• 대한토목학회논문집
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• 제36권5호
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• pp.847-856
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• 2016

최근 우리나라는 고도의 경제 성장과 더불어 급격한 도시화로 인하여 인구, 환경, 주택문제가 발생하고 있고, 특히 교통문제는 심각한 사회 문제로 대두되고 있는 실정이다. 현재까지의 교통정책 방향은 차량소통 중심으로 시행되어 온 것이 현실이다. 이에 본 연구에서는 운전자 관점이 아닌 보행자 관점의 교통정책의 필요성을 부각시키고자 한다. 2015년 전체 교통사고 사망자수(4,621명) 대비 보행 중 사망자수(1,795명) 비율은 38.8%로 보행자 교통사고 해결 방안 수립이 요구되고 있다. 횡단보도는 보행자가 안전하게 횡단할 수 있어야 하지만 현행 횡단보도의 폭원 산정 및 정지선 설치위치에 대한 명확한 기준 없이 도로의 폭을 기준으로 설치되어 있다. 특히 보행량이 많은 대학교나 상업시설 주변 지역은 횡단보도 설계 시 보행자 통행을 고려하지 않고 설계되고 있는 실정이다. 횡단보도 녹색시간 동안 수용할 수 있는 보행자 통행량보다 실제 통행량이 많을 경우, 대기 보행자가 주어진 녹색시간 동안 횡단하지 못하거나 주어진 횡단보도 면적을 벗어난 상태로 무리하게 횡단하여 교통 안전상의 문제가 발생할 수 있다. 이에 본 연구에서는 차량소통 위주의 신호시간 결정, 보행 신호시간 부족, 대로 상에서의 보행자 횡단거리 등 많은 문제점을 내재하고 있는 횡단보도 내 보행자 사고율을 낮추고자 보행자 통행량과 보행속도를 고려한 횡단보도 제원을 산정하고자 한다. 먼저 횡단보도 제원 산정을 위해 횡단보도, 보행자, 정지선에 관한 법규와 기존 연구문헌을 고찰하였다. 기존 횡단보도 제원과 정지선의 문제점을 분석하여 횡단보도 제원 산정을 위한 방법론을 제시하고, 이를 토대로 횡단보도 제원을 산정하였다. 결론적으로 본 연구에서 제시한 횡단보도 제원 및 정지선 개선방안은 해당 교통안전시설물 설치 및 기준 정립 시 기초 자료로 활용 가능할 것으로 기대된다.

• The Korean Journal of Physiology
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• 제2권2호
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• pp.33-43
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• 1968

