• 제목/요약/키워드: Flow characteristic analysis

검색결과 790건 처리시간 0.026초

Induction of Apoptosis with Kigelia africana fruits in HCT116 Human Colon Cancer Cells via MAPKs Signaling Pathway

  • Guon, Tae-Eun;Chung, Ha Sook
    • Natural Product Sciences
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    • 제22권3호
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    • pp.209-215
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    • 2016
  • Kigelia africana (Lam.) Benth. (Bignoniaceae) is a flowering plants in South, Central and West Africa and commonly known as the sausage tree (Eng.); worsboom (Afr.); umVunguta, umFongothi (Zulu); Modukguhlu (North Sotho); Muvevha (Venda). The dried, powdered fruits are used as dressing for wounds and ulcers, haemorrhoids, rheumatism, purgative, skin-firming, lactation in breast-feeding mothers. The aim of this study is to investigate the cytotoxic and apoptotic potentials of 70% ethanolic extracts of Kigelia africana fruits in HCT116 human colon cancer cells. Treatment of Kigelia africana fruits with various concentrations resulted in a sequence of characteristic of apoptosis, including loss of cell viability and morphological changes. Flow cytometry analysis showed Kigelia africana fruits increased the sub-G1 phase (apoptosis) population. Apoptosis confirmed by annexin V-fluorescein isothiocyanate and propidium iodide double staining in HCT116 human colon cancer cell lines. Moreover, analysis of the mechanism indicated that Kigelia africana fruits showed an increased Bax and Bcl-2 expressions in a dose-dependent manner, resulting in activation of hallmarks of apoptotic events, caspase-3, caspase-9 and cleaved poly-ADP-ribose polymerase. This is the first report to demonstrate the cytotoxicity of Kigelia africana fruits on HCT116 human colon cancer cells.

스팀터빈용 래비린스 실의 누설량 규명을 위한 공기상사 실험 및 해석 (Air Similarity Test and Analysis of Steam Turbine Labyrinth Seal for Leakage Verification)

  • 안상규;김승종;이용복;김창호;하태웅
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2006년도 춘계학술대회논문집
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    • pp.1149-1149
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    • 2006
  • The leakage characteristic is an important factor in power plant. However, most of power plant have efficiency problem which is occurred leaking between high pressure steam turbine axle and stator. The labyrinth seal which is used between the main turbine axle and stator in the power plant. Because it is able to be non-contact seal and it is minimize clearance to decrease the leakage. But its actual system is too huge to experiment. Therefore, most steam turbine seal performance tests were conducted by air similarity test. This paper described a test facility and program for air similarity test of high pressure steam turbine seal. A test facility has been designed and built to evaluate leakage verification of labyrinth seal. The test facility consist of air compressor, anti-swirl labyrinth seal for 1/3 air similarity model, pressure transducer, air flow measure system, instrumentation and auxiliary system. For evaluation of steam turbine seal performance, the air similarity test of labyrinth seal leakage verification was conducted and we compared experiment data and analysis result.

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지역냉방 시스템용 판형 열교환기의 주름높이에 따른 열전달 및 압력강하 특성 (Heat Transfer and Pressure Drop Characteristic of Plate Heat Exchanger with Corrugation Height for District Cooling System)

  • 권오경;김현중
    • 한국지열·수열에너지학회논문집
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    • 제7권2호
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    • pp.23-29
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    • 2011
  • The objectives of this paper are to study the characteristics of heat transfer and pressure drop of the plate heat exchanger with corrugation height by numerical analysis. Plate heat exchanger of three types was designed, which was corrugation height 3.1mm, 2.8mm and 2.5mm. The plate heat exchanger was numerically investigated for Reynolds number in a range of 950~3,380. The temperatures of the hot side were performed at $14.5^{\circ}C$ while that of the cold side was conducted at $4.5^{\circ}C$. The results show that the performance of heat transfer coefficient for corrugation height 2.5mm increases about 9.5~17.1% compared to that of corrugation height 3.1mm. On the other hand, the performance of pressure drop for corrugation height 2.5mm is remarkably higher than that of corrugation height 3.1mm, about 65.7~86.0%.

