• The Korean Journal of Physiology and Pharmacology
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• 제12권6호
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• pp.349-355
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• 2008

To determine the peripheral mechanisms involved in thermal sweating during the hot summers in July before acclimatization and after acclimatization in September, we evaluated the sweating response of healthy subjects (n=10) to acetylcholine (ACh), a primary neurotransmitter involved in peripheral sudomotor sensitivity. The quantitative sudomotor axon reflex test (QSART) measures sympathetic C fiber function after iontophoresed ACh evokes a measurable reliable sweat response. The QSART, at 2 mA for 5 min with 10% ACh, was applied to determine the directly activated (DIR) and axon reflex-mediated (AXR) sweating responses during ACh iontophoresis. The AXR sweat onset-time by the axon reflex was $1.50{\pm}0.32$ min and $1.84{\pm}0.46$ min before acclimatization in July and after acclimatization in September, respectively (p<0.01). The sweat volume of the AXR(l) [during 5 min 10% iontophoresis] by the axon reflex was $1.45{\pm}0.53\;mg/cm^2$ and $0.98{\pm}0.24\;mg/cm^2$ before acclimatization in July and after acclimatization in September, respectively (p<0.001). The sweat volume of the AXR(2) [during 5 min post-iontophoresis] by the axon reflex was $2.06{\pm}0.24\;mg/cm^2$ and $1.39{\pm}0.32\;mg/cm^2$ before and after acclimatization in July and September, respectively (p<0.001). The sweat volume of the DIR was $5.88{\pm}1.33\;mg/cm^2$ and $4.98{\pm}0.94\;mg/cm^2$ before and after acclimatization in July and September, respectively (p<0.01). These findings suggest that lower peripheral sudomotor responses of the ACh receptors are indicative of a blunted sympathetic nerve response to ACh during exposure to hot summer weather conditions.

• 환경위생공학
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• 제17권3호
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• pp.99-109
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• 2002

Charcoal $tube/CS_2$ method are more popularly used than any other in the measurement of the working environment for the exposure evaluation of organic solvent, but it is some weak points that the lower accuracy can be obtained on the polar materials and within the range of the low concentration. Thus solvent desorption method has been developed to make accuracy higher and to overcome some weak points. However, because of high price of adsorption tube for thermal desorption and the short of study on its application to the working environment, it is not popularly used in the domestic industrial hygiene fields. This dissertation aims to develop thermal desorption and adsorption tubes for measuring organic solvents in the working environment, by comparing and analyzing breakthrough condition and adsorption capacity with ACF. Specific surface area of ACF used in this study is wider than the one of AC and micropore of ACF related with adsorption has been developed, and adsorption velocity and adsorption amount are very excellent by linking a pore of surface and an inside well into micropore. 1. Result of analysis on physical characteristics of adsorbent, the specific surface area of ACF was 1.3 times higher than that of AC. Distribution ratio of micropore related to adsorption was 94% on ACF and AC. Result of SEM, micropore of the AC is opened to the surface. In contrast, ACF shows that extremely fast adsorption speed. Because of micropore are exposed on the surface and penetrate through each other. 2. Breakthrough characteristics of adsorbents was not different from slop of breakthrough curve. The effluent concentration reaches 10% of initial concentration($C_{out}/C_{in}=0.1$, break point) of ACF was 30~316min longer than that of AC. Therefore, the adsorption capacities of ACF was 1.1~4.6 times higher than that of AC. ACF can be used as a proper adsorbent for measurement of organic solvent.

• 한국구조물진단유지관리공학회 논문집
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• 제19권6호
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• pp.63-71
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• 2015

본 연구는 섬유를 혼입한 고강도 콘크리트의 온도 변화에 따른 내화특성 분석에 관한 연구로 고강도 콘크리트에 고온이 가해질 경우 발생되는 폭렬현상에 대하여 방지효과가 있는 것으로 알려져 있는 하이브리드섬유와 강섬유를 함께 혼입하여 만든 복합섬유를 사용하여 온도 변화($100{\sim}800^{\circ}C$)에 따른 고강도 콘크리트의 내화특성 및 역학적 메커니즘을 분석하였다. 또한 본 논문에서는 고강도 콘크리트 구조물에서 가장 문제가 되는 폭렬현상을 막는 대책 중의 하나인 섬유 혼입을 통한 방법을 사용하여 SEM 및 XRD 분석 등의 방법으로 고온을 받은 고강도 콘크리트의 열적 특성 및 역학적 특성을 규명하고자 하였다.

