• Journal of Family Resource Management and Policy Review
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• v.4 no.1
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• pp.59-68
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• 2000

Everyone lives in a home. We pursue happiness and the meaning of life through home life or family life. Home life, therefore, has an important meaning in the whole life, But home life can be sustained only through housework and wage labor. All human activities can be divided into two kinds of activities. The one has intrinsic value, the other has extrinsic value. Housework belongs to the activity with intrinsic value, but wage labor belongs to the activity with extrinsic value. In view of home life, housework has primary meaning, and wage labor has subsidiary meaning. In other words, wage labor is only means of home life. We mush not forget that important fact. But we cannot help thinking that nowadays people consider wage labor itself as an aim of life. It is said that we are achieving self-actualization through wage labor, but it is not ture. To tell the truth, most of us are experiencing self-alienation in job. We must recover the legitimate relation between housework and wage labor. Wage labor is means of home life, therefore it is on the extension line of housework. If we achieve happiness through home life, we must recognize that wage labor is only means of home life, not an end in itself.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.7 no.2
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• pp.316-331
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• 2000

This study was conducted using a descriptive correlational survey design to identify how patients with chronic low-back pain perceived family function and to examine the relationship between family function and depression. The participants of the study were 116 patients with chronic low-back pain patient who were having follow-up treatment in a local pain clinic, located in Daegu. A structured questionnaire was filled out participants themselves and the structured interview was given during January and February, 2000. The data collection instrument were FACE II-Korean version and Beck's Depression Inventory(1983). The data collected were analysed using mean, standard deviation(SD), t-test, F-test, Duncan test and Pearson correlation coefficient, done with SAS. The results are as follows; 1. The mean of the respondents' perceived family function was 3.47, with emotional bonding at 3.61, acceptability and sharing at 3.61, participation at 3.23, negotiation and satisfaction at 3.24 and responsibility and expectation at 3.76. 2. The mean of the respondents' perceived depression was $17.53{\pm}8.76$. 3. There was significantly negative correlation between family function and depression(r=-0.4817, p=.0001). 4. Research variables included demographic characteristics and showed that subjects who were aged 65 years or older showed significantly lower scores in patient's perceived family function than those who were aged 45 years or below(p=.0502). Perceived family function of females respondents were significantly lower than males(p=.0026). The illiterate showed significantly lower scores than other groups(p=.0001). Respondents with spouse and extended family tended to show significantly higher scores than those who were living with spouse only or by themselves alone(p=.0091). Those who had higher income showed significantly higher scores than in the lower income group(p=.0001). 5. For family function regarding pain characteristics, those who reported severe pain-related daily activity impediments showed significantly lower scores in family function than others with less pain(p=.0357).

• The Korean Journal of Health Service Management
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• v.6 no.1
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• pp.231-245
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• 2012

This study was focused on experience of adult offsprings with disabled parents, and thereby on the evaluation of their family-of-origin environment. Adult offsprings's experience and understanding of the evolution in terms of subjects were explored. This study reviewed the effects of the family-of-origin environment and the analysis of data based on qualititative research depending on Saiki Greig Hill theory. The summary of this is as follows; perception and attitudes about disables parents tended to strengthen the steps 'process of recognition about disabled parents', 'process of escape about disabled parents',' precess of integration about disabled parents'. The alternative programs of the strengthen the steps 'process of integration about disabled parents' should be developed government policy support according to age group, ADL(activity of daily life) support according to disability status and emotional support with a focused on health family support center, public health center, religion meeting. This study was to provided basic material needed to do further research on this issue by identifying the effects of family-of-origin environment on adult offsprings with disabled parents.

• Korean Journal of Human Ecology
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• v.17 no.2
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• pp.191-205
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• 2008

The study aims at exploring a general trend of psychological well-being (PWB) of elderly volunteers and analyzing the variables which give effects on their PWB. The subjects were two hundred men and women over 60 years old currently participating in voluntary service. The data collected from interviewing were analyzed by descriptive statistics, $x^2$ test, Pearson's correlation and hierarchical multiple regression. The main results are: First, PWB of the elderly is higher than the average score of PWB. Second, the elderly's generativity is positively related to PWB. Family support such as an emotional and instrumental support was also positively related to PWB. Third, the variables effecting on PWB of elderly volunteers were education level, participation frequency, generativity level, and an instrumental support of their family members on it. The lower their educational level was, the more frequently they participated in voluntary activity, the higher their generativity level was, and the more support given from their family, the higher PWB scores they showed.

• Journal of Korean Academy of Nursing
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• v.42 no.5
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• pp.680-688
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• 2012

Purpose: The purposes of this study were to explore the effects of family cohesion and subjective happiness on death anxiety of Korean elders and to identify other factors contributing to death anxiety. Methods: The participants were 280 elders who lived in P metropolitan city. Data were collected between November 5, 2011 and January 12, 2012 using the Short Portable Mental Status Questionnaire (SPMSQ), Family Cohesion Evaluation Scale, Subjective Happiness Scale, and Fear of Death Scale (FODS). Data were analyzed using the SPSS/WIN 19.0 program. Results: Family cohesion, marital status, religious activity, perceived health status, and subjective happiness were included in the factors affecting death anxiety of Korean elders. These variables explained 50.1% of death anxiety. Conclusion: The results of the study indicate that these variables should be considered in developing nursing intervention programs to decrease death anxiety and increase family cohesion and subjective happiness for life integration in Korean elders.

