장 등에서 광범위하게 사용되고 있으며, 건조 대상물이 가열될 때 발생하는 가연성 가스 및 증기에 의한 폭발 및 화재 등이 일어나기 용이하기 때문에 구조와 사용방법 등에 대한 규제가 엄격하게 이루어지고 있지만 부적합한 온도센서를 활용한 건조로 등의 내부온도 측정시 정확한 온도 측정이 이루어지지 못하는 경우에는 그만큼 화재 위험성이 증가하게 된다. 따라서 본 논문에서는 건조설비에 광범위하게 사용되고 있는 바이메탈식 온도센서의 구조를 분석하고, 측정 대상물의 성상에 따른 온도 측정 실험을 수행하였다. 측정 대상물에 따른 온도 측정 결과, 기체 및 고체에 대한 온도 측정에 있어서는 실제 온도에 비해 낮은 온도로 측정되었으며, 액체 대상물의 경우에는 비교적 정확한 온도 측정이 가능하였다. 이러한 실험 결과로부터 바이메탈식 온도센서는 기체 및 고체의 온도 측정에는 부적합하며, 액체의 온도 측정에 보다 적합한 특성을 나타내었다.

119 구급대원의 법의학 지식에 대한 연구 (Assessing the forensic knowledge of 119 emergency medical technicians)

  • 이희영;문준동
    • 한국응급구조학회지
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    • 제23권2호
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    • pp.75-86
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    • 2019
  • Purpose: It is crucial that 119 emergency medical technician (EMT) have adequate knowledge regarding forensic science. This study aimed to assess the forensic knowledge of EMTs in the Republic of Korea. Methods: This study was conducted on EMTs of five fire stations in D metropolitan city between August 6 and August 13, 2018. A questionnaire consisting of items on crime-related incident recognition (i.e., mechanical asphyxiation, trauma, sex crimes, and child abuse), forensic evidence management (i.e., evidence collection, preservation, and recording) was administered to the participants. Finally, 119 questionnaires were analyzed. Results: The ratio of correct answers for crime-related incidents recognition was 55.82%, which was lower than that for forensic evidence management(84.5%). In particular, the scores for the type of neck compression(16.5%) and wound assessment(44.0%) were low. The percentage of correct answers for forensic evidence management was 78.4% for evidence collection, 84.4% for evidence preservation, and 90.6% for evidence recording. Previous forensic education experience was not a significant variable. Conclusion: Specific and practical forensic science education on perception of crime-related incident, including asphyxia and wound identification, and forensic evidence collection is needed.