• Fisheries and Aquatic Sciences
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• 제17권4호
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• pp.449-454
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• 2014

The effects of food deprivation and feeding ratio on the growth, feed utilization and body composition of juvenile olive flounder Paralichthys olivaceus were investigated in 810 juvenile fish averaging 6.4 g in weight randomly distributed in 27 400-L flow-through tanks. A 3 [food deprivation: 8-week feeding without food deprivation (8W), 7-week feeding after 1-week food deprivation (7W) and 6-week feeding after 2-week food deprivation (6W)]${\time}3$ (feeding ratio: 100%, 95% and 90% of satiation, hereafter denoted by 100, 95 and 90, respectively) factorial design was applied. The weight gain of the fish was significantly affected by both food deprivation and feeding ratio. The weight gain of the fish under the 8W-100 treatment was higher than that of those under the 7W-95, 7W-90, 6W-100, 6W-95 and 6W-90 treatments, but did not differ from those of fish under the 8W-95, 8W-90 and 7W-100 treatments. The specific growth rate (SGR) and the feed intake of the fish were affected by both food deprivation and feeding ratio. However, the feed conversion ratio (FCR) was unaffected by both food deprivation and feeding ratio. The protein efficiency ratio (PER) was affected by the feeding ratio, but not by food deprivation. The protein retention (PR) was affected by food deprivation, but not by feeding ratio. Juvenile olive flounder subjected to 1-week food deprivation at 100% satiation (7W-100 treatment) achieved full compensatory growth.

• International Journal of Industrial Entomology and Biomaterials
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• 제9권1호
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• pp.111-115
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• 2004

Nutrition plays an important role in maintaining the larval health, cocoon quality and reproductive potential in Antheraea mylitta D. Nutritional efficiency greatly influenced if food is not adequate and of quality. A. mylitta silkworms were subjected to food deprivation for the period of 0 hr to 12 hrs /day to assess its effect on various nutritional parameters and indices, and its manifestation at different levels. Food ingesta, digesta, gain in body weight declined significantly at each level of deprivation, so also food utilization efficiency like consumption index (CI), growth rate (GR), approximate digestibility (AD), and efficiency of conversion of ingested food (ECI). This stress leads to decline in mean daily food ingesta by 16.73% to 39.76% and digesta by 28.98% to 54.01 % following a significant reduction in average daily body weight gain (27.68% to 55.09%). Food deprivation a1so caused significant loss in the silk gland weight, cocoon and shell weight (14.37% to 53.69%), lowered the fecundity (35.86 % to 83.59%) and in number of eggs laid per gram body weight, but simultaneously the number of non-chorionated eggs increased significantly.

• 한국수산과학회지
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• 제41권2호
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• pp.125-133
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• 2008

To investigate the effect of repeated food deprivation and refeeding on the hyperphagia, compensatory growth, feed efficiency, body composition, hepatosomatic index (HSI), and survival rate of the juvenile olive flounder Paralichthys olivaceus, an experiment was conducted for 90 days. Feeding treatments consisted of the following five regimes for 90 days from August to October, 2005: C: daily satiation feeding (control), S1: 1-day satiation feeding after 1-day food deprivation, S2: 1-day satiation feeding after 2-day food deprivation, S3: 1-day satiation feeding after 3-day food deprivation and S4: 1-day satiation feeding after 4-day food deprivation, respectively. Although the monthly feed intake (MFI) of the control was significantly higher than that of all of the starved groups, the daily feed intake (DFI) was more higher in S1, S2, and S3 than that in the control as a result of hyperphagia after starvation. While the feed efficiency in the summer (to day 30) decreased in all of the starved groups with prolongation of the starvation period, the feed efficiency in the autumn (to day 90) was increased with prolongation of the starvation period. The whole body proximate composition and HSI were also affected by starvation. The crude protein, lipid, and HSI decreased with prolongation of the starvation period, whereas the crude ash and moisture increased. The growth rate and condition factor also decreased in proportion to the starvation period. The survival rate was highest in the control and was the lowest in S4. In this study, although hyperphagia occurred in the deprived groups, we knew that the compensatory growth did not always occur.

• 대한가정학회지
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• 제35권2호
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• pp.49-64
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• 1997

The purpose of this study is to classify the patterns of consumption deprivation and to compare the level of consumption deprivation by them. For empirical analysis, this study used the data on 563 households in the city of Inchon collected by the researchers through interviews. The statistical methods used in this study were cluster analysis, oneway ANOVA, and crosstabs. four clusters were classified: 'Overall satisfied Pattern (OSP)', 'Food satisfid with Others deprived Pattern (FS-ODP)', Food Extremely deprived with Food Deprive Pattern (HED-FDP)'. Those I FED-HSP tended to be old aged, and those in GED-FDP tended to be urban unstable workers. The results imply that welfare policy for urban poor households should be differentiated by the characteristics of consumption of each pattern of consumption deprivation.