7구역진단기의 임상응용에 대한 고찰 (2) - 각 제품에 따른 원리와 판독의 비교 - (A Study on the Clinical Use of 7-zone-Diagnostic System (2) - the Comparative Analysis of the Rule and the Decipher for each Equipment -)

  • 송범용
    • Journal of Acupuncture Research
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    • 제23권5호
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    • pp.11-21
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    • 2006
  • The 7-zone-diagnostic system(ABR-2000, BIO MEDIC 700Plus, CP-6000A, OMD 3000, VEGA-DFM 722) is a diagnostic device which applies pulse signals to predetermined bodily locations. Applying alternating positive and negative stress to tissues with positive and negative pulses first manifests itself as negative and positive wave forms. This system make a diagnosis of functional disorder or some typical organic diseases include stress of the mind or the body, and the energetic situation, reserves. We are known a disorder or disease throw the result charts. And these result represents various characteristic signals are assisted diagnosis and care. These result chart contains disorder flow wave forms and some valuable diagnostic hints or marks. But we have several various products for the 7-zone-diagnostic system. I think that we need the comparative analysis of the general rule and the decipher for each equipment. Because these letters(marks) each product are different, we necessary various plentiful research and suitable statistics in these points. And we must carry out many various research in the future.

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조정지댐에 유입하는 도시하천 오염특성에 관한 연구 (A Study on Pollution Property of Urban River Inflow in Regulating Reservoir)

  • 장인수;박기범;이원호
    • 한국환경과학회지
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    • 제15권10호
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    • pp.935-943
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    • 2006
  • This study focuses on analyzing the inflow characteristic of contaminants of city water that flows into a main water system like a reservoir, and intends to provide basic data which can be efficiently reflected on water quality management policy and decision making of a reservoir. The conclusion obtained from the analysis of the inflow of a main water system by analyzing the inflow property of city water contaminants is as follows. In the case of Chungju-cheon stream which is the city water, pollution load from the basic outflow is low when it rains, and with high load of basic outflow during the dry season, due to the discharge of pollutants from the city, the quality of water becomes worse. In the case of Chungju-cheon stream, average BOD is $4.53mg/{\ell}$ when it rains, and the contaminants increase and flow in about 7.8% compared to the average BOD during the average droughty season. The average SS concentration in water is $798.67mg/{\ell}$ and increased 97.2% compared to the average droughty season.

함수특성곡선을 고려한 불포화토 사면의 안정성 연구 (A study on the Stability Analysis of Slope in Unsaturated Soil Based on the Soil-Water characteristic curve)

  • 윤민기;김종성;김효중;이영생
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2008년도 추계 학술발표회
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    • pp.1029-1037
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    • 2008
  • The finite element analysis of transient water flow through unsaturated soils was used to investigate effects of hydraulic characteristics, initial relative degree of saturation, methods to consider boundary condition, and rainfall intensity and duration on water pressure in slopes. The finite element method with shear strength reduction technique was used to evaluate the stability of slopes under rainfall. The slope-related disasters in Korea usually occur between July and September during the typhoon and localized heavy rain. This means that the rainfall is the most important factor that leads to the slope-related disasters. The slope-related disasters can happen at very short time and lead to big damage. To forecast the change of the heave of the groundwater in slope the Seep/w program was used.

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반원관내 자성유체의 유동에 관한 연구 (A Study on the Flow Behavior of Magnetic Fluids in a Closed-semicircular Pipe)

  • 황성욱;박정우;서이수
    • 한국자기학회지
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    • 제17권6호
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    • pp.253-258
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    • 2007
  • 본 연구에서는 밀폐된 반원관내 자성유체의 자연대류 현상을 수치적으로 연구하였다. 수치해석방법은 Siliomis의 GSMAC법을 이용하였다. 자성유체의 자연대류 현상을 수치 해석적으로 규명하여, 자성유체의 열역학적 특성을 연구하고자 하였다. 특히 열전달 해석방법으로 온도분포 및 고온벽면의 Nusselt 수를 통하여 속도 벡터와 함께 고찰 하였다. 이로 인하여, 외부 자장에 의한 세기는 자연대류 현상을 촉진 또는 억제하므로, 열전달 문제에 있어서 열의 제거에 있어서 효과적인 방법을 찾게 되었다.

