• The Korean Journal of Physiology and Pharmacology
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• v.2 no.5
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• pp.573-580
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• 1998

The study aims to identify the mechanism (s) underlying the altered vasodilatory responses of the pial artery of spontaneously hypertensive rats (SHR) under a hypothesis that calcitonin gene-related peptide (CGRP) exerts a modulator role in the autoregulation of cerebral blood flow (CBF). The animals were divided into four groups: 1) Sprague-Dawley rats (SDR), 2) Wistar rats (WR), 3) SHR with high blood pressure $(BP{\ge}150\;mmHg),$ and 4) SHR with normotensive BP $({\le}150\;mmHg).$ The lower limit of CBF autoregulation in SHR shifted to a higher BP $(82.8{\pm}9.3\'mmHg,\;P<0.05)$ than that in SDR $(58.9{\pm}5.7\;mmHg)$. In SHR, whether the BP levels were high or normotensive, the vasodilator responses to a stepwise hypotension were significantly attenuated unlike with SDR and WR. When artificial cerebrospinal fluid (CSF) containing capsaicin $(3{\times}10^{-7}\;M)$ was suffused over the cortical surface, a transient increase in pial arterial diameter was observed in the SHR with high or normotensive BP. In contrast, SDR and WR showed a large increase in diameter, and the increase was sustained for over 10 minutes. In line with these results, the basal releases of CGRP-like immunoreactivity (CGRP-LI) in the isolated pial arteries from SHR with high and normotensive BP were $12.5{\pm}1.4\;and\;9.8{\pm}2.8\;fmole/mm^2/60\;min\;(P<0.05)$, while those from SDR and WR were $25.5{\pm}3.1\;and\;24.6{\pm}3.1\;fmole/mm^2/60\;min,$ respectively. The isolated basilar arteries showed similar results to those of the pial arteries in SHR. Thus, it is summarized that, in the SHR, the reduced autoregulatory vasodilator responses to stepwise hypotension and capsaicin may be, in part, ascribed to the decreased release of CGRP from the perivascular sensory nerve fibers of the pial arteries, and that altered vasomotor activity in SHR may not be related with the hypertensive tone.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.15 no.1
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• pp.52-60
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• 2005

This study was carried to assess the accuracy of material safety data sheets (MSDS) for some water-soluble metalworking fluid (MWF) with respect to mono- ethanolamine(MEA), di-ethanolamine(DEA) and tri-ethanolamine (TEA). 39 fresh and 52 used MWFs for this study were taken from the workplace. The quantification and qualification of MEA, DEA and TEA were done using ion-chromatography. Three main findings of this study were 1) EA that was not addressed in material safety & data sheets (MSDS) was found to be enough higher than 1%, 2) 33.3% of 39 fresh MWF showed ingredient and concentration of MEA, DEA and TEA in MSDS and 3) the concentrations of MEA(20.5%), DEA(41.3%) and TEA(15.4%) were much higher than those indicated in MSDS. Consequently, we concluded that the accuracy on ingredients and concentrations of MEA, DEA and TEA provided in MWF was very low. Our study recommends that the limit concentration of chemical except for carcinogen that employer has to indicate in MSDS should be lowered from 1% to 0.1% .

• Journal of Drive and Control
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• v.16 no.4
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• pp.16-22
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• 2019

The electro-hydraulic training device (TP511) provided by Festo Didactic are widely used, but teaching materials do not include mathematical modeling. Thus, there is a limit for full-scale learning about the electro-hydraulic servo system by using this equipment. In this study, for the purpose of improving students' understanding of the classical control and modern control Festo's electro-hydraulic servo training device (TP511) was mathematically modeled and parameter values were calculated by examining the characteristics of each component. And P, PI, PD, and PID controllers highly used in the industrial field, were designed by using the root locus method to achieve the optimal gains and used for simulation and experiments using the Festo's electro-hydraulic servo training apparatus. The validity of the derived mathematical model and the calculated parameter values were verified through simulation and experiment. It was found that the p control can achieve the control target more effectively than the pid control for Festo's electro-hydraulic servo training system by using the root locus method.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.47 no.5
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• pp.229-234
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• 2010