• Food Science and Biotechnology
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• 제16권4호
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• pp.632-635
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• 2007

This study examined the neuroprotective effect of scopoletin from Angelica dahurica against oxygen and glucose deprivation-induced neurotoxicity in a rat organotypic hippocampal slice culture. Scopoletin reduced the propidium iodide (PI) uptake, which is an indication of impaired cell membrane integrity. In addition, it inhibited the loss of NeuN, which represents the viability of neuronal cells. The results suggests that scopoletin from A. dahurica protects neuronal cells from the damage caused by oxygen and glucose deprivation.

• 한국노년학
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• 제38권2호
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• pp.271-290
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• 2018

이 연구는 사회경제적 박탈 경험이 노인의 자살 생각에 미치는 영향을 분석하는 것을 목적으로 한다. 분석 자료는 한국복지패널 9차년도 자료를 사용하였으며, SPSS를 활용하여 빈도분석, 평균차이분석, 상관분석, 로지스틱 회귀분석 등을 실시하였다. 주요 분석결과는 다음과 같다. 첫째, 공적연금을 받지 못했던 경험, 근로능력이 있으나 실업 상태였던 경험, 경제적 어려움으로 균형 있는 식사를 할 수 없었던 경험, 먹을 것이 떨어졌는데도 더 살 돈이 없었던 경험 등의 순으로 박탈 빈도가 높았다. 둘째, 배우자가 없는 경우, 학력과 소득수준이 낮을수록 자살 생각이 높은 것으로 나타났다. 셋째, 돈이 없어서 본인이나 가족이 병원에 갈수 없었던 경험, 2달 이상 집세가 밀렸거나 집세를 낼 수 없어 집을 옮긴 경험, 먹을 것을 살 돈이 없어 균형 있는 식사를 할 수 없었던 경험, 공과금을 기한 내 납부하지 못한 경험, 근로능력이 있으나 직업을 갖지 못한 경험, 경제적인 어려움 때문에 먹을 것이 떨어졌는데도 더 살 돈이 없었던 경험 등이 노인의 자살 생각에 통계적으로 유의미한 영향을 미치는 것으로 나타났다. 이러한 연구 결과를 토대로 이 논문은 의료급여 사례관리 확대, 노인 주거급여 및 정주 여건 개선, 노인 식생활실태 조사 강화, 노인 공과금 지원 방안 확대 등의 정책 방안을 제시하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제17권2호
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• pp.271-277
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• 2004

The purpose of this experiment was to study the feeding behavior and running speed under various feed deprivation lengths and social environments. Three trials were conducted. Trial 1: ten pigs were trained individually to run a course and eat their feed at the end of the course. The pigs were deprived feed for 1, 5, 10 or 20 h. Trial 2: 1. Two pigs ran and ate together. Both pigs had 5 h of feed deprivation before the run (D5). 2. Two pigs ran and ate alone, but both pigs had 5 h of feed deprivation before the run (S5). 3. Two pigs ran and ate together. Both had 1 h of feed deprivation before the run (D1). 4. Two pigs ran and ate alone and both pigs had 1 h of feed deprivation before the run (S1). 5. Two pigs ran together, one had 5 h of feed deprivation, and the other had 1 h of feed deprivation before the run (51). Trial 3: 1. On the 1st day 5 pairs of pigs had 5 h feed deprivation and could eat feed together at (B) point (D1). 2. On the 2nd day the pigs ran and ate alone at (B) point after 5 h of feed deprivation. Feed was obtainable (D2). On the 3rd to 6th days, the pigs ran in pairs after 5 h of feed deprivation and only the dominant pig ate feed at point (B). The inferior pig was chased back to room and fed there. This stage was continued for four consecutive days, d 3 to 6. In trial 1, the running speed of pigs increased with the length of feed deprivation until 10 h, then being stable afterwards. Total feeding time increased with the length of feed deprivation (p<0.001). Eating speed did not increase with the length of feed deprivation (p>0.05). In trial 2, nine of ten pigs in treatment D5 ran faster than those in S5. Seven of the ten pigs in treatment S1 ran faster than those in treatment D1. The pigs in treatment D5 had significantly higher feed intake (p<0.001) and eating speed (p<0.05) than the pigs in other treatments. In trial 3, there were significant differences on running speed between D1 and D6 (p<0.01) and between D2 and D1, D3, D4 and D5. The inferior pig ran faster in D2 but from 3 to 6 it was the dominant pig that showed the greatest speed in completing the whole course. The results demonstrated that the pigs with low feeding motivation may cause low running speed to feed and low feed intake of the neighbor when compared with pigs kept individually.

