• 제목/요약/키워드: Foam cell

검색결과 258건 처리시간 0.029초

시호 추출물의 oxLDL 유도 Foam Cell 형성 억제 작용 (Inhibitory Effects of Bupleuri Radix on ox-LDL induced Foam Cell Formation)

  • 이혜진;배호성;황귀서
    • 대한예방한의학회지
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    • 제16권2호
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    • pp.113-124
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    • 2012
  • The oxidative modification of low density lipoprotein(LDL) has been implicated in the development of atherosclerosis. Oxidized LDL(oxLDL) is captured into macrophage and stimulates to form macrophage foam cell. And it can induce an inflammation and smooth muscle proliferation in atherosclerotic plaque. Objective : In this study, we aimed to investigate the effect of Bupleuri radix(SH) on the foam cell formation, a critical initiation stage of atherosclerosis. Methods : To achieve the goal, we examined the effect of SH on LDL oxidation, nitric oxide production in RAW264.7, and the effect of SH on cupuric sulfate-induced cytotoxicity, LDH release, and macrophage activity. Results : SH inhibited the formation of oxidized LDL from native LDL in RAW264.7 cell culture, and decreased the release of LDH from cupric sulfate-stimulated RAW264.7 cell. In other experiments, SH activated RAW264.7 cell, and prolonged the survival time, and inhibited foam cell formation induced by oxLDL in Raw 264.7 cells. Conclusion : These results showed that SH might prevent atherosclerosis by controlling the early stages of foam cell formation.

고탄성 폴리우레탄 발포체의 기포개방 I. 폴리에테르형 기포개방제의 농도 영향 (Cell Opening of High Resilience Polyurethane Foam I. Concentration Effect of Polyether Type Cell Opener)

  • 송기천;이상목;이동호
    • 폴리머
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    • 제25권5호
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    • pp.679-690
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    • 2001
  • 폴리에테르형 기포개방제를 사용한 고탄성 폴리우레탄 발포체의 제조에서 기포개방제의 농도변화가 계의 반응속도, 유변학적 성질, 발포체의 구조적인 안정성, 형태학적 성질 및 개방기포의 함량 등에 미치는 영향을 조사하고 이를 통하여 기포개방에서 기포개방제의 역할을 알아보았다. 또한 기포개방제의 농도에 따른 발포체의 기계적 물성을 관찰하였다. 기포개방제의 높은 친수성으로 인해 우레아 생성반응이 지연됨을 관찰하였다. 유변학적 성질의 관찰을 통하여 기고개방제의 농도 증가에 따라 계의 점도저하와 tan $\delta$의 증가를 확인하였고 이로 인해 얻어진 발포체는 낮은 구조적인 안정성과 높은 개방기포 함량을 나타내었다. 기포개방제의 농도 증가에 따라 matrix의 파괴와 matrix내 수소결합된 우레아의 고른 분산을 발포체의 형태학적 성질의 관찰로 확인할 수 있었다. 결론적으로 고탄성 폴리우레탄 발포체의 제조시 기포개방제의 높은 친수성에 기인하여 matrix의 탄성특성 저하가 일어나고 이로 인해 높은 개랑기포 함량을 가진 발포체가 형성됨을 알 수 있었다. 발포체의 경도, 인장강도, 인열강도, 신율 등은 기포개방제의 농도 증가에 따라 저하하였다.

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알루미늄 발포금속의 유효열전도도와 침투율의 측정 (Measurement of effective thermal conductivity and permeability on aluminum foam metal)

  • 백진욱;강병하;김서영;현재민
    • 설비공학논문집
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    • 제11권2호
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    • pp.185-192
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    • 1999
  • Effective thermal conductivities and pressure-drop-related properties of aluminum foam metals have been measured. The effects of porosity and cell size in the aluminum foam metal are investigated in detail. The porosity of the foam metal, considered in the present study, varies from 0.89 to 0.96 and the cell size from 0.65㎜ to 2.5㎜. The effective thermal conductivity is evaluated by comparing the temperature gradient of the foam metal with that of the thermal conductivity-known material. The pressure drop in the foam metal is measured by a highly precise electric manometer while air is flowing through the aluminum foam metal in the channel. The results obtained indicate that the effective thermal conductivities are found to be increased with a decrease in the porosity while the effective thermal conductivities ire little affected by the cell size at a fixed porosity. However, the pressure drop is strongly affected by the cell size as well as the porosity. It is seen that the pressure drop is increased as the cell size becomes smaller, as expected. The minimum pressure drop is obtained in the porosity 0.94 at a fixed cell size. A new correlation of the pressure drop is proposed based on the permeability and Ergun's coefficient for the aluminum foam metal.

