• Genomics & Informatics
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• v.6 no.3
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• pp.110-116
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• 2008

Blood pressure refers to the force exerted by circulating blood on the walls of blood vessels, and chronical elevation of blood pressure is known as hypertension. Although hypertension is affected by genetic and environmental factors, the genetic background of hypertension is not fully understood. One of the candidate genetic factors, Prostaglandin-endoperoxide synthase 2 (PTGS2), is a membrane-bound enzyme, catalyzing the conversion of arachidonic acid to prostaglandin, and recently SNPs of PTGS2 gene was associated with hypertension in Japanese population. Therefore the association of PTGS2 polymorphisms was investigated with blood pressure in healthy Korean subjects, 470 unrelated individuals randomly selected from Ansung and Ansan cohorts. The 25 SNPs of PTGS2 gene were identified by the sequencing analysis of 24 Korean samples. Among identified polymorphisms, three SNPs (rs689466, -1329A>G; rs5275, +6365T>C; rs4648308, +8806G> A) were selected for further association analysis, and rs689466 located in promoter region was associated with blood pressure as well as triglyceride level in the blood. By in silico analysis, rs689466 locates in v-Myb transcription factor binding site, and the v-Myb site disappears when the SNP is changed from A to G nucleotide. Individuals with A/G and G/G genotype in rs689466 have higher blood pressure than those with A/A genotype, and the regression p-value is 0.008 for systolic and 0.004 for diastolic blood pressure. In summary, the PTGS2 polymorphism (rs689466) is associated with blood pressure in Asian populations based on this and Japanese studies, shedding light on it as a genetic risk marker of hypertension.

• Journal of the Korean Society of Safety
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• v.26 no.4
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• pp.41-46
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• 2011

The purpose of this paper is to analyze the causes of accidents related to the 3 phase 170 kV gas insulated switchgear of a power system collected from accident sites to secure data for the prevention of similar accidents and provide important points of view regarding diagnosis for the prevention of accidents involving gas insulated switchgears. The analysis results of the causes of accidents involving gas insulated switchgears showed deformation of the manipulation lever installed at the S-phase, disconnection of the insulation rod connection, melting of the upper conductor, a damaged tulip, damage to the lower spacer and the spacer at the breaker, etc. It is believed from this result that the potential for accidents has expanded due to accumulated energy as a result of repeated deterioration. The carbonization depth of a GIS was formed near the screw (T2, T3) used to secure the lower pole of the S-phase tulip. It is not known what has caused the screws to be extruded and melted. However, it is thought that an unbalanced electromagnetic force, micro-discharge, surface discharge, etc., have occurred at that point. In addition, even though 16 years have passed since its installation, there was no installation defect, act of arson, accidental fire, etc. General periodical inspection and diagnosis failed to find the factors causing the accidents. As a system contained in a closed metal container, it has a high risk factor. Therefore, it is necessary to design, install and operate a GIS in accordance with the standard operational procedure (SOP). In addition, it is necessary to apply conversion technology for periodical SF6 gas analysis and precision safety diagnosis. It is expected that tracking and managing these changes in characteristics by recording the results on the history card will provide a significant accident prevention effect.

• Journal of Advanced Navigation Technology
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• v.27 no.4
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• pp.356-364
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• 2023

Sophisticated Air Navigation System has contributed to enhancing the capacity of airspace capacity, leading to an efficient airspace environment. However, it has acted as a factor increasing the probability of collision. When an aircraft fails to maintain vertical separation and instead exhibits lateral positional errors, it does not necessarily lead to a collision. However, as the lateral positional accuracy increases, the randomness of aircraft positions decrease, resulting in an elevated probability of collisions. Consequently, The International Civil Aviation Organization has introduced Strategic Lateral Offset Procedures(SLOP), intentionally deviating aircraft from the centerline of airways. Likewise, South Korea also operates Offset procedure. The Y579 was operated using the Offset before its conversion to a dual airway and the analysis of the Offset track revealed that it was being operated similarly to a unidirectional dual airway. This paper develops a safety assessment methodology applicable to unidirectional dual airways, and applies it to perform a safety assessment of the Y579 Offset procedure.

• Applied Chemistry for Engineering
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• v.18 no.4
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• pp.356-360
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• 2007

Recently, dye sensitized solar cells (DSSCs) composed of nanoporous $TiO_2$, light-sensitive dyes, electrolytes, and counter electrode have been received much attention. Nanostructured particles with higher surface area for the higher adsorption of Ru (II) dye are required to increase the quantity of light absorption. Also, it has been reported that the key factor to achieve high energy conversion efficiency in the photoelectrode of DSSC is the heat treatment of $TiO_2$ paste with acid addition. In this work, we investigated the influence of acid treatment of $TiO_2$ solar cell on the photovoltaic performance of DSSC. The working electrodes fabricated in this work were characterized by X-ray photoelectron spectroscopy (XPS), extended X-ray absorption fine structure (EXAFS), field emission scanning electron microscope (FE-SEM), and atomic force microscope (AFM). In addition, the influence of nanostructured photoelectrode fabricated with the acid-treated paste on the energy conversion efficiency was investigated on the basis of photocurrent-potential curves. It was found that the influence of acid-treated paste on the photovoltaic efficiency was significant.

• Korean Journal of Poultry Science
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• v.40 no.2
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• pp.121-127
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• 2013

This work was carried to evaluate production efficiency factor, carcass yield and meat quality with weeks of Large-type Korean native ducks. Korean native ducks (n = 90) from National Institute of Animal Science (RDA, Korea) were used in this work. Ninety ducks were divided into 6 groups (15 birds/group) and were fed with meat-type duck diets for 8 wk old. When ducks grew at specific wk (6, 7 and 8 weeks), 2 ducks per group were slaughtered at 6, 7 and 8 wk old. Production efficiency factor, carcass yield, partial meat and meat quality were researched in this work. There was no significant difference on livability with weeks, but body weight at 7 and 8 wk old was higher than that at 6 wk old (P<0.05). Feed conversion ratio at 6, 7 and 8 wk old were 2.25, 2.69 and 3.21, respectively, so there was significant difference with weeks (P<0.05). Production efficiency factor at 6, 7 and 8 wk old were 256.6, 199.8 and 153.0, respectively, so there was significant difference with weeks (P<0.05). Carcass yield at 8 wk old was higher than that at 6 and 7 wk old as 73.5% (P<0.05). Lightness at 6, 7 and 8 wk were 41.8, 39.0 and 38.1, respectively, and that at 6 wk old was the higher than other weeks (P<0.05). There was no significant difference on redness at 6, 7, and 8 wk old (P>0.05) and yellowness at 8 wk old was higher compared to other weeks (P<0.05). Cooking loss was the highest at 6 wk old as 31.6%, but water holding capacity was the highest at 8 wk old (P<0.05). There was no significant difference on shear force among weeks. pH at 6 wk old was the lower than that of other weeks as 5.84. Moisture content significantly decreased with weeks (P<0.05) and fat content at 8 wk was the highest as 1.88% (P<0.05). Protein content significantly increased with weeks until 20.9% at the age of 8 wk (P<0.05). Ash content at 7 and 8 wk old was the higher than that at 6 wk old (P<0.05). There was no significant difference on juiciness, tenderness, and flavor with weeks. Finally, these results may provide that shipping time at 7 wk old preferred to that at 6 and 7 wk old, but further research was needed because of deficiency of data.