• Journal of Korean Neurosurgical Society
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• v.64 no.6
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• pp.995-1003
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• 2021

Objective : People are living longer and the elderly population continues to increase. The incidence of degenerative spinal diseases (DSDs) in the elderly population is quite high. Therefore, we are facing more cases of DSD and offering more surgical solutions in geriatric patients. Understanding the significance and association of frailty and central sarcopenia as risk factors for spinal surgery in elderly patients will be helpful in improving surgical outcomes. We conducted a retrospective cohort analysis of prospectively collected data to assess the impact of preoperative central sarcopenia, frailty, and comorbidity on surgical outcome in elderly patients with DSD. Methods : We conducted a retrospective analysis of patients who underwent elective spinal surgery performed from January 1, 2019 to September 30, 2020 at our hospital. We included patients aged 65 and over who underwent surgery on the thoracic or lumbar spine and were diagnosed as DSD. Central sarcopenia was measured by the 50th percentile of psoas : L4 vertebral index (PLVI) using the cross-sectional area of the psoas muscle. We used the Korean version of the fatigue, resistance, ambulation, illnesses, and loss of weight (K-FRAIL) scale to measure frailty. Comorbidity was confirmed and scored using the Charlson Comorbidity Index (CCI). As a tool for measuring surgical outcome, we used the Clavien-Dindo (CD) classification for postoperative complications and the length of stay (LOS). Results : This study included 85 patients (35 males and 50 females). The mean age was 74.05±6.47 years. Using the K-FRAIL scale, four patients were scored as robust, 44 patients were pre-frail and 37 patients were frail. The mean PLVI was 0.61±0.19. According to the CD classification, 50 patients were classified as grade 1, 19 as grade 2, and four as grade 4. The mean LOS was 12.35±8.17 days. Multivariate stepwise regression analysis showed that postoperative complication was significantly associated with surgical invasiveness and K-FRAIL scale. LOS was significantly associated with surgical invasiveness and CCI. K-FRAIL scale showed a significant correlation with CCI and PLVI. Conclusion : The present study demonstrates that frailty, comorbidity, and surgical invasiveness are important risk factors for postoperative complications and LOS in elderly patients with DSD. Preoperative recognition of these factors may be useful for perioperative optimization, risk stratification, and patient counseling.

• Mood & Emotion
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• v.16 no.3
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• pp.140-151
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• 2018

Objectives : The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. Methods : Sixty six female patients with major depressive disorders were enrolled from a six-week, randomized prospective open-label multi-center study. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day). Montgomery Asberg Depression Rating Scale, 17-item Hamilton Depression Rating scale (HAM-D17), Iowa Fatigue Scale, Drug-Induced Extrapyramidal Symptoms Scale, Psychotropic-Related Sexual Dysfunction Questionnaire scores, and Clinical Global Impression-Severity (CGI-S) were obtained at baseline and after one, two, four, and six weeks. Changes on individual items of HAM-D17 were assessed as well as on composite scales (anxiety, insomnia and drive), and on four core subscales that capture core depression symptoms. Results : Overall, both treatments improved depressive symptoms, without causing serious adverse events. There were significant differences in the HAM-D17 total score (p=0.046) and CGI-S (p=0.004), between aripiprazole and bupropion augmentation, favoring aripiprazole over bupropion. Aripiprazole revealed significantly greater effect size in depressed mood (p=0.006), retardation (p=0.005), anxiety psychic (p=0.032), and general somatic symptom (p=0.01). Conclusion : While both treatments were effective, results of this study suggested that aripiprazole may be preferable, in treating general and core symptoms of female depression.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.2
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• pp.154-165
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• 2002

