• 한국초지학회:학술대회논문집
• /
• 한국초지조사료학회 2005년도 학술심포지엄, 제43회 학술발표회
• /
• pp.188-189
• /
• 2005

• 대한수의학회지
• /
• 제59권1호
• /
• pp.43-45
• /
• 2019

To establish appropriate conditions for a disinfectant efficacy test at subzero temperatures, this study examined mixtures of frozen foot-and-mouth disease virus or avian influenza virus solutions and disinfectant diluents at $-5^{\circ}C$ and monitored temperature and freezing status of an anti-freezing diluent (AFD, 15% ethanol + 30% propylene glycol + 55% distilled water) over time at various subzero temperatures. Viral solutions and disinfectant diluents froze before the mixtures reached $-5^{\circ}C$, whereas the AFD was not frozen at $-30^{\circ}C$. The times taken for the AFD to reach -10, -20, -30, and $-40^{\circ}C$ from room temperature were 36, 39, 45, and 48 min, respectively.

• 한국정보통신학회:학술대회논문집
• /
• 한국정보통신학회 2016년도 추계학술대회
• /
• pp.493-495
• /
• 2016

농축산 전염병 위기완화서비스 모델구조 및 용용모델은 모바일, 인터넷등 네트워크 기반에서 전염병과 같은 위기 발생 지점과 위기 영향 영역 사이에 위기완화 및 위기 통제기능을 두어 위기완화를 대처해 나가는 체계 및 응용모델을 제시한다.

• Clinical and Experimental Pediatrics
• /
• 제53권5호
• /
• pp.639-643
• /
• 2010

Purpose: Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have been reported. The clinical characteristics in children with neurologic manifestations of EV71 were studied in Ewha Womans University Mokdong Hospital. Methods: Examinations for EV71 were performed from the stools, respiratory secretion or CSF of children who presented neurologic symptoms associated with HFMD by realtime PCR. Clinical and radiologic data of the patients were collected and analyzed. Results: EV71 was isolated from the stool of 16 patients but not from respiratory secretion or CSF. Among the 16 patients, meningitis (n=10) was the most common manifestation, followed by Guillain-Barre syndrome (n=3), meningoencephalitis (n=2), poliomyelitis-like paralytic disease (n=1), and myoclonus (n=1). Gene analysis showed that most of them were caused by EV71 subgenotype C4a, which was prevalent in China in 2008. Conclusion: Because EV71 causes severe complications and death in children, a surveillance system to predict upcoming outbreaks should be established and maintained and adequate public health measures are needed to control disease.

• 한국측량학회지
• /
• 제31권3호
• /
• pp.209-219
• /
• 2013

역학 모델은 질병 확산에 대한 시뮬레이션 및 관련 방역대책을 수립하는데 유용하며, 개체들의 접촉을 통해 전파되는 질병의 공간 확산에 대한 자세한 이해를 가능하게 한다. 이 연구에서는 공간에서 개체 간의 상호작용에 의한 결과로 구제역 전염병의 확산을 시뮬레이션하기 위해 GIS와 통합된 행위자 기반 공간 모델을 제안하고자 한다. 설계된 모델은 모집단, 시간, 공간이라는 세 요소를 고려하여 축산장 간의 간접접촉을 묘사하였다. 모집단의 역학관계는 2010년 경상북도 안동시에서 발생한 구제역 사례를 기준으로 하였으며, 도로를 주행하는 차량에 의한 간접접촉으로 전염병이 전파하는 것으로 설계하였다. 확산 모델은 구제역 전파 확률, 질병에 대한 여러 상태, 질병의 확산 시간, 감염률, 잠복기 및 기타 매개변수 간의 관계를 수식으로 표현하였다. 모델을 이용하여 구제역 발생 상황을 예측하면서 다양한 시나리오를 적용해서 모의실험하였다. 구제역 발생 상황에서 방역 전략을 선정하기 위해 제시된 방법을 이용하여 방역조치를 다양하게 실험하는 것은 구제역 확산을 통제하는 데 중요한 역할을 할 것으로 기대된다.

