• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2247-2257
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• 2024

To investigate the impact of the recently released pediatric reference voxel phantoms (0-, 1-, 5-, 10-, 15-year-old males and females) of the International Commission on Radiological Protection (ICRP) on organ dose estimates for radioactive iodine (RAI) treatment in pediatric patients, we calculated and analyzed pediatric-specific iodine131 S values (r_T ← thyroid) for the 30 radiosensitive organs by conducting Monte Carlo simulations using the Geant4. The gender dependency in the S values was frequently seen for the 15-year-old phantoms with higher S values of female than male. In addition, the age dependency in the S values was observed for most target organs; that is, the S values tend to decrease for older ages (e.g., ~120 times for the gonads between the adult and newborn) due mainly to the inter-organ distances generally longer for older ages. Moreover, we observed that the iodine-131 S values tend to be significantly greater by up to ~145.5 times than those of the stylized phantoms that have been widely used for organ dose estimates of pediatric RAI patients. We believe that the pediatric-specific iodine-131 S values (r_T ← thyroid) of the ICRP pediatric reference voxel phantoms should be beneficial to improve the dosimetry of pediatric RAI patients.

• Journal of Korean Home Economics Education Association
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• v.22 no.3
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• pp.95-116
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• 2010

The purpose of this study is to explore the role of Home Economics Education for low fertility Aged Society. Hence home economics educational contents for low fertility Aged Society was estsblished extracting the contents from both Revised 2007 Home Economics Curriculum and government. policy for low fertility Aged Society. Also home economics educational contents for low fertility Aged Society("Home Economics Class for both parents and Children") implemented in Healthy Family Support Center. The main results of the study are as follows. Firstly, Home Economics Education for low fertility Aged Society should be emphasized with the contents such as marriage of one's choice, family life reinforcement, healthy family culture and neighborhood living together. Secondly, the goal of home economics education is very similar to the action plans of Saeromaji Project 2010 which are 'social responsibility reinforcement for marriage, birth and child rearing', 'balancing family and work', 'family-friendly culture' and 'security for the aged with health and care'. It has also much in common with the project plans by Seoul Metropolitan Office of Education 'family-friendly culture and filial duty education reinforcement', 'school education reinforcement regarding Low Fertility-Aged Society' and 'values education reinforcement for gender equality society'. Thirdly, "Home Economics Class for both parents and Children" applied in Healthy Family Support Center in Jung-gu, Seoul. This ensures home economic education can play a leading role in the social education filed.

• Journal of Animal Science and Technology
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• v.53 no.1
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• pp.1-6
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• 2011

This simulation study was performed to investigate the accuracy of the estimated breeding value by using genomic information (GEBV) by way of Bayesian framework. Genomic information by way of single nucleotide polymorphism (SNP) from a chromosome with length of 100cM were simulated with different marker distance (0.1cM, 0.5cM), heritabilities (0.1, 0.5) and half sibs families (20 heads, 4 heads). For generating the simulated population in which animals were inferred to genomic polymorphism, we assumed that the number of quantitative trait loci (QTL) were equal with the number of no effect markers. The positions of markers and QTLs were located with even and scatter distances, respectively. The accuracies of estimated breeding values by way of indicating correlations between true and estimated breeding values were compared on several cases of marker distances, heritabilities and family sizes. The accuracies of breeding values on animals only having genomic information were 0.87 and 0.81 in marker distances of 0.1cM and 0.5cM, respectively. These accuracies were shown to be influenced by heritabilities (0.87 at $h^2$ =0.10, 0.94 at $h^2$ =0.50). According to half sibs' family size, these accuracies were 0.87 and 0.84 in family size of 20 and 4, respectively. As half sibs family size is high, accuracy of breeding appeared high. Based on the results of this study it is concluded that the amount of marker information, heritability and family size would influence the accuracy of the estimated breeding values in genomic selection methodology for animal breeding.

