• Nutrition Research and Practice
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• 제5권2호
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• pp.107-111
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• 2011

The objective of this study was to investigate the hypoglycemic effects of quercetin (QE) in animal models of diabetes mellitus (DM). A starch solution (1 g/kg) with and without QE (100 mg/kg) or acarbose (40 mg/kg) was orally administered to streptozotocin (STZ)-induced diabetic rats after an overnight fast. Postprandial plasma glucose levels were measured and incremental areas under the response curve were calculated. To study the effects of chronic feeding of QE, five-week-old db/db mice were fed an AIN-93G diet, a diet containing QE at 0.08%, or a diet containing acarbose at 0.03% for 7 weeks after 1 week of adaptation. Plasma glucose and insulin, blood glycated hemoglobin, and maltase activity of the small intestine were measured. Oral administration of QE (100 mg/kg) or acarbose (40 mg/kg) to STZ-treated rats significantly decreased incremental plasma glucose levels 30-180 min after a single oral dose of starch and the area under the postprandial glucose response, compared with the control group. QE (0.08% of diet) or acarbose (0.03% of diet) offered to db/db mice significantly reduced both plasma glucose and blood glycated hemoglobin compared to controls without significant influence on plasma insulin. Small intestine maltase activities were significantly reduced by consumption of QE or acarbose. Thus, QE could be effective in controlling fasting and postprandial blood glucose levels in animal models of DM.

• 한국임상수의학회지
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• 제28권1호
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• pp.1-6
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• 2011

천연물 오배자 추출물은 in vitro 선행 연구를 통하여 병원성 세균과 바이러스에 대한 강력한 항균 항바이러스 효과를 확인하였다. 본 연구는 양돈 농장에서 130일간의 장기 임상시험을 통하여 효능평가를 통한 천연물 오배자 추출물의 항균 항바이러스 효과를 규명하고자 수행되었다. 200 마리의 돼지를 천연물 오배자 추출물 투여군과 비투여군으로 2 그룹으로 나누어 130일 동안 양돈농장에서 연구가 수행되었다. 천연물 오배자 추출물 투여군에는 항생제가 없는 사료에 천연물 오배자 추출물을 0.2% 배합하여 급여하였고 비투여군은 항생제가 포함된 일반 사료를 급여하였다. 연구기간 동안 사료섭취량, 체중, 임상증상을 분석하고 시험종료일에 부검하여 육안검사와 미생물학적 검사 및 병리조직학적 검사를 수행하였다. 연구결과 천연물 오배자 추출물은 양돈 산업에서 심각한 문제가 되고 있는 병원성 세균과 바이러스에 대한 강력한 항균 항바이러스 효과를 가지고 있는 것을 확인할 수 있었다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제11권3호
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• pp.199-204
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• 2006

The purpose of this work was to evaluate the development of the anammox process by the use of granular sludge selected from a digestion reactor as a potential seed source in a lab-scale UASB (upflow anaerobic sludge blanket) reactor system. The reactor was operated for approximately 11 months and was fed by synthetic wastewater. After 200 days of feeding with $NH_4^+\;and\;NO_2^-$ as the main substrates, the biomass showed steady signs of ammonium consumption, resulting in over 60% of ammonium nitrogen removal. This report aims to present the results and to more closely examine what occurs after the onset of anammox activity, while the previous work described the start-up experiment and the presence of anammox bacteria in the enriched community using the fluorescence in situ hybridization (FISH) technique. By the last month of operation, the consumed $NO_2^--N/NH_4^+-N$ ratio in the UASB reactor was close to 1.32, the stoichiometric ratio of the anammox reaction. The obtained results from the influent-shutdown test suggested that nitrite concentration would be one key parameter that promotes the anammox reaction during the start-up enrichment of anammox bacteria from granular sludge. During the study period, the sludge color gradually changed from black to red-brownish.

• KSBB Journal
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• 제10권2호
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• pp.170-175
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• 1995

Methylobacterium organophilum을 이용하여 메탄 올로부터 고점성 다당류의 생산에 대한 질소원 이용의 통력학척 분석을 유가식 배양에서 수행하였다. 발효중 세포는 배지 중에 첨가된 질소원이 고갈된 후에도 계속 성장하였고, 에틸란은 질소원 고갈조건 하에서만 생성되였다 세포 성장은 배양초기에 첨가 한 질소원인 암모니아의 농도에 비례적으로 이루어 졌으나, 에릴란 생산은 첨가한 암모니아 농도가 $0.75g/\ell$ 이상에서는 오히려 현저하게 감소하였다. 초기 암모니아 농도가 높아질수록, 비세포중식 속도, 비산물생성 속도, 비기질소비 속도가 감소하였다. 높 은 암모니아 농도의 발효 속도들에 대한 저해작용을 감소시키기 위해, 질소원을 일정농도(암모니아 농도=$0.15g/\ell$) 이하로 유지시키면서 공급하는 유가식 배양법으로 메틸란의 농도를 $12.5g/\ell$ 까지 증가시킬 수있었다.

