• Journal of Advanced Marine Engineering and Technology
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• 제34권1호
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• pp.177-182
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• 2010

인공어초의 구조적 설치로 인하여 흐름의 변화가 생기며, 이로 인한 인공어초 주변의 퇴적물 수송은 침전과 매몰뿐만 아니라 저질 환경에도 영향을 미친다. 본 조사는 경상북도 포항시 해역에 시설된 사각형 어초의 시설상태를 파악하기 위하여 수중음향 영상기기인 사이드 스캔 소나(SSS), 인공위성 위치 측정기(DGPS)와 잠수조사를 통한 조사를 실시하였다. 조사 결과, 총 139개소에서 10,526개의 사각형 어초가 발견되었으며, 어초 기능 유지에 영향을 미치는 수준으로 판단되는 0.5m 이상의 매몰과 세굴은 각각 4개소(0.5~1.2m, 2.9%)와 3개소(0.5m, 2.2%)로 나타났다. 파손의 경우 10,526개의 발견된 사각형 어초 중 183개(1.74%)로 나타났다. 따라서 포항시 해역에 시설된 사각형 인공어초의 시설상태는 비교적 안정적인 것으로 나타났다.

• Journal of Oral Medicine and Pain
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• 제26권3호
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• pp.215-224
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• 2001

서울대학교 치과병원 구강진단과에 구강건조증을 주소로 내원한 환자중 비자극 전타액 분비율이 0.2ml/min이하인 환자 40명과 구강건조증의 증상 및 징후가 없고 정상 타액분비율을 보이는 10명을 대상으로 비자극 전타액 분비율을 측정하고 타액선 스캔 검사를 실시하여 주타액선의 스캔 영상을 정량화한 후 이의 상관관계를 조사한 결과 다음과 같은 결론을 얻었다. 1. 구강건조증 환자군 및 정상 대조군에서 타액선 스캔 영상의 정량적 분석시 이하선 및 악하선 모두에서 좌우측 사이의 유의성 있는 차이가 없었다. 2. 타액선 스캔 영상의 정량적 분석시 구강건조증 환자군은 대조군에 비하여 악하선, 이하선 및 악하선의 합, 양측 악하선 합에서 유의한 차이를 보였다. 3. 대조군에서 타액선 스캔 영상의 정량적 수치와 비자극 전타액 분비율과는 유의성 있는 상관관계가 관찰되지 않았으나, 구강건조증 환자군에서는 유의성 있는 상관관계가 관찰되었다. 4. 구강건조증 환자군을 비자극성 전타액 분비율에 따라 세분하였을 때, 비자극 전타액 분비의 감소가 극심하여 그 측정이 불가능하였던 군은 대조군 및 나머지 구강건조증 환자군에 비하여 타액선 스캔 영상의 정량적 수치에서 유의한 차이를 보였다.

• 동의생리병리학회지
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• 제18권5호
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• pp.1397-1403
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• 2004

By recently study, GM (Gamipaemo-tang) treatment have worked well on the allergic asthma. The purpose of this study was effect of GM extract on helper T cell, major regulator of immune system. Splenic cells from 8-week BALB/c mice were cultured in GM containing media without activation for 48 hours. The MTS assay and flow cytometry study revealed that lymphocyte treated with GM were not effective on CD4+ T cells. Subsequently CD4+ T cells were isolated and cultured in GM containing media. Either GM were not effective on CD4+ T cell without APCs. By FACS scan analysis, the expression of INF-γ, IL-4 were down-regulated in the condition skewed Th1 and Th2 cells respectively, Using ELISA analysis, the expression of INF-γ is up-regulated and IL-4 is down-regulated in the condition skewed Th1, Th2 cells respectively. With RT-PCR analysis, the expression of mRNA for INF-γ is down-regulated and IL-4 is down-regulated in the condition skewed Th1 and Th2 cells respectively. The result suggests that GM inhibited the differetiation of Th2 cells significantly and indicates GM could enhance anti-allergic immune system.

