The purpose of this study was to evaluate the effect of Korean red ginseng (KRG) on ocular blood flow in patients with glaucoma. In a prospective, randomized, placebo-controlled, double-masked crossover trial, 36 patients with open-angle glaucoma were consecutively recruited. Subjects were randomly assigned into two groups. Group A received 1.5 g KRG, administered orally three times daily for 12 weeks, followed by a wash-out period of 8 weeks and 12 weeks of placebo treatment (identical capsules filled with 1.5 g corn starch). Group B underwent the same regimen, but took the placebo first and then KRG. Blood pressure, heart rate, and intraocular pressure were measured at baseline and at the end of each phase of the study. Visual field examination and ocular blood flow measurements by the Heidelberg Retina Flowmeter were performed at baseline and at the end of each phase of the study. Changes in blood pressure, heart rate, intraocular pressure, visual field indices, and retinal peripapillary blood flow were evaluated. Blood pressure, heart rate, intraocular pressure, and visual field indices did not change after placebo or KRG treatment. After KRG treatment, retinal peripapillary blood flow in the temporal peripapillary region significantly improved (p=0.005). No significant changes were found in retinal peripapillary blood flow in either the rim region or the nasal peripapillary region (p=0.051 and 0.278, respectively). KRG ingestion appears to improve retinal peripapillary blood flow in patients with open-angle glaucoma. These results imply that KRG ingestion might be helpful for glaucoma management.
We have analyzed various tolerances of the multi-configurative microscopic system for inspecting the wire-bonding of a reed frame by using the Gaussian bracket method and the equivalent lens method. The tolerances for the curvature and the thickness, which are axial symmetric tolerances, are given by varying the back focal length within a fecal depth under diffraction-limited conditions. Moreover, by using the trial and error method, the axial non-symmetric tolerances for decenter and tilt are established by assigning the 5% variation of MTF(modulation transfer function) at the spatial frequency of 50 lp/mm and at the field angle of 0.7 field. As the tolerances with the most probable distribution are distributed within the range of the decay rate of less than 5% independent of the probability distribution of tolerances, we can achieve completely the desired design performances of the multi-configurative microscopic system by using the various ranges of these tolerances.
Zahir, Z.A.;Munir, A.;Asghar, H.N.;Shaharoona, B.;Arshad, M.
Journal of Microbiology and Biotechnology
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v.18
no.5
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pp.958-963
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2008
A series of experiments were conducted to assess the effectiveness of rhizobacteria containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase for growth promotion of peas under drought conditions. Ten rhizobacteria isolated from the rhizosphere of different crops (peas, wheat, and maize) were screened for their growth promoting ability in peas under axenic condition. Three rhizobacterial isolates, Pseudomonas fluorescens biotype G (ACC-5), P. fluorescens (ACC-14), and P. putida biotype A (Q-7), were selected for pot trial on the basis of their source, ACC deaminase activity, root colonization, and growth promoting activity under axenic conditions. Inoculated and uninoculated (control) seeds of pea cultivar 2000 were sown in pots (4 seeds/pot) at different soil moisture levels (25, 50, 75, and 100% of field capacity). Results revealed that decreasing the soil moisture levels from 100 to 25% of field capacity significantly decreased the growth of peas. However, inoculation of peas with rhizobacteria containing ACC deaminase significantly decreased the "drought stress imposed effects" on growth of peas, although with variable efficacy at different moisture levels. At the lowest soil moisture level (25% field capacity), rhizobacterial isolate Pseudomonas fluorescens biotype G (ACC-5) was found to be more promising compared with the other isolates, as it caused maximum increases in fresh weight, dry weight, root length, shoot length, number of leaves per plant, and water use efficiency on fresh and dry weight basis (45, 150, 92, 45, 140, 46, and 147%, respectively) compared with respective uninoculated controls. It is highly likely that rhizobacteria containing ACC deaminase might have decreased the drought-stress induced ethylene in inoculated plants, which resulted in better growth of plants even at low moisture levels. Therefore, inoculation with rhizobacteria containing ACC deaminase could be helpful in eliminating the inhibitory effects of drought stress on the growth of peas.