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실리콘 정포제의 종류에 따른 폴리우레탄 폼 지수제의 내수성 특성에 관한 연구 (Studies on the Water Resistance Properties of the Polyurethane Foam Silicone Foal Control Agent according to the Type of Silicone Foam Stabilizer)

  • 김근허;김현민;김성래;김영근
    • 한국구조물진단유지관리공학회 논문집
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    • 제20권2호
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    • pp.60-66
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    • 2016
  • 본 연구는 실리콘계 정포제의 특성에 따른 폴리우레탄 폼 지수제의 cell 구조와 흡수량 변화를 알아보기 위하여 6종의 정포제를 사용하여 폴리우레탄 폼 지수제를 제조하여 FE-SEM으로 분석한 결과 실리콘 정포제의 실록산 주사슬 말단에 PO n개가 결합되어 있는 DC-193, DC-2585, DC-5125, DC-198의 cell 구조는 close cell로 확인이 되었고, 실리콘 정포제의 실록산 주사슬 말단에 EO n개가 결합 되어 있는 DC-5043과 DC-5598은 open cell 구조로 나타났다. 또한 cell 구조 변화에 따른 흡수량 에서는 close cell의 크기가 가장 세밀하고 균일한 DC-193의 흡수량이 가장 적게 나타나 내수성이 가장 우수한 것으로 나타났으며 open cell의 크기가 가장 크게 형성된 DC-5043의 흡수량이 가장 많은 것으로 나타났다. 이들의 방수성능을 콘크리트 구조물을 모사하여 시험한 결과 누수가 없음을 확인하였다.

액화질소를 이용한 오픈 셀 실리콘 폼의 냉동 절삭조건 최적화 (Cryogenic Machining of Open-Cell Silicone Foam)

  • 황지홍;조광희;박민수
    • 한국생산제조학회지
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    • 제23권1호
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    • pp.32-37
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    • 2014
  • Open-cell silicon foam is difficult to cut using conventional machining processes because of its low stiffness. That is, open-cell silicon foam is easily pressed down when the tool is engaged, which makes it difficult to remove the material in the form of chip. This study proposes an advanced method of machining open-cell silicon foam by freezing the material using liquid nitrogen. Furthermore, the machining conditions are optimized to maximize the efficiency of material removal and minimize the usage of liquid nitrogen by conducting experiments under various machining conditions. The results show that open-cell silicone foam products with free surface can be successfully machined by employing the proposed method.

Metal foam을 사용한 고분자 전해질 연료전지 성능 연구 (A Study on Performance of Polymer Electrolyte Membrane Fuel Cell Using Metal Foam)

  • 김묘은;김창수;손영준
    • 한국수소및신에너지학회논문집
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    • 제26권6호
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    • pp.554-559
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    • 2015
  • Single cell of PEMFC (polymer electrolyte membrane fuel cell) is composed of bipolar plates, gasket, GDL and the MEA. Bipolar plate's function is the collecting electricity, helping oxygen/hydrogen gas diffuse evenly and draining the water and heat. In this work, we have conducted experiments to low contact resistance and improve the performance of a $25cm^2$ single cell by using metal forms. We have following experimental cases: 1) Conventional graphite serpentine channel bipolar plate; 2) Channel-less bipolar plate with nickel(Ni) based metal foam which coated by various materials. We focused the difference in contact resistance and performance of the single cell with metal foam depending on various coating materials. The experimental results show the similar performance of single cells between with serpentine channel bipolar plates and with channel-less bipolar plate using metal foams. In addition, single cell with metal foam shows potential to higher performance than conventional channel.

