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The Clinical Aspects of Regional Lymphadenitis following BCG Vaccination (BCG 접종 후 국소 림프절염의 임상양상)

  • Bae, Sun Young;Park, Yang Joon;Kim, Jong-Hyun;Oh, Jin Hee;Koh, Dae Kyun;Kang, Jin Han
    • Pediatric Infection and Vaccine
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    • v.13 no.2
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    • pp.137-146
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    • 2006
  • Purpose : A regional lymphadenitis is the most frequent adverse reaction of BCG. In order to find out developmental factors and establish a strategy of management, we investigated the clinical courses of children with lymphadenitis following BCG on the aspect of BCG strains, suppurative rates according to the sizes of lymph node and the clinical difference with or without treatment. Methods : From January 1997 to June 2004, 52 children less than 24 month-age-old diagnosed as BCG lymphadenitis in Department of Pediatrics, St. Vincent's Hospital, The Catholic University of Korea were enrolled. The type of BCG strain, place of vaccination, location and size of lymphadenitis were assessed with medical records, retrospectively. Finally, we analysed the correlations between BCG strains or the sizes of lymph node and natural remission or suppuration. Results : The first detected mean age of BCG lymphadenitis was 5.5 month-age. The larger of the measurement was at the first visiting, the younger of age that was first presented. The most frequent location was the same sided axillary region of BCG injection. Among 52 subjects, 46 cases(88.5%) were vaccinated with intradermal Pastuer strain, and only 5 cases(9.6%) were done with percutaneous multipunctured Tokyo strain. Twenty eight cases(53.8%) were regressed naturally, otherwise 24 cases(46.2%) were suppurated. The larger those were sized, the higher freqeuncies those were suppurated on, significantly. Treatment with medications could not prevent the suppuration and could not shorten the healing periods. Conclusion : We predict that there are differences between the occurrent rate of BCG lymphadenitis and BCG strains or methods. Treatment with medication is not recommended owing to its ineffectiveness. Especially, in case of non-suppurative lymphadenitis should be onlyless influence on the tuberculin skin test, cause less adverse reactions, and is inexpensive. observed without treatment, because it could be regressed naturally. An ideal BCG makes a scar, We should make an effort to choose the best BCG strain that can fulfill such requirements.

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Verification of skin dose according to the location of tumor in Tomotherapy (토모테라피 시 종양의 위치에 따른 피부선량 검증)

  • Yoon, Bo Reum;Park, Su Yeon;Park, Byoung Suk;Kim, Jong Sik;Song, Ki Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.273-280
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    • 2014
  • Purpose : To verify the skin dose in Tomotherapy-based radiation treatment according to the change in tumor locations, skin dose was measured by using Gafchromic EBT3 film and compared with the planned doses to find out the gap between them. Materials and Methods : In this study, to measure the skin dose, I'm RT Phantom(IBA Dosimetry, Germany) was utilized. After obtaining the 2.5mm CT images, tumor locations and skin dose measuring points were set by using Pinnacle(ver 9.2, Philips Medical System, USA). The tumor location was decided to be 5mm and 10mm away from surface of the phantom and center. Considering the attenuation of a Tomo-couch, we ensured a symmetric placement between the ceiling and floor directions of the phantom. The measuring point of skin doses was set to have 3mm and 5mm thickness from the surface. Measurement was done 3 times. By employing TomoHD(TomoHD treatment system, Tomotherapy Inc., Madison, Wisconsin, USA), we devised Tomotherapy plans, measured 3 times by inserting Gafchromic EBT3 film into the phantom and compared the measurement with the skin dose treatment plans. Results : The skin doses in the upper part of the phantom, when the tumor was located in the center, were found to be 7.53 cGy and 7.25 cGy in 5mm and 3mm respectively. If placed 5mm away from the skin in the ceiling direction, doses were 18.06 cGy and 16.89 cGy; if 10mm away, 20.37 cGy and 18.27 cGy, respectively. The skin doses in the lower part of the phantom, when the tumor was located in the center, recorded 8.82 cGy and 8.29 cGy in 5mm and 3mm, each; if located 5mm away from the lower part skin, 21.69 cGy and 19.78 cGy were respectively recorded; and if 10mm away, 20.48 cGy and 19.57 cGy were recorded. If the tumor was placed in the center, skin doses were found to increase by 3.2~17.1% whereas if the tumor is 5mm away from the ceiling part, the figure decreased to 2.8~9.0%. To the Tomo-couch direction, skin doses showed an average increase of 11% or over, compared to the planned treatment. Conclusion : This study found gaps between planned skin doses and actual doses in the Tomotherapy treatment planning. Especially to the Tomo-cocuh direction, skin doses were found to be larger than the planned doses. Thus, during the treatment of tumors near the Tomo-couch, doses will need to be more accurately calculated and more efforts to verify skin doses will be required as well.

