• Journal of Yeungnam Medical Science
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• 제11권2호
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• pp.381-387
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• 1994

저자틀은 53세 여자로써 연하곤란, 철 결핍성 빈혈, 구각순증, 설염, 스푼형 조갑과 경부식도 막양구조를 특징으로 하고, 내시경적 풍선확장술에 의한 막양구조의 제거와 경구 철제 투여 후 현저한 증상의 호전을 보인 전형적인 Plummer-Vinson 증후군 환자를 경험하였다. 병력상 연하곤란이 나타나기 전부터 빈혈이 발견되었고, 철제 투여 후 피부와 점막의 병변도 호전된 점등을 고려해 볼 때 철 결핍이 본 질환의 발생에 중요한 역할을 한 것으로 추측할 수 있었다.

• 한국안광학회지
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• 제10권2호
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• pp.139-144
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• 2005

본 연구의 목적은 한국 여자 대학생들의 안구돌출과 검열폭의 정상 값 분석을 위해 수행한 것이다. 평균 측정값은 18세에서 21세 사이의 118명을 대상으로 검사하였다. 18세부터 21세까지 평균검열의 폭은 $6.967{\pm}1.599mm$, $7.172{\pm}1.502mm$, $8.015{\pm}1.44mm$, $7.1{\pm}1.224mm$로 나타났다. 한편 18세부터 21세까지 평균 안구돌출 값은 $12.50{\pm}2.33mm$, $12.343{\pm}2.634mm$, $12.773{\pm}1.974mm$, $13.036{\pm}2.23mm$로 나타났다. 연령의 증가에 따라 검열의 폭과 안구 돌출 값은 약간 증가하였으나, 21세에서 검열의 폭은 다소 감소함이 나타났다. 그러나 오른 눈과 왼 눈에서의 통계적인 유의성은 없었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권6호
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• pp.681-683
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• 2007

Kabuki(Niikawa-Kuroki) syndrome was first reported by Niikawa et al(1981). The faces of the patients are similar to the make-up of traditional Japanese Kabuki actors: long palpebral fissures, an ectropium of the lateral third of the eyelids, and arching eyebrows with sparse lateral halves. Craniofacial findings include a depressed nasal tip, short nasal septum, large and prominent ears, and micrognathia. Other main features area mild to moderate mental deficiency, short stature, skeletal and dermatoglyphic abnormalities, including prominent finger tip pads. Oral anomalies are common in KS(over 60%) and include abnormal dentition, widely spaced teeth, cleft palate or lip, high vault of palate, hypodontia, conical incisors, screw driver-shaped incisors and ectopic upper 6-year molars. The increased occurrence of cleft lip and palate or the development of a high vault of palate has been described by a number of authors. This condition is believed to be common in Japan, but has been reported from other parts of the world. The objective of this presentation is to report a case of this syndrome in six-year-old girl, with characteristic findings.

• 대한기계학회논문집A
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• 제25권3호
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• pp.510-519
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• 2001

The tensile and fracture toughness tests have been conducted to investigate the degradations of mechanical properties induced mainly by neutron irradiations in Zr-2.5Nb CANDU pressure tube materials operated in Wolsung Unit-1. the tests were performed at room, 150, 200, 250, 300 $\^{C}$ for the irradiated and unirradiated specimens in hot cell. The specimens were directly machined from the tube retaining original curvature using specially designed electric discharge machine(EDM). From the tensile tests of the irradiated specimens, it was found that tensile strength was increased and total elongation was decreased compared to those of the unirradiated ones. The active voltages in the fracture toughness tests for the irradiated showed the discontinuous abrupt increases caused by crack jumping in lower temperature. In the crack resistance curves we found the stable crack growth in the unirradiated, whereas the unstable and three crack growth stages in the irradiated specimens due to the accumulated irradiation defects. The various fracture characteristic values in the irradiated are remarkably lower than those of the unirradiated. Through the fractography, we found in the irradiated that smaller dimple and shorter fissures than the unirradiated, and that the fractured surface had three regions that were flat, transition and slant/shear area. These can explain the difference in the crack growth characteristic values of the irradiated and the unirradiated ones.

