• Bulletin of the Korean Chemical Society
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• 제27권10호
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• pp.1567-1571
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• 2006

Synthetic color additives approved for general food use are sixteen in European Union, seven in U. S. A. and twelve in Japan. Twelve food dyes were examined for their inhibitory potency against human protein tyrosine phosphatases (PTPases). Half of the food colorants inhibited PTPases significantly and three of them were potent inhibitors with low micromolar IC50 values. Also examined were the synthetic dyes structurally similar but not allowed in food. Some of them were potent inhibitors of PTPases. Considering the importance of PTPases in cellular signal transduction, inhibition of PTPases by food colorants might cause harmful effects in human health.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.328.3-329
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• 2002

A convenient bioassay of nerve growth factor(NGF) is essential for assessing its potency during the course of product development and quality controls afterwards. We have set up a cell-based bioassay for determining the potency of recombinant NGF using rat pheochromocytoma (PC12) cells. Cell survival was measured by monitoring the reduction of the alamarBlue$^{TM}$ dye by living cells. (omitted)d)

• 한국축산식품학회지
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• 제28권1호
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• pp.63-68
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• 2008

본 연구에서는 근적외선 분광광도계를 이용하여 원유의 체세포수 측정에 필요한 최적의 색소를 선정하기 위하여 eosin-Y, methyl red, methylen blue, resazurin 및 amido black 10B등의 5가지 색소를 0.01%첨가 후 근적외선 분광광도계를 이용하여 400-2,500 nm 영역에서 측청하였으며, PLS(partial least squar)분석 결과는 다음과 같다. 교정부 모델에서의 상관도는 raw milk 0.78, eosin-Y 0.65, methyl red 0.63, methylen blue 0.65, resazurin 0.98 그리고 amido black 10B는 0.99 였다. 또한, 검증부 모델에서의 상관도는 raw milk 0.49, eosin-Y 0.21, methyl red 0.36, methylen blue 0.47, resazurin 0.95 그리고 amido black 10B는 0.98 였다. 위 결과를 종합해 보면, amido black 10B를 첨가한 경우 검증부 모델의 상관도는 0.98, 검증부 오차(SEP)는 0.09로 가장 우수한 결과를 보였다.

• 한국염색가공학회지
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• 제30권2호
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• pp.141-149
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• 2018

This study aimed to investigate the efficacy of eco-friendly leather dyeing by utilizing food wastes. Natural dyeing of eel skin was attempted using onion peels which have been used commonly for natural dyeing of textile fabrics. Eel skin is a by-product from fishery processing and is used mainly for making leather products. The colorant was extracted from onion peels in boiling water, concentrated, and freeze-dried. Dyeing of eel skin was carried out to study the effects of dyeing conditions, mordant type and mordanting method on dye uptake, color change, drape stiffness and colorfastness. The optimum dyeing conditions were $60^{\circ}C$ of dyeing temperature, 60min of dyeing time at 1:100($H_2O$ 90%: ethanol 10%) of bath ratio. The onion peels produced yellowish color on eel skin. The pre-mordanting was effective than the post-mordanting. As a result of the drape stiffness measurement, the Fe-mordanted sample was somewhat stiffer comparing to other mordanted samples. The light fastness of the non-mordant dye was excellent in 3-4 grade. Drycleaning fastness and rubbing fastness showed excellent results, but fastness was not significantly improved by mordanting.

• Journal of Nutrition and Health
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• 제14권1호
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• pp.26-33
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• 1981

Crocin was extracted from Gardenia fructus in order to manufacture a natural food dye. In the extraction and purification process methanol and ethanol were used as the most Suitable solvent selected in preliminary test and 9.28%g/100g of Cretin product in 99.89% of purity was acquired. The lethal dose of Cretin administered in mouse by intra peridoneal was 5.36g/kg which is much lower toxic than any other. The toxic dose which caused diarrhoea in rat was 2.55g/kg and maximum no effect level was found to be 272mg/kg. From the $1%{\sim}2.5%$ content of Crocin in rat diet reduction of body weight appeared and GTP and GOT (Transaminase) value in creased significantly. Crocin showed a good properties of tolerating acid, alkali, sunlight, reductant, oxidant, and salt compared with tar dyes. The range from 100 ppm to 500ppm bring out bright $yellow{\sim}orange$ color, the most effective color, with a good solubility in water-slightly in oil. The acceptable daily intake of crocin was calculated as 2.72mg/kg based on maximum no effect dose (2% additive dose).

• 한국식품과학회지
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• 제29권1호
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• pp.21-25
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• 1997

소포장 김치의 발효, 숙성정도를 연속적으로 신속하게 감지할 수 있는 기술을 개발하고자 색 지시계를 적용하였다. $CO_2$ 흡착제/발색시약의 혼합물로 구성된 지시계를 포장재에 도입하여 화학반응에 의한 색깔 변화와 저장 중 김치의 pH, 산도 변화를 측정 비교하므로서 숙성도를 감지하였다. 김치의 발효 숙성이 진행되면서 포장재 내부에 부착되어 있던 지시계 BP와 MR은 초기의 하늘색에서 보라색으로, 연한 노란색에서 빨간색으로 점차 색이 변하였으며, 이러한 지시계의 색 변화는 저장온도에 관계없이 pH 또는 산도 변화와 높은 상관관계를 가지므로서 김치의 숙성정도를 잘 나타내었다. 결과적으로 상품 김치의 저장 유통과정에서 포장을 뜯지 않고도 내용물의 숙성도를 육안으로 감지할 수 있는 숙성 감지용 지시계의 적용 가능성을 확인할 수 있었다.

