• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.105-105
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• 2002

A wide range of chemicals derived from plant and human-made xenobiotics are reported to have hormonal activity. The present studies were performed to examine the estrogenic effect of Kwao Keur, Pueraria mirifica (PM), that has been used a rejuvenating folk medicine from Thailand, using recombinant yeast, MCF-7 cell proliferation and HepG2 cell transient transfection assay.(omitted)

• Journal of Applied Biological Chemistry
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• v.60 no.4
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• pp.373-381
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• 2017

Hippocampus abdominalis, the big belly sea horse, is widely known for its medicinal value in Chinese folk medicine. In this study, extract obtained by proteolytic degradation of this species was investigated for its effects on skeletal muscle development, both in vitro and in vivo. Muscle cell lines ($C_2C_{12}$ and $L_6$) treated with the bioactive peptide did not have any detrimental effects on the cell viability, which was above 80%. Optical microscopy analysis on the morphology of the sea horse extract (SHE)-treated cells showed enhanced differentiating ability with myotube formation. Moreover, cells incubated with the hydrolysate displayed decreased proliferation rate, as recorded by the electric cell substrate impedance sensing system, thereby supporting enhanced differentiation. For a period of 12 weeks, mice models were fed with SHE and simultaneously subjected to treadmill exercise, which increased the expression of Myogenin, a key myogenic regulatory factor. In addition, there was an increase in the expression of AMPK- and Cytochrome C, both of which are important in mitochondrial biogenesis. Thus, the SHE from Hippocampus abdominalis can be a promising candidate as protein supplement aiding muscle development.

• The Journal of Korean Medical History
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• v.33 no.1
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• pp.59-78
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• 2020

The Summary Handbook of Acupuncture and Moxibustion (鍼灸要覽) (SHAM) was written by an unknown folk healer who learned acupuncture about 100 years ago in Korea. The book discusses 79 acupoints and includes a table of contents, a text, and a pair of acupoint charts. The acupoints in the book are classed under two headings, 49 acupoints of 14 meridians and 33 acupoints. A number of the acupoints such as Gichoong (氣忠), Eumheobong (陰虛峰), Goowa (口卧), Cheonryang (天良) did not fit the then existing meridian system and were newly uncovered by the authors. The book also discusses needle insertion depth in a way that is quite different from how insertion depth is understood by clinicians today. Books such as SHAM that record new acupoints and treatments are rare among Korea's existing medical and clinical books and can be said to be very important in terms of medical history.

• The Korean Journal of Physiology
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• v.26 no.1
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• pp.37-44
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• 1992

The encapsulation of the Purified bovine hemoglobin with Phospholipids obtained from egg folk was performed using a rotary vacuum evaporator. The prepared Hb-containing liposome (hemosome) had good properties as artificial red blood cell. The shape and size of the hemosomes were measured by a phase contrast microscope and image analyzer. The function of the hemosome as oxygen carrier was tested by measuring oxygen saturation curve with blood gas analyzer and infusing it into rats. The prepared hemosome was 1.184 + 0.423 ${\mu}m$ in diameter and round in shape. $P_{50}$ value of the hemosome solution was 28 mmHg. The synthesized red cells seem to function as oxygen carrier, because the severely bled rats were prolonged in their life by transfusion of the hemosome solution containing bovine hemoglobin.

• CELLMED
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• v.6 no.2
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• pp.8.1-8.2
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• 2016

The purpose of this article is to argue that Arirang, Korean traditional music, could be used for healing purposes for Koreans. Music may be a medicine for curing both the body and mind. That is the soul of folksong. Arirang is a representative folksong in Korea. Koreans thought that listening to Korean traditional songs and singing them have healing powers because it makes people happier. When Koreans listen to Arirang, slowly as if they are mass hypnotized, Koreans calmed down because they think of mother's bosom while listening to Arirang. Also, Koreans find comfort in listening and singing to Arirang. The song's tune is catchy and its lyrics are moving. The song of Arirang was sung from long ago by Koreans. Therefore, it will continue forever as long as Koreans exist.

