• Title/Summary/Keyword: Fixed Effects

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Numerical Study on the Thermal NOx Reduction by Addition of Moisture in LNG Flame (가습 공기의 LNG 화염 Thermal NOx 저감의 수치 해석적 연구)

  • Shin, Mi-Soo;Park, Mi-Sun;Jang, Dong-Soon
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.12
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    • pp.837-842
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    • 2014
  • A computer program is developed for the prediction of NO generation by the addition of water moisture and water electrolysis gas in LNG-fired turbulent reacting flow. This study is the first part to deal with the moisture effect on NO generation. In this study, parametric investigation has been made in order to see the reduction of thermal NO as a function of amount of moisture content in a LNG-fired flame together with the swirl and radiation effect. First of all, calculation results show that the flame separation together with the NO concentration separation are observed by the typical flow separation due to strong swirl flow. With a fixed amount of air, the increased amount of water moisture from 0 to 10% by 2% interval shows the decrease of NO concentration and flame temperature at exit are from $973^{\circ}C$ and 139 ppm to $852^{\circ}C$ and 71 ppm. The radiation effects on the generation on NO appears more dominant than swirl strength over the range employed in this study. However, for the strong swirl flow employed in this study, the flow separation cause the relatively high NO concentration observed near exit after peak concentration in the front side of the combustor.

Development of Antifreeze Concentration Control device for Solar Heat Energy System (태양열에너지 시스템용 부동액 농도 제어 장치의 개발)

  • Seo, Choong-Kil;Won, Joung Wun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.4
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    • pp.1-7
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    • 2018
  • The gases emitted from internal combustion engines using fossil fuels are causing many social problems, such as environmental pollution, global warming, and adverse health effects on the human body. In recent years, the demand for renewable energy has increased, and government policy support and research and development are also active. In the collecting part of a solar energy system, which is widely used at home, propylene glycol (PG) (anti-freeze), as a heating medium, is mixed with water at a fixed value of 50%, and the heat is transferred to the collecting part at subzero temperatures. On the other hand, when leakage occurs in the heat medium in the heat collecting part, supplemental water is supplied to the solar heat collecting part due to the characteristics of the solar heat system, so that the concentration of antifreeze in the replenishing water becomes low. As a result, the temperature of the solar heat collecting part is lowered resulting in a frost wave, which causes economic damage. The purpose of this study was to develop a device capable of controlling the antifreeze concentration automatically in response to a temperature drop to prevent freezing of the heat collecting part generated in the solar energy system. The electrical conductivity of the H2O component was larger than that of PG, and the resistance increased with decreasing temperature. The PG concentration control values of 40, 50, and 60% should be controlled through calibration with a PG concentration of 39.6, 50.7, and 60.1%.

Effect of aging on Leydig cells of Sprague Dawley rats (흰쥐에서 고환 간질세포에 미치는 노화의 영향)

  • Kim, In-Shik;Tae, Hun-Jin;Li, Li-Guang;Park, Young-Jae;Kang, Hyung-Sub;Park, Sang-Youel;Park, Soo-Hyun;Park, Young-Seok;Lee, Young-Hoon;Ahn, Dong-Choon;Choi, Eun-Young;Yang, Hong-Hyun
    • Korean Journal of Veterinary Research
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    • v.43 no.4
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    • pp.541-549
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    • 2003
  • The present study investigated the effects of aging on Leydig cells of Sprague Dawley rats. Rats of 3, 6, 12 and 18 months of age were used. Testes of rat were fixed by whole body perfusion using a fixative containing 2.5% glutaraldehyde in cacodylate buffer, processed and embedded in epon-araldite. Using $1{\mu}m$ sections stained with methylene blue, qualitative and quantitative morphological studies were performed. Testis incubations were used to determine luteinizing hormone (LH; 100 ng/ml) stimulated testosterone secretory capacity per testis in vitro. Testosterone levels in the incubation medium, and testosterone and luteinizing hormone levels in serum of these four groups of rats were determined by radioimmunoassay. Morphological studies revealed that Leydig cells were more abundant in the testis interstitium at 6, 12 and 18 months when compared with 3 months. The volumes of Leydig cells per testis was significantly higher, at 6, 12 and 18 months of age than those at 3 months. The number of Leydig cells per testis was doubled at 6, 12 and 18 months of age compared with 3 months. The average volume of a Leydig cell was not significantly different between 3 and 6 months of age, however, at 12 and 18 months a significantly lower value was observed. LH-stimulated testosterone production per testis in vitro was reduced by 45% at 6 months of age compared with 3 months; a further significant reduction was observed at 12 and 18 months. Serum testosterone and LH levels were not significantly different between 3 and 6 months of age but at 12 and 18 months a significantly lower value was observed in both groups for these hormones. These results showed that signs of aging are apparent in Leydig cells of Sprague Dawley rats at 12 months of age.