This paper proposed the acoustic signal processing techniques, which are applicable even in the shallow river, and will enhance the frequency resolution of the ADCP (Acoustic Doppler Current profiler). ADCP is a device that measures the velocity of a moving fluid. ADCP, in general, can be operated at ~300 Khz of center frequency due to no depth limit in the sea. However, it can hardly be used due to water depth of 30cm or shallower during the dry season in the river. Therefore, existing signal processing methods are not suitable to use in the shallow river. We are proposing an alternative acoustic signal processing method using Zoom FFT. Simulation results show that errors are reduced ${\pm}62\;cm/s$ in theory, and ${\pm}93\;cm/s$ in the experiment. The existing algorithm could not estimate the current speed at the shallow river below 30 cm, but proposed algorithm estimated the current speed that was faster than 20 cm/s at the shallow river below 30 cm.

• 모자간호학회지
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• v.2 no.1
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• pp.55-69
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• 1992

This study was planned and carried out 1) to identify the general menstrual characteristics, 2) to understand perimenstrual discomfort, menstrual attitude, and sex role acceptance, 3) to investigate the correlation between perimenstrual discomfort, menstrual attitude, sex role acceptance in order to provide basic information about menstruation. The subjects of this study were 313 college women and they were asked to check Menstrual Discomfort questionnaire, Menstrual Attitude Questionnaire, and Role Acceptance Scale. Data were gathered from April 1 to June 24, 1992. The results were as follows : 1) The mean age of the subjects was 19, and the mean age of monarch was 13.6 ranged from 11 to 19. The distribution of menstrual cycle showed a wide variation and the mean cycle was 29.7 days. The duration of menstrual cycle was between 2-8 days, and in 65.8% the amount of menstrual fluid was within normal limit. 2) The frequencies of perimenstrual discomfort was 56.9% when asked to check it on 5 point scale. 3) All scores of perimenstrual discomfort were higher on premenstrual period than intermenstrual period, and higher on menstrual period than premenstrual period. They were statistically significant. 4) In general, the college women perceived menstruation as natural, somewhat bothersome, and not very debilitating or predictable, although they did not deny that menstruation had some effects. 5) The correlation between perimenstrual discomfort and menstrual attitude was significant. 6) The correlation between perimenstrual discomfort and sex role acceptance was significant. 7) The correlation between menstrual attitude and sex role acceptance was significant.

• Journal of Biosystems Engineering
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• v.32 no.6
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• pp.440-447
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• 2007

In this study, a biosensor was developed using an enzyme-linked immunosorbent assay (ELISA) to rapidly measure the fungicide iprovalicarb residues in agricultural products. The biosensor was designed to include micro-pumps and solenoid valves for fluid transport, a spectrophotometer cuvet as a reaction chamber, a photodiode with a light-emitting diode for optical density measurement, and a control microcomputer to implement assay. The rate of change in optical density of the cuvet was read as final signal output. Micro-pumps were evaluated to investigate their delivery capability, the highest values of the error and the coefficient of variation were 4.3% and 4.6% respectively. As the incubation period was reduced from 15 minutes to 11 minutes to shorten the total processing time, the sensor sensitivity was decreased as the antibody dilution ratio was reduced to a half. The maximum usable period of the coated cuvet was found to be two days with 1% error limit. To predict the concentration of the iprovalicarb residue in agricultural products, a linear calibration model was obtained with r-square values of 0.992 for potato and 0.985 for onion. In validation test for the samples of potatoes and onions against the high performance liquid chromatography, very high correlation values were obtained as 0.996 and 0.993 respectively. Using the cuvet immobilized with antigen, it took 21-minutes for the biosensor to complete the measuring process of the iprovalicarb residues.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.15 no.3
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• pp.270-276
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• 2005