FMEA를 활용한 재제조 파워스티어링 오일펌프 시험법에 대한 최적화 연구 (The Optimization Study on the Test Method of Remanufactured Power Steering Oil Pump by Using FMEA)

  • 서영교;정도현;유상석;나완용
    • 한국자동차공학회논문집
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    • 제24권1호
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    • pp.90-98
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    • 2016
  • Currently government certified test method for an automobile remanufactured products is insufficient. Thus many automotive parts in the remanufacturing market are lacking proper evaluation criteria and production of defective products are causing customer dissatisfaction. In this paper a power steering oil pump, which requires stringent manufacturing standards, is studied by the failure mode and effect analysis approach. The research suggested that the test criteria such as discharge flow characteristic test, tightness test, pulley run-out test, pressure switch operation test, low temperature test and rotation pressure durability test should be performed to evaluate the reliability of remanufactured power steering oil pumps. As a result of tests, the performance of remanufactured power steering oil pump satisfied the evaluation criteria of pressure switch operation test and low temperature test. However, the remanufactured power steering oil pump failed to satisfy the evaluation criteria on discharge performance test, tightness test and pulley run-out test. These performance evaluation tests proved the necessity of standard process for the remanufactured power steering oil pump.

Simulation analysis on the separation characteristics and motion behavior of particles in a hydrocyclone

  • Xu, Yanxia;Tang, Bo;Song, Xingfu;Sun, Ze;Yu, Jianguo
    • Korean Journal of Chemical Engineering
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    • 제35권12호
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    • pp.2355-2364
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    • 2018
  • We evaluated the effect of particle size and associated dynamics on a hydrocyclone separation process in order to understand the movement of the particle trajectories inside the hydrocyclone via numerical analysis, with particles of acid hydrolysis residues discharged in $TiO_2$ production via the sulfate method as a case study. The values obtained from the numerical simulation were successfully compared with those from experimental tests in the literature, allowing a description of the dynamics of the particles, their acting forces, and their relevant properties together with separation efficiency. The results showed that particle motion is jointly controlled by the drag force, the pressure gradient force and the centrifugal force. With increasing particle size, the influence of the drag force is weakened, whereas that of the centrifugal force and pressure gradient is strengthened. Factors including particle density, slurry viscosity, and inlet slurry flow rate also contribute to a clear and useful understanding of particle motion behavior in the hydrocyclone as a method for improving the separation efficiency.

삼천포 화력발전소 방류수로 및 방류해역의 흐름 관측 및 특성분석 (Flow Measurement and Characteristic Analysis in the Effluent Regions of the Samcheonpo Thermal Power Plant(TPP))

  • 조홍연;정신택;강금석
    • 한국해안해양공학회지
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    • 제18권4호
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    • pp.329-337
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    • 2006
  • 삼천포 화력발전소에서 냉각수로 이용되고 방류되는 해수를 이용한 소수력 발전소가 삼천포 해역에 건설되고 있다. 본 연구에서는 소수력 발전소가 건설되는 지점, 즉 방류수로 및 방류해역의 흐름을 관측하고 흐름특성을 분석하였다. 방류수로의 흐름은 냉각수 방류량에 의한 영향이 지배적이며, 공간적으로는 냉각수가 합류되는 Weir 상류구간, 합류된 냉각수가 방류수로를 통하여 배출되는 Weir 하류구간, 방류해역으로 구분할 수 있다. Weir 상류 지점은 측면에서 유입되는 냉각수로 인하여 유량이 점차 증가하나, 수로의 폭이 증가하기 때문에 수위 변화가 미미한 지역이며, Weir 하류지점은 월류된 냉각수가 사류(super-critical flow)구간을 거쳐서 수리학적 도약으로 인한 강한 연직방향의 요동을 보이며 방류해역으로 이동하는 구간이다. 한편, 방류수에 의한 영향으로 외해방향으로의 해수흐름이 형성되나 유속은 조위의 승강운동에 크게 영향을 받는 것으로 파악되었다. 또한, 방류해역의 조위는 통영 검조소에 비하여 평균조차는 약 10% 크게 나타나고 있으며, 파랑전파에 의한 영향은 미미한 정도로 파악되었다.