• Archives of Plastic Surgery
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• 제40권6호
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• pp.766-772
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• 2013

Background Hypospadias is the most common congenital malformation of the male urinary tract, wherein the urethral opening is located proximal to the normal site. Tubularized incised-plate urethroplasty reconstruction, and its efficacy, remains controversial due to the high recurrence rate. This study aimed to evaluate the results of dartos fascia-reinforced flap surgery in hypospadias patients with previous operative complications. Methods Nine patients (mean age, 12 years) who had previous one- or two-stage repair with TIP urethroplasty and suffered from urethrocutaneous fistulas or fissures as complications, underwent dartos fascia-reinforced flap surgery in our clinic between January 2010 and December 2012. The mean postoperative follow-up period was 6 months. Results Among the 9 patients, 7 had complete correction. In all the patients, the maximum uroflow angle was > $45^{\circ}$. No patient complained of an unnatural urinating position. The patients and parents gave very high satisfaction scores (4.7 points) with regard to the appearance of the outer genitalia. Conclusion The dartos fascia-reinforced flap could be a useful and reliable option for complications of hypospadias repair or fissure with the prepuce preserved, given that histological aspects vary and that the possibility of recurrence in the glanular region is high.

• 대한수의학회지
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• 제34권4호
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• pp.787-799
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• 1994

To elucidate morphologic lesion of porcine exudative epidermitis which is occurred sporadically in Korea, Staphylococcus hyicus subsp. hyicus isolated from the naturally affected pigs was inoculated to suckling pigs. The infected piglets were observed grossly and histopathologically. Although affected piglets were taking acute, subacute, or chronic course, some piglets suffered from chronic disease showed poor prognosis and marked growth depression. Affected peglets had erythematous skin on the face, ear, and abdomen and these localized lesions appear as brownish spots of exudative epidermitis and fromed crust in the early stage. But, after this stage, the skin were covered by viscous greasy exudate and formed blackish brown crust and appeared fissures and hypertrophy. Grossly, there has been hemorrhage with the removal of crust-like materials of epidermis and edematous subcutis. The superficial lymph nodes were edematous and swollen or congested and hemorrhagic. Some piglets had swollen ureters, cysts in the renal cortex, or polyarthritis. A few cases had mild edematous swelling of kidney, intestinal catarrh and congestion of brain. Microscopically, skin lesions had detachment of keralinized layer and parakeratosis of epidermis, hydropic degeneration of epidermal cell, and retrogressive degeneration of hair root sheath. Dermis had edema, and infiltration of neutrophils and mononuclear cells. As the disease was proceeded, there was marked perivasculitis with lots of mononuclear inflammatory cells. More chronic lesions formed granuloma-like bodies(nodules) due to more mononuclear, perivascular inflammatory cell infiltration and proliferation of fibroblast. Lots of plasma cells and eosinophils were also present in dermis. Epidermis was hyperplastic by proliferation of basal cells stratum germinativum and epidermal pegs often extended into the dermis. In secondary infection, lots of neutrophils could be seen in epidermis and derms. Kidney had neutrophilic infiltration, necrotic and cystic glomeruli, and dilation of renal tubules and ureters. Purulent arthritis was sometimes observed in joints. Three days old mice administrated Staphylococcus hyicus subsp hyicus subcutaneously before had focal congestion and hemorrhage, necrosis, and subcutaneous edema of the skin. This observation was also seen in the study of mice administrated exfoliatin toxin of Staphylococcus which evoked human staphylococcal scalded skin syndrome.

• 한국지구과학회지
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• 제23권1호
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• pp.97-104
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• 2002

Mulgeum, Yangseong, Maeri and Kimhae iron ore deposits in Gyeongnam Province are hydrothermal skarn type magnetite ore deposits in propylitized andesitic rock near the contact with Cretaceous Masanite. Symmetrical zoned skarns are commonly developed around the magnetite veins. The skarn zones away from the vein are quartz-garnet skarn, epidote skarn and epidote-orthoclase skarn. Oxygen isotope analyses of coexisting minerals from andesitic rock, Masanite and major skarn zones, and of magnetite, hematite and quartz were conducted to provide the information on the formation temperature, the origin and the evolution of the hydrothermal solution forming the iron ore deposits. Becoming more distant from the ore vein, temperatures of skarn zones represent the decreasing tendency, but most ${\delta}^{18}O$ and ${\delta}^{18}O_{H2O}$ values of skarn minerals represent no variation trend, and also the values are relatively low. Judging from all the isotopic data from the ore deposits, the major source of hydrothermal solution altering the skarn zones and precipitating the ore bodies was magmatic water derived from the deep seated Masanite. This high temperature hydrothermal solution rising through the fissures of propylitized andesitic rock was mixed with some meteoric water, and occurred the extensive isotopic exchange with the propylitized andesitic rock, and formed the skarns. During these processes, the temperature and ${\delta}^{18}O_{H2O}$ value of hydrothermal solution were lowered gradually. At the main stage of iron ore precipitation, because all the alteration was already finished, the new rising hydrothermal solution formed only the magnetite ore without oxygen isotopic exchange with the wall rock.