• 한국식품과학회지
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• 제25권1호
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• pp.69-77
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• 1993

미생물막 유동층 반응기로 염료공장 폐수의 유기물 처리효율을 고찰하였다. 공장폐수를 2배, 3배 및 6배 희석하여 처리하였던 바, 각 희석배율 모두 F/M비가 0.2에서 0.3으로 증가할 때 처리효율이 급격히 낮아졌다. 한편, 같은 F/M비에서는 희석율이 높을수록 처리효율이 높았으며 수리학적 체류시간이 증가함에 따라서 처리효율도 증가하였다. 6배 희석시 F/M비가 0.2 이하에서 BOD 처리효율이 $90{\sim}97%$로 가장 좋았다. 또 반응기 설계를 위한 통역학적 계수 Y, $k_b$값 및 상관계수 r은 2배 희석시 $Y=0.3365\;k_d=0.03782\;day^{-1}\;r=0.997$, 3배 희석시 $Y=0.3341\;k_d=0.0275\;day^{-1}\;r=0.996$ 및 6배 희석시는 $Y=0.5460\;k_d=0.03434\;day^{-1}\;r=0.998$로 나타났다.

• 한국염색가공학회지
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• 제7권1호
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• pp.72-79
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• 1995

The effect of copper sulfate/thiourea on the diffusion and the dye exhaustion of two dyes, C. I. Acid Orange 7 and C. I. Food Yellow 3 in nylon 6 fiber has been studied. The results obtained from the experimetal are as follows : 1) Copper sulfate reacted with thiourea at constant temperature and then generated the colorless trasparent coordination compound, and then combinated end group of carboxyl of nylon 6 fiber. 2) The coordination compound [$Cu_{2}$($TU_{6}$)] ($(SO_{4})_2$) is conducted at pH 5-6 in solution intensity and repulsed the sulfonic acid group of dyes, and therefore the diffusion of dyes is restraint. 3) Dye uptake and diffusion coefficient were decreased in the order of untreated > copper sulfate/thiourea-treated > tannin-treated.

• 한국의류학회지
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• 제31권9_10
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• pp.1408-1417
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• 2007

In Korea, to deal with the housing needs of the elderly, the government operates free nursing homes and residential homes. And to deal with the needs for daily necessities, imported products or products for the disabled have been supplied for the elderly. The government has recognized the importance of silver industry in this rapidly aging society and has established strategies to vitalize industries related to seniors to deal with the seniors' need for food, clothing, and shelter. This study examined the necessity of nursing home gowns, and the development of nursing home gowns that are environmentally friendly, beautiful and functional for the new silver generation. For this study, literature review and Internet search were conducted regarding the status of silver fashion, necessity of nursing home gowns, emergence of new silver generation and change in lifestyle, and value and utilization of natural dye and traditional patterns. To produce nursing home gowns, fabric was dyed using fermented indigo dying, and 3 styles of nursing home gowns for each gender were designed in consideration of seasons. Lastly, these gowns were evaluated by fashion experts, medical personnel, hospital gown and silver wear experts, and natural dye experts. The results showed that the traditional Korean designs developed in this study were excellent and the fermented indigo dye was appropriate for the nursing home gowns. The development of nursing home gowns in this study will be utilized as basic material for the development of silver wear and nursing home gowns to improve the quality of life for the seniors.

• Journal of the Korean Wood Science and Technology
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• 제34권3호
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• pp.64-72
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• 2006

참식나무(Neolitsea sericea Koidz) 추출물의 염색특성을 구명하기 위하여 수피의 열수추출물에 대해 검토했다. 참식나무 수피의 열수추출물로부터 디에틸에테르와 에틸아세테이트로 분획하여 얻은 fraction을 TLC 및 column chromatography 처리하여 2개의 물질을 단리하였다. 기기분석을 통하여 단리물질의 구조를 해석한 결과, 알칼로이드 계열의 4H-dibenzoquinoline-2,10-diol, 5,6,6a,7-tetrahydro-1,9-dimethoxy-6-methyl (화합물I)과 리그난 계열의 lyoniresinol (화합물II)로 동정되었다. 이들 물질이 염색에 관여하는지 확인하기 위하여 HPLC를 사용하여 검토한 결과, 화합물(I)과 화합물(II)의 retention time이 참식나무 추출물 염색액 및 탈염액의 에틸아세테이트 fraction 중 주성분 피크의 retention time과 동일한 결과를 보였다. 따라서 화합물(I)과 화합물(II)가 참식나무 수피의 주요 염착물질임을 확인할 수 있었다.