• 대한족부족관절학회지
• /
• 제21권1호
• /
• pp.12-16
• /
• 2017

Purpose: Anterior drawer and varus stress radiographs are commonly to diagnose chronic lateral ankle instability. We compared the preoperative stress radiographs with the intraoperative radiographs under anesthesia to determine the accuracy and efficacy of stress radiographs in an outpatient clinical environment. Materials and Methods: Data was collected from patients who underwent a modified $Brostr{\ddot{o}}m$ operation for painful chronic unilateral lateral ankle instability between January 2014 and June 2016. Subjects were divided into three groups-complete tear, partial tear, and instability without rupture-according to the status of preoperative MRI findings of the anterior talofibular ligament. The anterior drawer and varus stress radiographs were taken preoperatively and intraoperatively under anesthesia. Results: Ninety-six patients, with a mean age of 29.63 years, were enrolled. There were 39, 46, and 11 patients in the complete tear, partial tear, and instability without rupture groups, respectively. On the anterior drawer and varus stress radiographs of the affected limb, talar anterior translation and varus tilting were significantly increased by 2.56 mm and $2.0^{\circ}$. The gaps between the unaffected limbs were also increased by 2.47 mm and $1.32^{\circ}$ after anesthesia. Although the stress radiographs were taken under anesthesia, the results were often smaller than the diagnostic value. Conclusion: Stress radiographs for painful chronic lateral ankle instability taken at the outpatient clinic might be inaccurate for diagnosis.

• Journal of Microbiology and Biotechnology
• /
• 제22권7호
• /
• pp.883-888
• /
• 2012

The efficacy of cowdung, Bangladesh Institute of Nuclear Agriculture (BINA)-biofertilizer, and Bangladesh Agricultural University (BAU)-biofungicide, alone or in combination, was evaluated for controlling foot rot disease of lentil. The results exhibited that BINA-biofertilizer and BAU-biofungicide (peat soil-based Rhizobium leguminosarum and black gram bran-based Trichoderma harzianum) are compatible and have combined effects in controlling the pathogenic fungi Fusarium oxysporum and Sclerotium rolfsii, which cause the root rot of lentil. Cowdung mixing with soil (at 5 t/ha) during final land preparation and seed coating with BINA-biofertilizer and BAU-biofungicide (at 2.5% of seed weight) before sowing recorded 81.50% field emergence of lentil, which showed up to 19.85% higher field emergence over the control. Post-emergence deaths of plants due to foot rot disease were significantly reduced after combined seed treatment with BINA-biofertilizer and BAU-biofungicide. Among the treatments used, only BAU-biofungicide as the seed treating agent resulted in higher plant stand (84.82%). Use of BINA-biofertilizer and BAU-biofungicide as seed treating biocontrol agents and application of cowdung in the soil as an organic source of nutrient resulted in higher shoot and root lengths, and dry shoot and root weights of lentil. BINA-biofertilizer significantly increased the number of nodules per plant and nodules weight of lentil. Seeds treating with BAU-biofungicide and BINA-biofertilizer and soil amendment with cowdung increased the biomass production of lentil up to 75.56% over the control.

