• KIPS Transactions on Software and Data Engineering
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• v.5 no.2
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• pp.69-78
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• 2016

Ischemic stroke is a disease that the brain tissues cannot function by reducing blood flow due to thrombosis or embolisms. Due to the nature of the disease, it is most important to identify the status of cerebral vessel and the medical images are necessarily used for its diagnosis. Among many indicators, brain MRI is most widely utilized because experts can effectively obtain the semantic information such as cerebral anatomy aiding the diagnosis with it. However, in case of emergency diseases like ischemic stroke, even though a intelligent system is required for supporting the prompt diagnosis and treatment, the current systems have some difficulties to provide the information of medical images intuitively. In other words, as the current systems have managed the medical images based on the basic meta-data such as image name, ID and so on, they cannot consider semantic information inherent in medical images. Therefore, in this paper, to provide core information like cerebral anatomy contained in brain MRI, we suggest a template-driven medical images mapping method. The key idea of the method is defining the mapping characteristics between anatomic feature and representative images by using template images that can be representative of the whole brain MRI image set and revealing the semantic relations that only medical experts can check between images. With our method, it will be possible to manage the medical images based on semantic.

• Journal of Korean Society of Transportation
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• v.31 no.5
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• pp.3-15
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• 2013

The purpose of this study is to propose a methodology for operating variable speed limit (VSL) strategies in freeway work zones. A notable feature in this study is to incorporate a multi-criteria decision making process into deriving better VSL strategies. Decision criteria in this study include operational efficiency, safety, and environmental impacts. Travel speed, acceleration noise, and CO2 were used as performance measures for evaluating VSL strategies. A multi-criteria value function was developed through an analytical hierarchical process (AHP) for representing expert's knowledge. Then, a variety of VSL operations scenarios were investigated utilizing a microscopic traffic simulation suite, VISSIM. The proposed methodology would be useful in supporting more efficient, safer, and more environment-friendly traffic operations and control in freeway work zones.

• Journal of the Korean Child Neurology Society
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• v.26 no.4
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• pp.272-275
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• 2018

KBG syndrome is a rare neurodevelopmental disorder characterized by intellectual disability, skeletal anomalies, short stature, craniofacial dysmorphism, and macrodontia. ANKRD11 gene mutation and 16q24.3 microdeletion have been reported to cause KBG syndrome. Here, we report two patients with ANKRD11 mutations who initially presented with neurologic symptoms such as developmental delay and seizures. Patient 1 was a 23-month-old boy who presented with a global developmental delay. Language delay was the most dominant feature. He had hypertelorism, hearing impairment, and behavior problems characterized as hyperactivity. A c.1903_1907delAAACA (p.Lys635GInfsTer26) mutation in ANKRD11 was identified with diagnostic exome sequencing. Patient 2 was a 14-month-old boy with developmental delay and seizure. He also had atrial septum defect, and ventricular septal defect. Generalized tonic seizures began at the age of 8 months. Electroencephalography showed generalized sharp and slow wave pattern. Seizures did not respond to antiepileptic drugs. A loss of function mutation c.5350_5351delTC (p.ser1784HisfsTer12) in ANKRD11 was identified with diagnostic exome sequencing. In both cases, characteristic features of KBG syndrome such as short stature or macrodontia, were absent, and they visited the hospital due to neurological symptoms. These findings suggest that more patients with mild phenotypes of KBG syndrome are being recognized with advances in diagnostic exome sequencing genetic technologies.

• BMB Reports
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• v.52 no.10
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• pp.595-600
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• 2019

Cardiac fibrosis is a common feature in chronic hypertension patients with advanced heart failure, and endothelial-to-mesenchymal transition (EndMT) is known to promote Angiotensin II (Ang II)-mediated cardiac fibrosis. Previous studies have suggested a potential role for the transcription factor, ETS-1, in Ang II-mediated cardiac remodeling, however the mechanism are not well defined. In this study, we found that mice with endothelial Ets-1 deletion showed reduced cardiac fibrosis and hypertrophy following Ang II infusion. The reduced cardiac fibrosis was accompanied by decreased expression of fibrotic matrix genes, reduced EndMT with decreased Snail, Slug, Twist, and ZEB1 expression, as well as reduced cardiac hypertrophy and expression of hypertrophy-associated genes was observed. In vitro studies using cultured H5V cells further confirmed that ETS-1 knockdown inhibited $TGF-{\beta}1$-induced EndMT. This study revealed that deletion of endothelial Ets-1 attenuated Ang II-induced cardiac fibrosis via inhibition of EndMT, indicating an important ETS-1 function in mediating EndMT. Inhibition of ETS-1 could be a potential therapeutic strategy for treatment of heart failure secondary to chronic hypertension.

• Korean Journal of Optics and Photonics
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• v.31 no.1
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• pp.7-12
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• 2020

In this paper, we experimentally investigate the fiber fuse in single-mode 2-kW-class high-power fiber amplifiers, depending on the cooling method at the splicing point. We measured the temperature of the splicing point between the pump-signal combiner and gain fiber as a function of laser output power. The temperature of the splicing point increased from 20 to 32℃ with a slope of 0.01℃/W, up to 1.2 kW of laser output power. At higher powers the temperature of the splicing point increased dramatically, with a slope of 0.08℃/W. After that, the fiber amplifier was destroyed during operation at 1.96 kW of output power by fiber fuse. The bullet shape, a common feature of fiber fuse, was observed in the damaged passive fiber core of the pump-signal combiner. Later, we adopted an improved water-cooled cold plate to increase the cooling efficiency at the splicing point, and investigated the laser output power. The temperature at the splicing point was 35.8℃ with a temperature-rise slope of 0.007℃/W at the maximum output power of 2.05 kW. The beam quality M² was measured to be less than 1.3, and the output beam's profile was a stable Gaussian shape. Finally, neither fiber fuse nor mode instability was observed in the fiber amplifier at the maximum output power of 2.05 kW.