• 한국재료학회지
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• 제24권6호
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• pp.285-292
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• 2014

Commercial activated-carbon used as the electrode material of an electric double-layer capacitor (EDLC) was posttreated with various acids and alkalis to increase its capacitance. The carbon samples prepared were then heat-treated in order to control the amount of acidic functional groups formed by the acid treatments. Coin-type EDLC cells with two symmetric carbon electrodes were assembled using the prepared carbon materials and an organic electrolyte. The electrochemical performance of the EDLC was measured by galvanostatic charge-discharge, cyclic voltammetry, and electrochemical impedance spectroscopy. Among the various activated carbons, the carbon electrodes (CSsb800) prepared by the treatments of coconutshell-based carbon activated with NaOH and $H_3BO_5$, and then heat treated at $800^{\circ}C$ under a flow of nitrogen gas, showed relatively good electrochemical performance. Although the specific-surface-area of the carbon-electrode material ($1,096m^2/g$) was less than that of pristine activated-carbon ($1,122m^2/g$), the meso-pore volume increased after the combined chemical and heat treatments. The specific capacitance of the EDLC increased from 59.6 to 74.8 F/g (26%) after those post treatments. The equivalent series resistance of EDLC using CSsb800 as electrode was much lower than that of EDLC using pristine activated carbon. Therefore, CSsb800 exhibited superior electrochemical performance at high scan rates due to its low internal resistance.

• 대한의용생체공학회:의공학회지
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• 제28권3호
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• pp.338-343
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• 2007

BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. These observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.

• Journal of Acupuncture Research
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• 제15권2호
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• pp.301-310
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• 1998

Infrared thermographic imaging visualizes noninvasively various abnormal condition by detecting the skin temperature. As the imaging represents the objective condition by the changes in blood flow under the control of autonomic nervous system, it is used to diagnosis and monitor the lumboscral radiculopathy. And asymmetry is important in the diagnosis of disc herniation. The most common type of disc herniation occurs psoterolaterally. This frequently causes nerve root compression leading to a radiculopathy in the distribution of the involved nerve root, most of which also provoke the asymmetric changes in thermography. Central disc herniation, which accounts for 5% to 35% of disc herniation, is typically associated with low back pain. But radiculopathy is usually abscent unless central disc heriniaton is large enough to cause compression of the cauda equina. To evalute the diagnostic value of the thermographic imaging in the diagnosis of central disc herniation, the imaging of 15 normal subjects and 48 patients with central disc herniation documented by CT scan were analyzed. The patients had either bilateral radiculophathy or no radiculopathy. The imaging of patient group with non rediculopathy did not show any significant thermal difference to control. While bilateral radiculopathy group reveled hypothermic pattern compared twith control. Thermal difference between left and right side did not present any significance in non radiculopathy group but hypothermia in bilateral radiculopathy group. Large herniation group demonstrated hyperthemic pattern while the others showed no significant change. Cranial caudal thermal difference did not show any difference between experiment groups. These results shows that infrared thermographic imaging can be used central disc herniation with bilateral radiculopathy, while it seems to little useful on the diagnosis of non radiculopathic disc herniation.

• 한국전기전자재료학회논문지
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• 제17권8호
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• pp.875-881
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• 2004

Fundamental results obtained from an atomic force microscope (AFM) chemically-induced direct nano-lithography process are presented, which is regarded as a simple method for fabrication nm-scale devices such as superconducting flux flow transistors (SFFTs) and single electron tunneling transistors (SETs). Si cantilevers with Pt coating and with 30 nm thick TiO coating were used as conducting AFM tips in this study. We observed the surfaces of superconducting strip lines modified by AFM anodization' process. First, superconducting strip lines with scan size 2 ${\mu}{\textrm}{m}$${\times}$2 ${\mu}{\textrm}{m}$ have been anodized by AFM technology. The surface roughness was increased with the number of AFM scanning, The roughness variation was higher in case of the AFM tip with a positive voltage than with a negative voltage in respect of the strip surface. Second, we have patterned nm-scale oxide lines on ${YBa}-2{Cu}_3{O}_{7-x}$ superconducting microstrip surfaces by AFM conductive cantilever with a negative bias voltage. The ${YBa}-2{Cu}_3{O}_{7-x}$ oxide lines could be patterned by anodization technique. This research showed that the critical characteristics of superconducting thin films were be controlled by AFM anodization process technique. The AFM technique was expected to be used as a promising anodization technique for fabrication of an SFFT with nano-channel.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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• pp.111-111
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• 2001