Different Perception on Product Attributes of HMR: Focusing on College Students and Consumers (가정간편식의 제품속성에 대한 인식차이: 대학생들과 소비자를 중심으로)

  • Yang, Hoe-Chang;Kim, Jong-Baek;Kim, An-Sik
    • Journal of Distribution Science
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    • v.14 no.2
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    • pp.47-56
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    • 2016
  • Purpose - The purpose of this study is to investigate the difference in the degree of significance and satisfaction perceived by college students and ordinary consumers on the HMR product attributes. Comparison of the difference on HMR product attributes between ordinary consumers and college students who belong to the current and future consumption groups of HMR will provide information for clear marketing strategies and PR on target consumers from the aspects of companies. Also, overall difference on HMR was investigated through IPA(importance-performance analysis) on significance and satisfaction with each product attribute. This result will provide information to food companies that produce or supply HMR products to be supplemented and improved. Finally, IPA was conducted between groups on product attribute to find which difference exists between groups. This result is also expected to provide crucial information to companies as suggested in the first purpose. Research design, data, and methodology - The procedure of analysis is as follows. First, independent sample t-test was conducted on the significance and satisfaction on HMR product attributes. Second, with using IPA, the significance and satisfaction on HMR product attributes of the respondents were checked to investigate marketing strategy direction on overall HRM products. Third, the difference between generations was verified using IPA on the college student and consumer groups. According to this result, the direction of marketing strategy on HRM products was to be proposed to food companies. Results - It was known that consumers consider HMR product attributes statistically and significantly such as nutrient content(nutrition), country of origin, brand, main raw material, packaging, and awareness of manufacturer. They keep after purchase more importantly than college students who considered only volume and price than consumers. In comparison with the difference in satisfaction on HMR product attributes, the college student group was more satisfied than ordinary consumers only in flavor, condition of food additives, and volume. Also, HMR related food companies must maintain taste, cooking method, manufacturing date, expiration date, and safety on current products continuously. Finally, as a result of analysis from the groups, the attributes such as cooking method, manufacturing date, expiration date, and safety were considered significantly with high achievement by the two groups. It was known that college students considered food texture to be important, but consumers considered storage method to be important after purchasing it. Conclusions - There is necessity to differentiate effectiveness of products when releasing HMR products subject to consumers and college students. The result will give great assistance to the improvement of companies, produce or supply HMR products. It will also provide entry strategies on target groups of companies that are planning for entry. The factors that consumers commonly considered not to be significant were brand, package form(appearance), cooking time, and sale(purchase) location, which were found in the comparison with the groups that awareness about manufacturers and storage method after purchase corresponded to college students and that distribution route corresponded to ordinary consumers.

Comparative Analysis of QUAL2E, QUAL2K and CAP Steady State Water Quality Modeling Results in Downstream Areas of the Geum River, Korea (QUAL2E, QUAL2K 및 CAP 모델을 이용한 금강 하류 하천구간 정상상태 수질모델링 결과 비교 분석)

  • Seo, Dongil;Yun, Jong Uk;Lee, Jae Woon
    • Journal of Korean Society of Water and Wastewater
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    • v.22 no.1
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    • pp.121-129
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    • 2008
  • Major factors affecting water quality in rivers are transportation, input of pollutant loads and kinetic transformation of pollutants. Government level decision makings on water quality management are based on steady state water quality modeling. However, it is more than often that such a steady state assumption is far from real situations in rivers. Therefore, it is unavoidable to have modeling errors in water quality modeling especially for steady state modeling for longer period of time. Authors attempted to identify sources of errors in results of steady state models and thus tried to find out ways to minimize those errors. Three water quality models, QUAL2E (Brown et al., 1983), QUAL2K (Chapra et al., 2006) and CAP (Seo and Lee, 2000) were applied to the lower stream of the Geum River. $BOD_5$ and COD tend to underestimate observed data while TN and TP showed relatively smaller errors. QUAL2E model provided best calibration results for BOD5 and TP and QUAL2K model showed best calibration results for TN. Since these errors are only relative values, it was difficult to conclude which model is better performing in certain situations. The most probable reasons for errors in water quality modeling are; 1) inappropriate consideration on flow characteristics, 2) lack of information on incoming pollutant load and 3) inappropriate location of sampling for water quality analysis.