Histamine, 0.5 mg as histamine base in 4 ml of normal saline solution, was injected into rabbits anesthetized with nembutal and the mean blood pressure was kept in the range of $52{\sim}80\;mmHg$ for over one hour by supplemental additions. Following the injection of the test substances, 300 mg of urea and 200 mg of antipyrine intravenously, serial blood samples were obtained from the femoral artery and the internal jugular vein at $0.5{\sim}3$ minutes interval. The decreasing patterns in the concentrations of arterial and venous blood plasma samples were compared with each other. The ratio of the concentration of brain tissue to that of the final arterial plasma was also studied. By these measures the degrees of penetration of the test substances in the brain in the control and in the histamine treated rabbits were observed. The concentrations of antipyrine and urea in the arterial blood plasma were decreasing exponentially with respect to the time elapsed. The venous concentrations were anticipated to increase initially and to cross the arterial concentration curve in the point of equlibrium between the plasma and the tissue. On the contrary to the expectation venous concentration also revealed the decreasing tendency similar to that of arterial plasma. The similarity between these two curves, arterial and venous, would be atributable to the fact that the cerebral blood flow rate was large enough and the rising phase in the venous concentration curve was instantly over before serial blood samples were taken. Inspite of some similarity in the decreasing tedency in both concentration curves there were appreciable discrepancies between the arterial and venous plasma which would reflect the situation far from the equlibria among several compartments in the brain. Changes in plasma potassium levels caused by the injection of histamine or bleeding were observed, too. Using 8 rabbits as the control and 12 rabbits for the histamine treated group following results were obtained: 1. Both of the concentration curves, arterial and venous, declined rapidly at_first and slowly later on and approached same equilibrium concentration with the passage of time after a single injection. The time at which attained the same concentration was $2.0{\pm}0.54\;min.$ in the control and $4.3{\pm}1.92\;min.$ in the histamine treated group with respect to antipyrine. On the other hand in the case of urea they were $2.4{\pm}0.59\;min.$ in the control and $4.4{\pm}1.31\;min.$ in the histamine group, respectively. In the histamine treated group enlarged spaces for distribution of test substances were postulated. 2. The concentration of antipyrine in the brain tissue water revealed no significant differences between the control and experimental groups, showing $212{\pm}40.2\;mg/l$ in the control and $206{\pm}64.1\;mg/l$ in the histamine treated group. On the other hand urea revealed higher value in the histamine treated group than in the control, showing an enhanced penetration of urea into the tissue after injection of histamine. Urea concentration in the brain water was $32.3{\pm}3.36\;mg%$ in the control and $39.2{\pm}4.25\;mg%$ in the histamine treated group. 3. The distribution ratio of antipyrine in the brain tissue was very close to unity in the histamine treated animals as well as in the control. 4. The average of the distribution ratio of urea in the control animals was 0.77 and it showed the presence of blood-brain barrier with regard to urea. However in the histamine treated animals the distribution ratios climbed up to 0.86 and they were closer to unity than in the control animals. Out of 12 cases 5 were greater than 0.9 and 8 exceeded 0.85. It appeared that histamine enhanced the penetration of urea through the barrier. 5. Histamine injection and or hemorrhage caused an elevation of the concentration of potassium in plasma. In the event that histamine and hemorrhage were applied together the elevation of potassium exceed the elevation seen at the histamine alone. There was no evidence that the leakage of potassium from the brain tissue was dominant in comparison with the general leakage from the whole body.

• 한국항해항만학회지
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• 제37권6호
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• pp.637-645
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• 2013

마산만은 반폐쇄성 해역으로, 느린 유속과 육상오염물질의 하천부하 등으로 인해 심각한 수질문제를 가지고 있으며, 동시에 폭풍해일에 취약한 입지적 특성을 나타내고 있다. 이 중 폭풍해일 저감대책으로 제시된 재해방지시설을 운용함과 동시에 이를 마산만 내측 수질개선에 활용하는 방안을 모색하였다. 즉, 재해방지시설을 가동하여 마산만 내측과 외측의 수위조건이 다를 때 발생하는 수두차를 이용하여 만 내 외의 해수를 교환하였다. 재해방지시설의 위치를 기존 만 입구부, 마창대교 인근, 그리고 돝섬 인근으로 가정하였으며, 선박운항 횟수와 연간조위를 분석하여 통항빈도가 가장 낮은 새벽시간(01~05) 및 수두차가 가장 큰 대조기에 운용된다고 가정하였다. 또한, 재해방지시설과 함께 약 10km 길이의 유출 입 관로를 통한 내 외해수의 해수교환 촉진을 위한 추가 실험안을 구성하였다. 수치모의 결과, 현재상태의 경우 마산만 전체 해수교환율은 38.62%을 나타냈으며, 모든 실험안에서 마산만 내 모든 구역에서 꾸준한 증가 추세를 보이고 있다. 이에 반해, 마산만 입구부와 비교한 마산만 내측의 해수교환율은 매우 낮게 나타나 반폐쇄성 내만해역의 특성을 잘 재현하는 것으로 판단된다. 재해방지시설과 관로를 이용한 실험안을 분석한 결과, 현재상태와 비교하여 재해방지시설을 운용한 경우 해수교환율이 높고, 그 운용빈도가 많아질수록 더 많은 순환이 이루어지는 것으로 나타났다. 또한, 재해방지시설에 의해 발생된 수두차를 이용하여 관로를 통해 해수를 유입 혹은 유출한 경우 마산만 가장 내측의 수질이 개선되는 것으로 나타났다. 재해방지시설의 위치는 마창대교 남측과 비교하여 마산만 입구와 돝섬에 위치한 경우 해수교환 효과가 더 좋게 나타났다. 한편 마산만 전체영역에 대한 해수교환율은 만 입구에 재해방지시설이 위치한 경우가 돝섬에 위치한 경우보다 높지만, 마산만 내측을 포함한 해수교환율은 반대로 돝섬에 위치한 경우가 더 높게 나타났다.

