• 한국환경농학회지
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• 제24권4호
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• pp.334-340
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• 2005

This experiment was conducted to evaluate the nutrient loss and to assess the eutrophication into small stream by intensive rains in the steeped cornfield during cultivation. The crop cultivated was a soiling com (DW5969), and the experimental plots were divided into two parts that were 10 and 18% of slope degrees. The amount of T-N and T-P loss was calculated by analysis of surface run-off water quality, and was investigated the effect of eutrophication to small stream as a part of life cycle assessment (LCA) methodology application. For the surface run-off water quality, EC and T-N values were highest in first runoff event as compared to the other events and maintained the stage state with litter variations at every hour during the runoff period except for EC in the slope 18%. However, T-P concentration has been a transient stage after runoff event of July 27. Total surface run-off ratio was not significantly different with slope degrees, but amount of T-N and T-P losses at 18% of slope were high as $5.96kg\;ha^{-1}\;and\;0.65kg\;ha^{-1}$ as relative to 10% of slope degree, respectively. Furthermore, T-N losses from run-off water in the sloped cornfield 10 and 18% were approximately 9.8 and 12.5% of the N applied as fertilizer when the fertilizer applied at recommended rates after soil test, respectively. For the eutrophication impact to the small stream, it was shown that $PO_4$ equivalence and Eco-indicator value at 18% of slope degree were greater as much $6.11kg\;ha^{-1}$ and 0.81 as compared to the slope angle 10%, respectively. Therefore, it was appeared that each effect of nutrient losses, eutrophication and Eco-indicator value was enhanced according with higher slope degree.

• Investigative Magnetic Resonance Imaging
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• 제1권1호
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• pp.119-124
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• 1997

목적: 뇌종양에서 자기공명 뇌혈류량지도(MR cerebral blood volume map)의 유용성을 평가하고자 하였다. 대상 및 방법: 15예의 두개강내 종괴(다형성 교모세포종 2예, 저등급 교종 3예, 뇌농양 2예, 뇌수막종 3예, 신경세포종 1예, 배아종 1예, 방사선괴사 1예, 전이암 1예) 에서 관류 MR영상을 수술전에 시행하였다. 환자의 평균연령은 42세였고(22-68), 남자 10명, 여자 5명이었다. MR영상기기는 1.5T unit(Signa, GE Medical Systems, Milwaukee, Wisconsin)를 사용하였다. 조영제 주입후 조영제의 일차 통과시 나타나는 자화율을 얻었다. (조영제는 최오의 MR 촬영시작후 10초부터 시작하여, 총량 15cc 의 Gadopentate dimeglumine(Magnevist)를 약 2ml/sec의 속도로 손으로 주입하였다). 각 환자마다 160초 동안 6 slice에서 slice당 80 image씩 총 480 image를 얻었으며 interleaved single shot gradient EPI기법을 사용하였다. 영상변수는 TR 2000ms, TE 50ms, FOV $240{\times}240mm,{\;}matrix{\;}size{\;}128{\times}128$, slice thickness/gap 5/ 2.5mm, flip angle $90^{\circ}$로 하였다. 얻은 영상데이터는 GE workstation으로 전송한 후, 자체적으로 개발한 software에 의해 각 kvoxel마다 시간경과에 따른 신호크기의 로그변화곡선(${\Delta}R2^{*}=-In(S/S_0$)의 적분값을 구하여 국소뇌혈류량(rCBV)영상을 구성하였다. 이의 시각적 해석을 용이하게 하기 위해 정상 뇌백질의 관류정도를 기준으로 하여 상대적인 RGB 색수치로 변환하여, color rCBV map을 얻었다. 관류의 정도와 조영증강정도를 중심으로 관류 MR 영상소견과 조직학적 소견을 관련지어 분석하였다. 결과: 조영증강 T1강조MR영상에서 환상조영증강을 보이는 다형성 교보세포종 2예에서는 변연부 외륜이 고관류를, 중심부의 괴사부위는 저관류로 나타났다. 저등급 교종은 경계가 불분명한 저관류부위로 보였다. 뇌농양 2예는 변연부 외륜이 경도의 고관류를, 중심부는 저관류로 나타났다. 뇌수막종은 미만성의 균일한 중등도 혹은 고도의 고관류로 보였으며, 임파종과 배아종은 경계가 명확한 저관류부위로 나타났다. 신경세포종은 종괴\ulcorner 일부에 중등도 혹은 고도의 고관류부위가 관찰되었고, 전이암은 다수병변중 일부에서 중등도의 고관류를 보였다. 방사선괴사는 저관류부위내에 국소적 고관류부위를 보였다. 결론: 관류 MR영상은 뇌종양의 관류상태를 비교적 잘 반영하며, 조직학적 특성을 예측하는데에 도움을 주 수 있을 것으로 기대된다. 뇌종야에서의 관류MR영상의 분명한 역할을 규명하기 위해서는 앞으로 더 많은 임상적 연구가 필요할 것으로 생각된다.