Changes of the liver volume and the Child-Pugh score after high dose hypofractionated radiotherapy in patients with small hepatocellular carcinoma

  • Kim, Young Il;Park, Hee Chul;Lim, Do Hoon;Park, Hyo Jung;Kang, Sang Won;Park, Su Yeon;Kim, Jin Sung;Han, Youngyih;Paik, Seung Woon
    • Radiation Oncology Journal
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    • v.30 no.4
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    • pp.189-196
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    • 2012
  • Purpose: To investigate the safety of high dose hypofractionated radiotherapy (RT) in patients with small hepatocellular carcinoma (HCC) in terms of liver volumetric changes and clinical liver function. Materials and Methods: We retrospectively reviewed 16 patients with small HCC who were treated with high dose hypofractionated RT between 2006 and 2009. The serial changes of the liver volumetric parameter were analyzed from pre-RT and follow-up (FU) computed tomography (CT) scans. We estimated linear time trends of whole liver volume using a linear mixed model. The serial changes of the Child-Pugh (CP) scores were also analyzed in relation to the volumetric changes. Results: Mean pre-RT volume of entire liver was 1,192.2 mL (range, 502.6 to 1,310.2 mL) and mean clinical target volume was 14.7 mL (range, 1.56 to 70.07 mL). Fourteen (87.5%) patients had 4 FU CT sets and 2 (12.5%) patients had 3 FU CT sets. Mean interval between FU CT acquisition was 2.5 months. After considering age, gender and the irradiated liver volume as a fixed effects, the mixed model analysis confirmed that the change in liver volume is not significant throughout the time course of FU periods. Majority of patients had a CP score change less than 2 except in 1 patient who had CP score change more than 3. Conclusion: The high dose hypofractionated RT for small HCC is relatively safe and feasible in terms of liver volumetric changes and clinical liver function.

Effects of Mixed Casting Solvents on Morphology and Characteristics of Sulfonated Poly(aryl ether sulfone) Membranes for DMFC Applications (직접 메탄올 연료전지용 술폰화 폴리아릴에테르술폰 전해질 막의 혼합 캐스팅 용매에 따른 형태 및 특성)

  • Hong, Young-Taik;Park, Ji-Young;Choi, Jun-Kyu;Choi, Kuk-Jong;Hwang, Taek-Sung;Kim, Hyung-Joong
    • Membrane Journal
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    • v.18 no.4
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    • pp.282-293
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    • 2008
  • Partially sulfonated poly(aryl ether sulfone) membranes were prepared from the sulfonated sulfone monomer, which was synthesized by a nucleophilic substitution, non-sulfonated monomers and potassium carbonate by a direct polymerization method and a subsequent solution casting technique with mixed solvents of N-methyl-2-pyrrolidone (NMP) and dimethylacetamide (DMAc). To investigate the effect of mixed solvent, the volume ratios of NMP and DMAc were varied in the range of $0{\sim}100%$ and the degrees of sulfonation of the copolymers were fixed as 50%. The surface properties of the resulting membranes were examined by scanning electron microscope (SEM) and atomic force microscope (AFM), and a comparative study of the morphology changes and the physicochemical properties such as proton conductivity and methanol permeability was achieved. It was found that proton conductivities depend on the volume ratio of NMP-DMAc mixed solvents, and the proton conductivity determined at the condition of $25^{\circ}C$ and 100% relative humidity was $1.38{\times}10^{-1}\;S/cm$ for the membrane prepared in the 50:50 v/v-% of NMP : DMAc mixed solvent.

Hypoxia Induced High Expression of Thioredoxin Interacting Protein (TXNIP) in Non-small Cell Lung Cancer and its Prognostic Effect

