• 한국의사학회지
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• 제14권2호
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• pp.83-107
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• 2001

"Aheuichaulyo御醫撮要" was known to be published by Choi Jong-jun崔宗峻 in Korea高麗 Dynasty(A.D.1226), however its original copy is not available at the present. It was thought that Korean folk medicine and the remedies were recorded in this book, and these were recorded in "Euibangyoochui醫方類聚" published in Chosun朝鮮 dynasty(1445). "Euibangyoochui" is called a treasure-house of the knowledge of traditional oriental medicine which contains over 50,000 prescriptions and enormous amount of medical information. The restoration of "Aheuichaulyo" was possible during the process of establishment of data base work of "Euibangyoochui". "Aheuichaulyo" was restored as 132 chapters mainly from the related con tents of "Euibangyoochui" and partially from the contents of "Hyangyakjipsungbang鄕藥集成方" and "Boonmoononyukyihaebang分門瘟疫易解方" for the supplement.

• 한국환경보건학회지
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• 제33권3호
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• pp.202-206
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• 2007

Petasites japonicus (Compositae) is a perennial herb which has been used as treatment of antitussive, expectorant, sedatives, paralysis, diurectics in folk remedies. The pharmacological studies of this natural drug have not yet estabilished. So, we examined anti-lipid peroxidative effects and liver protective effect on $CCl_4$ induced lipid peroxidation and hepatotoxicity in rats. In vivo liver lipid, MeOH Ex. revealed significant increase of anti-lipid peroxidative effects according to concentration dependently. In chemical parameters obtained from serum analysis, MeOH Ex. as a increase of medicine concentration (0.25 g/kg, 0.5 g/kg, 1.0 g/kg), GOT, GPT, AlP decreased. In 0.5 g/kg GPT administered group, there was relative in GOT, AlP. Cholesterol decreased in 1.0 g/kg and 1.0 g/kg administered group, BUN decreased relatively in 1.0 g/kg administered group.

• 셀메드
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• 제9권1호
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• pp.4.1-4.2
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• 2019

The aims of this article is to argue that the effect of catharsis through satire and humor in Korean music, Saseolnanongga. This song is a cheerful song of four beats and the representative rap music of Korean traditional music. This song is a folk song that reveals satire and humor such as curse to the person who left me and compassion and self-absorption. The lyrics harmonize with cheerful rhythm and create laughter and the lyrics of the song itself alone cause music therapy. The contents of the lyrics of the song are already refreshing. It means that you will be able to satisfy your surrogacy through the explicit lyrics. In this way, author thinks emotional expression through singing lyrics is an alternative solution. There has been a cathartic element in many twentieth-century approaches to psychological healing. The author thinks developmental criticism leads society to health, and satirical criticism reflects and heals individuals through catharsis.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.121.1-121.1
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• 2003

Houttuynia cordata Thunb (HCT) is a herbal plant growing in China, Japan and Korea. According to the records of the Chinese medicine, this plant has been used as folk medicine for analgesics, beriberi, edema, hepatitis, icterus, etc. TCDD (2, 3, 7, 8 -tetrachlorodibenzo-p-dioxin), one of the notorious toxic environmental pollutants, damages various organs including liver and is regarded as an endocrine disrupter. After 7 days from TCDD (1$\mu$g/kg) injection, HCT (200 mg/kg) was administered into rats intraperitoneally for 4 weeks. (omitted)

• 대한임상독성학회지
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• 제4권2호
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• pp.143-146
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• 2006

Historically, the common folk have made use of various wild herbs for both food and medicinal purposes. However, the misuse of these wild herbs can lead to adverse consequences, including severe poisoning in some cases. In cases of poisoning from wild herbs, patients can exhibit a variety of symptoms depending on the herbs involved, which in addition to gastrointestinal symptoms may include hemodynamic alteration and abnormal neurologic signs. In the present case, two patients were admitted to the emergency room with symptoms of toxicity after consuming Rhododendron brachycarpum liquor. Rhododendron brachycarpum and other wild herbs contain the toxic material grayanotoxin. Because of its serious toxic symptoms, great caution must be exercised in using rhododendrons for food and medicinal purposes.

• 생약학회지
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• 제49권2호
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• pp.138-144
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• 2018

Asparagus oligoclonos is one of the endemic halophytes used folk medicine in Korea. We isolated the main compound rutin from methanol extracts of A. oligoclonos based on nuclear magnetic resonance and TOF ESI-MS data. We have investigated the quantitative analysis method of main compound using HPLC and the results exhibit that rutin content of A.oligoclonos were 1.816%. To explore anti-oxidant from A. oligoclonos ethanol extracts (AOE), we investigated the antioxidant effects of AOE on $H_2O_2$-induced oxidative stress in RAW 264.7 cell. AOE were reduced $H_2O_2$-induced oxidative stress via enhancement of cell viability, and AOE significantly decreased ROS production depending on concentration. Next, to screen for anti-inflammatory activity of AOE, we investigated the inhibitory effects of AOE in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. AOE had no effect on cell viability at a concentration of $500{\mu}g/mL$. Nitric oxide (NO) production inhibited in a dose-dependent manner. These results suggest that AOE may be a useful antioxidant and anti-inflammatory agent.