• Journal of Biosystems Engineering
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• 제6권2호
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• pp.9-19
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• 1982

소형(小型) 디젤엔진의 예연소실(豫燃燒室) 형상(形狀)이 저온시(低溫時)의 시동성(始動性)에 미치는 영향(影響)을 구명(究明)하기 위해 8종(種)의 예연소실(豫燃燒室)과 2종(種)의 실린더헤드를 제작(製作)하여 $2^7$ 요인실험법(要因實驗法)에 의해 1회(回) 조작시(操作時) 최저(最低) 시동가능(始動可能) 온도(溫度), 최대출력(最大出力), 전부하(全負荷)(4/4) 및 과부하(過負荷)(11/10)시(時)의 연료소비율(燃料消費率)을 측정(測定)하여 분석(分析)한 결과(結果)를 요약(要約)하연 다음과 같다. 가. 피스톤 상면(上面)에 대한 주분사구(主噴射口)의 상대각도(相對角度)가 $20^{\circ}$에서 $18^{\circ}$로 감소(減少)하면 최저(最低) 시동가능(始動可能) 온도(溫度)가 약(約) $2.4^{\circ}C$ 낮아졌으며 최대출력(最大出力)은 약(約) 0.3ps 증가(增加)되었다. 나. 실린더헤드 홈 각도(角度)가 $20^{\circ}$에서 $18^{\circ}$로 작아짐에 따라 최저(最低) 시동가능(始動可能) 온도(溫度)가 약(約) $3.3^{\circ}C$ 낮아졌으며, 최대출력(最大出力)은 약(約) 0.3ps 감소(減少)되었다. 다. 예연소실(豫燃燒室) 길이가 17.5mm에서 15.5mm로 짧아지면 최저(最低) 시동가능(始動可能) 온도(溫度)가 $2^{\circ}C$ 낮아졌으며 최대출력(最大出力)은 0.2ps정도(程度) 감소(減少)되었다. 라. 주분사구(主噴射口) 직경(直俓)이 4.8mm에서 4.5mm로 작아지면 최대출력(最大出力)은 0.2ps정도(程度) 증가(增加)했으나, 주분사구(主噴射口) 직경(直俓)만이 변화(變化)에 따른 시동성(始動性)의 차이(差異)는 인정(認定)되지 않았다. 마. 주분사구(主噴射口) 각도(角度)가 $47^{\circ}$이고 실린더헤드 홈 각도(角度)가 $18^{\circ}$일 경우(境遇) 시동가능(始動可能) 온도(溫度)가 가장 낮았으며, 주분사구(主噴射口) 직경(直俓)이 4.5mm이고 예연소실(豫燃燒室) 길이가 17.5mm일 경우(境遇) 최대출력(最大出力)도 가장 높았고, 전부하(全負荷) 및 과부하시(過負荷時)의 연료소비율(燃料消費率)도 가장 낮았다. 바. 실린더 헤드홈 각도(角度)와 주분사구(主噴射口)의 각도(角度)가 각각(各各) 시동성(始動性) 향상(向上)에 가장 큰 영향(影響)을 미쳤으며, 또한 주분사구(主噴射口) 직경(直俓)과 예연소실(豫燃燒室) 길이와의 교호작용(交互作用)이 최대출력(最大出力)에 가장 큰 영향(影響)을 미쳤으므로 이들 요인(要因)에 대한 처리수(處理數)를 늘려 시험(試驗)해 볼 필요성(必要性)이 있는 것으로 사료(思料)된다. 사. 본(本) 실험(實驗)에서 최적조건(最適條件)으로 나타난 시작(試作) 예연소실(豫燃燒室)은 기존(旣存) 예연소실(豫燃燒室)보다 약(約) $-6^{\circ}C$의 시동성(始動性) 향상(向上)을 나타냈다.