Increasing utilization of radiation and RI (Radioisotope) in nuclear industry including non-power area has achieved sustainable development of radiation industry. Industries are no longer confined by a single technology or abilities but expanded for application gradually. RI-Biomics fields are one of the convergence technology that is recognized on a high-tech industry. Unlike the conventional industry, RI-Biomics field needs to various specialists to perform related task. There is no domestic training program to educate the whole process. This study aims to suggest the plan for improvement of practical skills for specialists in RI-Biomics through development of our training program. For this purpose, we have first investigated the opinion about classification scheme from experts and then analyzed the results in order to reflecting our training program. Based on analyzed results, conformity assessment was executed to organize curriculum through status of constructed device and instructor in domestic. Our training program was performed jointly with KAERI (Korea Atomic Energy Research Institute). RI-Biomics center is prepared with facilities of overall experiment to improve quality of education. Due to the fact that specialists have routine task, we organized a five-day short course to reflect temporal difficulties. We performed a trial operation to 6 participants in RI-Biomics field. Through the survey for the specialists who participated in the program, we evaluated the efficiency of our training program. The results showed that participants were satisfied with the organized curriculum and educational materials. Therefore, our program is expected to be utilized as basic research data to develop feasible program for policy development and to improve practical skills in RI-Biomics.
Background: An important consideration for the risk assessment of transgenic plants is their overwintering potential in a natural ecosystem, which allows the survival of the seed bank and may lead to seed reproduction. Here, we investigated the overwintering of sunflower (Helianthus annuus L.) seeds in the laboratory (temperatures: -5, -1, 5, and 10℃) and in the field (burial depth: 0, 5, 15, and 30 cm) as a case study to examine the invasiveness of transgenic crops. Results: Sunflower seeds germinated when incubated at 5℃ and 10℃ for 2, 4, 6, and 12 weeks but not when incubated at -5℃ or -1℃. However, the seeds incubated at -5℃ or -1℃ germinated when they were transferred to the optimal germination temperature (25℃). Up to 16.5% and 15.0% of seeds were dormant when cultured at sub-zero temperatures in a Petri dish containing filter paper and soil, respectively. In the field trial, soil temperature, moisture, and microbial communities differed significantly between soil depths. Germination-related microorganisms were more distributed on the soil surface. Seeds buried on the surface decayed rapidly from 4 weeks after burial, whereas those buried at depths of 15 cm and 30 cm germinated even 16 weeks after burial. No dormancy was detected for seeds buried at any depth. Conclusions: Although sunflower seeds did not overwinter in situ in this study, we cannot exclude the possibility that these seeds lie dormant at sub-zero temperatures and then germinate at optimal temperatures in nature.
Park, Si-Sam;Park, Sung-Chul;Jung, Sung-Pill;Kim, Hong-Taek
Journal of the Korean GEO-environmental Society
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v.5
no.2
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pp.41-49
/
2004
In this study, a newly modified soil nailing technology named as the SPN (Spiral Pipe Nailing) system, is developed to self drilling method can apply to ground which is hard to keep shape of bore hole. And limit equilibrium analysis with simplified trial wedge method while length ratio and bond ratio being altered was performed to evaluate slope stability considered of tensile strength and bending stiffness. Also, using $FLAC^{2D}$ program, superiority of the SPN system was compared to the GSN (General Soil Nailing) system about an example section. And effects of various factors related to the design of the SPN system, such as the type of drilling method and the bit, are examined throughout a series of the displacement-controlled field pull-out tests. As a result, the SPN system is better than the GSN system in slope stability because of having larger bending stiffness, tensile strength and unit skin friction. And results of simplified trial wedge method are similar to results of TALREN 97 program, commercial limit equilibrium analysis computer software, about an example section. Consequently, it will find out of that the SPN system reduce displacements and settlements in down excavation process as well as to increase the global stability.
