• Journal of Biomedical Engineering Research
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• v.43 no.2
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• pp.71-80
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• 2022

The interaction between dual-ligand decorated particle-based delivery system and target cell under shear flow is predicted using probability model developed. We assumed the two kinds of ligand are decorated on the surface of the particle with 10% length difference. Fixed with other biophysical parameters, a study on the particle-cell interaction for the different non-specific interaction parameter is performed. To induce the firm adhesion, short ligand-receptor should be engaged. Also, it is shown that the rational design of ligand-receptor interaction, including receptor number, specific interaction parameter, kinds of ligand-receptor, etc., should be considered.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.9
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• pp.192-203
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• 2001

The design of gate and runner(delivery system) is one of the most important subject in injection molding. Delivery system is a channel to flow the polymer melt from the injection molding machine to the mold cavities. Also, delivery system affect quality and productivity of the part. The synthesis of delivery system of injection molding has been done empirically, since it requires profound knowledge about the moldability and causal effects on the properties of the part, which are not available to designers through the current CAD systems. GATEWAY is a knowledge module which contains knowledge to permit non-experts as well as mold design experts to generate the acceptable geometries of gate and runner far injection molded parts. A knowledge-based CAD system is constructed by adding the knowledge module, GATEWAY, to an existing geometric modeler. A knowledge-based CAD system is a new tool which enables the concurrent design and CIM with integrated and balanced design decisions at the initial design of injection molding.

• Proceedings of the Korean Society of Agricultural Engineers Conference
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• 2005.10a
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• pp.534-539
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• 2005

The purpose of this study is the introduction of pollutant loads's estimation into Saemangeum watershed area with M.E.'s guidebook for TMDL and GIS tool. To estimate reliable pollutants loads, it is necessary to think about characteristic of removal, discharge and runoff as time series. In this study, it was calculated for generation loads which be came from pollutant source, discharge loads which be reduced in the treatment facilities and delivery loads which be considered the self purification parameter and delivery distance. To assess the delivery distance handily, it was particularly estimated using Arc-GIS. It was met with good results that delivery loads of BOD, T-N and T-P was reflected to seasonal precipitation. Lastly to verify the estimated pollutant loads, HSPF developed by USEPA was applied to it. It was showed a relativity of observed to simulated data for flow, Temperature, DO, BOD, $NO_3^--N$ TN and TP. Consequantly, this delivery loads can make full use of model input data for prediction of pollutant loads.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.169-170
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• 2010

• Tuberculosis and Respiratory Diseases
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• v.82 no.1
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• pp.86-87
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• 2019

• Journal of Pharmaceutical Investigation
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• v.25 no.1
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• pp.55-62
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• 1995

W/O and O/W emulsions of tegafur (50 mg/5 ml/kg) were orally administered to rats to compare with their mesenteric lymphatic delivery effects. And also in order to demonstrate the lymph targeting associated to the oral route, it was deemed necessary to investigate the fate of solution after oral administration as a control. Lymph and plasma samples were periodically taken from each subject of mesenteric lymphatic duct cannulated rats. Then, lymph and plasma levels of tegafur and its active metabolite, 5-FU, were simultaneously observed. Also pharmacokinetic parameters were compared with each others. On the other hand, most previous studies of lymphatic transport have not addressed the question of whether an increase in mesenteric or thoracic lymph transport by the manipulation of a suspected variable was due to a selective delivery to the intestinal lymphatics or an overall increase availability. Therefore, based on a physiologically based pharmacokinetic model which represents the characteristics of lymphatic systems, we are also going to determine the contributions of mesenteric lymph transport versus thoracic lymph transport of tegafur reported in reference(13). In comparison with tegafur solution, AUC and mean residence time of plasma tegafur were significantly increased in W/O emulsion but significantly decreased in O/W emulsion. Lymph flow rates were similar in both solution and W/O emulsion but half in O/W emulsion. AUC of tegafur in mesenteric lymph and in plasma for W/O emulsion were 3.7 times and 2.9 times more than those for O/W emulsion, respectively. And AUC of 5-FU in thoracic lymph for W/O emulsion was 3.7 times more than that for O/W emulsion. These results suggested that lymphatic delivery or tegafur by W/O emulsion was more effective than that by on emulsion due to its differences or formation ability of chylomicrons.