• Journal of Acupuncture Research
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• 제29권6호
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• pp.85-89
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• 2012

Objectives : This study is to evaluate the current situation of Japanese tourists for medical tour of Daejeon University hospital and to draw up a plan for better policies. Methods : 59 Japanese tourists visiting oriental medicines hospital of Daejeon University from January 2012 to September 2012, were analysed in the statistics. And 8 of them answer a questionnaire about reasons for selection of Daejeon University hospital, satisfaction for thread embedding therapy and side effects of thread embedding therapy. Results : A total of 59 foreigners visited oriental medicines hospital of Daejeon University for medical service, consisting of 54 females(92 %), the thirties to fifties 71 % by age. The 87.5 % of patients answered that the reason for choosing this hospital was the subsidization of the medical expenses, and 50 % for appropriate payment, 37.5 % for safety, 12.5 % for recommendation of the people who had good experience at this hospital. The 71% of patients selected thread-embedding therapy for treating wrinkles. The degree of satisfaction was evaluated as quite satisfaction of 87.5 %, full satisfaction of 12.5 % showing that a whole number of the patients treated with thread-embedding therapy showed relative satisfaction. This evaluation is, however, a short term survey which should lead to a further term study. For the evaluation of side effects of thread-embedding therapy, 75 % of patients answered as pain occurred during the therapy, 62.5 % as edema, 50 % as hypodermal bleeding. Conclusion : First of all, there should be more constructive promotion and support for medical tour of oriental medicines, ultimately leading to promoting better clusters of oriental medicines. Secondly, support in terms of a medical law should be established for medical disputes, and the best follow-up service should be considered.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5327-5332
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• 2012

In this review, we describe the patterns of known immunological components in breast milk and examine the relationship between breastfeeding and reduced risk of breast cancer. The top risk factors for breast cancer are a woman's age and family history, specifically having a first-degree relative with breast cancer. Women that have a history of breastfeeding have been shown to have reduced rates of breast cancer. Although the specific cause has not been elucidated, previous studies have suggested that breastfeeding reduces the risk of breast cancer primarily through two mechanisms: the differentiation of breast tissue and reduction in the lifetime number of ovulatory cycles. In this context, one of the primary components of human milk that is postulated to affect cancer risk is alpha-lactalbumin. Tumour cell death can be induced by HAMLET (a human milk complex of alpha-lactalbumin and oleic acid). HAMLET induces apoptosis only in tumour cells, while normal differentiated cells are resistant to its effects. Therefore, HAMLET may provide safe and effective protection against the development of breast cancer. Mothers should be encouraged to breastfeed their babies because the complex components of human milk secretion make it an ideal food source for babies and clinical evidence has shown that there is a lower risk of breast cancer in women who breastfed their babies.