• 대한가정학회지
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• 제18권4호
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• pp.95-101
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• 1980

This study was carried out to investigate the effect of the diet supplemented with various amounts of ginseng powder on the growth rate and blood glucose level in rat. Male Albino rats, weighing between 90 to 100g, were divided into 5 diet groups of 6 rats each. experimental diets contained 0, 2, 4, 6 and 8% ginseng powder which was substituted for rice powder and were designated C, G-2, G-4, G-6 and G-8, respectively. The diets were fed for 3 weeks. Throughout feeding period, feed consumption, body weight, feed and protein efficiency ratios were measured, organ weights and blood glucose level were determined at the end of the experimental period. the results are summarized as follows. 1. rats in G-2 group consumed the highest amount of diet among all groups. 2. Body weight gain was significantly higher in G-2 and G-4 than in other groups. 3. Feed and protein efficiency ratios were a little higher in G-4 than in control group. And those of group G-8 were the lowest among those of other groups. 4. The weight of liver was significantly lower I G-4 than in control group. The weight of kidney was significantly lower I G-4 and G-8 than in control group. The weight of heart was significantly lower I G-4 and G-8 than in control group. While, the weight of spleen was greater in ginseng powder diet than in control group. 5. Supplementing ginseng powder in diet resulted in deceased nitrogen in liver. 6. Blood glucose was decreased with increased level of ginseng powder diet.

• 대한가정학회지
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• 제32권1호
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• pp.165-180
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• 1994

The change in the police concerning food and dietary life were analyzed in order to provide bases of establishing policy of food and dietary life properly. The last half one century was divided into six periods as follows ; The period since liberlation from Japanese rule(1945-1949) the 1950's (1950-1959) 1960's (1960-1969) 1970's (1970-1979) 1980's (1980-1989) 1990's (1990-1992). Dietary life by 1960's were a life of distress and policies coducted by government took on an relief supply of food at this period. Movement about 'intake of mixed rice with barley and foods from flour' to supress rice consumption were encouraged by government. And Korean recommended dietary allowance was made and the national nutritional survey was practived in the first place by the Ministry of Health and Social Affairs. Dietary life of the country begin to improve sharply along with rice self-sufficiency since 1975 With the growth of food and eating out industry intake of instant food processed food and fast food has increased at the 1980's To ministry of Health and Social Affairs drove campaign of 'Joo-Moon Sik Dahn Je' for dietary life improvement at 1981 The Ministry of Education made and announced a 'School Feeding Law' at 1981 The government that is the Office of Permier and the Ministry of Health and Social Affairs developed compaign for improvement of dietary life and drove 'Jo Eun Sik Dahan Je' with Association of restaurant jointly. Policy on food and dietary life conducted by government up to data were planned mainly dependent on food production supply and demand of food. Infectious diseases continue to decrease with increasing of degenerative diseases which will be required proper management of dietary life. In the future more aggressive intergrated food policy are needed to maintain the public health. Aoso dietary improvement movement should be drived actively.

• 한국어병학회지
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• 제30권2호
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• pp.97-105
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• 2017

Parasitic leeches could directly (through causing poor growth, anemia and wound in the fish) and indirectly (by predisposition of the fish to secondary bacterial and fungal infections) affects their hosts. In the present study, fishes that were attacked by leeches in natural and experimental environment were studied. Pathologic samples were obtained from damages at the site of leech bite, as well as kidney and liver of the fish. Histopathological examination revealed numerous lesions at the site of leech bite including tissue demolition, detachment at the site of leech bite in the epidermis of epithelial tissue in the skin, destructed nucleus in epithelial cells of the skin plus necrosis in the damaged skin and weak inflammatory penetration to acute necrotic damages along with piercing dermis layer. Pathologic lesions in the kidney included some changes such as proliferation by increasing glomerular cells and membrane cells in capillary vein of the kidney, blood cell necrosis in kidney with infiltration of white blood cells mainly mononuclear and less polymorphonuclear which are the symptoms of anemia due to blood feeding and sucking by leeches. There was also a chronic kidney infection probably originated from another part of body such as skin. Moreover, leeches caused hemorrhagic anemia due to blood consumption of the hosts, which led to observation of immature red blood cells. Also results showed that diseases induced by leeched in fish could be acute or chronic, which depends on size of fish, species of leech and severity of infection.