• Journal of East-West Nursing Research
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• v.12 no.1
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• pp.33-42
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• 2006

Purpose: This study was a descriptive study to compare of quality of life, relationship with CVA patients, and family support between caregiver of patient with CVA in western and oriental medicine. Method: Total 270 caregivers for CVA patients were selected from western medicine department (114) and oriental medicine department (156) at K hospital in Seoul. The instrument tools utilized in this study were quality of life, Family support, Caregiver's relationship with patients, daily activity. Collected data were analyzed by $X^2$-test, t-test using SPSS Windows 12.0 Program. Result: The result are as follows: 1) There was no significant difference in quality of life between caregivers of patients with CVA in western and oriental medicine(t=.26, p=.792). 2) There was significant difference in relationship with patients(t=2.64, p=.009) and family support(t=2.12, p=.035) before onset of disease between caregivers of patients with CVA in western and oriental medicine. Conclusion: As a result, caregivers of oriental medicine with CVA patients showed closer relationship with patients before the onset of disease and higher family support compare to caregivers of western medicine with CVA patients.

• Molecules and Cells
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• v.42 no.1
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• pp.1-7
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• 2019

Macrophage is an important innate immune cell that not only initiates inflammatory responses, but also functions in tissue repair and anti-inflammatory responses. Regulating macrophage activity is thus critical to maintain immune homeostasis. Tyro3, Axl, and Mer are integral membrane proteins that constitute TAM family of receptor tyrosine kinases (RTKs). Growing evidence indicates that TAM family receptors play an important role in anti-inflammatory responses through modulating the function of macrophages. First, macrophages can recognize apoptotic bodies through interaction between TAM family receptors expressed on macrophages and their ligands attached to apoptotic bodies. Without TAM signaling, macrophages cannot clear up apoptotic cells, leading to broad inflammation due to over-activation of immune cells. Second, TAM signaling can prevent chronic activation of macrophages by attenuating inflammatory pathways through particular pattern recognition receptors and cytokine receptors. Third, TAM signaling can induce autophagy which is an important mechanism to inhibit NLRP3 inflammasome activation in macrophages. Fourth, TAM signaling can inhibit polarization of M1 macrophages. In this review, we will focus on mechanisms involved in how TAM family of RTKs can modulate function of macrophage associated with anti-inflammatory responses described above. We will also discuss several human diseases related to TAM signaling and potential therapeutic strategies of targeting TAM signaling.

• BMB Reports
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• v.39 no.2
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• pp.223-227
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• 2006

Dihydrolipoamide dehydrogenase (E3) belongs to the pyridine nucleotide-disulfide oxidoreductase family including glutathione reductase and thioredoxin reductase. It catalyzes the reoxidation of dihydrolipoyl moiety of the acyltransferase components of three $\alpha$-keto acid dehydrogenase complexes and of the hydrogen-carrier protein of the glycine cleavage system. Isoleucine-51 of human E3, located near the active disulfide center Cys residues, is highly conserved in most E3s from several sources. To examine the importance of this highly conserved Ile-51 in human E3 function, it was substituted with Ala using site-directed mutagenesis. The mutant was expressed in Escherichia coli and highly purified using an affinity column. Its E3 activity was decreased about 100-fold, indicating that the conservation of the Ile-51 residue in human E3 was very important to the efficient catalytic function of the enzyme. Its altered spectroscopic properties implied that conformational changes could occur in the mutant.

• Journal of the Korean Home Economics Association
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• v.50 no.4
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• pp.63-71
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• 2012

This study aimed to investigate the job satisfaction of child care helpers who are service providers in a child care support project. For this study, 302 child care helpers in ten districts within Seoul participated in the present study. A survey was conducted to collect data concerning their job satisfaction. Data were analyzed with descriptive statistics and regression using the SPSSWin 16.0 version. The results of this study were as follows. Generally, child care helpers had a high degree of job satisfaction. In addition, they exhibited the highest degree of satisfaction in relationships and the lowest satisfaction in wages. Furthermore, they demonstrated varying degrees of job satisfaction depending on their individual characteristics, activity characteristics, and activity recognition. The results of the present study can provide useful implications in regards to successful child care support projects.

• Journal of the Korean Home Economics Association
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• v.45 no.4
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• pp.29-42
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• 2007

The purpose of this study is to investigate the leisure and social support types which affect elderly depression. The study sample comprised 275 cases, and the analysis was performed by t-test, ANOVA, multiple regression and stepwise regression on SPSS ver. 10.0. The following three principle results were obtained: First, the types of leisure and social support differed according to domographic profiles. Second, among 6 sub-factors of leisure type, sports and viewing impressions activities contributed positively to elderly depression, as did emotional and appraisement supports among 4 sub-factors of social support. Third, stepwise regression analysis, conducted to determine the effect weights of factors of leisure types and social supports, showed that emotional support, social relationships activity, and viewing impressions activity strongly affected elderly depression in the order listed. Based of these results, the study suggested methods for developing an active leisure activities program which is necessary to minimize elderly depression.