• Journal of Society of Preventive Korean Medicine
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• v.12 no.2
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• pp.145-157
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• 2008

There were many books on infectious disease prevention act, and still remained 5 books including Ganuibyeokonbang. Epidemics were seriously ill and widely contagious, so it was important to prevent them. Therefore, they wrote various preventive measures from epidemics on those books. They emphasized medication, and used not only compound prescriptions but also singular ones. They wrote 5 compound prescriptions including Sohaphyangwon and many singular ones on Ganuibyeokonbang, and they used folk medicine such as red-beans준 for practical use on that book. On Sinchanbyeokonbang, they emphasized Hyangsosan and presented many prescriptions to specialize in epidemics. Heojun presented various prescriptions for Dangdokyeok on Byeokyeoksinbang, and he excluded incantation methods to cope with epidemics medically. Since Ganuibyeokonbang they had tried to improve personal hygiene such as boiling clothes of patients.

• Journal of Korean Medical classics
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• v.36 no.1
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• pp.33-43
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• 2023

Objectives : Overlapping contents between two recently discovered Han period bamboo slats, the so-called "Beidahanjian" and the "Liushibingfang" have been identified. This study aims to present new knowledge that could be inferred from the concordance of these two texts. Methods : The most recent original texts of the medical part of the Beidahanjian and medical texts excavated from the Laoguanshan in addition to the Liushibingfang were compared with each other to determine identical parts. The meaning of these concordances was explored. Results : Identical sentences in two verses in the Beidahanjian and the Laoguanshan were identified. Conclusions : The Beidahanjian is a credible Western Han period text, of which the medical bamboo slats are likely to comprise an independent text that is a combination of ancient folk prescriptions and those of doctors.

• Biomedical Science Letters
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• v.29 no.1
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• pp.26-33
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• 2023

Ziziphus jujuba Mill. (ZJM), a traditional folk medicine and functional food in South Korea and China, has been reported to having pharmacological activities against anti-cancer, anti-oxidative, and anti-obesity. However, the effect of ZJM related to myoblast differentiation has not been known. In this study, we investigated the effects and mechanism of ZJM on myogenic differentiation of C2C12 cells. ZJM promotes myogenic differentiation and elevates the formation of multinucleated myotube compared to the control group. ZJM significantly increased the mRNA and protein expression of MyHC1, myogenin and MyoD in dose- and time-dependent manner. Interestingly, ZJM significantly inhibited the mRNA and protein expression of protein degradation markers, atrogin-1 and MuRF-1, in dose- and time-dependent manner. Taken together, our data suggest that ZJM is a potential functional candidate for muscle growth and strength by promoting myogenic differentiation.

• Korean Journal of Pharmacognosy
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• v.38 no.3 s.150
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• pp.254-257
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• 2007

The aerial parts of Brassica juncea (Cruciferae) called by brown or oriental mustard have been widely used as a spice in food and also traditional folk medicine as stimulant, diuretic and expectorant agent. And Gatkimchi made of the aerial parts of this plant are very popular in Korea. The aerial parts of this plant was refluxed with MeOH and then fractionationed with $CH_2Cl_2$, EtOAc, n-BuOH and $H_2O$, successively. One higher alcohol compound and three flavonoids were isolated from the EtOAc fraction through silica gel and Sephadex LH-20 column chromatographies. Their structures were elucidated as n-hexacosanol(1), kaempferol(2), isorhamnetin $3-O-{\beta}-D-glucopyranoside(3)$ and isorhamnetin $3-O-(6'-O-acetyl)-{\beta}-D-glucopyranoside(4)$ by comparison of spectral data with those in references. And compounds 1 and 4 were firstly isolated from this plant.

• Advances in Traditional Medicine
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• v.7 no.3
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• pp.217-228
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• 2007

Agrimonia pilosa Ledeb. has long been used for a useful natural agent ameliorating inflammation related symptoms in the folk medicine recipe. This study was performed to investigate effects of Agrimonia pilosa Ledeb.(AP) on the expression of inflammation related genes such as the inducible nitric oxide synthase (iNOS) in macrophage cell line, RAW 264.7 cells. The AP (whole plants) was extracted with 80% ethanol and sequentially partitioned with solvents in order to increase polarity. Among the various solvent extracts of AP, the n-butanol (BuOH) fraction showed the most powerful inhibitory ability against nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 cells without affecting cell viability. Reverse transcriptase-polymerase chain reaction and Western blot analysis revealed that the BuOH fraction provided a primary inhibitor of the iNOS protein and mRNA expression in LPS-induced RAW 264.7 cells. The DPPH and OH radical scavenging activities of the several fractions of 80% ethanol extracts of AP significantly increased by EtOAC and BuOH fractions. Thus, the present study suggests that the response of a component of the BuOH fraction to NO generation via iNOS expression provide an important clue to elucidate anti-inflammatory mechanism of AP.