• Journal of the Korean Home Economics Association
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• v.27 no.2
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• pp.133-148
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• 1989

This study attempts of analyze empirically the living status of the elderly in Korea by finding out the problems of it in the family and by clarifying the influences of the family environmental variables and the values on the adjustment of the aged. To carryout the aim of this study, the causes and the patterns of the problems for the aged had been found out through the review of literature. Based on them the questionnaire was prepared including the questions of the values, family environmental vriables as well as the degree of satisfaction of thier liver and the extent of life interchange. The former variables were taken as independent and the latter were taken as dependent variables, so that the relationship between the two variables could be exemplified. The 400 aged over 60 living in Seoul and the other cities were selected through the purposive sampling and interviewed. The answers of the 376 respondents, 94% of the sample, were analyzed for this study. The following results have been found out through the various statistical analysis such as frequency distribution, chi-square test, pearson's correlation, analysis of variance and cluster analysis. At first, the results from the examination of the frequency distribution regarding the living status of the aged are; I) sixteen percent of the respondents living with their married offspring were receiving economical support, though they pointed out the problems of the extended family are the inconveniences with their children (60%) and simpleness (20%) of their livers. It seems that the aged in Korea are poor and have negative opinion on the relationship with their offspring even if they live in the same house. Secondly, it has been found out that the family environmental variables, especially such as sex, occupation, residence, education, level, living ability and the family type, play and important role not only on the degree of satisfaction of their liver but also on the extent of interchange of their lives. However, the variables such as religion and whether the spouse is alive or not do not play and important role. Thirdly, the reported main reasons of their delightness were healthy life (1.87%), the well-being of their offspring (2.08%), the spouse's long life (3.38%), religious activity (5.05%), the hobby activity (4.31%) and the participation in the social activity (5.05%). While, they mainly concern about the illness (1.98%), offspring (2.00%), econmic difficulties (3.39%), inharmonious home (3.81%) and the despicable treatment (3.81%). The respondents wer classified into two groups, they are dependent and independent, using cluster analysis. Health, social activity, offspiring, religion, couple's long life among the factors which lead them to be delighted were turned out to be statistically signhificant at 0.01 significance level between the two groups. As far as their worrisome matters are concerned, health and economic difficulties were significantly different between the two groups. Fourthly, regarding the life interchange, it has been proved that there is a statistically significant differences betwwen the two groups in the economic and the emotional satisfaction, help for ordinary life, status in the family, subjective and objective relationship with offspring, but not in economic dependency and the activity status. Fifthly, it has been noted that there is a high correlation between the degree of life's satisfaction and the extent of life interchange. On the basis of the results mentioned above, it could be concluded taht; i) The majority of the aged in Korea are not economically active, and thus they live with their married offspring even of they have a negative opinion on the subjective relationship with them. This can be pointed out as the main problem of the aged and thus it needs to be studied further. ii) the environmental variables such as age, sex education level, family type and occuption (which can not be changed by their effrot) turned out to give an important effect on the extent of the life interchange among the aged. iii) The respondents who are identified as independent group have a higher degree of life satisfaction and family status than the group identified as defendent. Thus, it can be inferred that it is possible for them to adjust their life by making an effort to modify themselves. iv) The high correlation between the extent of life interchange and the degree of life satisfaction indicates that the elderly themselves can adjust in order to obtain the higher degree of life satisfaction. Therefore, the following suggestions are derived from this study. First of all, the aged should try to be psychologically independent. Second, they need to control themselves in order to achieve self-assurance. Third, the community have to prepare a program of self-development for the aged. Fourth, the social welfare policy that can solve the problem of illness and poverty of the elderly should be introduced, so that their minimum requirements can be satisfied.

• Journal of the Korean Society for Library and Information Science
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• v.46 no.3
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• pp.271-295
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• 2012

This study aims to extract and analyze the bibliotherapeutic values/situations of Korean folk-tales for multi-cultural families in Korea. By analyzing 27 stories in the Korean folk-tale picture book written in two languages(Korean & English), we can find out 5 kinds of situational analysis as follows: (1) There are more men than women by the biological sex factor, whereas there are more adults than younger persons by the biological age discrimination. (2) For the space concept, there are a lot of socially related stories in their surroundings. (3) In the vertical relationship, there are more conflict elements than in the horizontal one. (4) There are more helpers from the outside than in the inside circle for the solution of their problems. (5) As a story theme, greed, wisdom, belief and family component elements are greatly involved in the stories. Among their beliefs, there are a lot of wisdom and greed themes, while piety and royalty to parents and conflict against stepmothers are among the family components. All of these would be an archetype of Korean culture, which can play an important role not only to understand Korean lifestyle for the multi-cultural families, but also to learn and practice bibliotherapeutic values.