• 한국환경과학회지
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• 제26권11호
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• pp.1223-1233
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• 2017

The purposes of this study are to analyze the degree of satisfaction on forest experience among children, based on a survey of teachers and parents who lead them, and to make proposals based upon the findings. The survey was performed in forest experience for children at Apsan Park in Daegu. The results are as follows. First, there were 78 respondents comprising 34 teachers, 39 parents, and 5 others. The teachers' age groups were distributed evenly between the 20s and 40s and parents' 51.3% were in their 30s and 46.2% in their 40s. Second, all participants responded that forest experience is necessary for children. 80.8% of respondents required continually additional construction. Specifically, parents insisted that forest experience for children should be built up more than the teachers did. Third, as a result of the management and program satisfaction of forest experience for children, 38.5% of respondents wanted increased access and another 38.5% desired unlimited access. In addition, the older teachers preferred more flexible access. Fourth, the safe facility topped the list of the four facilities ranked by importance with 0.39 points, followed by the learning experience field, the shelter facility, and the discretional facility. This study aims to build up basic data in order to make and practically manage forest experiences for children. Therefore, through continuous research, forest experience for children should be established as a practical experience spaces for children.

• 한국지반신소재학회논문집
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• 제16권4호
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• pp.93-101
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• 2017

본 연구에서는 고소성 점토지반으로 구성된 광양지역의 준설매립층 및 원지반층에서 채취된 자연 시료를 이용하여 기존에 제안된 6가지 방법(Casagrande, Onitsuka, Silva, Becker, Janbu, Karlsrud)으로 선행압밀압력을 산정하는데 있어서 상대적인 용이성을 기준으로 5등급의 가중치 점수를 부여 하였다. 이 때, 높은 등급이 부여된다는 것이 곧바로 정확한 선행압밀압력의 산정을 의미하는 것은 아니므로, 불교란 시료에 의한 일축압축강도를 구한 후 압밀압력과의 상관관계를 나타내는 강도증가율을 평가하였다. 이를 토대로, 각각의 방법으로 평가된 선행압밀압력과 비배수전단강도의 비, 즉, 강도증가율이 국내 해성 점성토 지반의 일반적인 값의 범위인 0.25~0.35 사이의 분포 유무 및 표준편차(강도증가율의 변화폭)를 분석하여 적용성을 평가하였다. 그 결과, Becker 및 Onitsuka 방법의 평균 가중치가 다른 방법들(Casagrande, Janbu, Karlsrud)에 비해 낮고 강도증가율도 국내 해성점토 지반의 일반적인 값의 범위에 있으며, 표준편차도 낮게 평가되어 일관성 있는 평가가 가능한 것으로 분석되었다.

• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2004년도 Annual Meeting and International Symposium
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• pp.47-52
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• 2004

This study was conducted to determine the effects of egg phospholipids [(Phosphatidylcholine (PC) and sphingomyelin (SM)] on intestinal absorption of cholesterol and other lipids. Each rat with Iymph cannula was infused via a duodenal catheter at 3.0 mL/h for 8 h with a lipid emulsion containing triolein, cholesterol and PC in 24 mL PBS. The PC in the lipid emulsion was egg PC (EPC), hydrogenated egg PC (HPC), or soy PC (SPC). The EPC in the lipid emulsion markedly lowered the Iymphatic absorption of cholesterol, compared with SPC and a lipid emulsion containing no PC. The HPC further lowered the absorption of cholesterol. The phospholipid output was not affected by the source of PC infused. The total Iymphatic output of oleic acid (18: 1), the major fatty acid infused in the form of triolein, did not differ among the NPC, SPC and EPC groups, but was significantly lower in the HPC group. The findings provide the first evidence that EPC markedly lowers the Iymphatic absorption of cholesterol under in vivo conditions. The inhibitory effect of EPC appears to be due to the higher degree of saturation of its acyl groups relative to SPC, suggesting that the intestinal absorption of egg cholesterol may be reduced by the presence of PC in e99 yolk. Experiment 2 was designed to determine whether egg SM, structurally similar to PC, also inhibits the Iymphatic absorption of cholesterol. Egg SM lowered the Lymphatic absorption of cholesterol in a dose dependent manner. Likewise, SM lowered the Iymphatic absorption of oleic acid, whereas it had no effect on retinol absorption. SM at a high dose lowered the Iymphatic outputs of both PC and SM, whereas there was no such effect at a lower dose. These results also indicate that luminal egg SM has an inhibitory effect on the intestinal absorption of cholesterol and other lipids of relatively high hydrophobicity.

