• Asian-Australasian Journal of Animal Sciences
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• 제13권4호
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• pp.506-510
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• 2000

This experiment was to determine the usefulness of gum safflower phospholipid as a feed ingredient. Forty female broiler chicks were divided into four groups and fed experimental diets containing following fats and oils; beef tallow (Tallow), the blend of safflower oil and palm oil (SP-oil), gum rapeseed phospholipid (Rap-PL), or gum safflower phospholipid (Saf-PL) for 21days. There were no differences in growth performances among the treatments. Abdominal fat weight tended to be reduced in the chicks fed. phospholipids. The activity of hepatic acetyl-CoA carboxylase was significantly reduced in the Rap-PL and Saf-PL as compared to that of Tallow. Feeding dietary phospholipids resulted in a slight reduction in total fat and triglyceride contents in the breast and thigh muscles. In addition, total fat and triglyceride contents in the thigh muscle were significantly decreased by dietary Saf-PL as compared to those of Tallow. These results suggested that dietary gum phospholipids, either from rapeseed or safflower, had desirable effects of lowing abdominal and muscle fats, and could be used as a feed ingredient for broiler diets.

• 한국식품영양학회지
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• 제26권4호
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• pp.615-619
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• 2013

Obesity is the most common nutritional disorder in the developed world and has become a global epidemic in recent years. In this study, Zanthoxylum planispinum extracts (ZPE) were evaluated on the effect on inhibition of pancreatic lipase and lipid metabolism by oral treatment for 2 months in high-fed diet obesity-induced Balb/c mice. The ZPE showed pancreatic lipase inhibitory activity with $IC_{50}$ of $0.3{\mu}g/ml$. No significant difference in feed intake was observed among the groups. The high-fat diet-treated Z. planispinum extracts groups (HFD+ZPE, 100mg/kg) significantly decreased body weight compared to the high-fat diet vehicle groups (HFD, p<0.05). The high-fat diet-treated Xenical$^{(R)}$ groups (HFD+Xenical, n=10, 30mg/kg) also showed a significant reduction of body weight compared to HFD (p<0.05). Biochemical parameters (triglyceride, total cholesterol, and high-density lipoprotein cholesterol) in HFD plus ZPE diet groups were significantly lower than those of the HFD groups (p<0.05). These results indicated that ZPE more effectively suppressed the effects of HFD on body fat gain with the inhibitory effect on pancreatic lipase.

• 대한지역사회영양학회지
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• 제8권6호
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• pp.986-992
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• 2003

This study was performed to investigate the effects of a levan diet on the body fat accumulation and serum lipid composition of 29 Korean women over a period of up to 12 weeks (n=13 for the control group, n=16 for the levan group). The subjects ate an uncooked diet (6 g) with 400$m\ell$ of tap water twice a day. The mean body weight and height measurements of the subjects (levan group) at the outset were 66.0$\pm$8.8kg and 156.7$\pm$5.3cm, respectively. The subjects showed a significant reduction in weight, body fat mass, anthropometric measurements and skinfold thickness during the experimental period. The waist hip ratio (WHR) was 0.88$\pm$0.03 at the outset, and fell to 0.82$\pm$0.05 after 4 weeks. The intake of levan was also influenced on the levels of serum Fe, leptin, lipoprotein lipase, HDL-cholesterol, LDL-cholesterol, and triglyceride. The serum glucose levels were within the normal range during the experimental period. The initial serum triglyceride level was 121mg/dl, but fell to 103mg/dl after 4 weeks of levan supplementation. The current study demonstrates that a levan diet is effective in controlling weight, body fat, HDL-cholesterol, LDL-cholesterol, and triglyceride levels.

• 한국임상보건과학회지
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• 제7권2호
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• pp.1318-1324
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• 2019

Purpose. The study was conducted to find out the effects that women in their 20s with abdominal obesity can get from sling-based flanks. Methods. The study used In-Body to determine the weight and body fat rate of women in their 20s who were overweight at H University and used a tape measure to measure the circumference of the abdomen. Plank exercise using slings to reduce weight, body fat and abdominal circumference led to muscle stabilization and abdominal obesity reduction. The collected data were analyzed using the SPSS ver. 23.0 statistics program. Results. The results of the study showed statistically significant differences in the weight, body fat rate and abdominal circumference of the subjects before and after intervention. Conclusions. Steady abdominal muscles exercise help stabilize the abdomen, reduce abdominal body fat rate, and are effective in managing obesity.