This study was conducted to examine whether a specific synthetic metalworking fluid (MWF), "A", in use for 10 months without replacement, displayed microbial resistance and to identify the additives associated with the control of microbial growth. Three synthetic MWF products ("A", "B", and "C") were studied every week for two months. Microbial deterioration of the fluids was assessed through evaluation by endotoxin, bacteria and fungi levels in the MWFs. In addition, formaldehyde, boron, ethanolamine, and copper levels were also studied to determine whether they influence microbial growth in water-based MWFs. Throughout the entire study in the sump where MWF "A" was used, bacteria counts were lower than 103 CFU/mL, and endotoxins never exceeded 103 EU/mL. These levels were significantly lower than levels observed in sumps badly deteriorated with microbes. Boron levels in MWF "A" ranged from 91.7 to 129.6 ppm, which was significantly higher than boron levels found in other MWF products. The total level of ethanolamine (EA) in MWF "A" ranged from 35,595 to 57,857 ppm (average 40,903 ppm), which was over ten times higher than that found in other MWFs. Monoethanolamine (MEA), diethanolamine (DEA) and triethanolamine (TEA) concentrations in MWF "A" were also significantly higher than seen in other MWFs. However, although EA and boron might improve anti-microbial performance, their abuse can pose a serious risk to workers who handle MWFs. From an industrial hygiene perspective, our study results stress that the positive synergistic effect of boron and EA in reducing microbial activity in MWF must be balanced with the potentially negative health effects of such additives. Our study also addresses the disadvantage of failing to comprehensively report MWF additives on Material Safety Data Sheets (MSDS). Future research in MWF formulation is needed to find the best level of EA and boron for achieving optimal synergistic anti-microbial effects while minimizing employee health hazards.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.5
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• pp.553-561
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• 2010

A medium-scale helium loop that can simulate a VHTR (very-high-temperature reactor) is now under construction at the Korea Atomic Energy Research Institute. The heaters of the test helium loop electrically heat helium fluid up to $950^{\circ}C$ at pressures of 1 to 9 MPa. To optimize the design specifications of the experimental helium loop, the conjugate heat transfer in the high-temperature helium heater was analyzed by performing a CFD simulation. The analysis results indicate that the maximum temperature does not exceed the allowable limit. It is confirmed that the thermal characteristics of the loop with the given geometry satisfy the design requirements.

• Journal of Food Hygiene and Safety
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• v.4 no.1
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• pp.21-27
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• 1989

This study was performed to investigate the mercury concentration of restaurant meals and to estimate the total dietary intake of mercury. Experimental subjects were 66 cases in 11 kinds of common restaurant meals collected from the Seoul area. Total mercury was determined by Hg-analyzer and two kinds of atomic absorption spectrophotometer (AAS). The results were as follows: 1. Mean value of mercury contents in fluid of meals was about 0.002 ppm and there was no significant difference between the two methods. 2. Mercury concentration of residue by AAS was significantly higher than that by Hg-analyzer. The mean values of mercury concentration were 2.423 ppm, 10.229 ppm and 11.655 ppm by Hg-analyzer, AAS-PE and AAS-Hi, respectively. 3. Dietary intake of mercury from the meals was estimated $7.806\;\mu\textrm{g}/day$ by Hg-analyzer and 31.290, $35.349\;\mu\textrm{g}/day$ by two kinds of AAS. The values were lower than the FAO/WHO limit, $42.9\;\mu\textrm{g}/day$.

• Nuclear Engineering and Technology
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• v.27 no.1
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• pp.45-52
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• 1995

In influence of the vapor phase turbulent stress (i.e., the too-phase Reynolds stress) to the characteristics of two-phase system in a horizontal pipe has been theoretically investigated. The average two-fluid model has been constituted with closure relations for stratified flow in a horizontal pipe. A vapor phase turbulent stress model for the regular interface geometry has been included. It is found that the second order waves propagate in opposite direction with almost the same speed in the moving frame of reference of the liquid phase velocity. Using the well-posedness limit of the two-phase system, the dispersed-stratified How regime boundary has been modeled. Two-phase Froude number has been found to be a convenient parameter in quantifying the onset of slugging as a function of the global void fraction. The influence of the taper phase turbulent stress was found to stabilize the flow stratification.