• Journal of Korean Society of Transportation
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• v.33 no.4
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• pp.323-336
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• 2015

Estimating the risks on the roadway using surrogate safety measures (SSM) has an advantage in that it focuses on the vehicle trajectory directly involved in conflicts. On the other hand, there is a restriction on estimating the risks of continuous segments due to the limited data collected from a location. To overcome the restriction, this study presents the scheme of acquiring the vehicular trajectory using real time kinematics-differential global positioning system (RTK-DGPS) and develops a methodology which contains the considerations of the problems to calculate the SSM such as time-to-collision (TTC), deceleration rate to avoid collision (DRAC) and acceleration noise (AN). By using the methodology, this study shows a result from an experiment executed in a section where the variation of vehicular movement can be observed from several continuous flow roadway sections near Seoul and Gyeonggi Province in Korea. The result illustrated the risks on the roadway by the SSM metrics in certain situations like merging and diverging, stop-and-go, and weaving. This study would be applied to relate the dangers with characteristics of drivers and roadway sections, and prevenst accidents or conflicts by detecting dangerous roadway sections and drivers' behaviors. This study contributes to improving roadway safety and reducing car-accidents.

• Journal of The Geomorphological Association of Korea
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• v.19 no.2
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• pp.31-49
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• 2012

Satae cheon, a tributary of the Suip cheon in Yanggu, Gangwon province, is an international river extended to North Korea. Most of drainage basin area of the river was the fierce battle field during the Korean War(1950-1953) and hard to access as it located between the MDL(Military Demarcation Line) and the CCZ(Civilian Control Zone: about 10km south from MDL). By the restriction of access to the sites, most of natural landscape have been well conserved except limited use for military activities. Even the landfoms in that area were not studied, except the government's heritage reports. Satae Cheon's channel follows the Imdang fault line(N-S) to Satae-ri and flow to west to the Dutayeon area. The river meanders along geological structure or weak line at the Dutayeon area. The meandering channel was shorten by the meander cut which linked the thalweg line of meander loop ant the meander neck. As a result of this cut, the river cliff formed by the Satae cheon became the part of newly formed channel bed and the S-forms are formed. After the channel route stabilized, channel incised the rock with large potholes and undulating walls were formed. The channel width changes from 1m to 10m with restriction of the undulating walls, so this part can be regarded as inner channel or inner gorge. From the point of planar forms it also can be slot-type canyon.

• The Journal of Fisheries Business Administration
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• v.37 no.2 s.71
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• pp.33-59
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• 2006

This study describes approaches to fisheries management that restrict access by fishers to an area in some way. When fishery closure is established as a technical conservation measure it is a form of input control as a Korea fisheries management system. There are many compelling reasons why a fisheries manager should seriously consider closed areas and/or time restrictions, either as a complement to other measures or as the primary facet of the Korean fisheries management strategy. Fishery closures have been shown to be effective in many fisheries and are an important tool in the management armoury. In many respects justifications for their use and the process of implementation are likely to be relatively straightforward compared to permanent area closures. From a Korean fisheries management perspective, the benefits that flow from fishery closures are usually less easy to predict than for other management measures. Moreover, even if one accepts that implementation of fisherg clossures will provide higher production levels in adjacent fished areas, the potential benefits may often be in danger of being largely dissipated. If, for example, the fishery remains open access, the increased production is likely to attract new entrants into the fishery, thereby driving it back towards bioeconomic equilibrium. From a Korean wider fisheries conservation perspective, however, fishery closures have important and clearly defensible roles to play and some form of zoning arrangement will often effectively serve conservation values. Given the increasing trend towards the establishment of national networks of fisherg closures, it seems likely that fisheries managers throughout the world will need to ensure that they are familiar with the issues surrounding these approaches. The importance of being explicit about the goals for fishery closures in Korea have been continually emphasised throughout this study. There may, of course, be multiple justifications for the measure, in which case it is important to try and specify them in order of priority.