• Proceedings of the KSRS Conference
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• v.2
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• pp.808-811
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• 2006

The KOMPSAT-2 was developed by KARI and it was successfully launched from Plesetsk, Russia on 28th July 2006. The Korean government decided the commercialization of the KOMPSAT-2 image data and direct reception services worldwide. SPOT Image, based in Toulouse (France) was selected by KARI through an international open bidding as a foreign company for the KOMPSAT-2 image promotion over the entire world except the territory of Republic of Korea including the North Korea, the United States of America, UAE, Saudi Arabia, Kuwait, Qatar, Oman, Yemen, Egypt, Iran, Iraq, Jordan, Lebanon, and Syria. KAI (Korea Aerospace Industry Ltd.) is an engaged Korean company for this area. KARI has responsibility to operate the satellite, data acquisition, archiving for the worldwide commercialization. For the processing and delivery of the KOMPSAT-2 image data to the users of KAI and SPOT Image, KAI has the binding contract with KARI. So KAI has the responsibility for the commercial ground station operation such as user support, data processing, and the data delivery. The KOMPSAT-2 ground station is hosted in KARI, so KARI has developed the concept of KOCUST (KOMPSAT-2 Commercial User Support Team) jointly with KAI to support the data processing and delivery as KOMPSAT-2 developer and satellite operator. The main purpose of the KOCUST is to support the operational activities to provide the data and service quality to satisfy customers. KOCUST will be organized by the members of KARI and KAI together. KARI members will mainly take the role of KOCUST coordination, data processing and user support in a public sector. KAI members are going to take user desk, data validation and delivery et cetera, which are related with users. This paper describes a summarized concepts of KOCUST like organization, dedicated tasks of each part and work flow of daily operation.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.7
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• pp.2257-2265
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• 1996

In the cold rolling mill, it is very important that a constrained static flow stress of rolled strip and rolling force calculation model be exactly considered to improve an prediction accuracy for rolling forces. Therefore, in this study, the values of the constrained static flow stress are used by deriving the regression equation which is a function of rolling conditions(FDT, CT) and chemical compositions(C, Si, Mn), previously applied by making the tables of yield strength for hot coils with size. And with the consideration that an elastic deformation part of an rolled strip appears at the entry and delivery side of the contacting area between the work roll and rolled strip is calculated. By applying these methods, the more accurate prediction for rolling force is obtained. As a results, the deviation of thickness is significantly reduced in the rolling direction.

• Journal of KIISE:Information Networking
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• v.41 no.4
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• pp.167-176
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• 2014

In this paper, we discuss the implementation and experimentations of a new future Internet architecture for mobile-oriented environments, named Mobile Oriented Future Internet (MOFI). The MOFI architecture is featured by the host identifier and local locator for identifier-locator separation, Query-First Data Delivery (QFDD), and Distributed Mapping System (DMS) for identifier-locator mapping control. In the existing study on MOFI, we examined the intra-domain mobility control, the implementation of MOFI over Linux platform, and the performance analysis over the small-scale testbed. In this paper, we describe how to implement the MOFI architecture for inter-domain mobility control by using the OpenFlow and Click Modular Router platform. From the experimentations over the KOREN testbed, we can see that the MOFI scheme can give better performance than the existing Proxy Mobile IP scheme.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.8
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• pp.5363-5368
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• 2014

This study examined contribution rate on the Soyangho Lake watershed based on the flow regime, and seasonal change was evaluated by calculating the delivery pollution load of the drainage area of Soyangho Lake watershed. According to the contribution rate of the drainage area by the flow regime change, Inbukcheon Creek watershed's SS and T-P entry have recorded abnormal Six month flow and a contribution rate of 46% and 51% during the Low-water flow period. At the same time, the T-P recorded a 49.5% contribution rate and a contribution rate of 48.5% during the Low-water flow period. In sequence, Inbukcheon creek's SS entry recorded a comparatively higher contribution rate than the other drainage area, which are 39.6% and 44.3% during the entire season and 53.8% for T-P, as a result of observing the contribution rate based on the seasonal changes. The T-N at the Naerincheon Creek watershed for the entire season recorded a contribution rate between 39.6% and 44.3%. Overall, Inbukcheon Creek watershed's SS and T-P entry and Naerincheon creek's T-N had a high contribution rate on contaminant spill.