In recent years the field application of high performance concrete has been increased to improve the quality and reliability of concrete structures. The mix design of the high performance concrete includes the 2 set-off mixture theory of mortar and coarse aggregate and that of paste and aggregate. The 2 set-off mixture theory of mortar and coarse aggregate has a problem of having to determine its value through repeated experiments in applying the rheological characteristics of mortar. The 2 set-off mixture theory of paste and aggregate has never been applied to high performance concrete since it doesn't take into account the relationship between optimum fine aggregate ratio and unit volume of powder nor does it consider the critical aggregate volume ratio. As the mixture theory of these high performance concretes, unlike that of general concrete, focuses on flowability and charge-ability, it does not consider intensity features in mix design also, the unit quantity of the materials used is determined by trial and error method in the same way as general concrete. This study is designed to reduce the frequency of trial and error by accurately calculating the optimum fine aggregate ratio, which makes it possible to minimize the aperture of aggregate in use by introducing the maximum density theory to the mix design of high performance concrete. Also, it is intended to propose a simple and reasonable mix design for high performance concrete meeting the requirements for both intensity and flowability. The mix design proposed in this study may reduce trial and error and conveniently produce high performance concrete which has self-chargeability by using more than the minimum unit volume of powder and optimum fine aggregate with minimum porosity.
Quality assurance may be defined as the complete set of systemic actions that is required to achieve a better treatment result by standardizing treatment and by using various audit programs. In general, application of a quality assurance program in surgery is considered to be more difficult than it is in chemotherapy or radiotherapy. However, recently, the importance of quality assurance in the surgical field has been emphasized in clinical trials comparing different surgical procedures and evaluating the role of postoperative adjuvant therapy. In the case of gastric cancer surgery, excellent quality assurance programs have rarely been applied in most large prospective clinical trials. Although the quality assurance in Dutch trial was conducted very systemically and strictly, the situation is quite different from ours. On the other hand, several quality assurance programs in Japanese trials comparing D2 and D2 plus para-arotic lymph node dissection seem to be applicable to Korean clinical trials. Several factors, including selection of appropriate surgeons based on personal experience and annual number of operations, standardization of surgical procedures by education and consensus, development of a unified database program, application of standardized perioperative management, and standardization of pathologic examination, are required to guarantee a successful multi-institutional prospective clinical trial. In contrast, one needs to realize that protocols that are too strict and sophisticated can make the enrollment of patients and surgeons more difficult and can promote protocol violation during the clinical trials. (J Korean Gastric Cancer Assoc 2005;5:79-88)
A trial product of monogranular compound fertilizer for sesame under vinyle mulching cultivations was manufactured using the principal sources of urea, diammonium phosphate and muriate of potash in combination with a filler of zeolite and a binder of liquid waste from glutamic acid fermentation. Two field experiments using transparent vinyl mulching for single-crop cultivation and black vinyl mulching for cultivation after wheat and barley cropping were carried out to evalute their effects on sesame and the results obtained were as follows. Plant height and stem diameter of the trial product in sesame plant were higher and better than those of NPK split application and NPK all basic application. As the yield of the trial product was higher and similar to the NPK application plots in transparent and black vinyl mulching treatment respectively, the one time basic application of a developed monogranular compound fertilizer for sesame was possible under vinyl mulching cultivation.
Journal of the Korean Institute of Landscape Architecture
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v.44
no.1
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pp.40-50
/
2016
A BIM, which is being applied actively to the construction and civil construction industries, is a technology that can maximize efficiency of various sectors from initial planning and design, construction, and maintenance, to demolition; however, it is in the introductory phase in the field of domestic landscaping. In order to introduce and promote BIM in the field of landscape design, this study developed a prototype of a library and template and analyzed the performance of trial application. For the development of a prototype, annotations and types were analyzed from floor plans of existing small parks, and components of landscape template were deduced. Based on this, play facilities, pergola, and benches were madeintofamily and templates, making automatic design possible. In addition, annotations and tags that are often used in landscape design were made, and a 3D view was materialized through visibility/graphic reassignment. As for tables and quantities, boundary stone table, mounding table, summary sheet of quantities, table of contents, and summary sheet of packaging quantities were grouped and connected with floor plans; regarding landscaping trees, classification criteria and name of trees that are suitable for domestic situations were applied. A landscape template was created to enable the library file format(rfa) that can be mounted on a building with BIM programs. As for problems that arose after the trial application of the prepared template, some CAD files could not be imported; also, while writing tables, the basis of calculation could not be made automatically. Regarding this, it is thought that functions of a BIM program and template need improvement.
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