• 혜화의학회지
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• 제8권2호
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• pp.211-243
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• 2000

This study was performed to investigate the cause, symptom, treatment, medicine of Wei symptom through the literature of oriental and western medicine. The results obtained were as follows: 1. Wei symptom is the symptom that reveals muscle relaxation without contraction and muscle relaxation occures in the lower limb or upper limb, in severe case, leads to death. 2. Since the pathology and etiology of Wei symptom was first described as "pe-yeol-yeop-cho"(肺熱葉焦) in Hung Ti Nei Ching(黃帝內經), for generations most doctors had have accepted it. but after Dan Ge(丹溪), it had been classified into seven causes, damp-heat(濕熱), phlegm-damp(濕痰), deficiency of qi(氣虛), deficiency of blood(血虛), deficiency of yin(陰處), stagnant blood(死血), stagnant food(食積). Chang Gyeng Ag(張景岳) added the cause of deficiency of source qi(元氣). 3. The concept of "To treat Yangming, most of all"(獨治陽明) was emphasized in the treatment of Wei symptom and contains nourishment of middle warmer energy(補益中氣), clearance of yangming-damp-heat(淸化陽明濕熱). 4. Since Nei-ching era(內經時代), Wei and Bi symptom(痺症) is differenciated according to the existence of pain. After Ming era(明代) appeared theory of co-existence of Wei symptom and pain or numbness but they were accepted as a sign of Wei symptom caused by the pathological factor phelgm(痰), damp(濕), stagnancy(瘀). 5. In the western medical point of view, Wei symptom is like paraplegia, or tetraplegia. and according to the causative disease, it is accompanied by dysesthesia, paresthsia, pain. thus it is more recommended to use hwal-hyel-hwa-ae(活血化瘀) method considering damp-heat(濕熱), qi deficiency of spleen and stornach(脾胃氣虛) as pathological basis than to simply differenciate Wei and Bi symptom according to the existence of pain. 6. The cause of Gullian-Barre syndrome(GBS) is consist of two factors, internal and external. Internal factors include asthenia of spleen and stomach, and of liver and kidney. External factors include summur-damp(暑濕), damp-heat(濕熱), cold-damp(寒濕) and on the basis of "classification and treatment according to the symptom of Zang-Fu"(臟腑辨證論治), the cause of GBS is classified into injury of body fluid by lung heat(肺熱傷津), infiltration of damp-heat(濕熱浸淫), asthenia of spleen and kidney(脾腎兩虛), asthenia of spleen and stomach(脾胃虛弱), asthenia of liver and kidney (肝腎兩虛). 7. The cause of GBS is divided by according to the disease developing stage: Early stage include dryness-heat(燥熱), damp(濕邪), phlegm(痰濁), stagnant blood(瘀血), and major treatment is reducing of excess(瀉實). Late stage include deficiency of essence(精虛), deficiency with excess(虛中挾實), and essencial deficiency of liver and kidney(肝腎精不足) is major point of treatment. 