Objectives : The purpose of this study was to identify characteristics of depression in cancer patients treated with chemotherapy. Methods : Subjects were 37 cancer inpatients of oncology in Yeungnam university hospital. BDI and ZDS were done and HDS was performed through semistructured interview. Results: 1) There were no significant differences of depression scale score according to sex, education, religion, marital status. 2) The mean scores of BDI, ZDS and HDS in 37 cancer patients were 18.27${\pm}$7.73, 36.51${\pm}$10.82, 15.14${\pm}$6.60, respectively. 3) HDS, ZDS scores were significantly higher in other cancer group receiving high dose chemotherapy. 4) Item score for depressed mood, diurnal variation(p<0.001), dissatisfaction(p<0.01), physical anxiety, decreased libido, sleep disturbance(p<0.05) were significantly higher in other cancer group than others. 5) Eight patients were diagnosed as having major depressive disorder, 11 as adjustment disorder, and 18 patients had no axis I diagnosis. 6) In major depressive disorder group, the score of the depressed mood item in ZDS was high (p<0.05). HDS item score for depressed mood, work difficulty, anxiey(p<0.001), psychomotor retardation(p<0.01) were significantly higher in major depressive disorder group. 7) In patients with adjustment disorder, ZDS item score of constipation(p<0.001), fatigue, anorexia (p<0.01), emptiness, sleep disturbance, dissatisfaction, weight loss(p<0.01) were high. HDS item score of hypochondriasis(p<0.01), agitation(p<0.01), fatigue, decreased libido(p<0.05) were significantly higher in adjustment disorder group. Conclusion : Some psychiatric disorders, such as adjustment disorder and major depressive disorder were common in the cancer patients in chemotherapy. Psychiatric intervention will increase compliance of cancer treatment and improve the quality of life. This study suggests that it would be important to consider the nature of somatic symptoms in diagnosing depression in cancer patients.

• The Journal of Korean Academic Society of Nursing Education
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• v.3 no.2
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• pp.214-225
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• 1997

Sleep is an inevitable part of human existence and a part of the dynamic quality of life. The purpose of this study is to explore sleep pattern changes and related factors of patients hospitalized. The participants are 158 patients hospitalized in one general hospital. The questionnaire was developed by modification of VSH sleep scale (1987). Open question was used for research of related factors. $SPSS/PC^+$ are utilized for data analysis. The results are as follows ; There is significant difference before and after admission in the sleep disturbance. There is retroverse significant difference before and after admission in the sleep effectiveness. There is no significant difference between two groups in the nap supplementation. The patients reported pain by reason of sleep latency and mid-sleep awakening and noise due to early awakening. The reasons for lack of sleep were pain and noise. The method for overcoming their sleep disturbance, most of the subjects waited with closed eyes, imaged by themselved and took medicate sleeping pills. Discomfort manifested in the case of insufficient steepness was fatigue, headache and aggressiveness.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.132-137
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• 2005

This paper addresses what amount of whole-body vibration is exposed to pilots of UH60 helicopters during flight. To measure the whole-body exposed from the feet and seat, the 12-axis vibration measurement system was used. It enables simultaneous measurement of vibration exposure from the body contact area of the feet, hip and back. The measured 12-axis vibration signals are exploited to the comfort level of UH60 helicopters during flight. It is shown that the evaluated ride value is close to $0.74{\sim}0.79m/s^2$ and that it is equivalent to the semantic scale of 'fairly uncomfortable'. To assess the health effects of whole-body vibration exposed to pilots of UH60 helicopters during their flight, the rms-based and VDV(vibration dose value)-based evaluation results of measured four-axis vibration signals are shown in this work. The fatigue-decreased proficiency limit, whose level is half of the exposure limit, is expected to come after the two-hour flight. The exposure limit is shown to reach after the 10-hour flight.

• The Journal of Korean Physical Therapy
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• v.19 no.5
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• pp.87-96
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• 2007

Purpose: It remains controversial for the effect of daily functioning and quality of life on therapeutic exercise after stroke. The purpose of this study was to describe the effects on daily functioning and QOL. Methods: Outcome measures of daily functioning included, such as the Functional Independence Measure (FIM), Barthel index. Outcome measures of QOL included, such as Stroke Impact Scale(SIS) and the Medical Outcomes Study short-form 36-item questionnaire(SF-36). Results: 125 stroke patients were recruited, who were in or outpatients. The average age was 55.4 years. 64.8% were male. The mean Bathel index and FIM score was 63.7 and 87.5. The mean SIS score were higher in communication and mean SF-36 score were higher in physical pain. In/out patients are associated with SIS (communication, emotion) and SF-36(social function, energy or fatigue). Sex are associated with SF-36 (physical function). Other disease state are associated with SIS(hand function) and SF-36 (physical function). Paralysis portion are associated with SIS(communication, daily activity). Barthel index are associated with SIS(communication, mobility) and SF-36(social function, physical function, role limits due to emotional problems). Conclusion: These findings may provide the useful with rehabilitation professionals, who specilalized in the importance of QOL in designing treatment modalities.

