• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.264-264
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• 2006

The nanoparticle-hydrogel complex as a new bone defect replacement matrix, which is composed of the nanoparticles for the sustained release of BMP and the hydrogel for filling the bone defect site and playing a role as a matrix where new bone can grow, is presented. In vivo evaluation of bone formation was characterized by soft X-ray, MT staining, and calcium assay, based on the rat calvarial critical size defect model. The effective bone regeneration was achieved by the BMP-2 loaded nanoparticles in fibrin gel, compare to bare fibrin gel, the nanoparticle-fibrin gel complex without BMP-2, or the BMP-2 in fibrin gel, in terms of the new bone area and the gray level in X-ray, the bone marrow are, and the calcium content in the initial defect site. These findings suggest that the BMP-2 loaded nanoparticle-fibrin gel complex can a promising candidate for a new bone defect replacement matrix.

• 대한기계학회논문집A
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• 제24권10호
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• pp.2543-2551
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• 2000

Precision injection molding is an important technology for improving productivity and lowering costs in the fields of medical components, lenses and electrical connectors. The quality of injection molded parts is affected by various processing conditions such as filling time and packing pressure profile. It is difficult to consider all the variables at the same time for prediction of the quality. In this study, the genetic algorithm was used to obtain the optimal processing conditions for minimizing the volumetric shrinkage of molded parts. For a higher convergence rate, the method of design of experiments was used to analyze the relationship between processing conditions and volumetric shrinkage of molded parts, which served as analysis tool for the capability of searching optimal processing conditions but also greatly reduces the calculation time by utilizing the information of searching area. As a practical example, compact disks that require micron-level precision were chosen for the study.

• Advances in concrete construction
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• 제10권5호
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• pp.417-429
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• 2020

Waste glass is a global solid waste with huge reserves. The discarded waste glass has caused a series of problems such as resource waste and environmental pollution, so it is urgent to recycle waste glass with high replacement level. Glass powder (GP), as a supplementary cementitious material (SCM), used in cement-based materials has already become one of the important ways to recycle waste glass mainly attributed to its pozzolanic reaction and filling effect, especially to the suppressed ASR expansion. This paper demonstrates an overview of the properties of GP and its effect on the fresh and mechanical properties of cement-based materials. The study found that the influence of GP on the performance of cement-based materials mainly depends on its content, particle size, color and type, curing conditions, and other SCMs. Finally, based on the problems involved in the investigation of concrete containing GP, some corresponding suggestions and efforts are given to further guide the utilization of GP in cement-based materials.

• 대한조선학회논문집
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• 제47권1호
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• pp.38-46
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• 2010

This study aims at investigating the effect of the baffle height on the liquid sloshing in the three-dimensional (3D) rectangular tank. In order to simulate the 3D incompressible viscous two-phase flow in the 3D tank with partially filled liquid, the present study has adopted the volume of fluid (VOF) method based on the finite-volume method which has been well verified by comparing with the results of the relevant previous researches. The ratio of the baffle height ($h_B$) to filling level (h) has been changed in the range of $0{\leq}h_B/h{\leq}1.2$ to observe the effect on the impact loads on the side wall and free surface behavior. Generally, as baffle height increases, the impact pressure on the wall decreases and the deformation of free surface becomes weaker. However it seemed that a critical ratio of the baffle height existed to reveal the lowest impact pressure on the wall. Consequently, $h_B/h=0.8$ among $h_B/hs$ considered in the study showed the lowest impact pressure.

• 한국해안·해양공학회논문집
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• 제31권6호
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• pp.403-408
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• 2019

일반적으로 유공벽을 갖는 케이슨(유공케이슨)은 직립식 구조물 벽면에 유공부를 설치하여 반사파의 저감, 월파량의 저감 등의 목적으로 사용된다. 본 연구에서는 유공케이슨 유수실을 골재(사석)로 채운 형태의 구조물에 대한 수리특성(반사계수)을 수리모형실험을 통해 검토하였다. 유수실을 사석으로 채운 경우가 유수실이 비어있는 일반적인 형상보다는 반사계수가 크게 나타났으나, 속채움재를 유수실에 설치하여 중량을 확보함으로서 구조물의 안정성을 확보하고, 일정 수준에서 수리특성을 만족할 수 있는 것으로 검토되었다.