Analysis on Characteristics of Sediment Produce by Landslide in a Basin 1. Simulation of Sediment Produce and its Verification (유역 내에서의 산사태에 의한 토사발생특성 분석 1. 토사발생모의 및 검증)

  • Yoo, Chul-Sang;Kim, Kee-Wook;Kim, Seong-Joon;Lee, Mi-Seon
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.3
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    • pp.133-145
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    • 2010
  • This study analyzed the characteristics of sediment produce by landslide triggered by rainfall. One-dimensional unsaturated groundwater model and infinite slope stability analysis were used to estimate the behavior of soil moisture and slope stability according to rainfall, respectively. Slope stability analysis was performed considering on soil depth and characteristics of trees. As the results considering on recovery of the failed slopes, much amount of sediment was produced in 1963, 1970, and 2002. As the results of verification of simulation results using Landsat 5 TM images, we can find differences of landslide location between the results from model and satellite images. These differences can be caused by uncertainties of the rough parameters in the model. However, in the case that Obong-dam basin was divided into two subbasin, Wangsan-chun and Doma-chun basin, the results of each subbasin show errors around 20%. And only 4% of error occurred in the case of comparing landslide area on the entire Obong-dam basin. These errors seem insignificant considering on the errors which can be caused from the analyses in this study such as estimation of sediment produce, soil cover classification, and estimation of landslide area.

The Correlation between DNA Ploidy and the Clinicohistologic Findings in Colorectal Cancer (대장직장암에서 임상조직학적 소견과 DNA ploidy와의 상관관계)

  • Lee Suk Ho;Kim Hun Jung;Kim Woo Chul;Cho Young Kap;Loh John J K;Woo Ze Hong;Hwamg Tae Sook
    • Radiation Oncology Journal
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    • v.18 no.3
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    • pp.187-193
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    • 2000
  • Purpose : DNA ploidy pattern was shown to correlate with several clinicohistologic findings in several tumors. Aim of this study was to evaluate the correlation of the clinicohistologic findings in colorectal cancer and the failure pattern in rectosigmoid cancer with DNA ploidy. Materials and Methods DNA flow cytometry using the Hedley methods on paraffin embedded specimen from 117 patients with colorectal cancers after curative resection was peformed. We tried to find the correlation between DNA ploidy and various clinicohistologic findings. And then the correlation DNA ploidy and the failure pattern in 75 patients of rectosigmoid cancer was analized. Results : Forty samples (34.2%) from tumors gave aneuploidy histogram. There was no significant difference in the frequency of DNA aneuploidy in terms of age, sex, depth of invasion, location and Dukes stage. But there was a significant correlation between DNA ploidy and the failure rates in Dukes stage B rectosigmoid cancer (P=0.048). Conclusions : These findings suggest that DNA ploidy pattern shows the correlation with the treatment failure rates in Dukes stage B rectosigmoid, but not with many other clinicohistologic findings. However,more patients will be needed to disclose these findings.

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Monitoring of Black Pine Bast Scale, Matsucoccus thunbergianae (Homoptera: Margarodidae) Using Yellow Sticky Trap (황색 끈끈이트랩을 이용한 솔껍질깍지벌레(Homoptera: Margarodidae) 예찰)

  • Lee, Chang Jun;Kim, Dong Soo;Chung, Young Hack;Lee, Sang Myeong;Lee, Suck Jun;Lee, Dong Woon
    • Korean journal of applied entomology
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    • v.57 no.3
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    • pp.143-149
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    • 2018
  • The black pine bast scale (BPBS), Matsucoccus thunbergianae (Homoptera: Margarodidae), is one of the most serious insect pests of Japanese black pine (Pinus thunbergiana) in Korea. The density of BPBS varies by tree, branch, and location, making it difficult to monitor them. This study investigated to find a monitoring method for distribution and occurrence of BPBS on Japanese black pine using the yellow sticky trap. The density of male BPBS on sticky trap and nymphs from the branch of Japanese black pine was highly correlated in various surveyed sites. The number of male BPBS that attracted to the yellow sticky traps was higher in upper crown than the lower crown of P. thunbergiana but this was not statistically significant. The density of BPBS nymphs increases with the increase of the diameter of the branch, but the differences were not significant from 1 to 2.5 cm. BPBS was highly distributed in bottom-faced branch than the upper-faced branch of P. thunbergiana. Therefore, we suggest, the yellow sticky trap for the monitoring of BPBS and when examining the nymph density in branch, it is recommended that the bottom-faced branch of the 2-2.5 cm diameter branch be examined.