목적： To evaluate the feasibility of the event-related functional MR study using power grip studying the hand motor system 대상 및 방법： Event-related functional MRI was performed on a 1.5T MR unit in seven norm volunteers (man=7, right-handedness=2, left-handedness=5, mean age： 25 years). A single-shot GRE-EPI sequence (TR/TE/flip angle： 1000ms/40ms/90, FOV = 240 mm matrix= 64$\times$64, slice thickness/gap = 5mm/0mm, 7 true axial slices) was used for functiona MR images. A flow-sensitive conventional gradient echo sequence (TR/TE/flip angl 50ms/4ms/60) was used for high-resolution anatomical images. To minimize the gross hea motion, neck-holders (MJ-200, USA) were used. A series of MR images were obtained in axial planes covering motor areas. To exclude motion-corrupted images, all MR images wer surveyed in a movie procedure and evaluated using the estimation of center of mass of ima signal intensities. Power grip task consisted of the powerful grip of all right fingers and hand movement ta used very fast right finger tapping at a speed of 3 per 1 second. All tasks were visual-guid by LCD projector (SHARP, Japan). Two tasks consisted of 134 phases including 7 activatio and 8 rest periods. Active stimulations were performed during 2 seconds and rest period were 15 seconds and total scan time per one task was 2 min 14 sec. Statistical maps we obtained using cross-correlation method. Reference vector was time-shifted by 4 seconds an Gaussian convolution with a FWHM of 4 seconds was applied to it. The threshold in p val for the activation sites was set to be 0.001. All mapping procedures were peformed usin homemade program an IDL (Research Systems Inc., USA) platform. We evaluated the activation patterns of the motor system of power grip compared to hand movement in t event-related functional MRI.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.97-97
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• 2003

Contrast-enhanced MR angiography (CE-MRA) gradually occupies its position as a primary evaluation tool forsteno-occlusive disease of supra-aortic cervical arteries. It has several advantages over time-of-flight (TOF) technique such as shorter imaging time, less saturation effect, and less flow- and motion-related artifacts. Diverse methods of k-space sampling, imaging sequences, and strategies for image acquisitiontiming have been introduced since its early clinical application. Especially, methods of k-space sampling and image acquisition timing are very important to achieve maximal arterial enhancement and suppress venous signal while maintaining large scan coverage and high spatial resolution. In addition, regardless of several advantages over TOF technique, it still has a tendency to overestimate the degree of stenosis in patients with carotid or vertebralartery disease. In this exhibit, we will overview the current techniques of CE-MRA with special attention to methods of k-space sampling and image acquisition timing. We will also discuss diagnostic accuracy of CE-MRA in patients with supra-aortic cervical artery stenosis and artifacts frequently misinterpreted as steno-occlusive lesion on CE-MRA.

• 한국융합학회논문지
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• 제6권5호
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• pp.287-294
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• 2015

본 연구의 목적은 급성기 허혈성 뇌졸중 환자의 뇌 관류 CT검사 시 피폭선량을 알아보고자 하였다. 특히, 방사선 감수성이 높은 장기들의 장기선량(Organ dose)을 팬텀과 유리선량계를 이용하여 실측해보고, 제조사가 제시한 기존 프로토콜(고정시간기법)과 새로 제시한 융합 프로토콜(조영제 추적기법)을 적용하여 선량을 측정하여 보고, 피폭선량 저감화 방안을 마련하고자 하였다. 분석결과 기존 프로토콜과 비교하여 새로 제시한 융합 프로토콜에서 최고 39.8 %, 최저 5.8 % 장기선량이 감소하였고, 검사 피폭선량인 $CDTI_{vol}$과 DLP 값은 각각 25 % 감소하였으며, 권고 선량 이하로 측정되었다. 위의 분석결과를 바탕으로 기존에 제시된 프로토콜을 점검해보고, 새로 제시한 융합 프로토콜을 적용하여 피폭선량을 감소시켜 국민보건향상에 이바지 해야 할 것이며, 다른 검사에서도 최적의 프로토콜을 찾기 위한 연구가 계속되어져야 할 것으로 사료된다.