  • Li, Yan;Miao, Li-Yun;Xiao, Yong-Long;Huang, Mei;Yu, Min;Meng, Kui;Cai, Hou-Rong
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.7
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    • pp.2953-2958
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    • 2015
  • Although associations between thioredoxin interacting protein (TXNIP) and cancers have been recognized, the effects of TXNIP on non-small cell lung cancer (NSCLC) prognosis remained to be determined in detail. In addition, while hypoxia is a key characteristic of tumor cell growth microenvironment, the effect of hypoxia on TXNIP expression is controversial. In this study, formaldehyde fixed and paraffin embedded (FFPE) samples of 70 NSCLC patients who underwent resection between January 2010 and December 2011 were obtained. Evaluation of TXNIP and hypoxia inducible factor-$1{\alpha}$ ($HIF-1{\alpha}$) protein expression in FFPE samples was made by immunohistochemistry. By Kaplan-Meier method, patients with high TXNIP expression demonstrated a significantly shorter progression free survival (PFS) compared with those with low TXNIP expression (18.0 months, 95%CI: 11.7, 24.3 versus 23.0 months, 95%CI: 17.6, 28.4, P=0.02). High TXNIP expression level was also identified as an independent prognostic factor by Cox regression analysis (adjusted hazard ratio: 2.46; 95%CI: 1.08, 5.56; P=0.03). Furthermore, TXNIP expression was found to be significantly correlated with $HIF-1{\alpha}$ expression (Spearman correlation=0.67, P=0.000). To further confirm correlations, we established a tumor cell hypoxic culture model. Expression of TXNIP was up-regulated in all three NSCLC cell lines (A549, SPC-A1, and H1299) under hypoxic conditions. This study suggests that hypoxia induces increased TXNIP expression in NSCLC and high TXNIP expression could be a poor prognostic marker.

Development of Road Surface Management System using Digital Imagery (수치영상을 이용한 도로 노면관리시스템 개발)

  • Seo, Dong-Ju
    • Journal of the Korean Association of Geographic Information Studies
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    • v.10 no.1
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    • pp.35-46
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    • 2007
  • In the study digital imagery was used to examine asphalt concrete pavements. With digitally mastered-image information that was filmed with a video camera fixed on a car travelling on road at a consistent speed, a road surface management system that can gain road surface information (Crack, Rutting, IRI) was developed using an object-oriented language "Delphi". This system was designed to improve visualized effects by animations and graphs. After analyzing the accuracy of 3-D coordinates of road surfaces that were decided using multiple image orientation and bundle adjustment method, the average of standard errors turned out to be 0.0427m in the X direction, 0.0527m in the Y direction and 0.1539m in the Z direction. As a result, it was found to be good enough to be put to practical use for maps drawn on scales below 1/1000, which are currently producted and used in our country, and GIS data. According to the analysis of the accuracy in crack width on 12 spots using a digital video camera, the standard error was found to be ${\pm}0.256mm$, which is considered as high precision. In order to get information on rutting, the physically measured cross sections of 4 spots were compared with cross sections generated from digital images. Even though a maximum error turned out to be 10.88mm, its practicality is found in work efficiency.

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A Study on Inelastic Lateral-Torsional Buckling of Stepped I-Beams Subjected to Pure Bending (균일모멘트를 받는 계단식 I형보의 비탄성 횡-비틀림 좌굴에 관한 연구)

  • Kim, Jong Min;Kim, Seung Jun;Park, Jong Sup;Kang, Young Jong
    • Journal of Korean Society of Steel Construction
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    • v.20 no.2
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    • pp.237-246
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    • 2008
  • The cross-sections of continuous multi-span beams sometimes suddenly increase, or become stepped, at the interior supports of continuous beams to resist high negative moments. The three-dimensional finite-element program ABAQUS (2006) was used to analytically investigate the inelastic lateral-torsional buckling behavior of stepped beams subjected to pure bending moment and resulted in the development of design equations. The flanges of the smaller cross-section were fixed at 30.48 by 2.54 cm, whereas the width and/or thickness of the flanges of the larger cross-section varied. The web thickness and height of beam was kept at 1.65 cm and 88.9 cm, respectively. The ratios of the flange thickness, flange width, and stepped length of beams are considered analytical parameters. Two groups of 27 cases and 35 cases, respectively, were analyzed for double and single stepped beams. The combined effects of residual stresses and geometrical imperfection on inelastic lateral-torsional buckling of beams are considered. First, the distributions of residual stress of the cross-section is same as shown in Pi, etc (1995), and the initial geometric imperfection of the beam is set by central displacement equal to 0.1% of the unbraced length of beam. The new proposed equations definitely improve current design methods for the inelastic LTB problem and increase efficiency in building and bridge design. The proposed solutions can be easily used to develop new design equation for inelastic LTB resistance of stepped beams subjected to general loading condition such as a concentrated load, a series of concentrated loads or uniformly distributed load.