• Animal Bioscience
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• v.34 no.6
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• pp.975-984
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• 2021

Objective: Inbreeding depression of reproduction is a major concern in the conservation of native chicken genetic resources. Here, based on the successful development of strongly inbred (Sinb) and weakly inbred (Winb) Langshan chickens, we aimed to evaluate inbreeding effects on reproductive traits and identify candidate genes involved in inbreeding depression of reproduction in Langshan chickens. Methods: A two-sample t-test was performed to estimate the differences in phenotypic values of reproductive traits between Sinb and Winb chicken groups. Three healthy chickens with reproductive trait values around the group mean values were selected from each of the groups. Differences in ovarian and hypothalamus transcriptomes between the two groups of chickens were analyzed by RNA sequencing (RNA-Seq). Results: The Sinb chicken group showed an obvious inbreeding depression in reproduction, especially for traits of age at the first egg and egg number at 300 days (p<0.01). Furthermore, 68 and 618 differentially expressed genes (DEGs) were obtained in the hypothalamus and ovary between the two chicken groups, respectively. In the hypothalamus, DEGs were mainly enriched in the pathways related to vitamin metabolism, signal transduction and development of the reproductive system, such as the riboflavin metabolism, Wnt signaling pathway, extracellular matrix-receptor interaction and focal adhesion pathways, including stimulated by retinoic acid 6, serpin family F member 1, secreted frizzled related protein 2, Wnt family member 6, and frizzled class receptor 4 genes. In the ovary, DEGs were significantly enriched in pathways associated with basic metabolism, including amino acid metabolism, oxidative phosphorylation, and glycosaminoglycan degradation. A series of key DEGs involved in folate biosynthesis (gamma-glutamyl hydrolase, guanosine triphosphate cyclohydrolase 1), oocyte meiosis and ovarian function (cytoplasmic polyadenylation element binding protein 1, structural maintenance of chromosomes 1B, and speedy/RINGO cell cycle regulator family member A), spermatogenesis and male fertility (prostaglandin D2 synthase 21 kDa), Mov10 RISC complex RNA helicase like 1, and deuterosome assembly protein 1) were identified, and these may play important roles in inbreeding depression in reproduction. Conclusion: The results improve our understanding of the regulatory mechanisms underlying inbreeding depression in chicken reproduction and provide a theoretical basis for the conservation of species resources.

• Journal of Christian Education in Korea
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• v.68
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• pp.113-140
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• 2021

In today's family, it can be said that children's faith education is in a very difficult time. Moreover, faith education at home is urgently required during the COVID-19 pandemic. However, as society changes rapidly, families are also changing rapidly. As the current society became diversified and personalized, the family lost its educational function. In other words, it can be immediately said that faith education in Christian families has collapsed. The reason is that the problem of faith education in today's family lies in poor communication. Communication problems are becoming difficult for parents and children due to changes in values caused by individualism and capitalism, and as the difference between values and the generation of children widens. In addition, disconnection of dialogue at home due to the disconnection of culture between generations is an obstacle to faith education. It is urgent to restore the educational function of Christian families. When parents provide Christian faith education to their children, their children can grow up properly. Communication with children is desperately needed to restore the purpose and function of faith education at home. Communication between parents and children is an important factor influencing children's motivation for religious education. Parents and children's communication must be open and positive parenting attitudes need to be sufficiently motivated for faith education. In order to solve the immediate problem of the absence of faith education at home, an alternative will be proposed to restore faith education through communication between parents and children. First, the necessity of faith education at home will be discussed. Then communication at the beginning of faith education will be considered. And third, communication and methods at home to implement faith education will be presented. This study will serve as an opportunity to provide clues to restore and implement faith education in Christian families.