• 대한전자공학회논문지SD
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• 제40권4호
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• pp.85-94
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• 2003

비동기 설계 기법은 시스템 클럭을 사용하지 않고, 동작이 필요한 모듈만 활성화시켜 전력 및 성능면에서 동기식 설계 기법에 비해 높은 성능을 갖는다. 본 논문은 임베디드 컨트롤러인 Intel 80csl과 완전한 명령어 호환성을 갖고, 비동기식 파이프라인 구조로 최적화된 A8051 아키텍쳐를 제안한다. 다양한 어드레싱 모드와 명령어를 제공하는 CISC 명령어 수행 스킴은 동기식 파이프라인 구조에 적합하지 않고 많은 오버헤드를 유발한다. 본 논문에서는 명령어 실행 사이클을 비동기식 파이프라인 수행에 적합하도록 명령어별로 그룹화하고, 동기화 및 다중 실행 사이클로 인한 오버헤드로 발생된 버블을 제거함으로서 최적화하였다. 또한 적합한 분기 처리 기법 및 가변적인 명령어 길이의 처리 방법을 제시함으로서 명령어 수행시 필요한 상태 수를 최소화하고, 명령어 수행의 병렬성을 증가시켰다. 제안된 A8051 아키텍쳐는 Verilog HDL로 설계하여 0.,35㎛ CMOS 공정 표준 셀 라이브러리로 합성하였다. 실험 결과로 A8051은 36㎒ 클럭을 사용하는 인텔 80C51과 다른 비동기 80C51에 비해 약 24배의 성능 향상을 얻었다.

• 수산해양기술연구
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• 제51권4호
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• pp.637-643
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• 2015

The diet composition of juvenile Trachurus japonicus were studied using 195 specimens collected from 2013 (May, June, July, and September) to 2014 (May, June, and July) in the coastal waters of Geumodo, Yeosu, Korea. The size of juvenile T. japonicus ranged from 4.3 to 15.2 cm in body length (BL). Juvenile T. japonicus was carnivorous and crustaceans predators that consumes mainly consumed copepods. Its diet also included small quantities of decapods, cirripedians, nematods, chaetognathans, fishes, amphipods, cumaceans, ostracods and euphausiids. The graphical method for feeding strategy revealed that juvenile T. japonicus is an opportunistic and specialized predator on copepods, especially Corycaeus. affinis, and showed narrow niche width. Juvenile T. japonicus showed ontogenetic diet change. Small size group individuals (4.3-8.0 cm BL) mainly consumed copepods. The portion of this prey item decreased in the large size group (8.0-15.2 cm BL), and this decrease was paralleled with increased consumption of decapods.

• Asian-Australasian Journal of Animal Sciences
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• 제17권1호
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• pp.127-130
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• 2004

Lathyrus sativus, locally known as Khesari, is a leguminous pulse crop grown in many parts of the world for food (used by poor people) and animal feed/fodder. Its seeds are rich in protein and energy but contains anti-nutritional factors prominent among which is ${\beta}$-N-Oxalylamino-L-Alanine (BOAA), a neurotoxin causing lathyrism in humans due to prolong consumption. Keeping in view the chemical characteristics of this toxin and literary facts on L. sativus feeding in terrestrial animals, it was hypothesized that aquatic species may better utilise this ingredient in mixed extruded diets. Diets were prepared with varying levels (0, 10, 18, 26 and 34%) of L. sativus seeds and fed for 60 days to study growth, body composition and digestibility of nutrients. Final body weight, specific growth rate and feed and protein conversion ratio did not differ (p>0.05) between treatments. Crude protein digestibility was reduced (p<0.01) beyond 26% inclusion level of L. sativus. Final carcass composition with regard to protein, lipid and ash did not differ (p>0.05) among the treatments. Comparable craniosomatic, viscerosomatic, renosomatic and hepatic indices and no mortality implies no apparent adverse effect on the vital organs and fish health. It was concluded that L. sativus can be a promising feed ingredient that can be used up to 34% or possibly higher level in fingerlings diet. To our knowledge, it appears to be the first report of its kind under laboratory conditions.