• Cross-Cultural Studies
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• v.45
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• pp.109-143
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• 2016

This article examines distinctive linguistic shifts of translational English in an effort to verify the validity of the translation universals hypotheses, including simplification, explicitation, normalization and leveling-out, which have been most heavily explored to date. A large-scale study involving comparable corpora of translated and non-translated English newspaper texts has been carried out to typify particular linguistic attributes inherent in translated texts. The main findings are as follows. First, by employing the parameters of STTR, top-to-bottom frequency words, and mean values of sentence lengths, the translational instances of simplification have been detected across the translated English newspaper corpora. In contrast, the portion of function words produced contrary results, which in turn suggests that this feature might not constitute an effective test of the hypothesis. Second, it was found that the use of connectives was more salient in original English newspaper texts than translated English texts, being incompatible with the explicitation hypothesis. Third, as an indicator of translational normalization, lexical bundles were found to be more pervasive in translated texts than in non-translated texts, which is expected from and therefore support the normalization hypothesis. Finally, the standard deviations of both STTR and mean sentence lengths turned out to be higher in translated texts, indicating that the translated English newspaper texts were less leveled out within the same corpus group, which is opposed to what the leveling-out hypothesis postulates. Overall, the results suggest that not all four hypotheses may qualify for the label translation universals, or at least that some translational predictors are not feasible enough to evaluate the effectiveness of the translation universals hypotheses.

• Korean Journal of Heritage: History & Science
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• v.47 no.3
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• pp.108-127
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• 2014

Gangwha was a capital city of Goryeo, in spite of short-term occupation, where various national facilities such as palace stood in a row. Nevertheless, its historic importance has been undervalued owing to undiscovered palace. According to ${\ll}Goryeosa{\gg}$, palace in Gangwha was built in imitation of that of Gaegyeong. If it is true, the site of the old palace in Gaeseong as an original could give significant information for that of Gangwha. The distinct feature of Gaegyeong is that the palace was located in the west area of the centerline from north to south and pond lay in the east side. There is a mountain in the center of capital and two rivers runs along side the mountain. Gunggol at Gwancheong-ri is a best place where structural peculiarities of Gaegyeong can be applicable to Gangwha. There is an area of celadon distribution and is some topographic similarities such as central mountain, two rivers are quite similar. It is assumable that excavation result of no. 405 Gwancheongri reflects the function of east pond and thoroughfare responds to main street from north to south of Gaegyeong. After all the analysis from archaeological information, old maps, cadastral maps, topographic similarities and so on, Gunggol at Gwancheong-ri within an arc shape road is a most suitable place as palace in Gangwha.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.4
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• pp.215-222
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• 2019

The heat conduction problem with discontinuous material coefficients generally consists of the conservative equation, boundary condition, and interface condition, which should be additionally satisfied in the solution procedure. This feature often makes the development of new numerical schemes difficult as it induces a layered singularity in the solution fields; thus, a special approximation is required to capture the singular behavior. In addition to the approximation, the construction of a total system of equations is challenging. In this study, a wedge function is devised for enriching the approximation, and the interface condition itself is embedded in the moving least squares(MLS) derivative approximation to consistently satisfy the interface condition. The heat conduction problem is then discretized in a strong form using the developed derivative approximation, which is named as the interface immersed MLS difference method. This method is able to efficiently provide a numerical solution for such interface problems avoiding both numerical quadrature as well as extra difference equations related to the interface condition enforcement. Numerical experiments proved that the developed numerical method was highly accurate and computationally efficient at solving the heat conduction problem with interfacial jump as well as the problem with a geometrically induced interfacial singularity.

• The Journal of the Acoustical Society of Korea
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• v.40 no.2
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• pp.139-147
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• 2021

This paper introduces and implements a Sound Event Detection (SED) system based on weakly-supervised learning where only part of the data is labeled, and analyzes the effect of parameters. The SED system estimates the classes and onset/offset times of events in the acoustic signal. In order to train the model, all information on the event class and onset/offset times must be provided. Unfortunately, the onset/offset times are hard to be labeled exactly. Therefore, in the weakly-supervised task, the SED model is trained by "strongly labeled data" including the event class and activations, "weakly labeled data" including the event class, and "unlabeled data" without any label. Recently, the SED systems using the mean-teacher model are widely used for the task with several parameters. These parameters should be chosen carefully because they may affect the performance. In this paper, performance analysis was performed on parameters, such as the feature, moving average parameter, weight of the consistency cost function, ramp-up length, and maximum learning rate, using the data of DCASE 2020 Task 4. Effects and the optimal values of the parameters were discussed.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.22 no.4
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• pp.827-839
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• 2012

A cell phone is very close to the user and therefore should be considered in digital forensic investigation. Recently, the proportion of smartphone owners is increasing dramatically. Unlike the feature phone, users can utilize various mobile application in smartphone because it has high-performance operating system (e.g., Android, iOS). As acquisition and analysis of user data in smartphone are more important in digital forensic purposes, smartphone forensics has been studied actively. There are two way to do smartphone forensics. The first way is to extract user's data using the backup and debugging function of smartphones. The second way is to get root permission, and acquire the image of flash memory. And then, it is possible to reconstruct the filesystem, such as YAFFS, EXT, RFS, HFS+ and analyze it. However, this methods are not suitable to recovery and analyze deleted data from smartphones. This paper introduces analysis techniques for fragmented flash memory pages in smartphones. Especially, this paper demonstrates analysis techniques on the image that reconstruction of filesystem is impossible because the spare area of flash memory pages does not exist and the pages in unallocated area of filesystem.