• 천문학회보
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• 제39권1호
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• pp.51.1-51.1
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• 2014

DOTIFS is a new multi-object Integral Field Spectrograph (IFS) being designed and fabricated by the Inter-University Center for Astronomy and Astrophysics, Pune, India, (IUCAA) for the Cassegrain side port of the 3.6m Devasthal Optical Telescope (DOT). The telescope is constructed by the Aryabhatta Research Institute of Observational Sciences, Nainital (ARIES). Its main scientific objectives are the physics and kinematics of the ionized gas, star formation and H II regions in nearby galaxies. It is a novel instrument in terms of multi-IFU, built in deployment system, and high throughput. It consists of one magnifier, 16 integral field units (IFUs), and 8 spectrographs. Each IFU is comprised of a microlens array and 144 optical fibers, and has $7.4^{\prime\prime}{\times}8.7^{\prime\prime}$ field of view with 144 spaxel elements with a sampling of 0.8" hexagonal aperture. The IFUs can be deployed on the telescope side port over an 8' diameter focal plane by x-y actuators. 8 Identical, all refractive, dedicated fiber spectrographs will produce 2,304 R~1800 spectra over 370-740nm wavelength range with single exposure. Currently, conceptual and baseline design review had been done, and is in the critical design phase with a review planned for later this year. Some of the components have already arrived. The instrument will see its first light in 2015.

• 한국추진공학회지
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• 제17권2호
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• pp.31-38
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• 2013

본 연구에서는 열습환경에 노출된 탄소섬유/에폭시 복합재의 핀 체결부에 대해 핀 하중시험을 수행하고 수집된 음향방출신호를 분석하여 열습환경이 복합재 핀 체결부의 파괴거동에 미치는 영향을 조사하였다. 이때 시편은 환경조건에 노출되기 전의 시편(Base), 상온침수환경에 노출된 시편(RT), 고온침수 환경에 노출된 시편(HT)으로 구분하였다. 연구결과에 의하면 RT 시편과 HT 시편의 베어링 강도는 Base 시편에 비해 각각 2.2%와 13% 감소하였다. 음향방출신호의 경우 시편 종류에 따라 파손이 가속화되는 시점이 달라짐을 나타내었으며 RT 시편과 HT 시편은 Base 시편에 비해 모재균열에 의한 이벤트가 감소하는 경향이 나타났다. 이로 미루어 판단하면 열습환경은 복합재 핀 체결부의 음향방출신호뿐 아니라 계면특성의 저하도 초래함을 알 수 있었다.

• 대한본초학회지
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• 제30권2호
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• pp.25-30
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• 2015

Objectives : Laver (Porphyra tenera), a red algae species, is one of the most widely consumed edible seaweed in Korea. Laver contains various substances such as essential amino acid, fiber, minerals and polyphenols that benefit human health. In the present study, we prepared ethanol extracts from commercially processed product of Porphyra tenera, and evaluated the growth inhibitory effect against human oral squamous carcinoma YD-10B cells. Methods : Cell viability was measured by MTT assay. Apoptosis was confirmed by TUNEL assay and flow cytometry with the green fluorescent dye FITC annexin V entering apoptotic cells and the red fluorescent dye PI not entering. The expression of the relevant proteins was detected using Western blot. Results : Ethanol extracts of Porphyra tenera (PTE, $50-200{\mu}g/m{\ell}$) caused a significant decrease of cell viability in a dose dependant manner. The cell death occurred as a result of apoptotic process as determined by TUNEL assay and flow cytometric analysis. In line with this observation, decrease in procaspase proteins and increase in cytosolic cytochrome c were observed in cells treated with PTE. In addition, exposure to PTE decreased the expression levels of Bcl-2, and induced PARP cleavage and AIF translocation from mitochondria to nucleus. Conclusions : In conclusion, PTE exerts anti-cancer effects by inducing apoptosis via caspase activation and AIF nuclear translocation in YD-10B cells. These results provide evidence for the possible therapeutic effect of Porphyra tenera in oral cancer cells.

• Composites Research
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• 제35권6호
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• pp.425-430
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• 2022

수소가스용 압력용기의 안전성 평가를 위해 다양한 내구성 시험이 요구된다. 고온 정압 시험은 고압(875 bar) 하에 고온(85℃ 이상)에서 장시간(1,000시간) 유지하여 수소 용기의 내구성을 시험하는 방법이며 승용차용 용기에 한정되어 있다. 하지만 대용량 수소버스용 용기와 관련된 고온 정압 시험의 국제 기준은 논의 초기 단계이며, 시험의 효율성 및 신뢰성 측면에서 가속시험 기준 제시 등의 현실적 보완이 필요하다. 본 연구에서는 수소버스용 내압용기의 고온 정압 시험 기준을 정립하기 위해 열적환경에 노출된 내압용기 복합재의 기계적 물성평가를 진행하였다. 복합재의 인장강도는 수지의 유리전이온도에 가까워질수록 수지의 열화로 인해 강도가 감소한다. 또한 장시간 유지 시 수지의 후경화로 인해 인장강도의 재상승을 확인할 수 있었다. 따라서 대용량 수소버스용 압력용기의 고온 정압 시험은 탄소섬유 복합재의 에폭시 수지 물성을 바탕으로 시험 조건을 설정해야 한다.

