• Advances in nano research
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• v.14 no.3
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• pp.247-259
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• 2023

Muscle strength and hypertrophy are equivalent when low-intensity resistance exercise is paired with blood flow restriction. This paper deals with the impact of physical exercise in the form of body activities on drug delivery using nanodevices. The body's actions impact the blood flow since the nano drug delivery devices are released into the bloodstream, and physical exercise and all the activities that change the blood flow influence the stability of these nanodevices. The nanodevice for the drug delivery purpose is modeled via nonuniform tube structures based on the high-order beam theory along with the nonlocal strain gradient theory. The nanodevice is made by a central nanomotor as well as two nanoblade in the form of truncated conical nanotubes carrying the nanomedicine. The mathematical simulation of rotating nanodevices is numerically solved, and the effect of various parameters on the stability of nanodevices has been studied in detail after the validation study.

• 한국금형공학회:학술대회논문집
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• 2008.06a
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• pp.155-158
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• 2008

Flow imbalance among the cavities was often observed in multi-cavity mold. The flow imbalance affects on the dimensions and physical properties of molded articles. First of all, the origin of flow imbalance is geometrical imbalance of delivery system. However, even the geometry of delivery system is balanced the cavity imbalance is being developed. This comes from the temperature distribution in the cross-section of runner, which is affected by the operational conditions. In this study, experimental study of flow imbalance has been conducted for various injection speeds. This study also suggests new runner design to eliminate flow imbalance in multi-cavity injection mold. Simulation and experimental results showed suggested new designed runner could eliminate or reduce flow imbalance in multi-cavity injection mold.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2008.05a
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• pp.329-332
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• 2008

Flow imbalance among the cavities was often observed in multi-cavity mold. The flow imbalance affects on the dimensions and physical properties of melded articles. First of all, the origin of flow imbalance is geometrical imbalance of delivery system. However, even the geometry of delivery system is balanced the cavity imbalance is being developed. This comes from the temperature distribution in the cross-section of runner, which is affected by the operational conditions. In this study, experimental study of flow imbalance has been conducted for various injection speeds. This study also suggests new runner design to eliminate flow imbalance in multi-cavity injection mold. Simulation and experimental results showed suggested new designed runner could eliminate or reduce flow imbalance in multi-cavity injection mold.

• Magazine of the Korean Society of Agricultural Engineers
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• v.39 no.6
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• pp.67-79
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• 1997

The perpose of this study was to suggest the experimental characteristic of the Cherepnov Water Lifter following the drain mode. The Cherepnov Water Lifter(CWL), which is powered by the potential energy of water, can be set to operate automatically when the water m a tank is drained. In this study, a CWL is constructed in the valve drain controlling mode(VCM) and the siphon drain controlling mode(SCM), and a pressure transducer is installed. It was found that, in the VCM, intake flow volume is proportional to both delivery flow volume and drain flow volume. In the SCM, intake flow volume is proportional to drain flow volume, and the average delivery rate is proportional to both efficiency and the water utilization ratio. Also, in the VCM, the water utilization ratio is 35~49%, efficiency is 62~9O%, average delivery rate is 12.8~81.2$cm^3$/s, and the average drain rate is 14.O~91.5c$cm^3$/s. On the contrary in the SCM, the water utilization ratio is 1.7~38%, efficiency is 3~58%, average delivery rate is 3.1 ~69.2$cm^3$/s, and the average drain rate is shown as 114.5~ 183$cm^3$/s. As a result of the water utilization ratio, efficiency, average delivery rate, and average drain rate are compared, the VCM is found to be superior and the more economical mode. However, the VCM requires manpower and electricity to operate the electronic machinery involved, while the SCM requires no manpower or electricity at all. An economic evaluation of these differences will be necessary in the future. Also, in the SCM, studies to improve water utilization ratio and efficiency, to find the optimum height of the siphon for decreasing the average drain rate, and to determine the radius of curvature of throat have to be conducted in advance, since a large flow rate is drained during the priming action of the siphon.

• Journal of Korean Society on Water Environment
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• v.25 no.3
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• pp.375-385
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• 2009

The estimation of delivery ratio is a essential part of Korean Total Maximum Daily Loads (TMDL) procedure which needs a number of observed stream flow and pollutants data. If observed data were not sufficient, researchers have to find other alternatives. One of them is to make indirect data by using watershed models, such as Soil and Water Assessment Tool (SWAT) and Hydrological Simulation Program - FORTRAN (HSPF) and so on. In this study, indirect daily data was made by using SWAT model. To build the Byongseong-SWAT model accurately, crop cultures are reflected by handling the MGT.file in SWAT model. Especially, mass of manure and schedule of crop culture are inputted through investigating domestic research papers as well as fieldwork. After calibrating SWAT model in comparison with the 22-years flow and pollutants observed outlet data, the delivery ratio of Byongseong watershed is calculated by using daily simulated data during 2004-2007. Empirical equations for delivery ratio through multi-regression analysis are developed by using meteorological and physical factors such as flow, watershed area, stream length, catchment slope, curve number (CN) and subbasin's pollutant discharge loads.