• 한국초등과학교육학회지:초등과학교육
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• 제17권2호
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• pp.79-90
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• 1998

The purpose of this study is to investigate degree of the concept formation on cell in elementary school teachers and to clarify the patterns of their misconceptions. Data were collected by interview with 120 elementary school teachers, ranged from twenties to fifties in age, working in Taegu city. The instrument was developed by researchers and was categorized into four: cell as the basic units of life, morphology of cell, function of cell, growth of individual from the viewpoint of cell. The results are as follows: First, about 80% of teachers had two perspective outcome of cell: Cells are the basic units of life on earth. But the potato and meat, which we used to eat as food, are not constructed of cells but aggregated of nutrients. Second, most of elementary school teachers recognized that shapes of the cell in organisms were diverse, but some of them only could present several kinds of shape on cell. The 35% of teachers had misconception that shape of cell is all the same in a individual. It shows that this result is caused by lack of opportunity to observe the various kinds of cells. Third, most teachers understood tell can be seen only through a microscope. Yet in comparison with relative size, it was revealed that misconception of cell size was induced by the term of 'basic unit'. In addition, they thought that large organisms are built from large cells, and small organisms from small cells. Fourth, Elementary school teachers used to confuse the terms between chloroplast and chlorophyll, and believed that the genetic material was contained only in the reproductive cells and seeds. It was also revealed that they thought the nutrients such as starch and fat are located at intercellular space. Fifth, the 60% of teachers conceived correctly that growth of individual depends on mitosis and increase in cell number. The rest of them, however, misunderstood that it is due to the increase of tell volume.

• Nutritional Sciences
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• 제5권4호
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• pp.175-183
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• 2002

To compare the effects of various types of dietary fiber on microbial production of short-chain fatty acids (SCFA) and on colon cell proliferation which is used as an intermediate biomarker for colon carcinogenesis, groups of 10 male Sprague-Dawley rats were fed one of four fiber-supplemented diets (6% cellulose, 6% pectin, 6% polydextrose, and a mixture of 3% cellulose and 3% polydextrose) for three weeks. As a control, a fiber-free diet was fed to a separate group of 10 rats. Cell proliferation was measured by in vivo incorporation of bromodeoxyuridine into DNA in the proximal and distal colon, respectively. Luminal concentrations of SCFA were measured by gas chromatography. Dietary fiber significantly influenced microbial production of SCFA in the colon; pectin supplementation produced the highest concentrations of luminal SCFA in both the proximal and distal colon (p<0.05). The degree of individual SCFA production was characterized by a relatively higher increase in butyrate production by the pectin-supplemented diet, and in propionate production by the polydextrose-supplemented diet, resulting in alterations of the molar ratios of acetate, propionate and butyrate. There were significant differences in colon cell proliferation among the diet groups; the pectin-supplemented diet produced a significantly higher effect on cell proliferation of distal colonic epithelial cells (p＜0.05), and the polydextrose-supplemented diet produced an intermediate effect compared to the fiber-free or cellulose-supplemented diet. Increased cell proliferation was correlated to increased luminal concentrations of butyrate in the proximal colon and to increased luminal concentrations of propionate and butyrate in the distal colon (p<0.05). Therefore, these data suggest that dietary fiber may modulate colon cell proliferation by altering luminal SCFA concentrations, particularly butyrate and perhaps propionate. In addition, the present study is the first finding that has demonstrated a relative increase in colon cell proliferation due to supplementation with polydextrose, suggesting that the overuse of this artificially synthesized polysaccharide in food processing technology needs to be carefully evaluated from the public health point of view.