• Food Science and Biotechnology
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• 제18권3호
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• pp.649-654
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• 2009

This study was designed to evaluate the effects of high-carbohydrate (HC) or high-fat (HF) diet with hydroxycitric acid (HCA)-containing Garcinia cambogia in rats. Seventy male Sprague-Dawley rats were randomly divided into 7 groups and raised with experimental diets containing different HCA levels (0, 1.6, and 3.2%) and calorie sources (carbohydrate, fat) for 8 weeks. Energy intake was significantly reduced in rats fed a HC diet with HCA compared to the HC diet without HCA. Body weight gain was significantly reduced in HCA groups. In the diet groups, plasma total lipid and triglyceride (TG) levels of the HCA groups were significantly lower than those of the group without HCA. There were no significant differences in energy intake and plasma lipid profile in HF groups. These results suggest that HC diet with HCA was more effective in the reduction of energy intake, body weight gain, and plasma lipid contents than those of HF diet with HCA.

• 생명과학회지
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• 제29권12호
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• pp.1351-1357
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• 2019

본 연구는 동물성 지방 대체제로서 식물성유 유화물인 올리브유(OPP), 대두유(SPP) 및 카놀라유(CPP) 유화물을 첨가한 돈육 패티의 품질 특성을 조사하였다. OPP, SPP 및 CPP의 수분 함량이 CON보다 높고, 지방 함량은 낮았다. OPP, SPP 및 CPP는 CON보다 보수력, 수율, 수분 보유율, 지방 보유율이 높았으며, 직경 감소율과 수축율은 낮았다. 가열 전후의 돈육 패티의 백색도와 적색도는 CON이 OPP, SPP 및 CPP보다 높고, 가열 전 돈육 패티의 황색도는 OPP가 가장 높았다. 돈육 패티의 포화지방산은 palmitic acid가 가장 많이 함유되어 있었다. 불포화지방산은 CON (42.84%), OPP (65.41%), CPP (48.63%)의 경우 oleic acid가 가장 많았으며, SPP는 linoleic acid (41.17%)가 가장 많이 함유되어 있었다. 돈육 패티의 불포화지방산 함량은 식물성유 유화물의 대체로 증가하였다. 경도, 응집성 및 저작성은 시료들 사이에 차이가 없었으며, 탄력성은 CON보다 OPP, SPP 및 CPP가 높았다. 맛, 풍미, 전체적인 기호도는 OPP 및 CPP가 CON 및 SPP보다 높게 나타났다. 따라서 식물성유를 겔화시켜 동물성 지방을 대체하면 이화학적·관능적 특성이 향상되고 지방산 조성이 개선되어 소비자들이 요구하는 건강에 유익한 저지방 육제품의 제조가 가능하다.

• 한국식품과학회지
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• 제36권6호
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• pp.1014-1019
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• 2004

김치유산균추출물의 비만억제 및 지질 저하 효과를 20%(w/w) 고지방식이를 섭취시킨 횐 쥐에서 살펴보았다. 제한식이를 하였음에도 불구하고 HFD의 체중은 ND에 비해 약 50%증가 하였고, HFK10 및 HFK20에서는 HFD에 비해 각각 13%그리고 15%(p<0.01) 감소하였다. HFD의 복부지방의 함량은 ND에비해 98% 증가하였고(p<0.01), HFK10 및 HFK20에 서 각각 42%, 48% 유의적으로 감소하여(p<0.01) 체중 저하 효과 보다 복부지방 축적을 억제하는 효과가 더 높은 것으로 나타났다. 혈장 중성지방의 농도는 HFD가 ND에 비해 약 55% 증가하였고(p<0.01), HFK10 및 HFK20은 HFD에 비해 26%, 및 35% 농도 의존적으로 감소하였다(p<0.01). 혈장 총 콜레스테롤 농도 역시 HFK10 및 HFK20에서 농도의존적으로 유의적인 감소를 보였고(p<0.01) LDL 농도는 HFD가 ND보다 61% 정도 증가하였고(p<0.01), HFK10 및 HFK20에서 약 8%, 33%감소하여(p<0.01)총 콜레스테롤 보다 LDL의 감소가 더 현저하였다. HDL은 증가하여 김치유산균추출물의 첨가에 의한 지질 개선 효과가 관찰되었다. 김치 유산균 추출물의 간 기능 개선 효과는 고지방 식이에 의해 유발된 지방간 현상으로 정상대조군에 비해 상승되었던 혈장 AST 및 ALT 활성이 감소됨으로서 관찰되었다. 분변의 지방농도를 HFD와 HFK10 및 HFK20간에 비교하였을 때 중성지방 농도는 각 62%와 111% 정도 현저하게 증가하였고, 콜레스테롤 농도는 HFK20에서 약 31% 정도 증가하였다(p<0.05). 이상의 결과에서 사균의 형태인 김치유산균 추출물은 비만을 억제하고 혈장 지질을 저하시키는 효과가 있음이 확인되었으며, 간 기능 보호효과도 확인되었다. 이러한 김치유산균 추출물의 효과는 장내에서 지방의 흡수를 억제하기 때문으로 생각된다.