• 한국치위생학회지
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• 제15권4호
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• pp.603-611
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• 2015

Objectives: The purpose of the study is to investigate the academic achievement in comprehensive dental hygiene courses using MBTI personality type. This study will provide the various pedagogical approaches in the dental hygiene education. Methods: A self-reported questionnaire was completed by 58 dental hygiene students in Chungnam from December, 2012 to March, 2014. The questionnaire consisted of academic achievement of comprehensive dental hygiene course and communication skills, After filling out the questionnaire, the students completed MBTI personality type sheet. Results: The students were categorized as extroversion type (58.6%), sensing type (70.7%), feeling type (56.9%), and perceiving type (67.2%). In the academic achievement, extroversion and judging personality type students had higher self-efficacy than the students of introversion and perceiving types. The extroversion personality type students also had the higher assignment level and confidence than the introversion type. Conclusions: In order to enhance the understanding and learning capacity of the students, dental hygiene professors should understand the differences in achievement levels due to different personality types so that they can utilize better pedagogical approaches.

• BMB Reports
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• 제34권6호
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• pp.502-508
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• 2001

A cDNA, encoding the human growth hormone (hGH), was synthesized based on the known 191 amino acid sequence. Its codon usage was optimized for a high level expression in Escherichia coli. Unique restriction sites were incorporated throughout the gene to facilitate mutagenesis in further studies. To minimize an initiation translation problem, a 624-bp cassette that contained a ribosome binding site and a start codon were fused to the hGH-coding sequence that was flanked between the EcoRI and HindIII sites. The whole fragment was synthesized by an overlapped extension of eight long synthetic oligonucleotides. The four-short duplexes of DNA, which were first formed by annealing and filling-in with a Klenow fragment, were assembled to form a complete hGH gene. The hGH was cloned and expressed successfully using a pET17b plasmid that contained the T7 promoter. Recombinant hGH yielded as much as 20% of the total cellular proteins. However, the majority of the protein was in the form of insoluble inclusion bodies. N-terminal amino acid sequencing also showed that the hGH produced in E. coli contained formyl-methionine. This study provides a useful model for synthesis of the gene of interest and production of recombinant proteins in E. coli.

• Journal of applied mathematics & informatics
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• 제19권1_2호
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• pp.397-414
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• 2005

In the existing literature, most of the purchasing models were developed only for retailers problem ignoring the constraint of storage capacity of retailers shop/showroom. In this paper, we have developed a deterministic model of wholesaler-retailers' problem of single product. The storage capacity of wholesaler's warehouse/showroom and retailers' showroom/shop are assumed to be finite. The items are transported from wholesaler's warehouse to retailers' Own Warehouse (OW) in a lot. The customer's demand is assumed to be displayed inventory level dependent. Demands are met from OW and that spaces of OW will immediately be filled by shifting the same amount from the Rented Warehouse (RW) till the RW is empty. The time duration between selling from OW and filling up its space by new ones from RW is negligible. According to relative size of the retailers' existing (own) warehouse capacity and the demand factors, different scenarios are identified. Our objectives are to optimize the cost functions of wholesaler and two retailers separately. To solve this problem, a real coded Genetic Algorithm (GA) with roulette wheel selection/reproduction, whole arithmetic crossover and non-uniform mutation is developed. Finally a numerical example is presented to illustrate the results for different scenarios. To compare the results of GA, Generalised Reduced Gradient Method has been used for the problem. Also, a sensitivity analysis has been performed to study the variations of the optimal average cost with respect to the different parameters.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1563-1565
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• 2008

Hydrophobic plastic plates employing nano surface features are injection molded using thermoplastic materials. A variotherm molding process is devised for filling the nano pores and releasing the molded nano features from the master. The size of the molded nano surface features are about 100nm in diameter and 200nm in height. The size of the molded plate is about 30mm x 30mm and the thickness is 1mm. As molding materials, Polypropylene, PMMA, COC and PC are employed, which are all typical commodity thermoplastic materials. The mold temperature(stamper temperature) is investigated as a major processing parameter for molding high aspect ratio nano surface features. Almost fully molded nano features are fabricated above a certain level of mold temperature depends on the employing material. The contact angles on the injection molded plates are measured to estimate the hydrophobicity and found to have higher contact angle up to 180% compared to the blank plate with no surface features.

• Journal of Communications and Networks
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• 제18권6호
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• pp.902-912
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• 2016

Recent advances in energy harvesting (EH) technology have motivated the adoption of rechargeable mobile devices for communications. In this paper, we consider a point-to-point (P2P) wireless communication system in which an EH transmitter with a non-ideal rechargeable battery is required to send a given fixed number of bits to the receiver before they expire according to a preset delay constraint. Due to the possible energy loss in the storage process, the harvest-use-and-store (HUS) architecture is adopted. We characterize the properties of the optimal solutions, for additive white Gaussian channels (AWGNs) and then block-fading channels, that maximize the energy efficiency (i.e., battery residual) subject to a given rate requirement. Interestingly, it is shown that the optimal solution has a water-filling interpretation with double thresholds and that both thresholds are monotonic. Based on this, we investigate the optimal double-threshold based allocation policy and devise an algorithm to achieve the solution. Numerical results are provided to validate the theoretical analysis and to compare the optimal solutions with existing schemes.