• Investigative Magnetic Resonance Imaging
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• v.21 no.2
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• pp.82-90
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• 2017

Purpose: This study investigated the MRI, MR angiography (MRA) and MR perfusion findings of seizure-related cerebral cortical lesions during the periictal period. Materials and Methods: From a retrospective review of the institutional database between 2011 and 2014, a total of 21 patients were included in this study. Two radiologists assessed periictal MRI, including MRA and MR perfusion, in patients with seizure-related cortical lesions. The parameters examined include: location of cortical abnormality, multiplicity of the affected cortical region, cerebral vascular dilatation, perfusion abnormality and other parenchymal lesions. Results: All patients showed T2 hyperintense cerebral cortical lesions with accompanying diffusion restriction, either unilateral (18/21, 85.7%) or bilateral (3/21, 14.3%). Of the 21 patients enrolled, 10 (47.6%) had concurrent T2 hyperintense thalamic lesions, and 10 (47.6%) showed hippocampal involvement. Of the 17 patients (81%) who underwent MRA, 13 (76.5%) showed vascular dilatation with increased flow signal in the cerebral arteries of the affected cortical regions. On MR perfusion, all 5 patients showed cortical hyperperfusion, corresponding to the region of cortical abnormalities. Conclusion: Seizure-related cerebral cortical lesions are characterized by T2 and diffusion hyperintensities, with corresponding cerebral hyperperfusion and vascular dilatation. These findings can be helpful for making an accurate diagnosis in patients with seizure.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2447-2451
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• 2014

Human papillomavirus (HPV) is the primary etiologic agent of cervical cancer. Consideration of safety and non human leukocyte antigen restriction, protein vaccine has become the most likely form of HPV therapeutic vaccine, although none have so far been reported as effective. Since tumor cells consistently express the two proteins E6 and E7, most therapeutic vaccines target one or both of them. In this study, we fabricated DC vaccines by transducing replication-defective recombinant adenoviruses expressing E6/E7 fusion gene of HPV-16, to investigate the lethal effects of specific cytotoxic T lymphocytes (CTL) against CaSki cells in vitro. Mouse immature dendritic cells (DC) were generated from bone marrow, and transfected with pAd-E6/E7 to prepare a DC vaccine and to induce specific CTL. The surface expression of CD40, CD68, MHC II and CD11c was assessed by flow cytometry (FCM), and the lethal effects of CTL against CaSki cells were determined by DAPI, FCM and CCK-8 methods. Immature mouse DC was successfully transfected by pAd-E6/E7 in vitro, and the transfecting efficiency was 40%-50%. A DC vaccine was successfully prepared and was used to induce specific CTL. Experimental results showed that the percentage of apoptosis and killing rate of CaSki cells were significantly increased by coculturing with the specific CTL (p <0.05). These results illustrated that a DC vaccine modified by HPV-16 E6/E7 gene can induce apoptosis of CaSki cells by inducing CTL, which may be used as a new strategy for biological treatment of cervical cancer.

• Journal of Korea Multimedia Society
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• v.13 no.2
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• pp.279-286
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• 2010

Unbalanced traffic load offered to the nodes making up a path in the network guaranteeing quality-of-service has been known as a main cause deteriorating the capability of the path in admitting traffic flows. Several path load balancing methods have been developed to resolve this problem which used a feedback control scheme that adjusts the delay budget of a flow allocated to each node according to the conditions of available resource in the path. Because of no consideration about the probabilistic characteristics of the service quality, it is impossible for them to prevent in advance a bottleneck on the path which leads to a native restriction in the improvement of the capability being deteriorated. This paper proposes a preventive intra-path load balancing method applicable to the RSVP system which is based on the probabilistic characteristics of the quality-of-service of the offered load. The results of the simulation of the proposed method on a simple evaluation network showed that it provides the gain of 4~22% compared to the legacy one in terms of the number of admitted flows.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.11
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• pp.1559-1571
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• 2008