• 한방비만학회지
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• 제24권1호
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• pp.87-93
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• 2024

Objectives: Obesity is a globally prevalent public health issue. Hence, there is a need for the development of safer and more effective anti-obesity drugs. Lythrum salicaria, a traditional medicinal herb used for centuries, has been reported to improve lipid metabolism and fat accumulation. It also has a low toxicity profile. Therefore, its potential as a functional ingredient in health functional foods needs to be evaluated. Methods: In this randomized, double-blind, placebo-controlled clinical trial, 90 participants will be randomly assigned to either the experimental or control group. Each subject will orally receive L. salicaria extract (1,350 mg/day) (500 mg L. salicaria+850 mg lactose as vehicle) or lactose (1,350 mg/day) as a hard capsule formula for 84 days (12 weeks). The primary outcome will be body fat mass (kg), which will be assessed using dual-energy x-ray absorptiometry (DXA) (performed only at visits 2 and 4). Secondary outcomes include body mass index, body weight, waist-to-hip ratio, body fat percentage (%) measured using DXA, lean body mass (kg) measured using DXA (assessed only at visits 2 and 4), lipids (total cholesterol, triglyceride, high-density lipoprotein cholesterol, and calculated low-density lipoprotein cholesterol), free fatty acid, high sensitivity C-reactive protein, adiponectin, and leptin. Conclusions: This protocol will be implemented after approval of Institutional Review Board of Pusan National University Korean Medicine Hospital (approval number: PNUKHIRB-2022-08-002) and registration with the Korean National Clinical Research Information Service (CRIS) (CRIS-KCT0008060). The results of this trial will provide potential of L. salicaria as a new anti-obesity functional food with fat-reducing effects and low toxicity.

• 한방비만학회지
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• 제1권1호
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• pp.57-62
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• 2001

Objectives : This study was designed to investigate the effects of Fangfengtongsheng-san on obese patients. Materials and Methods : 20 patients that take Fangfengtongsheng-san during 3weeks at obesitic clinic, Conmaul Oriental Hospital from June 2000 to October 2000 were selected for this study. Results : In the change of body composition, the reduction of weight was $2.46{\pm}1.31\;kg$, the reduction of percent body fat was $1.34{\pm}0.84%$, the reduction of 8MI was $0.96{\pm}0.17$. Conclusion: This study shows that Fangfengtongsheng-san is effective on weight reduction.

• 한국조리학회지
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• 제23권6호
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• pp.173-183
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• 2017

Conditions related to body composition and aging, such as osteopenic obesity, sarcopenia/ sarcopenic obesity, and the newly termed osteosarcopenic obesity(triad of bone, muscle and adipose tissue impairment), are beginning to gain recognition. Currently, it has begun to attract the attention of scholars from all over the world, however, for this disease, it still needs a more clear understanding and perception. Therefore, this article considered the osteoporosis, muscle depression, and obesity, these diseases as a gate to study the relationship among muscle, bone, and fat. In addition, in the aging process, the formation of IGF-cortisol, testosterone, and estrogen is sensitive. These hormones can not only absorb muscle protein metabolism, but also affect alienation. The decrease in IGF-cortisol in the elderly resulted in increased visceral fat, decreased muscle mass and bone mineral density, and then affected decreased skeletal muscle atrophy and decreased quality. The reduction of skeletal muscle quality and strength and increase body fat affected the adipose tissue to produce inflammatory cytokines, thereby reduced skeletal muscle, promoted cardiovascular disease, metabolic syndrome and insulin resistance in chronic diseases. Almost all chronic inflammatory diseases were associated with bone, muscle and fat. These mechanisms were complex and interrelated. Inflammation reduces bone formation, increases fat and reduces muscle mass. And thus not only had a significant impact on the motor system, but also made the incidence increase of fracture, osteoporosis, fragile syndrome, fall, osteomalacia and other bone disease. This article aimed to start from the interaction between the muscles and bones of the elderly, extended to obesity, muscle deficiency, osteoporosis and other diseases, finally, from a nutritional point of view, to discuss how to treat osteoporosis obesity.