판이 부착된 개포형 발포 알루미늄의 인장특성 (Tensile Properties of Plate Attached Open Cell Aluminium Foams)

  • 강복현;부성덕;김기영
    • 한국주조공학회지
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    • 제27권2호
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    • pp.83-87
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    • 2007
  • Aluminum plates of the same materials as the foam were attached by the casting process inserting the foam as a core to investigate the tensile property of open cell foams. Tensile properties of the open cell 6063 aluminum alloy foam of $10{\sim}30$ PPI were measured before and after heat treatment. Densities of test specimens were between 0.14 and $0.29g/cm^3$. Tensile strength of the 6063 aluminum foam after heat treatment showed little change. C values were in the range of $0.41{\sim}0.87$ for as cast foams and $0.11{\sim}0.27$ for T6 heat treated foams in the eq. of ${\sigma}^* _{pl}/{\sigma}_{ys}=C({\rho}/{\rho}_s)^{1.5}$, and increased with increase in the cell size.

나노인덴테이션에 의한 Al-Si-Cu-Mg 합금 폼 셀 벽의 기계적 물성 연구 (A Nanoindentation Based Study of Mechanical Properties of Al-Si-Cu-Mg Alloy Foam Cell Wall)

  • 하산;김엄기;이창훈;이학주;고순규;조성석
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 춘계학술대회
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    • pp.382-387
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    • 2004
  • Nanoindentation technique has been used to measure the mechanical properties of aluminium alloy foam cell walls. Al-Si-Cu-Mg alloy foams of different compositions and different cell morphologies were produced using powder metallurgical method. Cell morphology of the foam was controlled during production by varying foaming time and temperature. Mechanical properties such as hardness and Young's modulus were calculated using two different methods: a continuous stiffness measurement (CSM) and an unloading stiffness measurement (USM) method. Experimental results showed that hardness and Young's modulus of Al-5%(wt.)Si-4%Cu-4%Mg (544 alloy) precursor and foam walls are higher than those of Al-3%Si-2%Cu-2%Mg (322 alloy) precursor and foam walls. It was noticed that mechanical properties of cell wall are different from those of precursor materials.

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보로노이 셀을 이용한 2 원 비등방성 폼 구조 모델링 및 탄소성 압축변형 해석 (Modeling of the Elasto-plastic Deformation Behavior of Two-Dimensional Anisotropic Foam under Compressive Loads using Voronoi Cells)

  • 한원희;최병호;김일현;이정무
    • 한국정밀공학회지
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    • 제29권7호
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    • pp.785-792
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    • 2012
  • Foam structure is usually hard to model due to the complexity of the geometry of cells. So, many simplified models to represent complicated foam structures have been proposed, but most of them are not actually describe the random feature of the cell structure well. So, in this study, two dimensional isotropic and anisotropic closed cell structures of the foam were modeled using the concept of Voronoi cells. The elasto-plastic deformation behavior under compressive loads was investigated by finitie element analysis, and the results were compared with ideal honeycomb structure. In addition, the effect of anisotropy of Voronoi cell structures of the foam on Young's modulus and yield stress under compressive loads was studied.

폴리우레탄 폼을 이용한 친유성 유체의 흡착 (Adsorption of Hydrophobic Fluid by Polyurethane Foam)

  • 채주병;김병규;신영조
    • 공업화학
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    • 제9권5호
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    • pp.648-653
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    • 1998
  • 본 연구에서는 폴리우레탄 폼의 셀 내부구조 및 크기가 친유성 유체의 흡유능에 미치는 영향을 체계적으로 연구하였다. 우선 다양한 분자량의 폴리올 (GP-1000, GP-3000, GP-4000, GP-5000)을 이용하여 폴리우레탄 폼을 제조하여 그 기본적인 물성을 조사하였다. 폴리올의 분자량이 증가함에 따라 셀 크기가 감소하고 흡유량이 2000% 이상 증가하였다. Surfactant량이 증가하고 흡착되는 유체의 점도가 증가함에 따라 흡유량이 현저하게 감소함을 알 수가 있었다. 또한 폴리올의 분자량이 증가함에 따라 표면강도가 상승하였는데 이는 분자량 증가에 따른 유체점도의 상승이 폼밀도를 증대시킨데 기인한 것으로 해석할 수 있었다. 폼생성시 교반속도가 증가하여도 밀도가 증가하였다.

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