• 한국지반공학회논문집
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• 제20권7호
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• pp.45-55
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• 2004

경화 모래와 같은 단단한 흙에서는 자주 파괴시의 응력이 실내실험을 통해 얻은 전단강도 보다 작을 뿐만 아니라 일반적인 해석방법이 적절하지 못한 경우를 보게된다. 여러 학자들은 이러한 현상이 일어나는 것은 흙속에 있는 균열이나 절리와 같은 불연속이 존재 하기 때문일거라 생각했고, 따라서 파괴역학이 이런 흙에대해서는 더 적절한 해석방법이 될 수도 있다고 생각 해왔다. 그러나 파괴역학의 개념을 도입하기에는 파괴 요소들이 재료의 구성뿐만 아니라 시료 그리고 입자의 크기에 크게 영향을 받기 때문에 어려움이 많이 있다. 본 연구에서는 경화모래의 파괴 특성에 시료와 입자의 크기가 미치는 영향을 기술한다. 실내실험 결과, 시료와 입자의 크기는 경화모래의 파괴 거동에 많은 영향을 미치는 것을 보여준다.

• Korean Chemical Engineering Research
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• 제51권6호
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• pp.780-783
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• 2013

저분자량의 laminarin은 항산화능과 같은 생물학적 물성이 고분자량의 laminarin과 비교하여 증가하였다는 최근의 연구 결과들이 보고되었다. 이러한 저분자화에 따른 laminarin 생물활성의 증가 원인을 밝히고자 본 논문에서는 이온화 방사선 조사를 통하여 얻어진 저분자량 laminarin의 분자구조에 관한 연구를 수행하였다. 15 kDa 크기의 분자량을 갖는 laminarin을 이온화 방사선 조사를 이용하여 13.5, 8.5, 7, 6 kDa 크기의 저분자량 laminarin 시료들을 얻었다. 얻어진 저분자량 laminarin은 고분자량 laminarin에 비하여 낮은 polydispersity 값을 가졌다. 방사선 조사에 의한 저분자화에 따른 laminarin 기능기들의 변화를 확인하기 위하여 Fourier-transform infrared 분석을 수행한 결과, 분자량 감소에 따라서 대부분의 기능기들의 변화는 관찰되지 않았지만, carbonyl group의 증가가 확인되었다. Laminarin 입자의 scanning electron microscopy 분석으로부터 저분자량 laminarin에서 glycosidic 결합의 분해에 의한 입자 균열이 확인되었다. 이러한 결과들은 laminarin과 같은 다당류의 저분자화에 따른 기능성 변화 연구에 활용될 수 있을 것으로 기대된다.

• 한국산학기술학회논문지
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• 제21권9호
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• pp.352-357
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• 2020

본 연구는 선박용 디젤엔진 부품인 축류 단조품을 단조작업에 의하여 제작하는 과정에서 발생하는 품질문제를 해결하기 위하여 수행되었다. 1차, 2차 가열 및 열간 단조를 거쳐 완성된 단조품은 최종 후열처리공정을 거치게 되는데 이 과정에서 발생하는 것으로 알려진 내부 결함문제를 해결하기 위하여 냉각공정을 평가하였다. 자유단조작업을 거쳐 제작된 축류 단조품에는 2차 열간 단조작업 후 냉각과정에서 소재 내부에 존재하고 있던 잔류 수소가 기공이나 미세 균열, 입계, 계면 등으로 확산, 집적됨으로써 균열을 유발하여 내부 결함이 발생하는 것으로 알려져 있으며 실제 작업현장에서 균열발생 사례가 보고되고 있다. 이러한 문제를 해결하기 위하여 수치해석 전용 프로그램인 ANSYS를 사용하여 열전달 수치해석을 수행하였으며, 해석모델은 축류 단조품의 특성상 축대칭요소를 사용하여 구성하였고 단조품 초기 온도 1250 ℃에서 단조작업 완료 후 냉각과정에서 시간이 경과함에 따른 온도변화를 평가하였다. 주어진 4종류의 축류 단조품에 대하여 온도이력을 평가한 결과 단조품 내부에 수소유기균열 발생이 예상되는 250 ℃까지 냉각되는데 소요되는 시간을 알 수 있었으며, 이러한 냉각시간은 추후 열처리 작업의 작업표준으로 적용함으로써 축류 단조품 제작 시품질과 생산성을 높일 수 있다는 것을 알 수 있다.