• Journal of Periodontal and Implant Science
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• 제52권1호
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• pp.54-64
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• 2022

Purpose: This in vitro study was conducted to evaluate the effects of different debridement techniques and conditioning procedures on root surface morphology and blood clot stabilization. Methods: Two debridement techniques (curette [CU] vs. high-speed ultrasound [US]) and 2 conditioning procedures (ethylenediaminetetraacetic acid [EDTA] and phosphoric acid [PA]) were used for the study. Seven experimental groups were tested on root surfaces: 1) no treatment (C); 2) CU; 3) US; 4) CU+EDTA; 5) US+EDTA; 6) CU+PA; and 7) US+PA. Three specimens per group were observed under scanning electron microscopy (SEM) for surface characterization. Additional root slices received a blood drop, and clot formation was graded according to the blood element adhesion index by a single operator. Data were statistically analyzed, using a threshold of P<0.05 for statistical significance. Results: The C group displayed the most irregular surface among the tested groups with the complete absence of blood traces. The highest frequency of blood component adhesion was shown in the CU+EDTA group (P<0.05), while no differences were detected between the CU, US+EDTA, and CU+PA groups (P<0.05), which performed better than the US and US+PA groups (P<0.05). Conclusions: In this SEM analysis, EDTA and conventional manual scaling were the most efficient procedures for enhancing smear layer removal, collagen fiber exposure, and clot stabilization on the root surface. This technique is imperative in periodontal healing and regenerative procedures.

• 센서학회지
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• 제31권3호
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• pp.168-174
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• 2022

Hydrogen sulfide(H₂S) gas is a high-risk gas that can cause suffocation or death in severe cases, depending on the concentration of exposure. Various studies to detect this gas are still in progress. In this study, we demonstrate a colorimetric sensor that can detect H₂S gas using its direct color change. The proposed nanofiber sensor containing a dye material named Lead(II) acetate, which changes its color according to H₂S gas reaction, is fabricated by electrospinning. The performance of this sensor is evaluated by measuring RGB changes, ΔE value, and gas selectivity. It has a ΔE value of 5.75 × 10^-3 ΔE/s·ppm, showing improved sensitivity up to 1.4 times that of the existing H₂S color change detection sensor, which is a result of the large surface area of the nanofibers. The selectivity for H₂S gas is confirmed to be an excellent value of almost 70 %.

• 대한환경공학회지
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• 제34권5호
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• pp.345-350
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• 2012

충북의 D-석면광산 인근지역에서 석면이 포함된 토양으로 부터 대기 중으로 비산되는 석면조사와 주민들의 일상생활이나 토양을 경작하는 농업활동 등의 석면노출이 가능한 주요활동에 대한 인체 위해도를 평가하여, 지역주민의 건강 위해성을 미연에 방지하는 대책을 수립하고자 본 연구를 수행하여 다음과 같은 결론을 얻었다. 첫째, 대기 중 석면 모니터링을 위해 바람의 방향을 고려하여 지역주민의 거주지 근처에 시료채취지점을 선정하였다. 이를 위상차현미경으로 분석한 결과, 20개 지점 중에서 12개 지점은 검출한계 이하이고, 8개 지점도 0.0025~0.0029 f/cc 범위로 석면안전관리법의 공기질 관리기준 0.01 f/cc 보다 매우 낮은 수준이었다. 또한 투과전자현미경으로 이 섬유상 물질을 분석한 결과도 석면이 아니거나 검출한계 이하로 나타났다. 일반 대기 중 석면의 악영향은 거의 없는 것으로 추정된다. 둘째, 현장조사와 지역주민의 설문조사를 토대로 활동근 거시료채취 시나리오를 현지 실정에 맞게 설정하였으며, 그 중에서 예초기 작업과 흙파기, 마당쓸기 시나리오의 경우에 위해도의 95% 신뢰상한치가 석면에 대한 활동별 초과생애발암위해도의 허용치 $1{\times}10^{-4}$을 초과하는 것으로 나타났다. 토양 교란활동이 수반되는 농경활동에는 토양에 함유된 석면섬유상 물질이 많이 비산되는 것으로 판단되며, 지역주민의 세심한 주의가 요구된다. 따라서 이에 대한 결과를 바탕으로 환경성 노출원을 가능하다면 원천적으로 차단하여 석면노출을 최소화하고, 지역주민들에게 석면노출 가능성이 있는 환경에 대해 널리 알림으로써 토양을 교란하여 석면이 비산되는 행위를 제한하는 등의 석면으로 인한 건강피해를 줄이는 체계적인 관리대책이 강구되어야 할 것이다.