Clinicopathologic Risk Factors of Hepatic Recurrence after Curative Resection for Gastric Cancer (위암의 근치적 절제술 후 간재발의 임상병리학적 위험인자)

  • Hwang, Jeong-Hwan;Kim, Chan-Young;Kim, Jong-Hun;Hwang, Yong;Yang, Doo-Hyun
    • Journal of Gastric Cancer
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    • v.5 no.4 s.20
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    • pp.266-272
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    • 2005
  • Purpose: Recurrence occurs in various forms and in different organs after a curative resection of gastric cancer. The most common location for hematogenous recurrence is the liver. The aim of this study was to evaluate the clinicopathological risk factors associated with hepatic recurrence after surgical treatment of gastric cancer. Materials and Methods: We reviewed the medical records of 838 patients who had taken radical surgery for primary gastric cancers at Chonbuk National University Hospital between January 1992 and December 1999. According to the medical records, we retrospectively investigated the association between the clinicopathologic variables and hepatic recurence. Results: Recurrence of gastric cancer was documented in 201 out of the 838 patients (23.98%). Hepatic recurrences were found in 59 out of 201 patients (29.35%). Multiple logistic regression analysis identified the following as independent risk factors of hepatic recurrence: Lauren's Intestinal type (OR, 6.60; 95% Cl, 1.53 to 28.9; p=0.011) and proximal resection of margin below 6 cm (OR, 3.76; 95% Cl, 1.03 to 13.67; P=0.045). Conclusion: Various studies on clinocopathologic risk factors of liver recurrence with molecular biologic research should make possible the prediction of recurrence and help high-risk patients to find appropriate management.

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Phototaxis of Fish 7. Response of Sea-Bass to the Colored Lights (어류의 주광성에 관한 연구 7. 색광에 대한 농성어의 반응)

  • 양용림
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.23 no.4
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    • pp.151-156
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    • 1987
  • The author carried out an experiment to find out the response of sea-bass, Epinephelus septemfasciatus (Thunberg) to the color lights. The experimental tank (360L$\times$50W$\times$55H cm) was set up in a dark room. Six longitudinal sections with 60 cm intervals are marked in the tank to observe the location of the fish. Water depth in the tank was kept 50 cm level. Light bulbs of 20 W at the both ends of the tank projected the light horizontally into the tank. Two different colored filters were selected from four colors of red, blue, yellow, and white, and they were placed in front of the light bulbs to make different colors of light. Light intensity were controlled by use of auxiliary filters intercepted between the bulb and the filter. The fishes were acclimatized in the dark for 50 minutes before they were employed in the experiment. Upon turning on the light, the number of fish in each section was counted 40 times in 30 second intervals, and the mean of the number of fish in each section was given as the gathering rate of the fish. The colors favourited by the fish was found in the order of blue, red, white and yellow in day time, and red, blue, yellow and white at night time. The gathering rate of fish on illumination period was not constant and fluctuated with irregularity. The difference of the gathering rate on two different colors of light was small and the difference was larger in night time then in day time.

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Fire District Adjustment for Improving Fire Service Vulnerable Areas in Jinju (진주시 소방서비스 취약지역 개선을 위한 소방권역 조정)

  • Yoo, Hwan Hee;Koo, Seul
    • Journal of Korean Society for Geospatial Information Science
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    • v.21 no.1
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    • pp.19-26
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    • 2013
  • This study analyzed the vulnerable areas to the fire service in regard to 119 safety centers, currently established in Jinju city. In this study, the district of fire was examined through the analysis of the OD cost matrix to find the transference or increase methods of the existing centers for improving the fire services. The study results demonstrate that the numbers of 119 safety centers were lacking in comparison with the areas of the administrative district in Jinju. In particular, relocation and the transference or increase of centers were required for the Cheonjeon 119 safety centers, which is the creation area of the National Industrial Complex among five 119 safety centers located in Jinju, and the fire service jurisdiction of Munsan 119 safety centers (including Banseong 119 regional unit), which is the location of a big fire risk due to the increase of population according to the development of the new town. In addition, the OD cost matrix analysis in this study reveals the fact that the time of fire service in the Jeonchon Industrial Complex, which is the significantly vulnerable area, will be reduced from 8 minutes to 3.3 minutes if the current Cheonjeon 119 safety center is moved to Gaho-dong. It indicates that the increase of safety centers in Geumsan-myeon areas, where the population has increased rapidly in recent days due to the development of the new town, is keenly needed.