• Vascular Specialist International
• /
• 제34권4호
• /
• pp.109-116
• /
• 2018

Purpose: Diabetic foot wound (DFW) is known as a major contributor of nontraumatic lower extremity amputation. We aimed to evaluate overall amputation rates and risk factors for amputation in patients with DFW. Materials and Methods: From January 2014 to December 2017, 141 patients with DFW were enrolled. We determined rates and risk factors of major amputation in DFW and in DFW with peripheral arterial occlusive disease (PAOD). In addition, we investigated rates and predictors for amputation in diabetic foot ulcer (DFU). Results: The overall rate of major amputation was 26.2% in patients with DFW. Among 141 DFWs, 76 patients (53.9%) had PAOD and 29 patients (38.2%) of 76 DFWs with PAOD underwent major amputation. Wound state according to Wagner classification, congestive heart failure, leukocytosis, dementia, and PAOD were the significant risk factors for major amputation. In DFW with PAOD, Wagner classification grades and leukocytosis were the predictors for major amputation. In addition, amputation was performed for 28 patients (38.4%) while major amputation was performed for 5 patients (6.8%) of 73 DFUs. Only the presence of osteomyelitis (OM) showed significant difference for amputation in DFU. Conclusion: This study represented that approximately a quarter of DFWs underwent major amputation. Moreover, over half of DFW patients had PAOD and about 38.2% of them underwent major amputation. Wound state and PAOD was major predictors for major amputation in DFW. Systemic factors, such as CHF, leukocytosis, and dementia were identified as risk factors for major amputation. In terms of DFU, 38.4% underwent amputation and the presence of OM was a determinant for amputation.

• IMMUNE NETWORK
• /
• 제13권4호
• /
• pp.157-162
• /
• 2013

Application of vaccine materials through oral mucosal route confers great economical advantage in animal farming industry due to much less vaccination cost compared with that of injection-based vaccination. In particular, oral administration of recombinant protein antigen against foot-and- mouth disease virus (FMDV) is an ideal strategy because it is safe from FMDV transmission during vaccine production and can induce antigen-specific immune response in mucosal compartments, where FMDV infection has been initiated, which is hardly achievable through parenteral immunization. Given that effective delivery of vaccine materials into immune inductive sites is prerequisite for effective oral mucosal vaccination, M cell-targeting strategy is crucial in successful vaccination since M cells are main gateway for luminal antigen influx into mucosal lymphoid tissue. Here, we applied previously identified M cell-targeting ligand Co1 to VP1 of FMDV in order to test the possible oral mucosal vaccination against FMDV infection. M cell-targeting ligand Co1-conjugated VP1 interacted efficiently with M cells of Peyer's patch. In addition, oral administration of ligand-conjugated VP1 enhanced the induction of VP1-specific IgG and IgA responses in systemic and mucosal compartments, respectively, in comparison with those from oral administration of VP1 alone. In addition, the enhanced VP1-specific immune response was found to be due to antigen-specific Th2-type cytokine production. Collectively, it is suggested that the M cell-targeting strategy could be applied to develop efficient oral mucosal vaccine against FMDV infection.

• 지질공학
• /
• 제23권4호
• /
• pp.427-434
• /
• 2013

구제역 매몰지에서 발생하는 침출수는 지하수, 호소수 및 하천수 등의 자연수에서 나타나는 유기물질의 성상(친수성 유기물질: 22~27%)과 달리 친수성유기물질을 44~50%로 포함하고 있었다. 자연수에서는 유기탄소가 미생물의 대사 등에 의해 감소되는 경향을 나타낸다. 하지만, 매몰 초기에 발생하는 구제역 침출수(leachate-1, 2)에서는 RTOC와 RDOC의 농도가 초기 TOC, DOC 농도보다 높게 나타나는 특성이 있다. 매몰시간이 경과하면서 RTOC와 RDOC는 초기 TOC와 DOC보다 낮게 검출되었다. 구제역 침출수 중 386일이 경과한 leachate-6의 RDOC는 RTOC 중에 91%를 차지하였다. 이것은 안정화된 매몰지 환경에서도 침출수 중에는 여전히 미생물 등의 활동에 의해 제거되기 어려운 형태의 난분해성 유기물질이 유기물질의 대부분을 차지하고 있음을 알 수 있다. 따라서 구제역 침출수의 난분해성 유기물질의 검출수준과 성상은 지표수 및 지하수에 대한 영향을 파악하는 정보로서 유효하며, 침출수 내 환경을 이해하는 데에도 기여할 것으로 기대된다.