• 대한한의학회지
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• 제27권1호
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• pp.78-90
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• 2006

Background : Traditional herbal medicine is used extensively among the Korean populations, and other Asian countries employ similar therapies as well. In recent years, extensive focus was laid on adulteration of the herbal medicine with liver damage. The use of herbal preparations as remedies for various medical conditions has continuously increased in Korea. Large proportions of Korean patients use herbal medicinal products, folk remedies, and health food. However, studies on the safety of herbal products are conducted on a less than sufficient basis even in the countries like Korea where herbal medicine is being used extensively. Some of the reports on the safety of herbs were done by the doctors of western medicine but lack of knowledge and misclassification led to misunderstandings. Objectives : This study aims to verify the evidences on safety of frequently used 4 herbal medications (Sipjeondaebo-tang, Bojungikgi-tang, Ohjeok-San, Yukmaijihwang-tang) in the lab animal model. Methods : Sprague-Dawley rats was treated by 4 herbal medications during 31 days. After 1 month, we checked body weight, liver weight, and serum enzyme associated with liver function. Results : There is no significant difference in body weight and liver weight after 1 month of administrations. In all experimental groups, no abnormal findings was observed in histotogical research and lab liver Functions test(AST, ALT etc). Conclusions : These four herbal medications, frequently used in oriental medicine clinics and hospitals, are safe from hepatoxic events in the lab animal model.

• Natural Product Sciences
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• 제20권3호
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• pp.196-201
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• 2014

Pyunkang-hwan (Pyunkang-tang) extract (PGT) is a traditional folk medicine for controlling diverse pulmonary diseases including bronchitis, tonsiltis and pneumonitis. We investigated whether PGT significantly affects secretion, production and gene expression of airway mucin using in vivo and in vitro experimental models reflecting the hypersecretion and/or hyperproduction of mucus observed in inflammatory pulmonary diseases. For in vivo experiment, effect of PGT was checked on hypersecretion of pulmonary mucin in sulfur dioxide-induced bronchitis in rats. For in vitro experiment, confluent NCI-H292 cells were pretreated with PGT for 30 min and then stimulated with EGF (epidermal growth factor), PMA (phorbol 12-myristate 13-acetate) or TNF-${\alpha}$ (tumor necrosis factor-${\alpha}$) for 24 h. The MUC5AC mucin gene expression and mucin protein production were measured by RT-PCR and ELISA. The results were as follows: (1) PGT inhibited the expression of MUC5AC mucin gene induced by EGF, PMA or TNF-${\alpha}$ from NCI-H292 cells, respectively; (2) PGT also inhibited the production of MUC5AC mucin protein induced by the same inducers from NCI-H292 cells, respectively; (3) PGT inhibited secretion of mucin in sulfur dioxide-induced bronchitis rat model. This result suggests that PGT can regulate secretion, production and gene expression of airway mucin.

• Korean Journal of Acupuncture
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• 제28권4호
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• pp.137-145
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• 2011

Objectives : This research dealt with the content of the hot medicinal compress technique in Donguibogam in order to develope the hot medicinal compress technique as a new therapy technique. Methods : In this research, we searched for the hot medicinal compress treatment in Donguibogam. Results : The hot medicinal compress technique mainly cures the diseases on the body surface and it can be applied to digestive troubles and gynecologic diseases. The hot medicinal compress technique is operated mainly at wound around the affected parts and it is applied to the constitutional symptom at the abdominal region. In the hot medicinal compress technique was used much more with medication, and the herbs used in the treatment consists of hot tastes and the warm characteristics. In the hot medicinal compress method with direct heating the herbs was mainly used. Conclusions : The hot medicinal compress technique is considered as treatment which can be utilized easily and it can be used an easy and useful self-treatment.

• 한방안이비인후피부과학회지
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• 제33권1호
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• pp.83-88
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• 2020

Objectives : In traditional Korean medicine literature, Succium(琥珀) is known to be effective in eliminating edema. However, pumpkins are misused in folk remedies to manage edema, because succium and pumpkin is homophony to 'Hobak' in Korean. The purpose of this study is to report the effects of Succium decoction on two patients with edema after plastic surgery. Methods : We treated two patients with edema after plastic surgery using Succium decoction. Numeric rating scale (NRS) of edema, photograph of changes in edema before and after treatment were analyzed to evaluate the effects of treatment. Results : After 2 weeks of administration, NRS for facial edema decreased from 5 to 3 and 2 to 1, respectively. Photograph of edema decreased after treatment, and there were no adverse events. Conclusions : This case report suggests that Succium decoction can be effective in treating edema after plastic surgery.