8. Following is the herbal medicine of GBS according to the stage. In case of summur-damp(暑濕), chung-seu-iki-tang(淸暑益氣湯) is used which helps cooling and drainage of summer-damp(淸利暑濕), reinforcement of qi and passage of collateral channels(補氣通絡). In case of damp-heat, used kun-bo-hwan(健步丸), In case of cool-damp(寒濕), used 'Mahwang-buja-sesin-tang with sam-chul-tang'(麻黃附子細辛湯合蓼朮湯). In case of asthenia of spleen and kidney, used 'Sam-lyeng-baik-chul san'(蔘笭白朮散), In case of asthenia of liver and kidney, used 'Hojam-hwan'(虎潛丸). 9. Following is the herbal medicine of GBS according to the "classification and treatment according to the symptom of Zang-Fu"(臟腑辨證論治). In the case of injury of body fluid by lung heat(肺熱傷津), 'Chung-jo-gu-pae-tang'(淸燥救肺湯) is used. In case of 'infiltration of damp-heat'(濕熱浸淫), us-ed 'Yi-myo-hwan'(二妙丸), In case of 'infiltration of cool-damp'(寒濕浸淫), us-ed 'Yui-lyung-tang', In case of asthenia of spleen, used 'Sam-lyung-bak-chul-san'. In case of yin-deficiency of liver and kidney(肝腎陰虛), used 'Ji-bak-ji-hwang-hwan'(知柏地黃丸), or 'Ho-jam-hwan'(虎潛丸). 10. Cervical spondylosis with myelopathy is occuered by compression or ischemia of spinal cord. 11. The cause of cervical spondylosis with myelopathy consist of 'flow disturbance of the channel points of tai-yang'(太陽經兪不利), 'stagnancy of cool-damp'(寒濕凝聚), 'congestion of phlegm-damp stagnant substances'(痰濕膠阻), 'impairment of liver and kidney'(肝腎虛損). 12. In treatment of cervical spondylosis with myelopathy, are used 'Ge-ji-ga-gal-geun-tang-gagam'(桂枝加葛根湯加減), 'So-hwal-lack-dan-hap-do-hong-eum-gagam(小活絡丹合桃紅飮加減), 'Sin-tong-chuck-ue-tang-gagam(身痛逐瘀湯加減), 'Do-dam-tang-hap-sa-mul-tang-gagam'(導痰湯合四物湯加減), 'Ik-sin-yang-hyel-guen-bo-tang'(益腎養血健步湯加減), 'Nok-gakyo-hwan-gagam'(鹿角膠丸加減). 13. The cause of muscle dystropy is related with 'the impairement of vital qi'(元氣損傷), and 'impairement of five Zang organ'(五臟敗傷). Symptoms and signs are classified into asthenia of spleen and stomach, deficiency with excess, 'deficiency of liver and kidney'(肝腎不足) infiltration of damp-heat, 'deficiency of qi and blood'(氣血兩虛), 'yang deficiency of spleen and kidney'(脾腎陽虛). 14. 'Bo-jung-ik-gi-tang'(補中益氣湯), 'Gum-gang-hwan'(金剛丸), 'Yi-gong-san-hap-sam-myo-hwan'(異功散合三妙丸), 'Ja-hyel-yang-gun-tang'(滋血養筋湯), 'Ho-jam-hwan'(虎潛丸) are used for muscle dystropy. 15. The causes of myasthenia gravis are classified into 'insufficiency of middle warmer energy'(中氣不足), 'deficiency of qi and yin of spleen and kidney'(脾腎兩處), 'asthenia of qi of spleen'(脾氣虛弱), 'deficiency of qi and blood'(氣血兩虛), 'yang deficiency of spleen and kidney'(脾腎陽虛). 16. 'Bo-jung-ik-gi-tang-gagam'(補中益氣湯加減), 'Sa-gun-ja-tang-hap-gi-guk-yang-hyel-tang'(四君子湯合杞菊地黃湯), 'Sa-gun-ja-tang-hap-u-gyi-eum-gagam'(四君子湯合右歸飮加減), 'Pal-jin-tang'(八珍湯), 'U-gyi-eum'(右歸飮) are used for myasthenia gravis.