A rule was developed to constrain the annual rate of inbreeding to a predefined value in a population with different lifetimes between sires and dams, and to maximize the selection response over generations. This rule considers that the animals in a population should be divided into sex-age classes based on the theory of gene flow, and restricts the increase of average inbreeding coefficient for new offspring by limiting the increase of the mean additive genetic relationship for parents selected. The optimization problem of this rule was formulated as a quadratic programming problem. Inputs for the rule were the BLUP estimated breeding values, the additive genetic relationship matrix of all animals, and the long-term contributions of sex-age classes. Outputs were optimal number and contributions of selected animals. In addition, this rule was combined with the optimization of emphasis given to QTL, and further increased the genetic gain over the planning horizon. Stochastic simulations of closed nucleus schemes for pigs were used to investigate the potential advantages obtained from this rule by combining the standard QTL selection, optimal QTL selection and conventional BLUP selection. Results showed that the predefined rates of inbreeding were actually achieved by this rule in three selection strategies. The rule obtained up to 9.23% extra genetic gain over truncation selection at the same rates of inbreeding. The combination of the extended rule and the optimization of emphasis given to QTL allowed substantial increases in selection response at a fixed annual rate of inbreeding, and solved substantially the conflict between short-term and long-term selection response in QTL-assisted selection schemes.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.119-126
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• 2001

This paper analyzes problems related to total cost changes in private investment projects, and then proposes an improvement measure for the control of cost changes within the framework of the project management, contract, human resource, project communication, cost, and time management. From the viewpoint of contract management, the basis of cost change ought to be cleared up with standardization of related provisions in the concession agreement, and potentiality of change ought to be excluded with prescription of the private investor's leading role from the design phase. Regarding human resource management, this paper proposes a standard work flow granting much sovereign rights to private parts by putting restriction on work scopes of the entrusted authority of government, and transferring the rights of assignment, contract, and control about the responsible supervisor to the concessionaire. With regard to project communication management the notification of changes on drawings and technical documents ought to be automated and the realtime database ought to be established with DMIS (Drawings & Documents Management Information System). From the cost management point of view, this thesis integrates the control of cost-change-approved items and disapproved items to one cost breakdown system, and then harmonizes the actual progress with EVMS in time management.

• Journal of KIISE:Information Networking
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• v.30 no.2
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• pp.143-154
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• 2003

There is a growing trend in developing system for distributed mobile system that supports services - job flow management, video conference, replicated data management and resource allocation. Supporting these services, applications have to use causally ordered message delivery. Previous proposals that provide causally ordered message delivery have problems such as communication overhead, message delaying, scalability, computing overload of mobile host. In this paper, we proposed efficient protocol for causally ordered message delivery using the methods that MSS maintains dependency information matrix between MSS and MH, Piggybacking dependency information about each immediate predecessor message. Proposed algorithm, when compared with previous proposals, provides a low message overhead, and low probability of unnecessary inhibition in delivering messages. Also, it consider resource restriction of MH and low bandwidth of wireless communication by computing most of algorithm at MSS, and reduce processing delay by executing causally ordered message delivery a unit of MH.

• Korean Medical Education Review
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• v.10 no.2
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• pp.25-44
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• 2008

Objectives: Through using of the strong research method like a Randomized Controlled Trial: RCT, we have to heighten quality of Medical Education study. I'd like to introduce "CONSORT", which stands for Consolidated Standards of Reporting Trials. Contents: Preventive Service Task Force(200l) in USA proposed Levels of evidence for enlarging evidence-based Practice: EBP. And the CONSORT was introduced, which encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). the CONSORT has 13 guides like these: 1. How participants were allocated to interventions 2. Scientific background and explanation of rationale 3. Eligibility criteria for participants. The settings and locations where the data were collected. 4. Precise details of the interventions intended for each group and how and when they were actually administered 5. Specific objectives and hypotheses 6. Clearly defined primary and secondary outcome measures, When applicable. any methods to enhance the quality of measurements (e.g., multiple observations, training of assessors) 7. How sample size was determined. When applicable, explanation of any interim analyses and stopping rules 8. Method used to generate the random allocation sequence, Details of any restriction [of randomization] 9. Method used to implement the random allocation sequence 10. Who generated the allocation sequence, who enrolled participants. and who assigned participants to their groups 11. Whether or not participants, those administering the interventions, and those assessing the outcomes were blinded to group assignment. If done, how the success of blinding was evaluated 12. Statistical methods used to compare groups for primary outcome(s), Methods for additional analyses, such as subgroup analyses and adjusted analyses 13. Flow of participants through each stage (a diagram is strongly recommended) Specifically, for each group report the numbers of participants randomly assigned. receiving intended treatment, completing the study protocol. and analyzed for the primary outcome. Results and Conclusion: Randomized Controlled Trial: RCT guided of CONSORT will contribute to do stronger evidence-based medical studies.