• Journal of Korean Physical Therapy Science
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• v.4 no.2
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• pp.383-390
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• 1997

The purpose of this study is the evaluation of the degree of post injection soreness, symptom duration, factor and autonomic symptoms after trigger point injection in patients with trigger points. We devided the subjects of the study into four groups Such as, only dry needling, needle-TENS, with massage-stretch, massage-stretch only, including 100 patients, and measured the visual analog scale before treatment and after treatment. Before treatment, The VAS mean scores were $6.2{\pm}1.03$ in needle-TENS with massage-stretch group ; $6.2{\pm}1.75$ in needdle-TENS group, and $6.3{\pm}1.85$ in dry needling group, and $6.8{\pm}1.03$ in massage-stretch group. In post injection 3rd day, The VAS mean score were $0.9{\pm}1.78$ in needling-TENS with massage-stretch group, $1.1{\pm}1.52$ in needling-TENS group, $1.7{\pm}1.10$ in dry needling group, and $3.9{\pm}3.01$ in massage-stretch group. As for a causative factor of activities for trigger were overload with 37.0%, overwork with 35.0% and fatigue with 13.0%. Symptoms for trigger were tenderness with 28.0%, numbness and tingling with 24.0%. ROM limit with 17.0% and tightness with 17.0%. As a result, needling-TENS with massage-stretch group showed less soreness and effect than other group.

• 대한상한금궤의학회지
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• v.8 no.1
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• pp.121-143
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• 2016

Objective : This study is to report 4 Eumyangyeokchahunobok-byung cases diagnosed and treated according to newly hypothesized Eumyangyeokchahunobok-byung definition based on Shanghanlun disease pattern identification diagnostic system. Methods : We analyzed 4 clinical cases diagnosed with Eumyangyeokchahunobok-byung and treated by herbal medicine, which included in Eumyangyeokchahunobok-byung chapter of Shanghanlun according to newly hypothesized definition. Results : Dermatology Life Quality Index decreased from 25 to 10 on first patient, dizziness handicap inventory decreased from 64 to 2 on second patient, dizziness handicap inventory also decreased from 56 to 2 on third patient, and fatigue severity scale decreased from 7 to 2 on fourth patient. Conclusions : Not only all the patients' chief complaints relieved but their other clinical problems such as allergic rhinitis, body pain, constipation, reflux esophagitis also improved. These results highly insist that there is quite a possibility that Eumyangyeokchahunobokbyung means various diseases caused by reversed sleep cycle.

• KIEAE Journal
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• v.4 no.1
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• pp.11-20
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• 2004

Innovative daylighting systems in buildings in various climatic zones around the world have been developed under the IEA SHC Task21. The performance assessment were obtained by monitoring the most systems using full-scale test model rooms or actual buildings under real sky conditions. This study aims to analyze the configuration and monitoring system of the nine Mock-up models of the IEA SHC Task21 comparatively. For the purpose, the geometry of the test rooms (length, width, height, window area, glazed area and occupied), reflectance of walls, floor and ceiling, transmittance of glazing (transmittance for hemispherical irradiation, normal irradiation and U-value) were compared. And equipment for measurement (manufacturer, range, calibration, maximum calibration error, cosine response error, fatigue error), and data acquisition system (manufacturer, type, number of differential analogue input channels, A/D converter resolution in bits, data acquisition software) were also analyzed comparatively. Some findings of these experimental methodology of standard monitoring have been proven to be a valuable one for future assessment of advanced daylighting systems in our country.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.5
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• pp.740-745
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• 1987

For the prediction of the crack growth initiation from a blunt notch or a precrack in a prestrained material under plane strain tension and small-scale yielding conditions, a microscopic fracture criterion is proposed in terms of the crack tip opening displacement(COD) needed for the attainment of fracture strain at a microstructural distance. Smooth blunting of a crack tip with an initial root radius is assumed, and strain distributions on the crack-line axis are calculated at each deformation stage until the distributions against an original distance normalized to the COD are insensitive to an initial root radius. This case of no initial-root-radius effect is taken as for a sharp crack tip, on which the criterion is applied to determine the characteristic length of material from a critical COD for a fatigue-precracked specimen. The predicted COD at the fracture initiation from a crack with an initial root radius or a prestraining shows reasonable agreement with experimental values.