• The Journal of Korean Society for School & Community Health Education
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• v.11 no.1
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• pp.117-134
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• 2010

Background & Objectives: Recently, problems such as in-school violence of teenagers, gang fight, habitual drinking, smoking, running away from home and group isolation can be regarded as the most fundamental causes of teenagers' deviation. It is said that such fundamental causes are originated from their home, the base for the psychological and behavioral development. Methods: In this study, the data for 3,188 students studying in the 3rd grade at middle school, which have been obtained from the second year survey for the panel of the 2nd grade students in 2004 by to Korea Youth Panel Survey, have been used for the analysis of the study. Results: According to the result of the study, there seems to be no difference between two genders for differences of average values. Regarding the analysis of correlation coefficients between such related variables as domestic violence, self-control, self-worth, self-trust and family relationship (sociability), and teenagers' deviation, When variables increase, teenagers' deviation decreases. Regarding the relationship between domestic violence and teenagers' deviation, physical violence is more related than lingual violence. The relationship between self-control and teenagers' deviation is the highest. By studying the deviation of teenagers exposed to domestic violence and carrying out the regression analysis, physical violence influences, teenagers' deviation was greater. As self-control, self-worth and family relationship(sociability) increase, teenagers' deviation decreases. Regarding the analytic results of this study, the experience of domestic violence seems to influence teenagers' deviation greatly. Among various types of domestic violence, physical violence is analyzed to influence teenagers' deviation greatly. Self-control, self-worth and family relationship(sociability) increase, teenagers' deviation decreases. Conclusions: In order to prevent teenagers' deviation and decrease the second conviction rate, it is necessary to provide a method of decreasing the domestic violence. It is necessary for schools and local communities to provide social support for teenagers.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8221-8226
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• 2016

Background: Misreporting self-reported family history may lead to biased estimations. We used Bayesian methods to adjust for exposure misclassification. Materials and Methods: A hospital-based case-control study was used to identify breast cancer risk factors among Iranian women. Three models were jointly considered; an outcome, an exposure and a measurement model. All models were fitted using Bayesian methods, run to achieve convergence. Results: Bayesian analysis in the model without misclassification showed that the odds ratios for the relationship between breast cancer and a family history in different prior distributions were 2.98 (95% CRI: 2.41, 3.71), 2.57 (95% CRI: 1.95, 3.41) and 2.53 (95% CRI: 1.93, 3.31). In the misclassified model, adjusted odds ratios for misclassification in the different situations were 2.64 (95% CRI: 2.02, 3.47), 2.64 (95% CRI: 2.02, 3.46), 1.60 (95% CRI: 1.07, 2.38), 1.61 (95% CRI: 1.07, 2.40), 1.57 (95% CRI: 1.05, 2.35), 1.58 (95% CRI: 1.06, 2.34) and 1.57 (95% CRI: 1.06, 2.33). Conclusions: It was concluded that self-reported family history may be misclassified in different scenarios. Due to the lack of validation studies in Iran, more attention to this matter in future research is suggested, especially while obtaining results in accordance with sensitivity and specificity values.

• The Korean Journal of Malacology
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• v.29 no.2
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• pp.155-161
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• 2013

Cathepsins are lysosomal/cysteine proteases belong to papain family (C1 family) that is involved in intracellular protein degradation, antigen processing, hormone maturation, and immune responses. In this study, member of cathepsin family was identified from Manila clam (Mc-Cathepsin D) and investigated the immune response against brown ring disease (BRD) causing Vibrio tapetis challenge. The identified Mc-Cathepsin D gene encodes characteristic features typical for the cathepsin family including eukaryotic and viral aspartyl protease signature domain and two highly conserved active sites ($^{84}VVFDTGSSNLWV^{95}$ and $^{270}IADTGTSLLAG^{281}$). Moreover, MC-Cathepsin D shows higher identity values (-50-70%) and conserved amino acids with known cathepsin D members. Transcriptional results (by quantitative real-time RT-PCR) showed that Mc-Cathepsin D was expressed at higher levels in gills and hemocytes than mantle, adductor muscle, foot, and siphon. After the V. tapetis challenge under laboratory conditions, Mc-Cathepsin D mRNA was up-regulated in gills and hemocytes. Present study indicates that Mc-Cathepsin D is constitutively expressed in different tissues and potentially inducible when infecting BRD by V. tapetis. It is further suggesting that Mc-Cathepsin D may be involved in multiple role including immune response reactions against BRD.