• Journal of the Korean Society for Precision Engineering
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• v.34 no.2
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• pp.101-106
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• 2017

The chemical mechanical planarization (CMP) process combines the chemical effect of slurry with the mechanical effect of abrasive (slurry)-wafer-pads The slurry delivery system has a notable effect on polishing results, because the slurry distribution is changed by the supply method. Thus, the investigation of slurry pumps and nozzles with regard to the slurry delivery system becomes important. This paper investigated the effect of a centrifugal slurry pump on a spray nozzle system in terms of uniform slurry supply under a rotating copper (Cu) wafer, based on experimental results and computational fluid dynamics (CFD). In conventional tools, the slurry is unevenly and discontinuously supplied to the pad, due to a pulsed flow caused by the peristaltic pump and distributed in a narrow area by the tube nozzle. Adopting the proposed slurry delivery system provides a higher uniformity and lowered shear stress than usual methods. Therefore, the newly developed slurry delivery system can improve the CMP performance.

• Journal of the Korean Operations Research and Management Science Society
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• v.28 no.1
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• pp.1-10
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• 2003

A recent trend In flexible manufacturing systems (FMS) Is to utilize the Identical versatile machines with fast tool delivery devices. Unlike a conventional FMS where parts are fed to the machines with the required tools, tools are acquired from other machines using a tool delivery system and parts can be finished on the same machine In these FMS. Therefore it Is more important problem 4o plan tool flow using tool delivery system In these FMS rather than part flow In conventional FMS. According to the existing study, In FMS 20∼30 percent of the total management cost Is the cost related with tools and It Is possible to reduce the tool Inventory by 40 percent using efficient tool allocation. In this study, In FMS under dynamic tool allocation strategy, a new method of part release considering tool flow at the stage of part release Is proposed. In order to prove the efficiency of the proposed part release It is compared with other part release through simulation experiments. Performance measures in these experiments are the throughput and the number of tardy parts.

• International Journal of Fluid Machinery and Systems
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• v.7 no.4
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• pp.160-173
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• 2014

Surge phenomena in multi-stage axial flow compressors were studied with attention to the frequency behaviors. A new parameter "volume-modified reduced surge frequency" was introduced, which took into consideration the essential surge process, i.e., emptying and filling of the working gas in the delivery plenum. The behaviors of the relative surge frequencies at the stall stagnation boundaries, compared with the corresponding duct resonance frequencies, have demonstrated the existence of two types of surges; i.e., a near-resonant surge and a subharmonic surge. The former, which has fundamentally a near-resonance frequency, occurs predominantly at the stall stagnation boundary for the short -and-fat plenum delivery flow-path and the long-and-narrow delivery duct flow-path, and possibly in the intermediate conditions. The latter, which has a subharmonic frequency of the fundamental near-resonant one and occurs mainly in the intermediate zone, is considered to be caused by the reduced frequency restricted to a limited range. In relation with those dimensionless frequencies at the stall stagnation boundary, the surge frequency behaviors in more general situations away from the boundaries could be estimated, though very roughly.

• Journal of the Korean Society of Visualization
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• v.10 no.2
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• pp.32-38
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• 2012

In recent years a unique drug delivery system named as the transdermal drug delivery system has been developed which can deliver drug particles to the human skin without using any external needle. The solid drug particles are accelerated by means of high speed gas flow through a shock tube imparting enough momentum so that particles can penetrate through the outer layer of the skin. Different systems have been tried and tested in order to make it more convenient for clinical use. One of them is the contoured shock tube system (CST). The contoured shock tube consists of a classical shock tube connected with a correctly expanded supersonic nozzle. A set of bursting membrane are placed upstream of the nozzle section which retains the drug particle as well as initiates the gas flow (act as a diaphragm in a shock tube). The key feature of the CST system is it can deliver particles with a controllable velocity and spatial distribution. The flow dynamics of the contoured shock tube is analyzed numerically using computational fluid dynamics (CFD). To validate the numerical approach pressure histories in different sections on the CST are compared with the experimental results. The key features of the flow field have been studied and analyzed in details. To investigate the performance of the CST system flow behavior through the shock tube under different operating conditions are also observed.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.477-478
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• 2006

Close-coupled atomizers are of great interest and controlling their performance parameters is critical for metal powder producing and spray forming industries. In this study, designed close-coupled nozzle systems were used to investigate the effect of the nozzle types and protrusion length of the melt delivery tube on the pressure formation at the melt delivery tube tip. The observed metal flow rate was not behaving as what was earlier assumed, namely that, deeper aspiration enhanced metal flow rate. Higher aspiration pressure at the tip of the melt delivery tube increases the stability of atomization process.