The effect of ceramic thickness and number of firings on the color of a zirconium oxide based all ceramic system fabricated using CAD/CAM technology

  • Bachhav, Vinay Chila;Aras, Meena Ajay
    • The Journal of Advanced Prosthodontics
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    • v.3 no.2
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    • pp.57-62
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    • 2011
  • MATERIALS AND METHODS. Ceramics have a long history in fixed prosthodontics for achieving optimal esthetics and various materials have been used to improve ceramic core strength. However, there is a lack of information on how color is affected by fabrication procedure. The purpose of this study was to evaluate the effects of various dentin ceramic thicknesses and repeated firings on the color of zirconium oxide all-ceramic system (LavaTM) fabricated using CAD/CAM technology. MATERIALS AND METHODS. Thirty disc-shaped cores, 12 mm in diameter with a 1 mm thickness were fabricated from zirconium oxide based all ceramic systems ($Lava^{TM}$, 3M ESPE, St Paul, MN, USA) and divided into three groups (n = 10) according to veneering with dentin ceramic thicknesses: as 0.5, 1, or 1.5 mm. Repeated firings (3, 5, 7, or 9) were performed, and the color of the specimens was compared with the color after the initial firing. Color differences among ceramic specimens were measured using a spectrophotometer (VITA Easyshade, VITA Zahnfabrik, Bad $S{\ddot{a}}ckingen$, Germany) and data were expressed in CIELAB system coordinates. A repeated measures ANOVA and Bonferroni post hoc test were used to analyze the data (n = 10, ${\alpha}=.05$). RESULTS. $L^{\ast}a^{\ast}b^{\ast}$ values of the ceramic systems were affected by the number of firings (3, 5, 7, or 9 firings) (P<.001) and ceramic thickness (0.5, 1, or 1.5 mm) (P<.001). Significant interactions were present in $L^{\ast}a^{\ast}b^{\ast}$ values between the number of firings and ceramic thickness (P<.001). An increase in number of firings resulted in significant increase in $L^{\ast}$ values for both 0.5 mm and 1.5 mm thicknesses (P<.01, P=.013); however it decreased for 1 mm thickness (P<.01). The $a^{\ast}$ values increased for 1 mm and 1.5 mm thicknesses (P<.01), while it decreased for 0.5 mm specimens. The $b^{\ast}$ values increased significantly for all thicknesses (P<.01, P=.022). As the dentin ceramic thickness increased, significant reductions in $L^{\ast}$ values (P<.01) were recorded. There were significant increases in both $a^{\ast}$ and $b^{\ast}$ values (P<.01) as the dentin ceramic thickness increased. CONCLUSION. The number of firings and dentin ceramic thickness have a definite effect on the final color of all ceramic system tested. The mean ${\Delta}E$ value increased as the dentin ceramic thicknesses increased for zirconium-oxide based all ceramic specimens tested. However, the mean ${\Delta}E$ values were less than 3.7${\Delta}E$ units which is rated as a match in the oral environment.

The Point Load Index of the Daegu Shale and its Relation to the Uniaxial Compressive Strength (대구지역 셰일의 점재하지수 특성 및 일축압축강도와의 상관성)

  • Lee, Younghuy;Youn, Chanho
    • Journal of the Korean GEO-environmental Society
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    • v.10 no.3
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    • pp.37-45
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    • 2009
  • The experimental study was carried out to evaluate the characteristics of the point load index and the uniaxial compressive strength of inherently anisotropic shale in the laboratory. In the testing program the effects of size and the shape on the point load index were investigated both in the axial and diametral direction. In general, the point load index of the shale was constant when the length/diameter (L/D) ratio of the specimen is greater than 1.0 in the diametral direction. The point load index in axial direction shows slight decrease as the L/D ratio is increased and the corner breakage was observed when L/D ratio is greater than unity. The minimum point load index was observed in the bedding angle of $\beta=15^{\circ}{\sim}30^{\circ}$ in the axial point load tests and of $\beta=30^{\circ}$ in the uniaxial compression tests. The relationship between the point load index and the uniaxial compressive strength was linear to ${\sigma}_c=25.0 I_{s(50)}$ for the specimen with the bedding plane angle, $\beta$ at the range of $0^{\circ}{\sim}90^{\circ}$. On the other hand, this relationship was appeared linear to ${\sigma}_c=14.4 I_{s(50)}$ when the bedding angle, $\beta$ is fixed to 90${^{\circ}}$ and this correlation is much different from ${\sigma}c=22 I_{s(50)}, which is generally applied to the rock specimen with no bedding plane in ISRM (1985). The anisotropic strength with different $\beta$ angle shows the shoulder type and this can be suitably modelled by the corrected Ramamurthy'(1993)s equation with the index value of 'n' equal to 3.0.

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