• 한국식품영양과학회지
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• 제42권8호
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• pp.1167-1174
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• 2013

암세포를 포함한 생체 내 빠른 분열을 요구하는 세포 집단에서 세포 내 구성요소 및 에너지원으로서 글루타민의 요구량이 증대되지만, 종양세포의 글루타민 의존적 대사작용에 관한 기전은 여전히 잘 알려진 바 없다. 본 연구에서는 LnCaP 전립선 암세포의 이동성 및 침윤성에 미치는 글루타민 결핍효능을 조사하였다. 본 연구의 결과에 의하면 LnCaP 세포에서 글루타민 결핍에 의하여 세포의 이동성 및 세포의 침윤성이 현저하게 억제되었으며, 이러한 이동성 및 침윤성 억제는 TIMPs의 발현 증대에 의한 MMPs의 발현 감소 및 그들의 효소적 활성 저하와 연관성이 있었다. 또한 글루타민이 결핍된 조건에서 배양된 LnCaP 세포에서 TER의 현저한 증가가 관찰되었는데, 이는 TJs의 조절인자인 claudin family 발현의 차단에 의한 것으로 생각되어진다. 본 연구의 결과에 의하면 암세포의 증식에서 글루타민의 결핍은 TJ의 결합력 증대와 MMPs의 활성을 저하시킴으로써 암세포 전이에 가장 기본적인 과정인 암세포의 이동성과 침윤성을 억제시킬 수 있을 것으로 생각된다.

• Journal of Microbiology and Biotechnology
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• 제17권11호
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• pp.1856-1861
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• 2007

Physiological cell conditions such as glucose deprivation and hypoxia play roles in the development of drug resistance in solid tumors. These tumor-specific conditions cause decreased expression of DNA topoisomerase $II{\alpha}$, rendering cells resistant to topo II target drugs such as etoposide. Thus, targeting tumor-specific conditions such as a low glucose environment may be a novel strategy in the development of anticancer drugs. On this basis, we established a novel screening program for anticancer agents with preferential cytotoxic activity in cancer cells under glucose-deprived conditions. We recently isolated an active compound, AA-98, from Streptomyces sp. AA030098 that can prevent stress-induced etoposide resistance in vitro. Furthermore, LC-MS and various NMR spectroscopic methods identified AA-98 as mithramycin, which belongs to the aureolic acid group of antitumor compounds. We found that mithramycin prevents the etoposide resistance that is induced by glucose deprivation. The etoposide-chemosensitive action of mithramycin was just dependent on strict low glucose conditions, and resulted in the selective cell death of etoposide-resistant HT-29 human colon cancer cells.

• 약학회지
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• 제53권2호
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• pp.74-77
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• 2009

Food deprivation decreases hepatic glutathione (GSH) levels, which is ascribed to alterations in availability of hepatic cysteine, a rate limiting factor for the GSH synthesis. The present study examines the effects of food deprivation on hepatic metabolism of sulfur amino acid in male rats. In rats fasted for 24 or 48 hours, hepatic GSH levels were decreased from $6.70{\pm}0.16{\mu}mol/g$ liver to $4.02{\pm}0.20$ or $4.06{\pm}0.07{\mu}mol/g$ liver, respectively. Hepatic S-adenosylmethionine levels were also decreased in fasted rats, but S-adenosylhomocysteine levels were increased. Hepatic methionine levels were not changed by food deprivation for 48 hours. On the other hand, hepatic cysteine or taurine levels were increased from $106.2{\pm}4.1$ to $130.0{\pm}2.7$ nmol/g liver or from $2.45{\pm}0.43$ to $5.07{\pm}0.78{\mu}mol/g$ liver, respectively, in 48-hour fasted rats. Activity of cystathionine beta-synthase catalyzed homocysteine to cystathionine, was markedly decreased, but activity of betaine homocysteine methyltransferase was increased in fasted rats, indicating that methylation of homocysteine to methionine is activated. Also activity of cysteine dioxygenase, involved in taurine synthesis, was increased. These results suggested that hepatic methionine levels were maintained in rats fasted for 48 hours through increase in homocysteine methylation, and hepatic GSH may serve as a cysteine supplier reservoir in fasting state.